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Diamine oxidase
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Why I want to research active microbiome therapies for Parkinsons
Why I think the microbiome is key (Stick with it – links to poo coming up…) Having been diagnosed with PD, and offered regular Sinemet therapy, I resolved to look for alternatives and hope for a cure. Dopamine – whilst central to PD and effectively the definition of the disease, appears to be only part
Why I think the microbiome is key (Stick with it – links to poo coming up…) Having been diagnosed with PD, and offered regular Sinemet therapy, I resolved to look for alternatives and hope for a cure. Dopamine – whilst central to PD and effectively the definition of the disease, appears to be only part
WinnieThePoo
in
Cure Parkinson's
5 years ago
Help! How do you time your eating with taking Sinemet?
Hi folks, this is willason, this is my second post. Thanks to everyone who communicated with me on my first post. I've been having so many problems the past few weeks managing my PD. I'm sure many of you can relate. One of my problems is managing when I eat in relation to when I take my Sinemet.
Hi folks, this is willason, this is my second post. Thanks to everyone who communicated with me on my first post. I've been having so many problems the past few weeks managing my PD. I'm sure many of you can relate. One of my problems is managing when I eat in relation to when I take my Sinemet.
willason
in
Cure Parkinson's
5 years ago
Ongoing stem cell clinical trials for PD
According to clinicaltrials.gov, there are 26 trials in progress which are stem cell based. The link to the list is as follows https://clinicaltrials.gov/ct2/results?term=stem+cells+AND+parkinson%27s Four groups dedicated to using stem cell therapies to treat Parkinson’s disease have formed an international
According to clinicaltrials.gov, there are 26 trials in progress which are stem cell based. The link to the list is as follows https://clinicaltrials.gov/ct2/results?term=stem+cells+AND+parkinson%27s Four groups dedicated to using stem cell therapies to treat Parkinson’s disease have formed an international
Farooqji
in
Cure Parkinson's
5 years ago
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Review of Dr Marty Hinz amino acid protocol for the treatment of Parkinson’s Disease
Dr Marty Hinz amino acid protocol for the treatment of Parkinson’s Disease This summary is the result of a detailed study I have made based on reading a whole range of papers published by Dr Marty Hinz and his colleagues as well as papers he refers to published by other researchers. It is certainly
Dr Marty Hinz amino acid protocol for the treatment of Parkinson’s Disease This summary is the result of a detailed study I have made based on reading a whole range of papers published by Dr Marty Hinz and his colleagues as well as papers he refers to published by other researchers. It is certainly
wriga
in
Cure Parkinson's
5 years ago
Is it possible to upload a file to this site?
Does anyone know if you can upload a file to this site? I thought I would upload the DNA analysis , urine analysis and SIBO files that we have had done on my husband for anyone interested in seeing the kinds of information you get from these tests but I am not sure if it is possible. It would be quite
Does anyone know if you can upload a file to this site? I thought I would upload the DNA analysis , urine analysis and SIBO files that we have had done on my husband for anyone interested in seeing the kinds of information you get from these tests but I am not sure if it is possible. It would be quite
LAJ12345
in
Cure Parkinson's
6 years ago
Informative article with links re PD and Gut microbiome
Gut-Brain Gateways to Parkinson's Once it was thought that Parkinson’s disease (PD) was primarily a central nervous system condition that impinges upon motor function, but now we know that it entails critical inputs from the enteric nervous system (ENS), intestinal and brain barriers, exposome,
Gut-Brain Gateways to Parkinson's Once it was thought that Parkinson’s disease (PD) was primarily a central nervous system condition that impinges upon motor function, but now we know that it entails critical inputs from the enteric nervous system (ENS), intestinal and brain barriers, exposome,
Jandeb
in
Cure Parkinson's
6 years ago
Triple herbal extract DA-9805 exerts a neuroprotective effect
Moutan cortex, Angelica Dahurica root, and Bupleurum root are traditional herbal medicines used in Asian countries to treat various diseases caused by oxidative stress or inflammation. In the MPTP-induced subacute PD model mice, oral administration of DA-9805 (Moutan cortex, Angelica Dahurica root, and
Moutan cortex, Angelica Dahurica root, and Bupleurum root are traditional herbal medicines used in Asian countries to treat various diseases caused by oxidative stress or inflammation. In the MPTP-induced subacute PD model mice, oral administration of DA-9805 (Moutan cortex, Angelica Dahurica root, and
Farooqji
in
Cure Parkinson's
6 years ago
Ropinirole for long airplane flights?
