Levodopa: Has anybody had any... - Restless Legs Syn...

Restless Legs Syndrome

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Levodopa

Barnaby97 profile image
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Has anybody had any experience of taking the drug Levodopa, which is a Dopamine supplement / replacement?

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Barnaby97 profile image
Barnaby97
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9 Replies

The med Levodopa isnt used much these days for RLS. You can augment on it quite quickly. I will try to find some info for you.

Legsandmore profile image
Legsandmore

Yes l took it for my RLS, it was the very first prescription med my GP tried me on when the symptoms became unbearable.

I have to be honest and say it worked a treat for me at first but then augmented very quickly even on a low dose.

I subsequently learnt that it is not seen as a good choice for that reason and is viewed as a poor option for treating RLS as opposed to other drugs.

Hope that helps.

Birdman70 profile image
Birdman70

My first drug I tried for RLS was Sinimet. Its levadopa and carbidopa.....did nothing for me. Plus I found out from others that it is a bad augmentation drug

bvlgari profile image
bvlgari

I take ropinerole which is a dopamine drug. Couldn't be without it as I suffer 24/7.x

I've been on carbidopa/levodopa (sinemet) 50-200mg (CR) since mid-October breaking away from an 8 year run on pramipexole which ended in severe augmentation. 1 tablet at bedtime gets me about 4 hours sleep. Another 1/2 tablet then gets me another 3-4 hours. I didn't realize the augmentation potential with carb/levo. Anyone know how long it takes for augmentation to occur with carb/levo (sinimet)? And what has worked as a substitute for carb/levo?

mckerr profile image
mckerr

Been on it for 4 yrs. Now take 4-500mg every night. Only good thing is no side effects and acts quickly

Retren profile image
Retren

used for Parkinson's disease they also get RLS but it treats the disease never used it my-self ,also the side effects can be nasty.

Ikeeptrying profile image
Ikeeptrying

I've been on Sinemet, 200 Mg, plus 600 Mg of gabapentin minutes before bedtime . No rls at all. If there are side effects I don't know what they are. I get rummy in the morning but I think that's from the Trazadol I take right at bedtime. The Sinemet's really been good for me but I wouldn't be surprised if it stops working at any time. So I'm always looking for a Plan B.

LotteM profile image
LotteM

@Ikeeptrying, is this the combi of meds you still take every evening? And did you mean tramadol instead of trazodol? If yes to both questions, I wonder which med is doing what. I also wonder what made you take those three different types of meds.

Anyway, If your rls plays up again, focus on sinemet as the most likely culprit. But I hope dor you that will only be in the distant future.

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