Experiences with
Gallbladder and bile duct diseases81,036 public posts
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Tuesday's Tip
[i]PBC is long term in nature with bile duct injury typically occurring over the years. Many more patients die [/i][u][i]with[/i][/u][i] the disease - [/i][u][i]not[/i][/u][i] from it.[/i]
[i]It can cause injury in 2 ways: [/i]
[i]1. This is the progressive
Great news!
** ANNOUNCEMENT **
The Medicines & Healthcare Products Regulatory Agency (MHRA) in the UK have announced the approval of Seladelpar (Livdelzi) to be used in the treatment of adult patients in the UK with Primary Biliary Cholangitis.
This is exciting news as it provides an additional second line therapy
Tuesday's Tip
[i]Pain is frequently felt as a dull to severe sensation in the right upper quadrant of your abdomen. It can often be an indication of gallstones, especially after a fatty meal. PBC patients can suffer from these due to the fact that with PBC the flow of bile is already impeded to some degree. However
Tuesday's Tip
[i]Taking Urso can often cause some stomach issues - bloating or nausea. Being a bile salt, it can cause many people GI issues until your body adjusts to it.[/i]
[i]It's not always necessary to take your whole Urso dose right from the beginning. According to Dr. Jones, he often tells people
Wednesday's Word
[u][i]Bile[/i][/u]
Bile is the drainage fluid from the liver. Hepatocytes make it and then is modified by the cells of the bile duct.
It has 2 main functions:
1. It helps facilitate the byproducts produced by our liver functioning.
2. It helps transport the bile acids to our bowel, where
Tuesday's Tip
[u][i]Alkaline phosphatase [/i][/u]
It is an enzyme released as a response to injury to the bile ducts - not the liver itself. As more cells are injured, the more alk phos is released. Alk phos is not in itself harmful. Higher levels in the blood does not mean more tissue damage. Even lowering
Tuesday's Tip
Most of us have had a + AMA blood test somewhere along the way to a diagnosis. Some of us find that our AMA test results have elevated and should we be concerned. In short, no, says Dr. Jones. He feels a + (positive) AMA does not necessarily play any part in actually causing the disease.
Wednesday's Word
[u][i]MRCP [/i][/u]-
This is a type of body scan that examines the bile ducts in great detail, using a magnetic resonance imaging (MRI).
It looks for any blockage in the bile ducts or the presence of any gallstones.
Previously the ERCP was used to achieve this examination. It required, however