My daughter, aged 44, also suffers from restless leg syndrome. She manages her condition without medication. However, she finds long flights miserable and her primary care physician has scripted her ropinirole and suggests starting a couple of weeks before the next long flight. I am questioning staying
My daughter, aged 44, also suffers from restless leg syndrome. She manages her condition without medication. However, she finds long flights miserable and her primary care physician has scripted her ropinirole and suggests starting a couple of weeks before the next long flight. I am questioning staying
whiteleye
in
Restless Legs Syndrome
6 years ago
Levetiracetam (Keppra) to help in some cases of RLS.
Tim61, I posted recently about withdrawing from Pramipexole, which I’m doing at the moment, not very nice. My GP eventually discovered I was suffering with myoclonic jerks, not restless leg syndrome. I saw him yesterday’ & he has agreed to try keppra ( levetiracetam) 250mg at night. I took the first
Tim61, I posted recently about withdrawing from Pramipexole, which I’m doing at the moment, not very nice. My GP eventually discovered I was suffering with myoclonic jerks, not restless leg syndrome. I saw him yesterday’ & he has agreed to try keppra ( levetiracetam) 250mg at night. I took the first
Tim61
in
Restless Legs Syndrome
6 years ago
Anyone else had insomnia on Ropinirole? What do I try next?!
Hello all I have severe PLMS and have had an iron infusion (ferritin level remains good five months later), pregabalin 100mg (couldn't cope with the side effects) and ropinirole 1mg. I barely slept for the month I was on ropinirole and, from what I can find here and on the net generally, this isn't
Hello all I have severe PLMS and have had an iron infusion (ferritin level remains good five months later), pregabalin 100mg (couldn't cope with the side effects) and ropinirole 1mg. I barely slept for the month I was on ropinirole and, from what I can find here and on the net generally, this isn't
Hidden
in
Restless Legs Syndrome
6 years ago
Research Transforming Mature Neurons into Dopamine Factories could Help Fight Brain Diseases
Researchers accidentally converted mature neurons into dopaminergic cells (in green) without first reverting them to a stem-cell state. https://blog.cirm.ca.gov/2018/10/22/research-transforming-mature-neurons-into-dopamine-factories-could-help-fight-brain-diseases/amp/?__twitter_impression=true
Researchers accidentally converted mature neurons into dopaminergic cells (in green) without first reverting them to a stem-cell state. https://blog.cirm.ca.gov/2018/10/22/research-transforming-mature-neurons-into-dopamine-factories-could-help-fight-brain-diseases/amp/?__twitter_impression=true
Farooqji
in
Cure Parkinson's
6 years ago
Beyond Dopamine: GABA, Glutamate, and the Axial Symptoms of PD
Beyond Dopamine: GABA, Glutamate, and the Axial Symptoms of Parkinson Disease. Ruth L. O'Gorman Tuura, Christian R. Baumann, and Heide Baumann-Vogel. 2018. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168661/
Beyond Dopamine: GABA, Glutamate, and the Axial Symptoms of Parkinson Disease. Ruth L. O'Gorman Tuura, Christian R. Baumann, and Heide Baumann-Vogel. 2018. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168661/
aspergerian13
in
Cure Parkinson's
6 years ago
Is RLS / PLMS really the cause of all my problems ?
