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2nd pBAT cycle results: AR upregulation? Double strand breaks? Darolutamide?
Started 2nd pBAT cycle on 4-22-24 with a PSA of 0.62 measured 2 days earlier. All 6 injections were 50 mg eod of T propionate with .625 mg letrozole every 5th day as an aromatase inhibitor. The hiT cycle was cut short by 2 injections because of a plan to SBRT treat a pelvic lymph node chain that lit
Started 2nd pBAT cycle on 4-22-24 with a PSA of 0.62 measured 2 days earlier. All 6 injections were 50 mg eod of T propionate with .625 mg letrozole every 5th day as an aromatase inhibitor. The hiT cycle was cut short by 2 injections because of a plan to SBRT treat a pelvic lymph node chain that lit
Ichthus316
in
Fight Prostate Cancer
2 months ago
Latest results, any opinions please?
Latest results above, on 150mg T4 (Roseway own compounded with rice flour) for the 6 weeks leading up to the test, test done at 7:45am due to practicalities, fasted, last dose 24 hours before, off thorne basic b's for the week beforehand... Lab is Inuvi, previous comments have suggested their ranges
Latest results above, on 150mg T4 (Roseway own compounded with rice flour) for the 6 weeks leading up to the test, test done at 7:45am due to practicalities, fasted, last dose 24 hours before, off thorne basic b's for the week beforehand... Lab is Inuvi, previous comments have suggested their ranges
FoggyThinker
in
Thyroid UK
2 months ago
The 2024 Advanced Prostate Cancer Consensus Conference (APCCC) meeting-- Chock full of Testosterone...
Greetings FPC Forum Dwellers, Marnie passed me some solid information on the APCCC...and it is all about testosterone... I got you looking now !!! First, the warmup with a case study and the message that when it comes to testosterone recovery, short term ADT can take 18 months and long term ADT to 2
Greetings FPC Forum Dwellers, Marnie passed me some solid information on the APCCC...and it is all about testosterone... I got you looking now !!! First, the warmup with a case study and the message that when it comes to testosterone recovery, short term ADT can take 18 months and long term ADT to 2
NPfisherman
in
Fight Prostate Cancer
2 months ago
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Anxiety and panic attacks
Hello, I am a newbie... I have been SI every other day for 6 weeks. I had increased anxiety and a panic attack after my last couple of injections so have not injected for the past 2 weeks, but my anxiety/panic and trouble sleeping have continued. My doctor said he has never seen this in any of this
Hello, I am a newbie... I have been SI every other day for 6 weeks. I had increased anxiety and a panic attack after my last couple of injections so have not injected for the past 2 weeks, but my anxiety/panic and trouble sleeping have continued. My doctor said he has never seen this in any of this
Krysagnes
in
Pernicious Anaemia Society
2 months ago
Started HRT - Increased need to urinate - will this get better?
Hello Ladies I have just started HRT and I have some unpleasant side effects. I now seem to need the loo every 20min. It’s an urge and I don't feel I can empty my bladder. It’s affecting my life as I struggle to take journeys on the train or in the car. Is this normal? Will this get better? Thank
Hello Ladies I have just started HRT and I have some unpleasant side effects. I now seem to need the loo every 20min. It’s an urge and I don't feel I can empty my bladder. It’s affecting my life as I struggle to take journeys on the train or in the car. Is this normal? Will this get better? Thank
PixieElv
in
Menopause and Perimenopause Support
2 months ago
How you can help make ibrutinib plus venetoclax fixed duration therapy a reality for Australians with previously untreated CLL
In Australia, no new medicine can be listed on the Pharmaceutical Benefits Scheme (PBS) unless it has first been recommended by the Pharmaceutical Benefits Advisory Committee (PBAC). In March 2024, PBAC will again consider a submission to recommend a 15-month combination therapy of ibrutinib plus venetoclax
In Australia, no new medicine can be listed on the Pharmaceutical Benefits Scheme (PBS) unless it has first been recommended by the Pharmaceutical Benefits Advisory Committee (PBAC). In March 2024, PBAC will again consider a submission to recommend a 15-month combination therapy of ibrutinib plus venetoclax
CLLerinOz
Administrator
in
CLL Support
9 months ago
Gynae appointment
Hi All, Needing some advice as I have finally got a gynae appointment next month and need to know what to ask about and what I want. For some history, in 2000 I have been diagnosed with PCOS, 2005 Stage 1 Endo, 2021 Stage 4 Endo with uterus and ovaries stuck to bowel and Fibroids and Adenomyosis, which
Hi All, Needing some advice as I have finally got a gynae appointment next month and need to know what to ask about and what I want. For some history, in 2000 I have been diagnosed with PCOS, 2005 Stage 1 Endo, 2021 Stage 4 Endo with uterus and ovaries stuck to bowel and Fibroids and Adenomyosis, which
LawsTra
in
Endometriosis UK
2 months ago
Diagnosed at 61
I had a my first tonic clonic seizure June 23. I'd been having focal seizures for 10 years but didn't know what they were, so never saw the doctor. I've had CT scan, MRI and all normal. Had an ECT and that showed abnormal electrical activity in my brain which shocked me. I started Lamotrigine in July
I had a my first tonic clonic seizure June 23. I'd been having focal seizures for 10 years but didn't know what they were, so never saw the doctor. I've had CT scan, MRI and all normal. Had an ECT and that showed abnormal electrical activity in my brain which shocked me. I started Lamotrigine in July
TheCoulerPurple
in
Epilepsy Action
6 months ago
Has anyone tried HRT to help with migraines?
