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Time to PSA Nadir is related to progression-free-survival
This graph from Teoh (2014) plots the relationship between Time to PSA Nadir (months) versus Time to Progression (months) (i.e., Progression Free Survival). Cohort: ADT monotherapy (No RP or RT), all metastatic patients, median 74 y.o., GS = 8-10, N=419. A cubic spline curve fit matched the data points
This graph from Teoh (2014) plots the relationship between Time to PSA Nadir (months) versus Time to Progression (months) (i.e., Progression Free Survival). Cohort: ADT monotherapy (No RP or RT), all metastatic patients, median 74 y.o., GS = 8-10, N=419. A cubic spline curve fit matched the data points
janebob99
in
Advanced Prostate Cancer
6 months ago
Abiraterone seems to be working
An update on my situation. To review, I now appear to be castrate resistant after about 6 1/2 years of being castrate sensitive. My MO put me on Abiraterone, along the existing Lupron. I had my MO appt and my PSA has fallen from 4.5 to 2 after about 7 weeks on Abi. This is my second iteration with Abi
An update on my situation. To review, I now appear to be castrate resistant after about 6 1/2 years of being castrate sensitive. My MO put me on Abiraterone, along the existing Lupron. I had my MO appt and my PSA has fallen from 4.5 to 2 after about 7 weeks on Abi. This is my second iteration with Abi
fireandice123
in
Advanced Prostate Cancer
6 months ago
B12 website - Norway (Norge / Noreg)
This has probably been mentioned before but just thought I'd post it for any forum members from Norway. B12-Foreningen https://www.b12-foreningen.no/ Another link for Norway below. https://www.b12info.com/very-useful-links/ PAS (Pernicious Anaemia Society) accepts members from across the world.
This has probably been mentioned before but just thought I'd post it for any forum members from Norway. B12-Foreningen https://www.b12-foreningen.no/ Another link for Norway below. https://www.b12info.com/very-useful-links/ PAS (Pernicious Anaemia Society) accepts members from across the world.
Sleepybunny
in
Pernicious Anaemia Society
3 months ago
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Cortisol test
Result of morning cortisal test was 131 which is rubbish (range 102-535) and explains why I feel exhausted some days. Have been on 3mg for several weeks. Looks like it’s a Synacthen test next. Thanks PMRpro for the info on that. Is the experience ok anyone out there who’s had one?
Result of morning cortisal test was 131 which is rubbish (range 102-535) and explains why I feel exhausted some days. Have been on 3mg for several weeks. Looks like it’s a Synacthen test next. Thanks PMRpro for the info on that. Is the experience ok anyone out there who’s had one?
Bluey-1
in
PMRGCAuk
6 months ago
Insertable Cardiac Monitor (ICM)
An Insertable Cardiac Monitor (ICM) is a small thin device that is inserted under the skin to record the activity of your heart. The ICM monitors and records your heart’s electrical activity in order to identify any changes to the heart rhythm. You may be experiencing symptoms that indicate you have
An Insertable Cardiac Monitor (ICM) is a small thin device that is inserted under the skin to record the activity of your heart. The ICM monitors and records your heart’s electrical activity in order to identify any changes to the heart rhythm. You may be experiencing symptoms that indicate you have
SamAdmin
Administrator
in
Sudden Cardiac Arrest & Heart Attack
1 day ago
Does anyone have experience of how Large Vessel Vasculitis (GCA /TA) may be affected by a long haul flight?
I’ve never experienced a long haul flight and, as we prefer to drive when we holiday abroad, I haven’t been on a plane for 15 years but I am booked to go to S Korea next week to visit my granddaughter who is currently teaching in Seoul. In August I was diagnosed with Large Vessel Vasculitis and the consultant
I’ve never experienced a long haul flight and, as we prefer to drive when we holiday abroad, I haven’t been on a plane for 15 years but I am booked to go to S Korea next week to visit my granddaughter who is currently teaching in Seoul. In August I was diagnosed with Large Vessel Vasculitis and the consultant
Obscureclouds
in
Vasculitis UK
1 day ago
Atrial Fibrillation
I was diagnosed with A-Flutter 3 years ago by an Electrophysiologist that came to work for the Cardiology department of the Cardiologist I have been seeing for several years because of an artificial mitral heart valve. She informed me that I had been in A-Flutter for approximately one year. The only
I was diagnosed with A-Flutter 3 years ago by an Electrophysiologist that came to work for the Cardiology department of the Cardiologist I have been seeing for several years because of an artificial mitral heart valve. She informed me that I had been in A-Flutter for approximately one year. The only
Lizilue
in
Hughes Syndrome APS Forum
3 days ago
amiadrone
For those of you with hypothyroidism and heart disease, have any of you been advised to or taken amiadrone and warfarin prior to cardioversion to increase likelihood of staying in sinus rhythm? There are so many contraindications for me personally due to other meds and comorbidities.