I hope everyone is well and that the responses to my post are helpful to others as well as for myself. Apologies for the long post and the long list of questions Before having ever taken any medication my symptoms are constant significant fatigue, memory loss, cognitive decline. My vision is significantly
I hope everyone is well and that the responses to my post are helpful to others as well as for myself. Apologies for the long post and the long list of questions Before having ever taken any medication my symptoms are constant significant fatigue, memory loss, cognitive decline. My vision is significantly
DesperateDann
in
Restless Legs Syndrome
6 years ago
Looking for various so called causes of RLS
Can anyone give me a list of ALL the 'causes' of RLS. There have been so many starting with lack of magnesium. I am not interested in the 'band aid' drugs we are all given but rather the suspected etiology (the cause) of RLS. Recently Johns Hopkins Hospital said it was too much glutamine in the brain
Can anyone give me a list of ALL the 'causes' of RLS. There have been so many starting with lack of magnesium. I am not interested in the 'band aid' drugs we are all given but rather the suspected etiology (the cause) of RLS. Recently Johns Hopkins Hospital said it was too much glutamine in the brain
auntiesioux
in
Restless Legs Syndrome
6 years ago
Mucuna Pruriens as a dopamine agonist and Aspartame
A few things I have read - I wonder if people have noticed a difference taking aspartame out of their diet and adding Mucuna Prurients. I personally avoid artificial sweeteners but have not tried Mucuna. "Aspartame is a synthetic, laboratory concocted, genetically modified, sugar-replacement nightmare
A few things I have read - I wonder if people have noticed a difference taking aspartame out of their diet and adding Mucuna Prurients. I personally avoid artificial sweeteners but have not tried Mucuna. "Aspartame is a synthetic, laboratory concocted, genetically modified, sugar-replacement nightmare
Goldy700
in
Restless Legs Syndrome
6 years ago
My subtype : Postprandial and orthostatic hypotension in Parkinson's disease. 1987
An early study. Postprandial and orthostatic hypotension in Parkinson's disease. Micieli G, et al. Neurology. 1987. https://www.ncbi.nlm.nih.gov/m/pubmed/3822130/ In this study, the 24-hour pattern of blood pressure (BP), heart rate, and urinary catecholamine (CA) excretion and the response of BP
An early study. Postprandial and orthostatic hypotension in Parkinson's disease. Micieli G, et al. Neurology. 1987. https://www.ncbi.nlm.nih.gov/m/pubmed/3822130/ In this study, the 24-hour pattern of blood pressure (BP), heart rate, and urinary catecholamine (CA) excretion and the response of BP
aspergerian13
in
Cure Parkinson's
6 years ago
Have someone had an experience with a supplement that works as a MAO inhibitor in PD?
After 12 years in PD I am struggling with shuffling and freezing during the last two years. To me they are the most disgusting symptoms of Parkinson's. At beginning of my illness I used to manage it with Wellbutrin Xl (bupropion) and it was great to the extent that I felt like Parkinson did not affected
After 12 years in PD I am struggling with shuffling and freezing during the last two years. To me they are the most disgusting symptoms of Parkinson's. At beginning of my illness I used to manage it with Wellbutrin Xl (bupropion) and it was great to the extent that I felt like Parkinson did not affected
marnegro
in
Cure Parkinson's
6 years ago
Apomorphine Benefits Finally Confirmed in Parkinson's
The benefits of the dopamine agonist apomorphine in Parkinson's disease have finally been confirmed in a randomized controlled trial, although the drug has been used in the condition for many years https://www.medscape.com/viewarticle/901709
The benefits of the dopamine agonist apomorphine in Parkinson's disease have finally been confirmed in a randomized controlled trial, although the drug has been used in the condition for many years https://www.medscape.com/viewarticle/901709
Farooqji
in
Cure Parkinson's
6 years ago
How I tried to keep my Dopamine agonist dose under control for >10 years
I just now read a comment by involuntary dancer who wondered if reducing dose when effectiveness goes down might help to get a longer effective period out of dopamine agonist treatments. Since this community had provided me with so many invaluable knowledge and thoughts about how to live with this condition
I just now read a comment by involuntary dancer who wondered if reducing dose when effectiveness goes down might help to get a longer effective period out of dopamine agonist treatments. Since this community had provided me with so many invaluable knowledge and thoughts about how to live with this condition
Wonko_TheSane
in
Restless Legs Syndrome
6 years ago
Therapeutic strategies for Parkinson disease: beyond dopaminergic drugs
Existing therapeutic strategies for managing Parkinson disease (PD), which focus on addressing the loss of dopamine and dopaminergic function linked with degeneration of dopaminergic neurons, are limited by side effects and lack of long-term efficacy. In recent decades, research into PD pathophysiology
Existing therapeutic strategies for managing Parkinson disease (PD), which focus on addressing the loss of dopamine and dopaminergic function linked with degeneration of dopaminergic neurons, are limited by side effects and lack of long-term efficacy. In recent decades, research into PD pathophysiology
Farooqji
in
Cure Parkinson's
6 years ago
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