I have never been on HRT and went through the menopause seven years ago but have recently heard about how lack of oestrogen can add to migraines which I’ve suffered from for many years. Have you had any experience of HRT helping migraines ? Thanks!
I have never been on HRT and went through the menopause seven years ago but have recently heard about how lack of oestrogen can add to migraines which I’ve suffered from for many years. Have you had any experience of HRT helping migraines ? Thanks!
Headache123
in
Migraine Support
2 months ago
1 Yr on pBAT Results
Hi fellow warriors. After one year of Orgovyx and Darolutamide and still hormone sensitive i decided to change to a testosterone propionate BAT protocol (Russ' Protocol) Here is a graph of my PSA numbers. all the peaks were taken after or during high T cycle. The Highest Peak is 2.46 and lowest 0.03
Hi fellow warriors. After one year of Orgovyx and Darolutamide and still hormone sensitive i decided to change to a testosterone propionate BAT protocol (Russ' Protocol) Here is a graph of my PSA numbers. all the peaks were taken after or during high T cycle. The Highest Peak is 2.46 and lowest 0.03
KocoPr
in
Fight Prostate Cancer
2 months ago
ovary removed, womb with mirena coil still there . Now in full menopause has anyone else been thru this ? Wot was your journey?
they suspected ovarian cancer so was operated on 2 weeks ago where there the plan was full hysterectomy but they where unable to do this due to severe endo n womb adhered to bowel so badly id have ended up with s stoma n as ovarian tumour there was no rational to take such extreme measures. So ovaries
they suspected ovarian cancer so was operated on 2 weeks ago where there the plan was full hysterectomy but they where unable to do this due to severe endo n womb adhered to bowel so badly id have ended up with s stoma n as ovarian tumour there was no rational to take such extreme measures. So ovaries
madtabby
in
Endometriosis UK
2 months ago
Improved chances of success with ADT?
I'm a Gleason 4+3, group T2C. I completed five sessions of SBRT but the radiation oncologist says staying on Lupron for six months total will improve the odds of success. What I see online, though, is that ADT only improves the odds of success by 1-2 percentage points. If that's the case, it's not worth
I'm a Gleason 4+3, group T2C. I completed five sessions of SBRT but the radiation oncologist says staying on Lupron for six months total will improve the odds of success. What I see online, though, is that ADT only improves the odds of success by 1-2 percentage points. If that's the case, it's not worth
ADT-first-timer
in
Advanced Prostate Cancer
2 months ago
Mortality Risk Up for Cancer Survivors With Elevated Loneliness
Especially with men on ADT with the attendant mood swings, depression, fat gain, & loss of libido, I can see how that could occur. https://www.practiceupdate.com/news/45931/2/1?elsca1=emc_enews_daily-digest&elsca2=email&elsca3=practiceupdate_onc&elsca4=oncology&elsca5=newsletter&rid=MjgxNTg3Njk1MzQzS0&
Especially with men on ADT with the attendant mood swings, depression, fat gain, & loss of libido, I can see how that could occur. https://www.practiceupdate.com/news/45931/2/1?elsca1=emc_enews_daily-digest&elsca2=email&elsca3=practiceupdate_onc&elsca4=oncology&elsca5=newsletter&rid=MjgxNTg3Njk1MzQzS0&
dockam
in
Advanced Prostate Cancer
2 months ago
Enzalutamide Plus 5-Alpha Reductase Inhibitors for Castrate-Sensitive Prostate Cancer
Phase II trial exploring the combination of enzalutamide with five alpha-reductase inhibitors (ARIs) for castrate-sensitive prostate cancer. Driven by observations from geriatric oncology, the study seeks alternatives to androgen deprivation therapy (ADT) for older, frail men who struggle with its side
Phase II trial exploring the combination of enzalutamide with five alpha-reductase inhibitors (ARIs) for castrate-sensitive prostate cancer. Driven by observations from geriatric oncology, the study seeks alternatives to androgen deprivation therapy (ADT) for older, frail men who struggle with its side
