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Estradiol / Dienogest
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Constipation is a known issue with the Orgovyx
I've been on Orgovyx (Relugolix) for around 2.5 years now. and find myself getting increasingly constipated. It's the most tenacious SE. My labs are all stable and my PSA is stable at <0.02. But I'm now on 4 types of laxatives and next am planning on getting an enema and trying that. I have an appt with
I've been on Orgovyx (Relugolix) for around 2.5 years now. and find myself getting increasingly constipated. It's the most tenacious SE. My labs are all stable and my PSA is stable at <0.02. But I'm now on 4 types of laxatives and next am planning on getting an enema and trying that. I have an appt with
NewPotatoCaboose
in
Advanced Prostate Cancer
4 months ago
Dienogest and fatigue
Hello everyone, Has anyone experienced intense fatigue while on Dienogest? Thank you, Audrey
Hello everyone, Has anyone experienced intense fatigue while on Dienogest? Thank you, Audrey
Audrey4
in
Endometriosis UK
9 months ago
Perplexed over lab work
Hello, I am a 32 y/o white female. Some history about me that may be applicable: Surgeries: Gallbladder removed (2011), Gastric Sleeve (2017) Weight loss surgery: Started at 332lbs, currently fluctuate between 178-185. Diagnoses: Major Depressive Disorder, GERD (resulting from WLS), ADHD, Anemia
Hello, I am a 32 y/o white female. Some history about me that may be applicable: Surgeries: Gallbladder removed (2011), Gastric Sleeve (2017) Weight loss surgery: Started at 332lbs, currently fluctuate between 178-185. Diagnoses: Major Depressive Disorder, GERD (resulting from WLS), ADHD, Anemia
aybaylay
in
Pernicious Anaemia Society
4 months ago
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Could I be harming my heart & vascular system with my consistently high BP, despite being on lots of cardiac and BP meds?
Despite being on the following list of meds I'm still getting BP spikes, with my weekly average being in the high 140's/80's and I'm getting angina, with related symptoms, weekly (although less intense since being on isosorbide mononitrate). I've been taking my BP for almost a year now and so I know
Despite being on the following list of meds I'm still getting BP spikes, with my weekly average being in the high 140's/80's and I'm getting angina, with related symptoms, weekly (although less intense since being on isosorbide mononitrate). I've been taking my BP for almost a year now and so I know
bee_bear
in
British Heart Foundation
5 months ago
Location of Estrogen Patches matters.
These plots compare applying estrogen patches to a forearm or to the scrotum. Overall, the average serum estradiol concentration is
3-4 times
higher for scrotal application, compared to forearm application. This is particularly relevant to estrogen users who use gel, cream, or spray products
These plots compare applying estrogen patches to a forearm or to the scrotum. Overall, the average serum estradiol concentration is
3-4 times
higher for scrotal application, compared to forearm application. This is particularly relevant to estrogen users who use gel, cream, or spray products
janebob99
in
Prostate Cancer Network
5 months ago
How to convince a GP to prescribe estradiol patches?
I've been busy with ADT for almost 5 years and one of the most insidious SE has always been hot flushes. I find them quite debilitating as, when they hit (and that's often), I'm briefly incapable to concentrate/perform any task. After reading about some of you guys experiences with estradiol patches
I've been busy with ADT for almost 5 years and one of the most insidious SE has always been hot flushes. I find them quite debilitating as, when they hit (and that's often), I'm briefly incapable to concentrate/perform any task. After reading about some of you guys experiences with estradiol patches
R1166
in
Advanced Prostate Cancer
5 months ago
Suspected Endometriosis advice
This is my first post and was wondering if anyone could give any advice. I've been struggled with my cycle for years now and keept visiting the gyno. After all this time the word Endometriosis was used on my notes when i was having a scan. I've lost count how many pills i've been on to try and help my
This is my first post and was wondering if anyone could give any advice. I've been struggled with my cycle for years now and keept visiting the gyno. After all this time the word Endometriosis was used on my notes when i was having a scan. I've lost count how many pills i've been on to try and help my
painhater88
in
Endometriosis UK
9 months ago
Dienogest 2mg
I've recently been prescribed dienogest, and have been taking it for the last 4 days. I'm looking to see what others experiences were of this medication, whether it helped, what the side effects were for you, how long the side effects took to start after starting the medication etc. I've declined to
I've recently been prescribed dienogest, and have been taking it for the last 4 days. I'm looking to see what others experiences were of this medication, whether it helped, what the side effects were for you, how long the side effects took to start after starting the medication etc. I've declined to
CeeCeeB10
in
Endometriosis UK
9 months ago
How many estrogen patches should I use?
