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In vivo: nanocarriers to deliver precision chemotherapy
A bit premature, but... Tests verified the ATP-modified PLGA nanoparticles were well tolerated in mice upon multiple systemic injections. They were able to recruit dendritic cells, the immune cells that recognize tumor antigens and bring specialized immune cells to fight off tumors. "Moreover, the
A bit premature, but... Tests verified the ATP-modified PLGA nanoparticles were well tolerated in mice upon multiple systemic injections. They were able to recruit dendritic cells, the immune cells that recognize tumor antigens and bring specialized immune cells to fight off tumors. "Moreover, the
Maxone73
in
Advanced Prostate Cancer
6 months ago
Adenmyosis and Constipation
I found out recently that adenmyosis can cause bad bouts of constipation, which explains a lot for me. However all the dr’s do is plug me with laxitives and tell me to eat prunes (which I have explained doesn’t help) because (and I apologise if this is TMI) my stools aren’t hard, it’s not a fibre intake
I found out recently that adenmyosis can cause bad bouts of constipation, which explains a lot for me. However all the dr’s do is plug me with laxitives and tell me to eat prunes (which I have explained doesn’t help) because (and I apologise if this is TMI) my stools aren’t hard, it’s not a fibre intake
SmallTalk
in
Endometriosis UK
3 months ago
Accuracy of PSMA PET scan?
What would you venture to guess is the accuracy of the PSMA PET scan? How many of you showed "no spread" with your PSMA scan, but then learned via surgery or otherwise that there WAS spread which wasn't detected with the PSMA scan? And, how much better is the new Posluma scan vs Pylarify? My husband
What would you venture to guess is the accuracy of the PSMA PET scan? How many of you showed "no spread" with your PSMA scan, but then learned via surgery or otherwise that there WAS spread which wasn't detected with the PSMA scan? And, how much better is the new Posluma scan vs Pylarify? My husband
Adendino
in
Advanced Prostate Cancer
6 months ago
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I was diagnosed with Behcets in 2018 followed by breast cancer in 2022. (Interesting to note inflammation in biopsy even for that). It was all fairly well controlled but I was not thriving as such and Nov 23 showed a new symptom - eye inflammation. Basically I read about a study in Birmingham where a
I was diagnosed with Behcets in 2018 followed by breast cancer in 2022. (Interesting to note inflammation in biopsy even for that). It was all fairly well controlled but I was not thriving as such and Nov 23 showed a new symptom - eye inflammation. Basically I read about a study in Birmingham where a
SCMW
in
Behçet's UK
3 months ago
Post laparotomy
Hello dear ladies, I am 5 days post my debulking surgery which went quite well. So far I have not had major issues… except bowel problems. Now they are talking about post op ileus or intestinal paralysis. Has anyone experienced this complication? What was done to treat it
Hello dear ladies, I am 5 days post my debulking surgery which went quite well. So far I have not had major issues… except bowel problems. Now they are talking about post op ileus or intestinal paralysis. Has anyone experienced this complication? What was done to treat it
Lara1
in
My Ovacome
3 months ago
Flagyl ( Metronidazole) Side Effects
Hi my friends, I was given Flagyl to treat my digestive system after an episode of food poisoning but this medicine caused a lot of annoying side effects like heartburn and bloating. Did any one had this medicine and how did you feel. Many thanks
Hi my friends, I was given Flagyl to treat my digestive system after an episode of food poisoning but this medicine caused a lot of annoying side effects like heartburn and bloating. Did any one had this medicine and how did you feel. Many thanks
Shoosh_kw
in
IBS Network
3 months ago
Mild TI inflammation
Hi, I've just had my third colonoscopy and I found it very painful. I was in agony during various times of it being done. I managed to get a report (some pictures this time too!) On the report they wrote for the procedure discomfort: Mild: More than 2 episodes of discomfort without distress. On my report
