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TRAP trial: radiotherapy combined with hormone therapy can help some advanced prostate cancer patients avoid chemotherapy
TRAP is maybe not the best name for a clinical trial, but hey… https://www.icr.ac.uk/news-archive/new-trial-finds-radiotherapy-combined-with-hormone-therapy-can-help-some-advanced-prostate-cancer-patients-avoid-chemotherapy
TRAP is maybe not the best name for a clinical trial, but hey… https://www.icr.ac.uk/news-archive/new-trial-finds-radiotherapy-combined-with-hormone-therapy-can-help-some-advanced-prostate-cancer-patients-avoid-chemotherapy
Maxone73
in
Advanced Prostate Cancer
3 months ago
A-Dream iADT Protocol
It has been awhile since my last post. Short story is I responded well to the doublet therapy in Arasec (lupron+daro). MO believes there is some chance my M1B diagnosis at the start was incorrect (he refers to my case as 'discordant' - due to conflicting data - Gleason 6 but some spots lit up on
It has been awhile since my last post. Short story is I responded well to the doublet therapy in Arasec (lupron+daro). MO believes there is some chance my M1B diagnosis at the start was incorrect (he refers to my case as 'discordant' - due to conflicting data - Gleason 6 but some spots lit up on
Heykm01
in
Advanced Prostate Cancer
3 months ago
Exercise making it worse?
Hi everyone, I have a question about exercise and endo. So basically I've been pretty much bedbound all of last year with rare weeks of being able to function, but lately I've experience a good couple of months of feeling better and being able to live! (Don't get me wrong still in pain but manageable
Hi everyone, I have a question about exercise and endo. So basically I've been pretty much bedbound all of last year with rare weeks of being able to function, but lately I've experience a good couple of months of feeling better and being able to live! (Don't get me wrong still in pain but manageable
Lavenderpetal
in
Endometriosis UK
7 months ago
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Celebrex and Curcumin and Magnesium.
I recently received a question from a fellow warrior based on a comment I had made on an older post that he had started. The question was what I thought about Naproxen compered to Celebrex and I told him I had very limited experience with Naproxen. I then clicked on older posts about nsaids and prostate
I recently received a question from a fellow warrior based on a comment I had made on an older post that he had started. The question was what I thought about Naproxen compered to Celebrex and I told him I had very limited experience with Naproxen. I then clicked on older posts about nsaids and prostate
Professorgary
in
Advanced Prostate Cancer
3 months ago
GnRH analogues
Hi all, I am due to be starting injectable GnRH analogues soon alongside a HRT, dose anyone have any advice/ guidance on them and their side effects and management? In the past I have had Nafarelin (Synarel). The plan is to have these before surgery as NHS wait is 50 weeks where I am. Thanks
Hi all, I am due to be starting injectable GnRH analogues soon alongside a HRT, dose anyone have any advice/ guidance on them and their side effects and management? In the past I have had Nafarelin (Synarel). The plan is to have these before surgery as NHS wait is 50 weeks where I am. Thanks
Foodman500
in
Endometriosis UK
1 year ago
"Gasoline" Source
I have been trying to find the source for the observation? that "Testosterone to prostate cancer is like gasoline on a fire". I finally asked Bing Copilot and ChatGPT-- who came up with the answer. Me: What is the source of the "gasoline on a fire" theory in prostate cancer? ChatGPT: Dr. Patrick
I have been trying to find the source for the observation? that "Testosterone to prostate cancer is like gasoline on a fire". I finally asked Bing Copilot and ChatGPT-- who came up with the answer. Me: What is the source of the "gasoline on a fire" theory in prostate cancer? ChatGPT: Dr. Patrick
VoxHope
in
Advanced Prostate Cancer
3 months ago
knee surgery discussion with orthopedic surgeon
Hello out there, I would like to get some feedback from people who have had knee surgery that have RA. My last surgery (bladder mesh removal) meant I had no RA drugs in me for a month and it was brutal, trying to heal and being in a big flare from the trauma on my body. Any tips or words of wisdom
Hello out there, I would like to get some feedback from people who have had knee surgery that have RA. My last surgery (bladder mesh removal) meant I had no RA drugs in me for a month and it was brutal, trying to heal and being in a big flare from the trauma on my body. Any tips or words of wisdom
lala1958
in
FieryBones - RA Community
11 months ago
What comes after, what comes next?
