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What Next After Xtandi Fail?
Morning all. Don't post much but now is the time. Been fighting the Beast since Nov 2016. On Lupron from the beginning and Xtandi since Nov 2019. Hit Nadir of .21 in Dec 2022. Since then, PSA has been jumping around, but trending upward. End of 2023, it was at .67. Feb 2024, PSA up to .87. Yesterday
Morning all. Don't post much but now is the time. Been fighting the Beast since Nov 2016. On Lupron from the beginning and Xtandi since Nov 2019. Hit Nadir of .21 in Dec 2022. Since then, PSA has been jumping around, but trending upward. End of 2023, it was at .67. Feb 2024, PSA up to .87. Yesterday
ppulatie
in
Advanced Prostate Cancer
4 months ago
Assessing the Benefit of CAR T-cell Therapies for mCRPC
A first-in-human phase 1 trial (NCT03873805) investigated the safety and bioactivity of prostate stem cell antigen-directed CAR T cells for patients with metastatic castration-resistant prostate cancer. CancerNetwork® spoke with Saul Priceman, PhD, associate professor and associate director of the
A first-in-human phase 1 trial (NCT03873805) investigated the safety and bioactivity of prostate stem cell antigen-directed CAR T cells for patients with metastatic castration-resistant prostate cancer. CancerNetwork® spoke with Saul Priceman, PhD, associate professor and associate director of the
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
Non invasive detection of neuroendocrine PCa
An innovation to detect neuroendocrine PCa...and one of the researchers is a friend so I wanted to promote this paper :-P https://www.urotoday.com/video-lectures/prostate-cancer/video/mediaitem/3995-non-invasive-detection-of-neuroendocrine-prostate-cancer-through-targeted-cell-free-dna-methylation-himisha-beltran-francesca-demichelis.html
An innovation to detect neuroendocrine PCa...and one of the researchers is a friend so I wanted to promote this paper :-P https://www.urotoday.com/video-lectures/prostate-cancer/video/mediaitem/3995-non-invasive-detection-of-neuroendocrine-prostate-cancer-through-targeted-cell-free-dna-methylation-himisha-beltran-francesca-demichelis.html
Maxone73
in
Advanced Prostate Cancer
5 months ago
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Pelvic Lymph Node Study
"Review suggests many men with early prostate cancer may not need lymph node removal." "Doing so may help them avoid harmful side effects, such as disabling lymphedema. But even more importantly, leaving the pelvic nodes intact might also boost the success of newer immune-based cancer drugs, the experts
"Review suggests many men with early prostate cancer may not need lymph node removal." "Doing so may help them avoid harmful side effects, such as disabling lymphedema. But even more importantly, leaving the pelvic nodes intact might also boost the success of newer immune-based cancer drugs, the experts
Nwdx
in
Fight Prostate Cancer
1 month ago
Very happy !!
Am pleased to say that the cystoscopy showed no irregularities, all clear and report now being forwarded to urologist . It's a tremendous relief for me and to be able to tell my husband and son they can now stop worrying. thanks to everyone who has listened to me and responded kindly to my messages
Am pleased to say that the cystoscopy showed no irregularities, all clear and report now being forwarded to urologist . It's a tremendous relief for me and to be able to tell my husband and son they can now stop worrying. thanks to everyone who has listened to me and responded kindly to my messages
gillsky8
in
PMRGCAuk
1 month ago
Toronto Prostate Cancer Specialist for Dad
My dad (68 years old) is visiting me (For my delivery in the first week of June) from India and he is going to be in Ontario, Canada for the next 3 months. He was diagnosed in Feb 2024 with a PSA of 24 and is completely asymptomatic. He is on hormone therapy with Gleason 8 and distant mets in his bones
My dad (68 years old) is visiting me (For my delivery in the first week of June) from India and he is going to be in Ontario, Canada for the next 3 months. He was diagnosed in Feb 2024 with a PSA of 24 and is completely asymptomatic. He is on hormone therapy with Gleason 8 and distant mets in his bones
Justgettingitright
in
Advanced Prostate Cancer
5 months ago
Six ways to reduce the risk of colorectal cancer
Exercise The US National Cancer Institute says that physically active adults can reduce their risk of developing
colon
cancer
by as much as 24%.