Hi, I've just had my third colonoscopy and I found it very painful. I was in agony during various times of it being done. I managed to get a report (some pictures this time too!) On the report they wrote for the procedure discomfort: Mild: More than 2 episodes of discomfort without distress. On my report
Sunita77
in
Bowel Disease Support
5 months ago
Post Op
Done my liver resection on 14 March 2024 coz found tumour in it since 2023. Went through Y90 treatment to shrink the tumour. Doc removed the tumour via keyhole with a drainage wound. After the op, stayed in hospital for 7 days till I’m stable and independent enough to walk on my own so wouldn’t be
Done my liver resection on 14 March 2024 coz found tumour in it since 2023. Went through Y90 treatment to shrink the tumour. Doc removed the tumour via keyhole with a drainage wound. After the op, stayed in hospital for 7 days till I’m stable and independent enough to walk on my own so wouldn’t be
SunnyShoe
in
British Liver Trust
6 months ago
Ivermectin Vs. Broccoli, etc. Video
I thought this was interesting and recently was posted. At the end 10:54, he mentions that versus IVM there are other perhaps more targeted to various pathways with natural phytochemical found in vegetables and fruits like Resveritrol (grape skins), Curcumin, EGCG (Green Tea), Quercetin (Apple skins
I thought this was interesting and recently was posted. At the end 10:54, he mentions that versus IVM there are other perhaps more targeted to various pathways with natural phytochemical found in vegetables and fruits like Resveritrol (grape skins), Curcumin, EGCG (Green Tea), Quercetin (Apple skins
Nwdx
in
Fight Prostate Cancer
3 months ago
Pluvicto Question
Hi Fellow Warriors! Six months of Taxotere failed miserably. After 8 rounds, I was done. After chemo, my second PSMA-PET showed additional bone mets and a spread to the lymph nodes. My MO told me I was a good candidate for Pluvicto, so, three months after finishing Taxotere, I started that therapy
Hi Fellow Warriors! Six months of Taxotere failed miserably. After 8 rounds, I was done. After chemo, my second PSMA-PET showed additional bone mets and a spread to the lymph nodes. My MO told me I was a good candidate for Pluvicto, so, three months after finishing Taxotere, I started that therapy
MJCA
in
Advanced Prostate Cancer
6 months ago
Diagnosed with Richters
My history is a CLL diagnosis around Sept of 2016. I started the Ibrutinib/Venetoclax trial at MDA in Jan 2017 achieving MRD U in April 2019. Clear sailing until April ‘22 when my blood test showed .07 CLL cells that doubled every 6 months. Showing no symptoms, my Doc did not recommend treatment.
My history is a CLL diagnosis around Sept of 2016. I started the Ibrutinib/Venetoclax trial at MDA in Jan 2017 achieving MRD U in April 2019. Clear sailing until April ‘22 when my blood test showed .07 CLL cells that doubled every 6 months. Showing no symptoms, my Doc did not recommend treatment.
Louie_CC
in
CLL Support
1 month ago
Dutasteride Reduces Tumor Volume by 30% after 6 months.
This chart compares prostate cancer tumor volume measured by MRI, at baseline and at 6 months, comparing placebo to Dutasteride. This was a randomized, double-blind, placebo-controlled clinical trial. The cohort included Low and Intermediate Risk men, GS-6-7, baseline PSA = 6-7, median age 64 y.o,
This chart compares prostate cancer tumor volume measured by MRI, at baseline and at 6 months, comparing placebo to Dutasteride. This was a randomized, double-blind, placebo-controlled clinical trial. The cohort included Low and Intermediate Risk men, GS-6-7, baseline PSA = 6-7, median age 64 y.o,
janebob99
in
Prostate Cancer Network
6 months ago
CGA and urogram
Hi All good advisers. Have been on pred for CGA since July 2023, starting at 60mg. now at 12 mg with very slow taper. I am having a kidney urogram this April. I am also on metformin 3 x daily 500 mg. I have read that I should stop taking metformin before this procedure. How many days before should
Hi All good advisers. Have been on pred for CGA since July 2023, starting at 60mg. now at 12 mg with very slow taper. I am having a kidney urogram this April. I am also on metformin 3 x daily 500 mg. I have read that I should stop taking metformin before this procedure. How many days before should
Groda
in
PMRGCAuk
6 months ago
Buscopan
