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Diamine oxidase
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Champix…The choice..!!
Seeing a lot of Champix quitters on the forum and being one myself I would like to explain what I have learned with the use of Champix: "Everything is a choice" (Anonymous). We can escape from the tyranny of our bad habits using any method that works. We have free will. The upside down mornings or
Seeing a lot of Champix quitters on the forum and being one myself I would like to explain what I have learned with the use of Champix: "Everything is a choice" (Anonymous). We can escape from the tyranny of our bad habits using any method that works. We have free will. The upside down mornings or
Hercu
Valued Contributor
in
No Smoking Day
7 years ago
Terminal density, terminal arbor size
Does anyone understand these terms and the likes of them and what their relevance to RLS might be? Here's three medical papers with such terms: "Effects of long-term treatment with dopamine receptor agonists and antagonists on terminal arbor size." https://www.ncbi.nlm.nih.gov/pubmed/12372014 "D2 Dopamine
Does anyone understand these terms and the likes of them and what their relevance to RLS might be? Here's three medical papers with such terms: "Effects of long-term treatment with dopamine receptor agonists and antagonists on terminal arbor size." https://www.ncbi.nlm.nih.gov/pubmed/12372014 "D2 Dopamine
ironbrain
in
Restless Legs Syndrome
7 years ago
Recently diagnosed with Parkinson's syndrome.
I had Dte In 2016 I fell backwards and hit my head on my street pretty hard. It was hard enough to cause u huge lump on the ack of my head. I also had passed out. I went to the ER, where they did an MRI and a CAT scan they found nothing. But now a little over a year I have had my left arm jerking
I had Dte In 2016 I fell backwards and hit my head on my street pretty hard. It was hard enough to cause u huge lump on the ack of my head. I also had passed out. I went to the ER, where they did an MRI and a CAT scan they found nothing. But now a little over a year I have had my left arm jerking
Hidden
in
Cure Parkinson's
7 years ago
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A second medication
Hi everyone. I'm after a bit of advice. I'm looking for something I can take for RLS a couple of times a week that it not an opiate. I already take codeine but can't take it every day due to tolerance build up-it just doesn't work when I do that.I don't want to take a dopamine agonist for fear of augmentation
Hi everyone. I'm after a bit of advice. I'm looking for something I can take for RLS a couple of times a week that it not an opiate. I already take codeine but can't take it every day due to tolerance build up-it just doesn't work when I do that.I don't want to take a dopamine agonist for fear of augmentation
Jumpey
in
Restless Legs Syndrome
7 years ago
Augmentation, opiates, benzodiazepines
I read a lot on here about the danger of augmentation with dopamine agonists and of switching to opiates. But from what I read, opiates are also dopamine agonists. My doc is probably about as keen to let me have opiates or even benzodiazepines as offer an alcohol a drink. I, myself, have thought occasionally
I read a lot on here about the danger of augmentation with dopamine agonists and of switching to opiates. But from what I read, opiates are also dopamine agonists. My doc is probably about as keen to let me have opiates or even benzodiazepines as offer an alcohol a drink. I, myself, have thought occasionally
ironbrain
in
Restless Legs Syndrome
7 years ago
Tremor when excited/involved/emotional
Can someone please help me understand the science behind why I get all shaky when I'm in the spotlight? I'm not nervous or afraid, and it's one of the latest symptoms, in the past 8 to 10 weeks. I'm more gait dominant and don't have a tremor otherwise, but the more involved I am in a good conversation
Can someone please help me understand the science behind why I get all shaky when I'm in the spotlight? I'm not nervous or afraid, and it's one of the latest symptoms, in the past 8 to 10 weeks. I'm more gait dominant and don't have a tremor otherwise, but the more involved I am in a good conversation
Stebenjoe
in
Cure Parkinson's
7 years ago
Disco legs
Hi i am new to the forum but alas not to RLS or disco legs as my partner affectionately refers to it 😊. I have tried all the usual remedies with no joy. I did manage to get hold of some diazepam from a friend only 2mg dose which was amazing in aiding a good nights sleep. I asked the doctor for a prescription