Exercise The US National Cancer Institute says that physically active adults can reduce their risk of developing
colon
cancer
by as much as 24%.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
5 months ago
whenever i raise euthyrox100mg i get hbp headache nausea
is two weeks now i raised euthyrox from 75 yo 100mg and i dont think i can tolerate twice i tried and got hbp that even pills dont take it down
is two weeks now i raised euthyrox from 75 yo 100mg and i dont think i can tolerate twice i tried and got hbp that even pills dont take it down
morcan54
in
Thyroid UK
5 months ago
Update, small cell
Hi everyone, It's been a while since I posted but check in time to time. I'm not really sure of the purpose of this update is except we don't have a lot of family so I'm hoping writing it down will help. Please be sensitive as I'm struggling. I really can't hear about should of dones. My husband was
Hi everyone, It's been a while since I posted but check in time to time. I'm not really sure of the purpose of this update is except we don't have a lot of family so I'm hoping writing it down will help. Please be sensitive as I'm struggling. I really can't hear about should of dones. My husband was
Fdccs
in
Advanced Prostate Cancer
5 months ago
New DX
I am a 76 yo woman. I was DX in 2016 and was in a trial at MD Anderson from 2017-2019. I achieved UMRD at the end of the trial of Ibrutinib and Venetoclax. I remained in total remission until my first visit after my husband died from Alzheimer’s in Oct 2021. Since then it’s been downhill. Dr Wierda
I am a 76 yo woman. I was DX in 2016 and was in a trial at MD Anderson from 2017-2019. I achieved UMRD at the end of the trial of Ibrutinib and Venetoclax. I remained in total remission until my first visit after my husband died from Alzheimer’s in Oct 2021. Since then it’s been downhill. Dr Wierda
pkpayne
in
CLL Support
5 months ago
Positive effect of diet on the whole PCa / APCa spectrum
https://www.urologytimes.com/view/plant-based-diet-demonstrates-benefits-along-spectrum-of-prostate-cancer +lots of exercise
https://www.urologytimes.com/view/plant-based-diet-demonstrates-benefits-along-spectrum-of-prostate-cancer +lots of exercise
Derf4223
in
Advanced Prostate Cancer
5 months ago
In vivo/vitro: Dickkopf-1 (DKK1) drives growth and metastases in castration-resistant prostate cancer
...does "kopf" mean head? because I could switch to call my cancer dickkopf in that case! Anyway, thanks to CRISPR we have discovered another pathway...they have discovered another pathway! https://communities.springernature.com/posts/dickkopf-1-dkk1-drives-growth-and-metastases-in-castration-resistant-prostate-cancer
...does "kopf" mean head? because I could switch to call my cancer dickkopf in that case! Anyway, thanks to CRISPR we have discovered another pathway...they have discovered another pathway! https://communities.springernature.com/posts/dickkopf-1-dkk1-drives-growth-and-metastases-in-castration-resistant-prostate-cancer
Maxone73
in
Advanced Prostate Cancer
5 months ago
Stage 4, GL 9 seeking advice
After 10 months without pain, I'm starting to have pain in my back. Orgovyx and Zytiga have appeared to keep the cancer relatively quiet until now. Next month I turn 87. I'm quite healthy, apart from Prostate cancer. I have no illusions about a cure but would like to have as many QOL days as possible
After 10 months without pain, I'm starting to have pain in my back. Orgovyx and Zytiga have appeared to keep the cancer relatively quiet until now. Next month I turn 87. I'm quite healthy, apart from Prostate cancer. I have no illusions about a cure but would like to have as many QOL days as possible
Poollover
in
Advanced Prostate Cancer
5 months ago
rash reaction to Xtandi
I was taking Xtandi and developed a rash in a few places. my oncologist insisted on getting me off of this medication.. I went to the dermatologist and he explained that he has been able to help people stay on medication even if they develop a rash. The dermatologist did a biopsy and contacted the oncologist
I was taking Xtandi and developed a rash in a few places. my oncologist insisted on getting me off of this medication.. I went to the dermatologist and he explained that he has been able to help people stay on medication even if they develop a rash. The dermatologist did a biopsy and contacted the oncologist
spolyu
in
Advanced Prostate Cancer
5 months ago
Casodex(tablet) Vs lupron(injection)
Hi allCasodex (bicalutamide) 57% for driving down PSA Lupron 87% BUT........ maybe for an individual would it be worth trying to see if casodex tablets worked better for driving down PSA instead of the lupron injection????