I have posted a few times about my dad. Stage 4, mets to 8+ bones at time of diagnosis, PSA at 137 (10/22.) Lupron twice a year, Bicalutamide, failed at 7 months, Xtandi failed at 4 months, currently on Zytiga. We met with my dad’s oncologist on 4/24. My Dad’s PSA dropped from 2.47-1.46 and pain has
I have posted a few times about my dad. Stage 4, mets to 8+ bones at time of diagnosis, PSA at 137 (10/22.) Lupron twice a year, Bicalutamide, failed at 7 months, Xtandi failed at 4 months, currently on Zytiga. We met with my dad’s oncologist on 4/24. My Dad’s PSA dropped from 2.47-1.46 and pain has
lgutman
in
Advanced Prostate Cancer
3 months ago
ADT + Docetaxel
Am mCRPC and will be starting Docetaxel soon, after apparent failure of Zytiga. Would like to know if I should continue the ADT (zoladex), which I have tolerated well for 3 years. Most trial info I have found (STAMPEDE, CHAARTED) tests ADT alone vs ADT + Docetaxel, where the combination outcome is
Am mCRPC and will be starting Docetaxel soon, after apparent failure of Zytiga. Would like to know if I should continue the ADT (zoladex), which I have tolerated well for 3 years. Most trial info I have found (STAMPEDE, CHAARTED) tests ADT alone vs ADT + Docetaxel, where the combination outcome is
Ian99
in
Advanced Prostate Cancer
3 months ago
ADT & Pluvicto
Is it common to continue ADT treatments, like Lupron or Eligard, while receiving Pluvicto therapy?
Is it common to continue ADT treatments, like Lupron or Eligard, while receiving Pluvicto therapy?
Shams_Vjean
in
Advanced Prostate Cancer
3 months ago
Can people with hypothyroidism suffer with sweats and heat intolerance?
Before I was diagnosed with hypothyroidism and put on medication, I suffered with dreadful sweating for years; eating hot food or drinks would being it on as would housework and sitting in a stuffy office environment. This would be the type that would soak on hair and clothing. For a long time I thought
Before I was diagnosed with hypothyroidism and put on medication, I suffered with dreadful sweating for years; eating hot food or drinks would being it on as would housework and sitting in a stuffy office environment. This would be the type that would soak on hair and clothing. For a long time I thought
Upanddownlady15
in
Thyroid UK
1 year ago
hope for negative 11dp3dt to turn positive by OTD?
Tested 3 days early for a day 3 FET (day 11, past transfer but worked out this would have been day 14 if I’d conceived naturally) on second urine of day and got a negative. Is this the end of the road or has anyone had this and still gone on to test positive? I’ve fallen apart today and not in great
Tested 3 days early for a day 3 FET (day 11, past transfer but worked out this would have been day 14 if I’d conceived naturally) on second urine of day and got a negative. Is this the end of the road or has anyone had this and still gone on to test positive? I’ve fallen apart today and not in great
ForABabyPanda
in
Fertility Network UK
1 year ago
Salvage options?
Hello again, I have a few more questions, to help my husband decide between surgery and brachyboost. For context, he is localized Gleason 9. (1) Is the course of salvage radiation after RP typically the same as it would have been if the initial treatment had been radiation therapy? Or would it require
Hello again, I have a few more questions, to help my husband decide between surgery and brachyboost. For context, he is localized Gleason 9. (1) Is the course of salvage radiation after RP typically the same as it would have been if the initial treatment had been radiation therapy? Or would it require
EvFC
in
Advanced Prostate Cancer
4 months ago
If you are thinking of Travel - Go For It.
