Experiences with
Gallbladder and bile duct diseases79,750 public posts
Wednesday's Word
[u][i]Bile[/i][/u]
Bile is the drainage fluid from the liver. Hepatocytes make it and then is modified by the cells of the bile duct.
It has 2 main functions:
1. It helps facilitate the byproducts produced by our liver functioning.
2. It helps transport the bile acids to our bowel, where
Tuesday's Tip
[u][i]Alkaline phosphatase [/i][/u]
It is an enzyme released as a response to injury to the bile ducts - not the liver itself. As more cells are injured, the more alk phos is released. Alk phos is not in itself harmful. Higher levels in the blood does not mean more tissue damage. Even lowering
Want to take advantage of all our features? Just log in!
or
Tuesday's Tip
Most of us have had a + AMA blood test somewhere along the way to a diagnosis. Some of us find that our AMA test results have elevated and should we be concerned. In short, no, says Dr. Jones. He feels a + (positive) AMA does not necessarily play any part in actually causing the disease.
Wednesday's Word
[u][i]MRCP [/i][/u]-
This is a type of body scan that examines the bile ducts in great detail, using a magnetic resonance imaging (MRI).
It looks for any blockage in the bile ducts or the presence of any gallstones.
Previously the ERCP was used to achieve this examination. It required, however
Wednesday's Word
[u][i]Alkaline Transaminase (ALT)[/i][/u]
This is a blood test that is part of our liver panel. It is released predominantly by injured hepatocytes (cells of the liver), making it usually more prone to be seen in hepatitis. PBC is primarily a disease of the bile duct cells (biliary
Tuesday's Tip
[i]For the most part physicians have given Urso up to a year to decide if you are a responder or not -- has the Urso decreased your numbers significantly in that time period.[/i]
[i]According to Dr. Jones (world 's leading expert on PBC) the thinking may soon be that only a 6 month period
Info on Golexanolone
May 23, 2024MenuSECTIONS
Golexanolone Phase 2 Trial for PBC Begins With First Patient Randomizations
Avatar photoJuliana Campos, PhD | May 23, 2024
Umecrine Cognition has announced the randomization of the first 2 patients into the second part of its ongoing phase 1b/2 clinical study of golexanolone