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
Signifficant PSA LEVELS
I'm an 81 year old man who has had an enlarged prostate for several months. PSA tests levels 9.1 and 8.1 (several months apart). My Father died of prostate cancer, which had spread to other parts of his body. Follwing a Digital Anal test, my prostate was reported as "smoothly enlarged and sulcus palpable
I'm an 81 year old man who has had an enlarged prostate for several months. PSA tests levels 9.1 and 8.1 (several months apart). My Father died of prostate cancer, which had spread to other parts of his body. Follwing a Digital Anal test, my prostate was reported as "smoothly enlarged and sulcus palpable
apttony
in
Prostate Cancer Network
2 months ago
Does PSA drop after starting ADT tell us anything?
My husband started Firmagon shots a month ago. Before starting his PSA was 5.9. It was tested a few days ago and it’s 1.4 now. Does this tell us anything of any significance? Thanks!
My husband started Firmagon shots a month ago. Before starting his PSA was 5.9. It was tested a few days ago and it’s 1.4 now. Does this tell us anything of any significance? Thanks!
EvFC
in
Advanced Prostate Cancer
2 months ago
Terrible sleep issues
So now I’m 10+ weeks into treatment consisting of Lupron+Abiraterrone and have completed 5 of 20 radiation sessions. In many ways things seem to be going very well. My PSA numbers have gone from 8.4 to .2 and still falling. My side effects have been minimal , only lately have I seen some mild hot
So now I’m 10+ weeks into treatment consisting of Lupron+Abiraterrone and have completed 5 of 20 radiation sessions. In many ways things seem to be going very well. My PSA numbers have gone from 8.4 to .2 and still falling. My side effects have been minimal , only lately have I seen some mild hot
Willie51
in
Prostate Cancer And Gay Men
2 months ago
Why is my RO changing from Degerelix to Lupron after a month?
my husband started ADT treatment and RO informed him that after a month he will switch to Lupron. Is there a reason why he is doing this? As Lupron I read causes depression, anxiety. And if hopefully Degerelix works why change it? Can we request he not ? TIA.
my husband started ADT treatment and RO informed him that after a month he will switch to Lupron. Is there a reason why he is doing this? As Lupron I read causes depression, anxiety. And if hopefully Degerelix works why change it? Can we request he not ? TIA.
SherryKahn
in
Advanced Prostate Cancer
2 months ago
Interpreting blood tests
I've been on ADT for 4 months in preparation for RT and then HDR BT. I have localised G8 with an initial PSA of 8.1 Prior to commencing ADT, my PSA inexplicably dropped to 4.94 but then rose to 5.37 within 2 months. Anyway, here are my test results before starting ADT; These are Aussie measurements
I've been on ADT for 4 months in preparation for RT and then HDR BT. I have localised G8 with an initial PSA of 8.1 Prior to commencing ADT, my PSA inexplicably dropped to 4.94 but then rose to 5.37 within 2 months. Anyway, here are my test results before starting ADT; These are Aussie measurements
Mike58
in
Advanced Prostate Cancer
2 months ago
Finally got a diagnosis of Endometriosis today
I've been on such a journey with my pelvic pain. I'm 50 and I had a hysterectomy 4 months ago for fibroids. A laparoscopy ruled out Endo last year. I was pain free for the first time in months. I started hrt and my original pains 6 weeks ago came back with a vengeance just like they did last year when
I've been on such a journey with my pelvic pain. I'm 50 and I had a hysterectomy 4 months ago for fibroids. A laparoscopy ruled out Endo last year. I was pain free for the first time in months. I started hrt and my original pains 6 weeks ago came back with a vengeance just like they did last year when
Mindfullness4791
in
Endometriosis UK
2 months ago
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