Hello everyone, We're midway through our 10-week holiday adventure, and it's been quite a journey so far! From Japan to Finland, Turkey, and now Italy, we've covered quite a bit of ground. Traveling alongside another couple, our time in Turkey stands out, where I took on the role of designated driver
Hello everyone, We're midway through our 10-week holiday adventure, and it's been quite a journey so far! From Japan to Finland, Turkey, and now Italy, we've covered quite a bit of ground. Traveling alongside another couple, our time in Turkey stands out, where I took on the role of designated driver
Mike58
in
Prostate Cancer Network
4 months ago
Why is this so hard, someone to talk to
Hi everyone. I had treatment resistant depression for my entire adult life, I've been on pretty much every med, hospitalized, ECT tms and ketamine. Nothings helped. I've gone the DBT and cbt route. I've been suicidal. Can anyone out there relate? I'm married with a 13 year old which makes it harder.
Hi everyone. I had treatment resistant depression for my entire adult life, I've been on pretty much every med, hospitalized, ECT tms and ketamine. Nothings helped. I've gone the DBT and cbt route. I've been suicidal. Can anyone out there relate? I'm married with a 13 year old which makes it harder.
Coffeeshop
in
Anxiety and Depression Support
7 months ago
Guess what? Your body has changed and will never be the same.
I recently read a post from a guy that stated he had muscle and stamina loss. The post and responses then went on in a very hand wringing way to ask and discuss things like, “should I eat whey”, “what about protein and in what form”, “I never eat or drink dairy products”. It then went on to lament all
I recently read a post from a guy that stated he had muscle and stamina loss. The post and responses then went on in a very hand wringing way to ask and discuss things like, “should I eat whey”, “what about protein and in what form”, “I never eat or drink dairy products”. It then went on to lament all
OldGuysRule
in
Advanced Prostate Cancer
4 months ago
Private dexa scan
Hi all, I am 37 and been perimenopausal for well over a year. My mother has arthritic hips and knees which resulted in a double hip replacement a decade ago. Is it worth getting a dexa scan now? If it is; is there anywhere in the South West I can get one done privately?
Hi all, I am 37 and been perimenopausal for well over a year. My mother has arthritic hips and knees which resulted in a double hip replacement a decade ago. Is it worth getting a dexa scan now? If it is; is there anywhere in the South West I can get one done privately?
WitchingHour2point0
in
Thyroid UK
11 months ago
To those who have read Dr Richard Wassersug's book....
As mentioned in other posts, off Erleada as it's contraindicated in my treatment of Multiple Myeloma. I was just approved for Zytiga. Hurray for me. Anyway, I have not read his book yet but it's on my list. I recently watched his Tube Video and found it interesting but covered other higher priority
As mentioned in other posts, off Erleada as it's contraindicated in my treatment of Multiple Myeloma. I was just approved for Zytiga. Hurray for me. Anyway, I have not read his book yet but it's on my list. I recently watched his Tube Video and found it interesting but covered other higher priority
swwags
in
Advanced Prostate Cancer
10 months ago
Long complicated paper on gut microbiome and PCa, human and mouse studies.
The gut microbiome-prostate cancer crosstalk is modulated by dietary polyunsaturated long-chain fatty acids Nature Communications volume 15, Article number: 3431 (2024) PMID: 38654015 PMCID: PMC11039720 DOI: 10.1038/s41467-024-45332-w Some snippets from the paper: ”Hypercaloric diets, such as
The gut microbiome-prostate cancer crosstalk is modulated by dietary polyunsaturated long-chain fatty acids Nature Communications volume 15, Article number: 3431 (2024) PMID: 38654015 PMCID: PMC11039720 DOI: 10.1038/s41467-024-45332-w Some snippets from the paper: ”Hypercaloric diets, such as
Graham49
in
Advanced Prostate Cancer
4 months ago
Any advice welcome on latest blood tests
I've been tinkering around with Hydrocortisone and thyroid replacement for over a year now and been symptomatic for almost 4 years with low tsh and frees. I recently stopped all thyroid and HC and felt awful after around a month, so asked my GP for help (big mistake). They only do email consults and
I've been tinkering around with Hydrocortisone and thyroid replacement for over a year now and been symptomatic for almost 4 years with low tsh and frees. I recently stopped all thyroid and HC and felt awful after around a month, so asked my GP for help (big mistake). They only do email consults and
Jamima
in
Thyroid UK
1 year ago
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