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Update on trametinib (Mekinist) for low grade serous ovarian cancer
Good morning everyone We are delighted that NHS England has recommended that the MEK-inhibitor trametinib (Mekinist) should be routinely available as an off-label treatment option for adults with recurrent or progressive low grade serous ovarian cancer (LGSOC). This is for people who have received
Good morning everyone We are delighted that NHS England has recommended that the MEK-inhibitor trametinib (Mekinist) should be routinely available as an off-label treatment option for adults with recurrent or progressive low grade serous ovarian cancer (LGSOC). This is for people who have received
OvacomeSupport
My Ovacome Team
in
My Ovacome
6 months ago
Coming off HRT patches
Hi everyone, I'm 55 years old and I've been on a bit of a health journey these last few years to say the least, with many debilitating symptoms including crushing fatigue. As part of the treatment for this, I went onto HRT oestrogen patches 18 months ago, along with the mirena coil I already had.
Hi everyone, I'm 55 years old and I've been on a bit of a health journey these last few years to say the least, with many debilitating symptoms including crushing fatigue. As part of the treatment for this, I went onto HRT oestrogen patches 18 months ago, along with the mirena coil I already had.
KBird01
in
Menopause and Perimenopause Support
11 months ago
Prostap and Tibolone HRT. Any advice please?
I have recently started the Prostap injection whilst I am waiting for my second endo surgery. I have have two injections and I am on tibolone to help with symptoms. I am having hot sweats, headaches, severe fatigue and feeling achy. I also feel hungry but then when I go to eat something it makes me
I have recently started the Prostap injection whilst I am waiting for my second endo surgery. I have have two injections and I am on tibolone to help with symptoms. I am having hot sweats, headaches, severe fatigue and feeling achy. I also feel hungry but then when I go to eat something it makes me
Em_wilkinson96
in
Endometriosis UK
11 months ago
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Prostap and Hrt
Good morning all. I was on prostap for over 2 years and have been on that combined with hrt for about 18 months while i await a lap which I have booked on 6th July. I had a bone density scan in January and have just received a letter from my consultant. They have said I must stop the prostap immediately
Good morning all. I was on prostap for over 2 years and have been on that combined with hrt for about 18 months while i await a lap which I have booked on 6th July. I had a bone density scan in January and have just received a letter from my consultant. They have said I must stop the prostap immediately
Mustang2598
in
Endometriosis UK
11 months ago
Feeling abandoned by Hospital - Advice?
Hey all, I am at a loss at the moment. I have Endo, adenomyosis and colitis. I have had 3 laps and on various medication. January 2022, my treatment has been moved from Gynea to Pelvic Pain Management and I was put onto the Zoladex injection and HRT - for 6 months..... however it never stopped
Hey all, I am at a loss at the moment. I have Endo, adenomyosis and colitis. I have had 3 laps and on various medication. January 2022, my treatment has been moved from Gynea to Pelvic Pain Management and I was put onto the Zoladex injection and HRT - for 6 months..... however it never stopped
_Noo_
in
Endometriosis UK
11 months ago
Total knee replacement - 6 weeks on
Hi Today is my 6 week anniversary of having my TKR on my right knee. I'm keen to start driving again and wondered if I need to get the go ahead from the physio first or what is the protocol? My understanding was that if you can do an emergency stop you can drive. I have an automatic car so I'll be
Hi Today is my 6 week anniversary of having my TKR on my right knee. I'm keen to start driving again and wondered if I need to get the go ahead from the physio first or what is the protocol? My understanding was that if you can do an emergency stop you can drive. I have an automatic car so I'll be
Divasong
in
Arthritis Action
5 months ago
Depression sucks
