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Early Results of Estrogen PATCH trial - 1
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Prostate Cancer Network
5 months ago
Results
Hi everyone I posted a couple of weeks ago and was advised to have bloods done. These are my results so hoping for further advice in supplementing or adjusting doseage. I currently take 50mcg Levothyroxine and 25mcg T3 daily. I also have B12 injections every 12wks. Latest B12 injection given day after
Hi everyone I posted a couple of weeks ago and was advised to have bloods done. These are my results so hoping for further advice in supplementing or adjusting doseage. I currently take 50mcg Levothyroxine and 25mcg T3 daily. I also have B12 injections every 12wks. Latest B12 injection given day after
Pixie50
in
Thyroid UK
5 months ago
Estrogen ADT vs Lupron ADT
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
janebob99
in
Prostate Cancer Network
5 months ago
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Benefits of Estrogen Patch Therapy
Here's a chart summarizing the benefits and detriments of modern Estrogen Patch Therapy, supported by numerous publications. Overall, the large numbers of benefits outweighs the few negatives.
Here's a chart summarizing the benefits and detriments of modern Estrogen Patch Therapy, supported by numerous publications. Overall, the large numbers of benefits outweighs the few negatives.
janebob99
in
Prostate Cancer Network
5 months ago
No Osteoporosis with Estrogen Patch Therapy
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
janebob99
in
Prostate Cancer Network
5 months ago
Castration by Estrogen Patch
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
janebob99
in
Prostate Cancer Network
5 months ago
Transdermal estrogen/estradiol as monotherapy for Prostate Cancer
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Lost_Sheep
in
Prostate Cancer Network
5 months ago
9 years survivor
I had grade 2 ductal breast cancer late 2014 when I had just turned 60 I had surgery , Chemotherapy (and radiotherapy it was hormone related Her2
oestrogen
and progesterone positive I also had 18 doses of Herceptin So I had belts and braces as the oncologist said I have also been on letrazole
I had grade 2 ductal breast cancer late 2014 when I had just turned 60 I had surgery , Chemotherapy (and radiotherapy it was hormone related Her2
oestrogen
and progesterone positive I also had 18 doses of Herceptin So I had belts and braces as the oncologist said I have also been on letrazole
4951
in
My Breast Cancer Community
1 year ago
Oestrogen only HRT
Does anyone have any experience of taking
oestrogen
only HRT after a partial hysterectomy? I've been recommended this,by a BSGE consultant, but didn't think that
oestrogen
only was a good option and now I'm really confused.
Does anyone have any experience of taking
oestrogen
only HRT after a partial hysterectomy? I've been recommended this,by a BSGE consultant, but didn't think that
oestrogen
only was a good option and now I'm really confused.
Albicat
in
Endometriosis UK
1 year ago
Perimenopause symptoms
hello.. since about November I started to experience neck tightness, warm feeling in a spot of my scalp, tense shoulders., I also had a period at that time. I’ve been keeping notes and noticed in mid Dec and Jan 20th I experienced the same symptoms, though I had no period. Around Feb 15th I started
hello.. since about November I started to experience neck tightness, warm feeling in a spot of my scalp, tense shoulders., I also had a period at that time. I’ve been keeping notes and noticed in mid Dec and Jan 20th I experienced the same symptoms, though I had no period. Around Feb 15th I started
Lvdmarte76
in
Menopause and Perimenopause Support
5 months ago
HRt - side effects
Hi I’ve recently started 2 pumps of oestrogel per day. Has anyone else experienced strong nausea and loss of appetite when starting this? It is concerning me. Kind Regards Lara
Hi I’ve recently started 2 pumps of oestrogel per day. Has anyone else experienced strong nausea and loss of appetite when starting this? It is concerning me. Kind Regards Lara
Lara1244
in
Menopause and Perimenopause Support
6 days ago
Estrogen Priming - Cycle 2
For my second cycle my consultant has suggested doing 7 days worth of Estrogen priming before i start my stims - apparently it helps to encourage follicles to grow at a steady rate together rather than some firing ahead. Has anyone had experience of this, did it help? TIA xx
For my second cycle my consultant has suggested doing 7 days worth of Estrogen priming before i start my stims - apparently it helps to encourage follicles to grow at a steady rate together rather than some firing ahead. Has anyone had experience of this, did it help? TIA xx
Greenleaves1
in
Fertility Network UK
5 months ago
Failed implantation - what tests should I get to investigate and is the NHS likely to take them into consideration?