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
janebob99
in
Advanced Prostate Cancer
5 months ago
How many estrogen patches to use?
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
I had a nice breakthrough today. 😀 I collected all of the available data on the number of estrogen patches that the studies have used, and plotted the measured serum estradiol level versus total milligrams of estrogen used every week. I was pleasantly surprised when all five of the data points
janebob99
in
Prostate Cancer Network
5 months ago
How many Estrogen Patches to use?
Here's a plot of the Estradiol serum concentration (pg/mL) as a function of total dose (micrograms) of estrogen patches over 1 week. The plot tells the number of patches and how often to change them. The three data points fall nicely on a straight line, which makes good sense. The PATCH study used
Here's a plot of the Estradiol serum concentration (pg/mL) as a function of total dose (micrograms) of estrogen patches over 1 week. The plot tells the number of patches and how often to change them. The three data points fall nicely on a straight line, which makes good sense. The PATCH study used
janebob99
in
Prostate Cancer Network
5 months ago
Looking for Estrogen users...
Hello, I'm doing a survey of estrogen users. I'd like to find out: 1. How many patches or gel pumps do you use a day, or a week? And what dose of E2 patches do you use? 2. What's your PSA? 3. What's your estradiol? 4. What's your testosterone? 5. What's your DHT (if you measure it)? 6. How
Hello, I'm doing a survey of estrogen users. I'd like to find out: 1. How many patches or gel pumps do you use a day, or a week? And what dose of E2 patches do you use? 2. What's your PSA? 3. What's your estradiol? 4. What's your testosterone? 5. What's your DHT (if you measure it)? 6. How
janebob99
in
Prostate Cancer Network
6 months ago
Looking for Estrogen Users...
Hello, I'm doing a survey of estrogen users. I'd like to find out: 1. How many patches or gel pumps do you use a day, or a week? And what dose of E2 patches do you use? 2. What's your PSA? 3. What's your estradiol? 4. What's your testosterone? 5. What's your DHT (if you measure it)? 6. How
Hello, I'm doing a survey of estrogen users. I'd like to find out: 1. How many patches or gel pumps do you use a day, or a week? And what dose of E2 patches do you use? 2. What's your PSA? 3. What's your estradiol? 4. What's your testosterone? 5. What's your DHT (if you measure it)? 6. How
janebob99
in
Advanced Prostate Cancer
6 months ago
My own PSA values over time: 70% drop in just 3 months on Dutasteride and no ADT
Here are my own PSA values versus time plot. You can see there is an exponential rise in PSA starting at around 6/1/23, and doubling from PSA = 5 to 10 in about 8 months. My MRI at PSA = 10 showed a T3a tumor about 1.3 cm long (PIRADS 5). A subsequent targeted biopsy showed Gleason 3+4 in 4 cores,
Here are my own PSA values versus time plot. You can see there is an exponential rise in PSA starting at around 6/1/23, and doubling from PSA = 5 to 10 in about 8 months. My MRI at PSA = 10 showed a T3a tumor about 1.3 cm long (PIRADS 5). A subsequent targeted biopsy showed Gleason 3+4 in 4 cores,
janebob99
in
Prostate Cancer Network
6 months ago
help with bloods.