For those of you with hypothyroidism and heart disease, have any of you been advised to or taken amiadrone and warfarin prior to cardioversion to increase likelihood of staying in sinus rhythm? There are so many contraindications for me personally due to other meds and comorbidities.
bikebabe
in
Thyroid UK
3 days ago
amiadrone
For those of you with hypothyroidism and heart disease, have any of you been advised to or taken amiadrone and warfarin prior to cardioversion to increase likelihood of staying in sinus rhythm? There are so many contraindications for me personally due to other meds and comorbidities.
For those of you with hypothyroidism and heart disease, have any of you been advised to or taken amiadrone and warfarin prior to cardioversion to increase likelihood of staying in sinus rhythm? There are so many contraindications for me personally due to other meds and comorbidities.
bikebabe
in
Thyroid UK
3 days ago
warfarin and chia seeds
Hi I self test my INR. I want to introduce chia seeds as part of my daily diet. I know they can interact with anticoagulants. I take Warfarin. Has anybody had any experience with warfarin and chia. it says on the net it doesnt mean no. But exercise caution. Presumably, it could raise my INR so
Hi I self test my INR. I want to introduce chia seeds as part of my daily diet. I know they can interact with anticoagulants. I take Warfarin. Has anybody had any experience with warfarin and chia. it says on the net it doesnt mean no. But exercise caution. Presumably, it could raise my INR so
Gilli54
in
Anticoagulation Support
4 days ago
Now Dr. Mandrola not only likes, but loves Pulse Field Ablation (PFA).
Dr. John Mandrola previously had reservations about Pulse Field Ablation being a breakthrough in treating afib. Npw that he has personally seen it in action, he has changed his mind. From his Substack 11/22 "Now I have used PFA. And. It is somewhat amazing. It ablates cardiac tissue quickly and
Dr. John Mandrola previously had reservations about Pulse Field Ablation being a breakthrough in treating afib. Npw that he has personally seen it in action, he has changed his mind. From his Substack 11/22 "Now I have used PFA. And. It is somewhat amazing. It ablates cardiac tissue quickly and
mjames1
in
Atrial Fibrillation Support
4 days ago
Where Is Data Stored for Wellue's ECG Traces?
I have had a Wellue ECG device for a few days -- the kind that can record heartbeats for up to 24 hours. When I review one of these recordings, I can immediately see the ECG tracings. The file with these tracings can be hundreds of screens long, one screen per minute of recording time. You can advance
I have had a Wellue ECG device for a few days -- the kind that can record heartbeats for up to 24 hours. When I review one of these recordings, I can immediately see the ECG tracings. The file with these tracings can be hundreds of screens long, one screen per minute of recording time. You can advance
Corazon17
in
Atrial Fibrillation Support
4 days ago
Biologics - when/did you move up to them?
