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Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, only 65% of HR/VHR
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, only 65% of HR/VHR
janebob99
in
Prostate Cancer Network
6 months ago
Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
janebob99
in
Advanced Prostate Cancer
6 months ago
Transdermal estrogen/estradiol as monotherapy for Prostate Cancer
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Lost_Sheep
in
Prostate Cancer Network
6 months ago
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Dienogest and letrozole
Hi all, Could I get some advise please. I have been suffering from endometriosis. I had a recent MRI and ultrasound done few weeks back and they found deep infiltrating endometriosis in some areas, around perineum to be exact and a very tiny cyst on my left ovary. I had a 2nd laparoscopy a year ago and
Hi all, Could I get some advise please. I have been suffering from endometriosis. I had a recent MRI and ultrasound done few weeks back and they found deep infiltrating endometriosis in some areas, around perineum to be exact and a very tiny cyst on my left ovary. I had a 2nd laparoscopy a year ago and
ElsaKim
in
Endometriosis UK
10 months ago
Advice for estrogen vaginal cream
I've been using Estradiol (vaginal estrogen cream) for about a year or so. I've always used the applicator to apply the cream but I'm wondering if I can just smear the cream on with my finger. How many of you ladies apply the cream with your finger? I'm afraid if I don't use the applicator and don't
I've been using Estradiol (vaginal estrogen cream) for about a year or so. I've always used the applicator to apply the cream but I'm wondering if I can just smear the cream on with my finger. How many of you ladies apply the cream with your finger? I'm afraid if I don't use the applicator and don't
sungirl55
in
Menopause and Perimenopause Support
6 months ago
Estradiol E2 results 119pmol/L
I was scheduled to start my IVF circle this month but has been postponed ,the doctor is saying my estrogen level is high at 119pmol/L on day 2 ,Im confused tmsince if i convert this level in pg\nl is 32.4, please share your views on this.Thanks
I was scheduled to start my IVF circle this month but has been postponed ,the doctor is saying my estrogen level is high at 119pmol/L on day 2 ,Im confused tmsince if i convert this level in pg\nl is 32.4, please share your views on this.Thanks
KHMSJ
in
Fertility Network UK
6 months ago
Are my remaining symptoms perimenopause?
I've just done bloods after 13 weeks on a stable dose (150mcg T4 & 30mcg T3) which are as follows: TSH: 0.007 T4: 18.7 (12-22) 67% T3: 6 (3.1 - 6.8) 78% My vits are low but also stable since I quit gluten, I will work on them. Folate: 12.2 (>7) Vit D: 67 (50-250) Ferritin: 77 (30-150) Recent female
I've just done bloods after 13 weeks on a stable dose (150mcg T4 & 30mcg T3) which are as follows: TSH: 0.007 T4: 18.7 (12-22) 67% T3: 6 (3.1 - 6.8) 78% My vits are low but also stable since I quit gluten, I will work on them. Folate: 12.2 (>7) Vit D: 67 (50-250) Ferritin: 77 (30-150) Recent female
WitchingHour2point0
in
Thyroid UK
6 months ago
Vaginal Tablets Estradiol
Hi I've been on Tibolone since having full hysterectomy 3 years ago, following severe and rapid growing endometriosis. I went through such an ordeal with multiple surgeries in the end and whilst I'm ok and pain free now, it's always in the back of my mind that the endo could come back. I've been prescribed
Hi I've been on Tibolone since having full hysterectomy 3 years ago, following severe and rapid growing endometriosis. I went through such an ordeal with multiple surgeries in the end and whilst I'm ok and pain free now, it's always in the back of my mind that the endo could come back. I've been prescribed
catsrule40
in
Endometriosis UK
6 months ago
11dp5dt bfp but spotting
Hi looking for reassurance or anyone with a similar story. I’m currently 11dp5dt and have had positive tests since day 5 which I’m very happy about. However today I noticed a bit of light brown discharge and then half an hour later wiped away dark red blood. There was loads of it but enough to make me
Hi looking for reassurance or anyone with a similar story. I’m currently 11dp5dt and have had positive tests since day 5 which I’m very happy about. However today I noticed a bit of light brown discharge and then half an hour later wiped away dark red blood. There was loads of it but enough to make me
Victoria27
in
Fertility Network UK
7 months ago
Private Consultation Findings - thoughts on next steps
Hello everyone. I am looking for some advice and experiences on Dienogest / Zalkya. Diagnosed in 2022 via lap by general gynae and never prescribed anything. Own GP has tried me on contraceptives & meds for pain management, which nearly tipped me over the edge. After a scare with my mental health,
Hello everyone. I am looking for some advice and experiences on Dienogest / Zalkya. Diagnosed in 2022 via lap by general gynae and never prescribed anything. Own GP has tried me on contraceptives & meds for pain management, which nearly tipped me over the edge. After a scare with my mental health,
usernames123
in
Endometriosis UK
10 months ago
Estradiol pessaries
Hi,have been prescribed these pessaries doctor said it was fine to take,I've had a DVT 30 years ago a little worried about them!!any advice
Hi,have been prescribed these pessaries doctor said it was fine to take,I've had a DVT 30 years ago a little worried about them!!any advice
Sandlover
in
Cholesterol Support
7 months ago
please help us!