I have been on HRT for 5 years. I'm currently on 300mg Utrogestan (100mg to 200mg 17/10 then 200mg 25 on 3 days off then up to 300mg on 11/2/24 25 days on 3 days off) and 100 evorel patch plus 1 pump of tostran gel twice a week. I have been having bleeds since June 23 (had an internal scan and biopsy
I have been on HRT for 5 years. I'm currently on 300mg Utrogestan (100mg to 200mg 17/10 then 200mg 25 on 3 days off then up to 300mg on 11/2/24 25 days on 3 days off) and 100 evorel patch plus 1 pump of tostran gel twice a week. I have been having bleeds since June 23 (had an internal scan and biopsy
WendyW1964
in
Menopause and Perimenopause Support
6 months ago
PCOS HASHIMOTOS FBC RESULTS ADVICE NEEDED
Hello,I'm a 26 years old woman with two young children aged 2 and 3. I've had Hashitmotos disease since 2017 and suffered from postpartum thyroiditis after both pregnancys. I also suffer eith PCOS for over 10 years. I've recently come off the contraceptive pill (progesterone only) I was only on it
Hello,I'm a 26 years old woman with two young children aged 2 and 3. I've had Hashitmotos disease since 2017 and suffered from postpartum thyroiditis after both pregnancys. I also suffer eith PCOS for over 10 years. I've recently come off the contraceptive pill (progesterone only) I was only on it
Serendipity97
in
PCOS UK (Verity)
6 months ago
Help and advice needed (PCOS, hashimotos, blood results)
Hello,I'm a 26 years old woman with two young children aged 2 and 3. I've had Hashitmotos disease since 2017 and suffered from postpartum thyroiditis after both pregnancys. I also suffer eith PCOS for over 10 years. I've recently come off the contraceptive pill (progesterone only) I was only on it
Hello,I'm a 26 years old woman with two young children aged 2 and 3. I've had Hashitmotos disease since 2017 and suffered from postpartum thyroiditis after both pregnancys. I also suffer eith PCOS for over 10 years. I've recently come off the contraceptive pill (progesterone only) I was only on it
Serendipity97
in
Thyroid UK
6 months ago
male hormones
Hi Ladies and Gents I wanted to ask if anyone knows where I can find a group/expert about male hormones? It’s for my husband, he has no thyroid issues, it’s about other hormones. He did a Randox test and it turns out he has elevated FSH, LH, Prolactin and Oestradiol. His Testosterone is ok, he is
Hi Ladies and Gents I wanted to ask if anyone knows where I can find a group/expert about male hormones? It’s for my husband, he has no thyroid issues, it’s about other hormones. He did a Randox test and it turns out he has elevated FSH, LH, Prolactin and Oestradiol. His Testosterone is ok, he is
Amazon07
in
Thyroid UK
6 months ago
Patches (I'm depending on you, son)
Dated pop reference - sorry. While my research has continued, my oncologist has nothing to give me within the SOC to keep the PSA in check. Now I've witnessed another unwelcome visitor: facial hair (it only took me 70 yrs to start shaving....) Joking aside however, that means the T is on the rise.
Dated pop reference - sorry. While my research has continued, my oncologist has nothing to give me within the SOC to keep the PSA in check. Now I've witnessed another unwelcome visitor: facial hair (it only took me 70 yrs to start shaving....) Joking aside however, that means the T is on the rise.
CrocodileShoes
in
Advanced Prostate Cancer
6 months ago
Estradiol, QoL and inflammation
Although I have been following the exchanges of this group for several months, this my first posting. I have (at 79) learned a lot from the pooled knowledge and experience of the group members. My inquiry ties in with posts regarding estradiol and the PATCH trial that have appeared the last couple
Although I have been following the exchanges of this group for several months, this my first posting. I have (at 79) learned a lot from the pooled knowledge and experience of the group members. My inquiry ties in with posts regarding estradiol and the PATCH trial that have appeared the last couple
Cliff-hanger
in
Advanced Prostate Cancer
6 months ago
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