Trying to get a measure of the stages and various meds that treat lupus, and wondering if/when anyone was moved up to biologics like Belimumab and Rituximab. I understand lupus is treated softly softly, as in mildest immune suppressants first and gradually move up the ladder, and biologics are stronger
Trying to get a measure of the stages and various meds that treat lupus, and wondering if/when anyone was moved up to biologics like Belimumab and Rituximab. I understand lupus is treated softly softly, as in mildest immune suppressants first and gradually move up the ladder, and biologics are stronger
smeackles
in
LUPUS UK
5 days ago
angiogram update
Hi all, Just a quick update for anyone that is interested, I went for the cardiac angiogram on Friday and apart from a few bruises and a rash, probably a reaction to the contrast dye, I seem to be okay, however no intervention was carried out because the findings didn’t correlate with the CT angiogram
Hi all, Just a quick update for anyone that is interested, I went for the cardiac angiogram on Friday and apart from a few bruises and a rash, probably a reaction to the contrast dye, I seem to be okay, however no intervention was carried out because the findings didn’t correlate with the CT angiogram
Buttsy
in
Scleroderma & Raynaud's UK (SRUK)
5 days ago
DRUGS
Good afternoon. I take 50mg Flecainide morning and night. 1.25mg Bisoprolol mornings. 4mg Candesartan mornings and 20mg Xeralto at night. Heart rate is usually on the low side of normal even without Bisoprolol. Two years ago when I started these drugs the recommended dose of Bisoprolol was 5mg and
Good afternoon. I take 50mg Flecainide morning and night. 1.25mg Bisoprolol mornings. 4mg Candesartan mornings and 20mg Xeralto at night. Heart rate is usually on the low side of normal even without Bisoprolol. Two years ago when I started these drugs the recommended dose of Bisoprolol was 5mg and
Afibtastic
in
Atrial Fibrillation Support
5 days ago
Help finding cardiologist - Bradycardia - West Herts NHS Trust (Will travel for good private Consultant)
Long story short..finally got GP to look at low bp (been low for 20 years but..) I asked for a different GP after being told time and time again 'some people have low heart rate!!). I've know somethings been wrong over past 18months. Electrocardiogram showed 'slow heart' and bp drop lying to to standing
Long story short..finally got GP to look at low bp (been low for 20 years but..) I asked for a different GP after being told time and time again 'some people have low heart rate!!). I've know somethings been wrong over past 18months. Electrocardiogram showed 'slow heart' and bp drop lying to to standing
auldreekie
in
Pernicious Anaemia Society
6 days ago
Medscape (AF and alcohol, for info)
Various studies have shown an association between alcohol use and atrial fibrillation. A study published in The New England Journal of Medicine in 2020 found that abstinence from alcohol reduced arrhythmia recurrences in regular drinkers with atrial fibrillation. Experts found that the effect of alcohol
Various studies have shown an association between alcohol use and atrial fibrillation. A study published in The New England Journal of Medicine in 2020 found that abstinence from alcohol reduced arrhythmia recurrences in regular drinkers with atrial fibrillation. Experts found that the effect of alcohol
maurice2
in
Atrial Fibrillation Support
6 days ago
chest pain
hello everyone, I was wondering if anybody experiences any kind of chest pain with endo or adeno? I’m not sure what causes this or if this is the cause but I have a feeling it could be one of these conditions. For the last couple of months I’ve massively felt chest pain on both sides, (mostly where
hello everyone, I was wondering if anybody experiences any kind of chest pain with endo or adeno? I’m not sure what causes this or if this is the cause but I have a feeling it could be one of these conditions. For the last couple of months I’ve massively felt chest pain on both sides, (mostly where
nightsky2
in
Endometriosis UK
6 days ago
CLL and heart failure
I am a 78 year old female. I was diagnosed with CLL in 2012, was on w&w until 2015, then had 4 rounds of chemotherapy. I have been on Imbruvica since 2020. Recently I had a ECT at my yearly physical and it was abnormal. The ECT I had in 2019 was normal. I had a heart ultrasound which shows that I have
I am a 78 year old female. I was diagnosed with CLL in 2012, was on w&w until 2015, then had 4 rounds of chemotherapy. I have been on Imbruvica since 2020. Recently I had a ECT at my yearly physical and it was abnormal. The ECT I had in 2019 was normal. I had a heart ultrasound which shows that I have
Judami
in
CLL Support
6 days ago
Did your ectopics die out after your ablation?
So, shortening a long story, AFib from age 40, successful ablation (PVI + flutter + mitral line) at age 48, 15 good years then an aortic dissection at age 63, the long OHS surgery for which put me back in Fib. Sinus for 5-1/2 years on Amiodarone but it was slowly weakening me, plus bad ectos. After
So, shortening a long story, AFib from age 40, successful ablation (PVI + flutter + mitral line) at age 48, 15 good years then an aortic dissection at age 63, the long OHS surgery for which put me back in Fib. Sinus for 5-1/2 years on Amiodarone but it was slowly weakening me, plus bad ectos. After
Cliff_G
in
Atrial Fibrillation Support
8 days ago
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