Experiences with

Diamine oxidase

I also did a test which showed I have very low diamine oxidase in my gut so have histamine intolerance. My question is regarding my medication. I currently take 100mg sertraline, two blood pressure pills and a statin. Are these not getting into my system either?

And I also have low diamine oxidase which is used to control histamine. I would say my main issue at the movement is extreme fatigue which I am hoping to get to the bottom of soon!

Oxidase 3 times a day Vitamin D 3,000 to 4,000 IU daily This detox (NAC) will get rid of the spike protein to 98% and bring down the inflammation at cell level.

I'm low on ferritin (20) I was told I can't inject because it's low? My b12 was low 232 in 2021 with high mma. Last year when all my neuro symptoms started it was around 390 for b12. I took supplements a few times, it raised to 630 and then got one injection on 6/2024. One month later my b12 was 298

I've been taking a magnesium supplement for years, actually either magnesium glycinate or magnesium L threonate, magnesium oxide is a big no-no, it gives me weird stomach palpatations. But recently I've noticed that my preferred magnesium has been having the same effect, I didn't realise at first that

"L-theanine may help with restless legs syndrome (RLS) because it can increase GABA levels in the brain. GABA is a chemical that can help calm the brain. How it works L-theanine can be taken as a supplement or in tea. It's recommended to take it in the evening before bed. L-theanine can be taken

I stumbled upon a study I thought was interesting, in light of recent reports that PwPD harbor elevated levels of desulfovibrio in their microbiome. Desulfovibrio is a sulfur reducing bacteria (SRB). Sulfur reducing bacteria produce hydrogen sulfide, which in small amounts can be beneficial, but in larger

For anyone who has missed this, there is a new Clinical Practice Guideline from the AASM advising against the use of dopamine agonists for RLS except in some exceptional circumstances, strongly recommending iron therapy, and advising for gabapentinoids and low dose opioids. Here is a summary by Drs Berkowski

After 14 years on dopamine agonists (first ropinerole and now pramipexole) and the inevitable augmentation, I have been tapering off of pramipexole since last April. I am under the care of a neurologist who is educated about DAs and augmentation. I was taking 1 mg of pramipexole last April and am currently

Hi do you remember recently about Emmerdale bringing up the subject of gambling and sexulised behaviour as side effects ? I did a survey can't remember where it was from but I've had a BBC reporter wanting to talk to me about the side effects I had . Their doing a piece on it but your picture has to

I hear a lot of discussion about Dr. Laurie Mischley in this forum. She has been very helpful to me so I want to share my experience under her treatment. I am paraphrasing a letter of thanks I sent Dr Mischley recently. I have communicated with her via zoom for the last 4 years. I follow her dietary

I hear a lot of discussion about Dr. Laurie Mischley in this forum. She has been very helpful to me so I want to share my experience under her treatment. I am paraphrasing a letter of thanks I sent Dr Mischley recently. I have communicated with her via zoom for the last 4 years. I follow her

so a year after all my problems started I finally got my NHS appt with Dr Nijam Lovely bloke set my mind at rest regarding the twitching stiffness cramps etc that I wasn’t in early stages MND or Parkinson’s he was concerned my GP had put me on buprenorphine but I explained the painful damaged hip and

I'm seeing a neurologist this month after waiting for 6 years! In his letter to my Gp in response to the referral, he was suggesting l dopa. I'm guessing this is yet another dopamine agonist and wonder if anyone has experience of it?

This research is being done in Australia "Direct nose-to-brain delivery of dopamine is company’s goal Gel given directly to nasal passages might be more effective, longer lasting" By Andrea Lobo https://parkinsonsnewstoday.com/news/nose-brain-delivery-dopamine-parkinsons-company-goal/?utm_source=

This website is totally brilliant! I have learnt so much. Many thanks to all who give their time and energy to help others. Have had RLS since 2000, been on ropinerole since 2008 and, due to augmentation, am now on 7mg at night. Coping but only just. Live in UK, am in my 70s and female. Have an

I'm in the UK and recently there have been several articles in the press about the side effects of dopamine agonist, particularly compulsive behaviour. The BBC are planning to highlight people's experiences in a programme. I have been approached and I am under discussion with a journalist. I have to

Hi all, I've been very slowly tapering off Neupro for aroud 10 months and just a week ago I took my final dose which was a sixth of one miligram , down from 2 mg. I had been on the patch for around 5 years and augmented for many of those. With each reduction I have felt increased anxiety but I'm surprised

https://acrobat.adobe.com/id/urn:aaid:sc:EU:7137a930-39d8-40fe-85ed-e5d0887bcabc An interesting article in Podiatry Management. It appears that podiatrists know more about RLS than most UK medics. Maybe we should all be seeing podiatrists instead of GPs. They refer to the Mayo Clinic Algorithm , and

I listened to the Steven Bartlett podcast with Dr Lembke on dopamine and at the very beginning I felt thrilled about the test on rats and the effect of no dopamine because it confirmed how disabling a lack of dopamine is …. Yippee…I can stop doubting my adhd diagnosis! however….as the podcast progresses