Hi i am new to the forum but alas not to RLS or disco legs as my partner affectionately refers to it 😊. I have tried all the usual remedies with no joy. I did manage to get hold of some diazepam from a friend only 2mg dose which was amazing in aiding a good nights sleep. I asked the doctor for a prescription
Sarahlouw
in
Restless Legs Syndrome
7 years ago
ScienceofParkinsons, locus coeruleus, and norepinephrine
Although essays in ScienceOfParkinsons.com are informative, they merit scrutiny. Yes, atypicalities of alpha-synuclein and pathologies in dopaminergic processes are important, as are dopamine-related treatments. However, focusing entirely upon dopamine seems to be an error of omission
Although essays in ScienceOfParkinsons.com are informative, they merit scrutiny. Yes, atypicalities of alpha-synuclein and pathologies in dopaminergic processes are important, as are dopamine-related treatments. However, focusing entirely upon dopamine seems to be an error of omission
aspergerian
in
Cure Parkinson's
7 years ago
Dangers of neupro patch
Dx'd at 27 Started 4 mg nuepro patch 3 years ago when I was 36 Side effects were extreme Impulse control disorder issues big time Major behavioral changes Experienced extreme hypomania (bipolar disorder)symptoms Quit using nuepro patch year and half after starting it Went through over a
Dx'd at 27 Started 4 mg nuepro patch 3 years ago when I was 36 Side effects were extreme Impulse control disorder issues big time Major behavioral changes Experienced extreme hypomania (bipolar disorder)symptoms Quit using nuepro patch year and half after starting it Went through over a
k100
in
Cure Parkinson's
7 years ago
Stimulating dopamine production
I used to naively think one 'used up' dopamine when one moved. After all you need dopamine to move, but apparently the opposite is true. Any movement, even passive movement (when someone moves your limbs for example), stimulates dopamine production. And it's like a dynamo, the brain needs less stimulation
I used to naively think one 'used up' dopamine when one moved. After all you need dopamine to move, but apparently the opposite is true. Any movement, even passive movement (when someone moves your limbs for example), stimulates dopamine production. And it's like a dynamo, the brain needs less stimulation
Dap1948
in
Cure Parkinson's
7 years ago
Neurotransmitter-nutrient relationship (from Dr. Walsh's book "Nutrient Power: heal you biochemistry, heal your brain")
On p.151 there is a table which lists 5 neurotransmitters (serotonin, dopamine, norepinephrine, NMDA, GABA) and nutrients affecting them - in case some of you might be interested in looking at them, here are the ones affecting dopamine: Increased activity : tyrosine, phenylalanine, vitamins B1, B6,
On p.151 there is a table which lists 5 neurotransmitters (serotonin, dopamine, norepinephrine, NMDA, GABA) and nutrients affecting them - in case some of you might be interested in looking at them, here are the ones affecting dopamine: Increased activity : tyrosine, phenylalanine, vitamins B1, B6,
faridaro
in
Cure Parkinson's
7 years ago
Sex and dopamine
Research has found that 'mating' stimulates dopamine production IN MEN! Apparently women need to engage in 'nesting' to achieve the same effect! Yes nesting is housework and tidying but it is also shopping! Another tip from my sessions with Dr Farias fariastechnique.com
Research has found that 'mating' stimulates dopamine production IN MEN! Apparently women need to engage in 'nesting' to achieve the same effect! Yes nesting is housework and tidying but it is also shopping! Another tip from my sessions with Dr Farias fariastechnique.com
Dap1948
in
Cure Parkinson's
7 years ago
Exercise to Fight Anxiety/Depression
Exercise increases the happy feel good chemicals such as serotonin, norepinephrine, and dopamine - important neurotransmitters that traffic in thoughts and emotions, it also lowers the bad chemicals that lead to anxiety and depression such as Cortisol and too much Adrenaline (Fight or Flight) (Serotonin
Exercise increases the happy feel good chemicals such as serotonin, norepinephrine, and dopamine - important neurotransmitters that traffic in thoughts and emotions, it also lowers the bad chemicals that lead to anxiety and depression such as Cortisol and too much Adrenaline (Fight or Flight) (Serotonin
Hidden
in