Hello, all you lovely people in this group. Can you please advise if Buscopan or Mebeverine is better for stomach cramps. Many thanks
Hello, all you lovely people in this group. Can you please advise if Buscopan or Mebeverine is better for stomach cramps. Many thanks
Harley1020
in
IBS Network
3 months ago
Losartan potassium
I have been told I have CKD3 and that I should take losartan potassium for my blood pressure. I am a bit unhappy taking this as my weight seems to have increased after about 2-3 weeks and I have read that you should not take potassium if you have CKD3,
I have been told I have CKD3 and that I should take losartan potassium for my blood pressure. I am a bit unhappy taking this as my weight seems to have increased after about 2-3 weeks and I have read that you should not take potassium if you have CKD3,
Halifax11
in
Kidney Disease
1 year ago
Ashwagandha 1,000 mg
Hi everyone,I've been suffering from bad fatigue for months, as well as having prostate cancer last year, psa is good on last test, hot sweats reduced! I have purchased Ashwagandha from amazon, read lots of Google good and bads about it, but worried as quite a lot mentioned if on thyroid medication or
Hi everyone,I've been suffering from bad fatigue for months, as well as having prostate cancer last year, psa is good on last test, hot sweats reduced! I have purchased Ashwagandha from amazon, read lots of Google good and bads about it, but worried as quite a lot mentioned if on thyroid medication or
Tracy99
in
Thyroid UK
6 months ago
Terrible stomach pain with Adrenavive I
I swapped to Adrenavive I from Adrenavive II at the beginning of June. Since starting the new product I've found it gives me horrible stomach pains, last week to the point of vomiting. The pains eventually subside but it takes around 4-5 hours. I get these pains despite eating before taking the product
I swapped to Adrenavive I from Adrenavive II at the beginning of June. Since starting the new product I've found it gives me horrible stomach pains, last week to the point of vomiting. The pains eventually subside but it takes around 4-5 hours. I get these pains despite eating before taking the product
Jamima
in
Thyroid UK
3 months ago
Would I absorb B12 in tablet form if I had PA?
Hi all, On a hunt to figure out the cause of my continued iron loss... Had an iron infusion in July 2021 and I'm now back to deficiency. GP has done all they can, confirmed by private GP. The guidelines now assume iron loss is related to periods... except mine are very light and only last a day so
Hi all, On a hunt to figure out the cause of my continued iron loss... Had an iron infusion in July 2021 and I'm now back to deficiency. GP has done all they can, confirmed by private GP. The guidelines now assume iron loss is related to periods... except mine are very light and only last a day so
WitchingHour2point0
in
Pernicious Anaemia Society
3 months ago
Post Covid B12 and Vitamin D crash
Hi,I have had multiple health problems since my first bout of Covid in 2022, and blood panels revealed low B12, D and very low ferritin (11). I started having B12 injections and got my ferritin to 159 and my folate up to 45 from 5. I was feeling healthy and many of my symptoms had stopped. I had been
Hi,I have had multiple health problems since my first bout of Covid in 2022, and blood panels revealed low B12, D and very low ferritin (11). I started having B12 injections and got my ferritin to 159 and my folate up to 45 from 5. I was feeling healthy and many of my symptoms had stopped. I had been
Skater21
in
Pernicious Anaemia Society
3 months ago
Creating a Framework for Treating Autoimmune Gastritis—The Case for Replacing Lost Acid
A paper from Bruce Wolffenbuttel and colleagues, released last February https://www.mdpi.com/2072-6643/16/5/662 Conclusion: [i]"Autoimmune gastritis is not a gastritis that needs acid suppression; rather, it may benefit from acid supplementation. The loss of stomach acid in AIG precedes nutrient deficiencies
A paper from Bruce Wolffenbuttel and colleagues, released last February https://www.mdpi.com/2072-6643/16/5/662 Conclusion: [i]"Autoimmune gastritis is not a gastritis that needs acid suppression; rather, it may benefit from acid supplementation. The loss of stomach acid in AIG precedes nutrient deficiencies
Technoid
in
Pernicious Anaemia Society
3 months ago
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