I have been struggling for two year. In the last two years I have been hospitalized 5 times. I found that ECT/shock therapy, is the only thing that helps. So I started about a month ago feeling better and the depression was lifting. So I changed my ECT to every other week and it was going well, however
I have been struggling for two year. In the last two years I have been hospitalized 5 times. I found that ECT/shock therapy, is the only thing that helps. So I started about a month ago feeling better and the depression was lifting. So I changed my ECT to every other week and it was going well, however
sunshinefan
in
Anxiety and Depression Support
3 days ago
Advice please x
Hey everyone, I’ve been suffering with anxiety specifically social anxiety for over 6 years now. I’ve tried every medication, herbal, magic drink, exercising weekly, counselling, hypnotherapy ect everything you can think of I’ve tried and honestly nothing seems to of helped. When I went on sertraline
Hey everyone, I’ve been suffering with anxiety specifically social anxiety for over 6 years now. I’ve tried every medication, herbal, magic drink, exercising weekly, counselling, hypnotherapy ect everything you can think of I’ve tried and honestly nothing seems to of helped. When I went on sertraline
Gymlover1234
in
Anxiety and Depression Support
4 days ago
My Anxiety
Hi I am Natalie, I have suffered from Anxiety also depression from the age of 21, 27 years of my life. I find that my anxiety gets really bad when I have to deal with issues like bills, meetings ect. Luckily I have Two Sons, my eldest Son helps me with all bills. The very first time I took a anxiety
Hi I am Natalie, I have suffered from Anxiety also depression from the age of 21, 27 years of my life. I find that my anxiety gets really bad when I have to deal with issues like bills, meetings ect. Luckily I have Two Sons, my eldest Son helps me with all bills. The very first time I took a anxiety
natalieZza
in
Anxiety and Depression Support
6 days ago
Covid jabs
I'm curious to know if anyone in the group has noticed dramatic changes in there condition since taking the jabs ? I never wanted one and had two plus a booster and a couple of years later I was falling apart with many complications. I have had chiroses for 37 years plus gallstones and went through a
I'm curious to know if anyone in the group has noticed dramatic changes in there condition since taking the jabs ? I never wanted one and had two plus a booster and a couple of years later I was falling apart with many complications. I have had chiroses for 37 years plus gallstones and went through a
Trust78
in
British Liver Trust
11 days ago
New 2024 AUA/ASTRO/SUO Guidelines for Salvage Therapy
https://www.auanet.org/guidelines-and-quality/guidelines/salvage-therapy-for-prostate-cancer Not surprising. I think they should recommend adjuvant ADT at a PSA≥0.35 instead of ≥0.7 because I think patients are hoping for curative SRT and not just equivalent survival. https://www.prostatecancer.news
https://www.auanet.org/guidelines-and-quality/guidelines/salvage-therapy-for-prostate-cancer Not surprising. I think they should recommend adjuvant ADT at a PSA≥0.35 instead of ≥0.7 because I think patients are hoping for curative SRT and not just equivalent survival. https://www.prostatecancer.news
Tall_Allen
in
Advanced Prostate Cancer
3 months ago
Learn CPR and Defibrillator training
More people need CPR training. Not enough people do. I am an ex Nurse and Firefighter and seen first hand the benefits of learning CPR ect. I now have my First Aid Instructor qualification and teach Basic Life Support-CPR-Defibrillator training. My own training has helped me in 2 different situations
More people need CPR training. Not enough people do. I am an ex Nurse and Firefighter and seen first hand the benefits of learning CPR ect. I now have my First Aid Instructor qualification and teach Basic Life Support-CPR-Defibrillator training. My own training has helped me in 2 different situations
Nevharris
in
British Heart Foundation
15 days ago
Ocaliva
Hi everybody, I’ve just been told that I should now start ocaliva aswell as urso I’m so worried about side effects after reading up on it, wondering how many of youse are getting on with it did you have lots of side effects ect!!
Hi everybody, I’ve just been told that I should now start ocaliva aswell as urso I’m so worried about side effects after reading up on it, wondering how many of youse are getting on with it did you have lots of side effects ect!!