Anxiety Support
7 years ago
Methylation and PD
From Dr. Ben Lynch's article: http://mthfr.net/taking-folate-and-feeling-badly-methylation-requires-balance/2011/11/15/ "IMPORTANT!! Increased methylation may cause – and does cause – neurological symptoms. Methylation reactions increase in aging, the symptoms of Parkinson’s Disease (PD) are strikingly
From Dr. Ben Lynch's article: http://mthfr.net/taking-folate-and-feeling-badly-methylation-requires-balance/2011/11/15/ "IMPORTANT!! Increased methylation may cause – and does cause – neurological symptoms. Methylation reactions increase in aging, the symptoms of Parkinson’s Disease (PD) are strikingly
faridaro
in
Cure Parkinson's
7 years ago
The benefits of exercising to music
One aspect of Parkinson's is the body's desire not to move, which it achieves by reducing dopamine production and freezing, rigidity and bradykinesia. Playing loud, low, beat-y music at between 100-120 beats per minute while you exercise eliminates the freezing response and allows you to move much more
One aspect of Parkinson's is the body's desire not to move, which it achieves by reducing dopamine production and freezing, rigidity and bradykinesia. Playing loud, low, beat-y music at between 100-120 beats per minute while you exercise eliminates the freezing response and allows you to move much more
Dap1948
in
Cure Parkinson's
7 years ago
Cannot sleep 😴
This sucks! I have always had issues with insomnia but now it seems a cruel twist of fate. I get to enjoy every possible moment . It may seem silly but I find the best way to cope with pain is to keep your mind off of it. Distract yourself, dress up. If you look good , you will feel better. Children
This sucks! I have always had issues with insomnia but now it seems a cruel twist of fate. I get to enjoy every possible moment . It may seem silly but I find the best way to cope with pain is to keep your mind off of it. Distract yourself, dress up. If you look good , you will feel better. Children
Damaged
in
NRAS
7 years ago
L Tyrosine may be helpful
My next attempt at relief is to try L Tyrosine is a non essential amino acid that is the precursor of the neurotransmitter, dopamine. Tyrosine is converted into Levodihydrophenylalanine (L-Dopa) and L-Dopa is subsequently and avidly converted into dopamine. More on the subject here:https://clinicaltrials.gov
My next attempt at relief is to try L Tyrosine is a non essential amino acid that is the precursor of the neurotransmitter, dopamine. Tyrosine is converted into Levodihydrophenylalanine (L-Dopa) and L-Dopa is subsequently and avidly converted into dopamine. More on the subject here:https://clinicaltrials.gov
BoldMove
in
Restless Legs Syndrome
7 years ago
4 DAYS INTO COLD TURKEY ON CLONIDINE ALL IS GOING PRETTY WELL EXCEPT. . .need more advice at this point.
HI ALL—AN UP DATE and advice still needed: I am 4 days into cold turkey, stopped 2 mg. regular Ropinerole Friday. No augmentation or anything, not a twinge the first 24 hours. The second day, I had an augmentation response half way through the day, after taking my a Clonidine 0.01mg. Took some Iron
HI ALL—AN UP DATE and advice still needed: I am 4 days into cold turkey, stopped 2 mg. regular Ropinerole Friday. No augmentation or anything, not a twinge the first 24 hours. The second day, I had an augmentation response half way through the day, after taking my a Clonidine 0.01mg. Took some Iron
Bganim1947
in
Restless Legs Syndrome
7 years ago
Just shut up and take your meds!
Hi all My vlog about levodopa and dopamine agonists used in the treatment of Parkinson's Disease, their effects and side effects. https://youtu.be/xVKXx5a-qbs Cheers, Ian
Hi all My vlog about levodopa and dopamine agonists used in the treatment of Parkinson's Disease, their effects and side effects. https://youtu.be/xVKXx5a-qbs Cheers, Ian
Ianfrizell
in
Cure Parkinson's
7 years ago
dopamine???
hi, my name is greg, I've been suffering with rls for 10yrs now I'm currently taking 4mg a day of mirapex and it's getting worse, my neurologist wants to put me on dopamine, to see if that helps, but I'm concerned about the withdrawal from mirapex???
hi, my name is greg, I've been suffering with rls for 10yrs now I'm currently taking 4mg a day of mirapex and it's getting worse, my neurologist wants to put me on dopamine, to see if that helps, but I'm concerned about the withdrawal from mirapex???
gvine59
in
Restless Legs Syndrome
7 years ago
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