Hi everyone, Need some advice. This is our 7th ivf cycle. Last cycle we had: Day 9: 4 x 17, 21, 19, 16, 15, 15, 14, 14, 12 Oestradiol 9000 We collected 8 eggs, 5 mature, 1 transferred BFN and 1 mosaic embryo We are a bit concerned with our numbers for this cycle: Follicle count at baseline
Hi everyone, Need some advice. This is our 7th ivf cycle. Last cycle we had: Day 9: 4 x 17, 21, 19, 16, 15, 15, 14, 14, 12 Oestradiol 9000 We collected 8 eggs, 5 mature, 1 transferred BFN and 1 mosaic embryo We are a bit concerned with our numbers for this cycle: Follicle count at baseline
SD5117
in
Fertility Network UK
7 months ago
HRT Patches Concern
I recently switched to transdermal HRT tablets from oral HRT, I'm not convinced, firstly because of my very abrupt menopause,mine was like falling off a tall building 🗼rather than a gentle decline. So I was taking 1mg estradiol and I femoston conti 1/10 tablet a day for 7 years making 2mg oestrogen
I recently switched to transdermal HRT tablets from oral HRT, I'm not convinced, firstly because of my very abrupt menopause,mine was like falling off a tall building 🗼rather than a gentle decline. So I was taking 1mg estradiol and I femoston conti 1/10 tablet a day for 7 years making 2mg oestrogen
Sparklingsunshine
in
Thyroid UK
7 months ago
Endo results - meno or thyroid?
55 year old hypo diagnosed 20+ years ago, family history of hypo ( nan, mum and sister) . I also have vitiligo from my early 20s. I was tested for dry eyes when I was a teenager , so I think I've been hypo a long time.
Oct 23 GP bloods showed TSH 0.1, T4 18.9.
This was 12 hrs after my
55 year old hypo diagnosed 20+ years ago, family history of hypo ( nan, mum and sister) . I also have vitiligo from my early 20s. I was tested for dry eyes when I was a teenager , so I think I've been hypo a long time.
Oct 23 GP bloods showed TSH 0.1, T4 18.9.
This was 12 hrs after my
klfaz
in
Thyroid UK
7 months ago
weight changes on Estradiol and cyclogest for FET
I’m waiting for the go ahead to start estradiol and then cyclogest as part of the prep for a FET but really struggled with the weight I gained during the 3 cycles we had. We had 3 cycles in 3 months and I gained so much weight with the stress and drugs. I’ve had a little gap in-between the last retrieval
I’m waiting for the go ahead to start estradiol and then cyclogest as part of the prep for a FET but really struggled with the weight I gained during the 3 cycles we had. We had 3 cycles in 3 months and I gained so much weight with the stress and drugs. I’ve had a little gap in-between the last retrieval
Emjem84
in
Fertility Network UK
7 months ago
Latest Thyroid Results
My ‘thyroid journey’ has been an interesting one and now approaching its 4th year. I’m fairly convinced I don’t have autoimmune thyroid disease and relatively confident my adrenals play a big part in my symptoms, however it’s not just adrenals as I’ve tested myself on HC solo and it doesn’t work. Aaanyway
My ‘thyroid journey’ has been an interesting one and now approaching its 4th year. I’m fairly convinced I don’t have autoimmune thyroid disease and relatively confident my adrenals play a big part in my symptoms, however it’s not just adrenals as I’ve tested myself on HC solo and it doesn’t work. Aaanyway
Jamima
in
Thyroid UK
7 months ago
additional test results
Hi, After my initial blood tests (listed in my previous post) 2 weeks ago showed hypothyroidism and iron deficient anemia my gp ordered some additional tests to establish the cause. These were taken at 8:45am in the morning fasted. Please could you help me interpret what they mean? If they are ‘normal
Hi, After my initial blood tests (listed in my previous post) 2 weeks ago showed hypothyroidism and iron deficient anemia my gp ordered some additional tests to establish the cause. These were taken at 8:45am in the morning fasted. Please could you help me interpret what they mean? If they are ‘normal
Phoenix_24
in
Thyroid UK
7 months ago
Estrogen vs ADT?
I've read 5 recent papers that discuss the use of estrogen as an alternative treatment to ADT (Lupron, etc.). The new data looks very favorable. A bit of history. Huggins discovered this effect around 1941-44, and he found that high doses of estrogen (estradiol) efficiently castrated men, which
I've read 5 recent papers that discuss the use of estrogen as an alternative treatment to ADT (Lupron, etc.). The new data looks very favorable. A bit of history. Huggins discovered this effect around 1941-44, and he found that high doses of estrogen (estradiol) efficiently castrated men, which
janebob99
in
Prostate Cancer Network
7 months ago
Hashimotos - understanding latest blood test results - any advice for next steps?
Hi all, my partner (44F) has been struggling with hypothyroid / possible PCOS symptoms for ~18 months (thinning hair all over, some hirsutism and weight gain). She was diagnosed with Hashimotos in October 2022. We have been trying an approach to tackle both the thyroid issues and the hyperandrogenism
Hi all, my partner (44F) has been struggling with hypothyroid / possible PCOS symptoms for ~18 months (thinning hair all over, some hirsutism and weight gain). She was diagnosed with Hashimotos in October 2022. We have been trying an approach to tackle both the thyroid issues and the hyperandrogenism
Ehal89
in
Thyroid UK
7 months ago
PSA suppression
My PSA lows tend to be around 3.3, and it occurs to me that some might think it odd that I don't drive it lower. I think it is very common for men on ADT to draw too much comfort from a significant PSA reduction, if not a near-zero PSA. I have witnessed men misinterpret a dramatic drop in PSA as
My PSA lows tend to be around 3.3, and it occurs to me that some might think it odd that I don't drive it lower. I think it is very common for men on ADT to draw too much comfort from a significant PSA reduction, if not a near-zero PSA. I have witnessed men misinterpret a dramatic drop in PSA as
pca2004
in
Fight Prostate Cancer
8 months ago
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