Here's a plot of the Estradiol serum concentration (pg/mL) as a function of total dose (micrograms) of estrogen patches over 1 week. The plot tells the number of patches and how often to change them.
The three data points fall nicely on a straight line, which makes good sense.
The PATCH study used four, 100 microgram E2 patches, changed twice weekly.
Written by
janebob99
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