Lena2011
in
PBC Foundation
15 days ago
Post Menopausal Fibroids
I am 62 and have been diagnosed with fibroids as a result of CT and US scans. Pelvic pain is constant, often severe. My HRT has been switched to Tibolone which I am told will not ‘feed’ the fibroids. I am waiting for an NHS gynae referral appointment which will not be anytime soon as there is a huge
I am 62 and have been diagnosed with fibroids as a result of CT and US scans. Pelvic pain is constant, often severe. My HRT has been switched to Tibolone which I am told will not ‘feed’ the fibroids. I am waiting for an NHS gynae referral appointment which will not be anytime soon as there is a huge
Juno09
in
Women's Health
11 months ago
Categorize Differences ?
I have said before, my first neurologist , a world recognized doctor in the field of PD told me 20 years ago that someday what we now know as Parkinson's Disease will be 10 to 15 or more individual diseases that resemble each other but may be treated differently. I keep forgetting this and continue
I have said before, my first neurologist , a world recognized doctor in the field of PD told me 20 years ago that someday what we now know as Parkinson's Disease will be 10 to 15 or more individual diseases that resemble each other but may be treated differently. I keep forgetting this and continue
Gymsack
in
Cure Parkinson's
17 days ago
norethisterone to delay period
hi everyone! does anyone have experience with norethisterone to delay period for holidays ect? I have never used it but i have a holiday coming up that the pain of being on my period would completely ruin. For me, delaying the period pain is a main priority. Any advice or experiences would be really
hi everyone! does anyone have experience with norethisterone to delay period for holidays ect? I have never used it but i have a holiday coming up that the pain of being on my period would completely ruin. For me, delaying the period pain is a main priority. Any advice or experiences would be really
Bk27
in
Endometriosis UK
18 days ago
I'm Back....
Hi Everyone, I was on this site several months ago and since then have been in a psychiatric hospital, been seeing a psychiatrist, had EMDR and ketamine treatments, had weekly therapy sessions and am about to try a new therapist, and have tried five different anti-depressants. I'm still struggling
Hi Everyone, I was on this site several months ago and since then have been in a psychiatric hospital, been seeing a psychiatrist, had EMDR and ketamine treatments, had weekly therapy sessions and am about to try a new therapist, and have tried five different anti-depressants. I'm still struggling
Woolybluecurl
in
Anxiety and Depression Support
20 days ago
Prostate Cancer Diet and Re-purposed Meds
I was just reading a post about Jane Mcclelland's protocol regarding her book, "How to starve cancer." She also added a second portion on a book re-released, with a Ferroptosis (death by iron) protocol. I thought the criticism to be amazing. Cancer is a baffling mystery, top scientist and great minds
I was just reading a post about Jane Mcclelland's protocol regarding her book, "How to starve cancer." She also added a second portion on a book re-released, with a Ferroptosis (death by iron) protocol. I thought the criticism to be amazing. Cancer is a baffling mystery, top scientist and great minds
PlantrichyRich
in
Advanced Prostate Cancer
20 days ago
Chiropractors
Sometimes I comment on chiropractors and how they can affect health issues. I posted this on another post and thought maybe some people, who do not read that post, could be interested. There is a chance that the condition of the spine could have something to do with AF. Heart doctors generally do not
Sometimes I comment on chiropractors and how they can affect health issues. I posted this on another post and thought maybe some people, who do not read that post, could be interested. There is a chance that the condition of the spine could have something to do with AF. Heart doctors generally do not
EngMac
in
AF Association
6 months ago
Help!
Hello, everyone, I've an appointment to see my doctor tomorrow and would like to know what strength of buprenorphine helps rls? I'm not doing so good, rls back with a vengeance, had to go back on the hrt gel as I found my rls was way worse after stopping it, I'm crawling all over, day and night since
Hello, everyone, I've an appointment to see my doctor tomorrow and would like to know what strength of buprenorphine helps rls? I'm not doing so good, rls back with a vengeance, had to go back on the hrt gel as I found my rls was way worse after stopping it, I'm crawling all over, day and night since
Loopylegs
in
Restless Legs Syndrome
11 months ago
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