Hi allCasodex (bicalutamide) 57% for driving down PSA Lupron 87% BUT........ maybe for an individual would it be worth trying to see if casodex tablets worked better for driving down PSA instead of the lupron injection????
Mrtroxely
in
Advanced Prostate Cancer
5 months ago
Found a Reliable Place to Buy Enzalutamide Prostate Cancer Medication at Low Price
I found a trustworthy place to purchase Enzalutamide, a medication for prostate cancer, at a fair price. I bought it from Oddway International, an Indian pharmaceutical distributor. They were really helpful and answered all my questions patiently. The medicine arrived on time and at a price I could afford
I found a trustworthy place to purchase Enzalutamide, a medication for prostate cancer, at a fair price. I bought it from Oddway International, an Indian pharmaceutical distributor. They were really helpful and answered all my questions patiently. The medicine arrived on time and at a price I could afford
davidjroberts
in
Fight Prostate Cancer
5 months ago
QoL Tall Trees and PSA Update
https://youtu.be/TbFN3uYda_c?si=s0hWKrOIU7HRywjr https://www.nps.gov/seki/learn/nature/sherman.htm https://youtu.be/HHnA1yIO4Cc?si=AvUvLmeLel_z7NwI https://www.atlasobscura.com/articles/meet-general-sherman-the-largest-tree-in-the-world-by-volume Road trip babee, been in CA since 1976 and this is
https://youtu.be/TbFN3uYda_c?si=s0hWKrOIU7HRywjr https://www.nps.gov/seki/learn/nature/sherman.htm https://youtu.be/HHnA1yIO4Cc?si=AvUvLmeLel_z7NwI https://www.atlasobscura.com/articles/meet-general-sherman-the-largest-tree-in-the-world-by-volume Road trip babee, been in CA since 1976 and this is
dockam
in
Advanced Prostate Cancer
5 months ago
Stage 4 A Prostate cancer
My partner was diagnosed with stage 4 A prostate cancer with spread to pelvic lymph nodes. Oncologist has recommended surgery followed by radiation and hormone therapy for a good prognosis. He is 65 healthy and no symptoms. PSA was 11. Has a history of prostrate cancer. Was wondering if we should get
My partner was diagnosed with stage 4 A prostate cancer with spread to pelvic lymph nodes. Oncologist has recommended surgery followed by radiation and hormone therapy for a good prognosis. He is 65 healthy and no symptoms. PSA was 11. Has a history of prostrate cancer. Was wondering if we should get
SherryKahn
in
Advanced Prostate Cancer
5 months ago
Health Professionals Follow-up Study with initial negative prostate biopsy after 1994 were followed for incident prostate cancer until 2017
With 1851 prostate cancer cases diagnosed over 23 years, Higher BMI and lower alcohol intake tended to be associated with lower rates of localised disease. Coffee, lycopene intake and statin use tended to be associated with lower rates of lethal prostate cancer Modifiable risk factors for subsequent
With 1851 prostate cancer cases diagnosed over 23 years, Higher BMI and lower alcohol intake tended to be associated with lower rates of localised disease. Coffee, lycopene intake and statin use tended to be associated with lower rates of lethal prostate cancer Modifiable risk factors for subsequent
Graham49
in
Fight Prostate Cancer
2 months ago
2nd TACE
Hello all my husband has just had the TACE procedure on the 2nd tumour, the 1st seems to be holding its own and no cancer ‘lighting up on Scans’. We have been told this is now palliative care husband also has Alzheimer’s, is there anyone out there who is in the same boat? I am struggling with dealing
Hello all my husband has just had the TACE procedure on the 2nd tumour, the 1st seems to be holding its own and no cancer ‘lighting up on Scans’. We have been told this is now palliative care husband also has Alzheimer’s, is there anyone out there who is in the same boat? I am struggling with dealing
Campervan29
in
British Liver Trust
2 months ago
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