Hi, I was lucky enough to get NHS funding for IVF. Had one FET so far and it failed to implant. If I wanted to get tests in private to investigate implantation failure, which ones should I get, and are NHS consultants likely to take them into consideration or am I wasting money?I have a positive test
Hi, I was lucky enough to get NHS funding for IVF. Had one FET so far and it failed to implant. If I wanted to get tests in private to investigate implantation failure, which ones should I get, and are NHS consultants likely to take them into consideration or am I wasting money?I have a positive test
LondonBase
in
Fertility Network UK
5 months ago
Any red flags in these results or am I barking up wrong tree?
I have the Mirena fitted and am currently on 3 pumps
oestrogen
. My issue is that I am extremely fatigued and struggling to cope with the activities of a normal day and have been feeling this way for several months.
I have the Mirena fitted and am currently on 3 pumps
oestrogen
. My issue is that I am extremely fatigued and struggling to cope with the activities of a normal day and have been feeling this way for several months.
ducky1971
in
Thyroid UK
1 year ago
10 weeks in, not feeling great
I am a 57 year old woman, and had an Nstemi 10 weeks ago, and one stent fitted. I am on 2.5 bisoprolol, tricagrelor, 10 of ramipril, 80 statins and also aspirin. My ejection fraction was poor at 45 (which I found a bit upsetting when it transpired I was the lowest in the rehab class) I was on HRT before
I am a 57 year old woman, and had an Nstemi 10 weeks ago, and one stent fitted. I am on 2.5 bisoprolol, tricagrelor, 10 of ramipril, 80 statins and also aspirin. My ejection fraction was poor at 45 (which I found a bit upsetting when it transpired I was the lowest in the rehab class) I was on HRT before
Pinksock2
in
British Heart Foundation
22 days ago
Is this thyroid?
hi there, I have been struggling with what I thought was Peri menopause/menopause symptoms for a while (dizzy spells, headaches, brain fog, dry eyes, fatigue etc) Last year these symptoms got progressively worse with pain under left arm in lymph node and weakness to the point I felt like collapsing
hi there, I have been struggling with what I thought was Peri menopause/menopause symptoms for a while (dizzy spells, headaches, brain fog, dry eyes, fatigue etc) Last year these symptoms got progressively worse with pain under left arm in lymph node and weakness to the point I felt like collapsing
Dublinlady
in
Thyroid UK
5 months ago
IVF 1st cycle - 9 eggs only 2 embryos for frozen embryo transfer
Hello lovely ladies, I’m new to hear and wanted to share my story , I’ve been reading some other posts and it’s really helped. Hope my post can also support anyone else also going through similar. Started my first round of IVF cycle last month with donor sperm as my husband sadly has non obstructive
Hello lovely ladies, I’m new to hear and wanted to share my story , I’ve been reading some other posts and it’s really helped. Hope my post can also support anyone else also going through similar. Started my first round of IVF cycle last month with donor sperm as my husband sadly has non obstructive
Clementine2021
in
Fertility Network UK
5 months ago
Advice for estrogen vaginal cream
I've been using Estradiol (vaginal estrogen cream) for about a year or so. I've always used the applicator to apply the cream but I'm wondering if I can just smear the cream on with my finger. How many of you ladies apply the cream with your finger? I'm afraid if I don't use the applicator and don't
I've been using Estradiol (vaginal estrogen cream) for about a year or so. I've always used the applicator to apply the cream but I'm wondering if I can just smear the cream on with my finger. How many of you ladies apply the cream with your finger? I'm afraid if I don't use the applicator and don't
sungirl55
in
Menopause and Perimenopause Support
5 months ago
Estradiol E2 results 119pmol/L
I was scheduled to start my IVF circle this month but has been postponed ,the doctor is saying my estrogen level is high at 119pmol/L on day 2 ,Im confused tmsince if i convert this level in pg\nl is 32.4, please share your views on this.Thanks
I was scheduled to start my IVF circle this month but has been postponed ,the doctor is saying my estrogen level is high at 119pmol/L on day 2 ,Im confused tmsince if i convert this level in pg\nl is 32.4, please share your views on this.Thanks
KHMSJ
in
Fertility Network UK
5 months ago
ovulation after failed medicated fet
hi everyone , Did anyone else experience no ovulation after a medicated fet ? Im literally getting no hint of a line on my ovulation tests , I always have some lh in my system . I am meant to be going for a natural fet so desperately want to get my natural cycles back. Im normally like clockwork but
hi everyone , Did anyone else experience no ovulation after a medicated fet ? Im literally getting no hint of a line on my ovulation tests , I always have some lh in my system . I am meant to be going for a natural fet so desperately want to get my natural cycles back. Im normally like clockwork but
Natasha2012
in
Fertility Network UK
5 months ago
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