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Promising (maybe for PCa): World’s First Allogenic mRNA CAR-T Treatment for Solid Tumor by Ever Supreme Bio Technology, Phase 1 started.
It was published in top international medical journals and received approval from FDA in September 2023 for human
clinical
trials
. The technology has been transferred to Ever Supreme Bio Technology Co..
It was published in top international medical journals and received approval from FDA in September 2023 for human
clinical
trials
. The technology has been transferred to Ever Supreme Bio Technology Co..
Maxone73
in
Advanced Prostate Cancer
9 months ago
Romiplostim
Can taking it disqualify you from
clinical
trials
in the future?
Can taking it disqualify you from
clinical
trials
in the future?
Hidden
in
Advanced Prostate Cancer
1 year ago
Leukemia-associated macrophages, their role in the CLL Tumor Micro-environment and how they affect progression and therapy response
That's why it's so easy to kill CLL cells with in vitro testing - checking what happens to CLL cells exposed to potential drugs/supplements under a microscope, but then promising treatment candidates rarely work well in human
clinical
trials
; the CLL TME counters the treatment.
That's why it's so easy to kill CLL cells with in vitro testing - checking what happens to CLL cells exposed to potential drugs/supplements under a microscope, but then promising treatment candidates rarely work well in human
clinical
trials
; the CLL TME counters the treatment.
AussieNeil
Partner
in
CLL Support
4 months ago
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📚 Understanding the Scientific Process: A Guide for Patients
Participate in Studies:
If possible, consider participating in
clinical
trials
, which contribute to medical research and help advance knowledge.
Participate in Studies:
If possible, consider participating in
clinical
trials
, which contribute to medical research and help advance knowledge.
AnnaHU
HealthUnlocked
in
Research Opportunities
4 months ago
Provenge Complete
I am still waiting to hear from Sarah Cannon Research to review possible
clinical
trials
. In a way I feel like my Pluvicto from 10/22 to 6/23 just pissed the cancer off. Sept PSMA PET scan showed some lymph nodes resolved but new ones showing up.
I am still waiting to hear from Sarah Cannon Research to review possible
clinical
trials
. In a way I feel like my Pluvicto from 10/22 to 6/23 just pissed the cancer off. Sept PSMA PET scan showed some lymph nodes resolved but new ones showing up.
Pmann
in
Advanced Prostate Cancer
10 months ago
clinical trials and dropped off a cliff
Five years ago I joined the Astra Zeneca clinical trial of Olaparib with Zytiga, through my oncologist at Fox Chase in Philadelphia. Earlier this year A-Z ended the trial and applied for FDA approval of the combo, it does seem to help some of us. I learned that I had been taking the placebo, not the
Five years ago I joined the Astra Zeneca clinical trial of Olaparib with Zytiga, through my oncologist at Fox Chase in Philadelphia. Earlier this year A-Z ended the trial and applied for FDA approval of the combo, it does seem to help some of us. I learned that I had been taking the placebo, not the
Johnkelsey
in
Advanced Prostate Cancer
11 months ago
Alicia Morgans, MD, on PCa in Older Men – Determining frailty or fitness will help guide treatment decisions, MedPageToday, 11/27/2023
[i](See my postscript reference below) [/i]
Clinical
trials
are not exceptions to these biases and, as drug companies look to produce the best outcomes for their
clinical
trials
, patient selection (IMO) stands as #1 in that category. In her interview, Dr. Morgans' highlight that specific bias.
[i](See my postscript reference below) [/i]
Clinical
trials
are not exceptions to these biases and, as drug companies look to produce the best outcomes for their
clinical
trials
, patient selection (IMO) stands as #1 in that category. In her interview, Dr. Morgans' highlight that specific bias.
cujoe
in
Fight Prostate Cancer
10 months ago
If you have a Chat GPT 4 account, please read
https://chat.openai.com/g/g-GlKean217-patient-navigator and
Clinical
Trial Navigator, developed to help patients find appropriate
clinical
trials
https://chat.openai.com/g/g-rl6cvjdon-
clinical
-trial-navigator Please leave your comments below.
https://chat.openai.com/g/g-GlKean217-patient-navigator and
Clinical
Trial Navigator, developed to help patients find appropriate
clinical
trials
https://chat.openai.com/g/g-rl6cvjdon-
clinical
-trial-navigator Please leave your comments below.
Darryl
Partner
in
Advanced Prostate Cancer
11 months ago
Changing the name of cancer...would speed up research
Now,
clinical
trials
are almost always conducted by tumor type according to its origin, so I could find myself in a situation where the same medication could be used for different tumors, which maybe are all BRCA positive, but the experimentation is planned to be carried out sequentially (e.g. first
Now,
clinical
trials
are almost always conducted by tumor type according to its origin, so I could find myself in a situation where the same medication could be used for different tumors, which maybe are all BRCA positive, but the experimentation is planned to be carried out sequentially (e.g. first
Maxone73
in
Advanced Prostate Cancer
8 months ago
Questions for those currently on or have tried Olaparib or Rucaparib PARP inhibitors. Recently published study on Rucaparib.
From the article, [i]Specifically, the synergy demonstrated between Rucaparib and M324 in prostate cancer cell lines could have an impact on
clinical
trials
for advanced stages of this type of cancer.
From the article, [i]Specifically, the synergy demonstrated between Rucaparib and M324 in prostate cancer cell lines could have an impact on
clinical
trials
for advanced stages of this type of cancer.
mrssnappy
in
Advanced Prostate Cancer
8 months ago
Erleada or Xtandi vs Seizure Risk
I am afraid of Erleada because "patients who had any prior history of seizure or had conditions that might predispose to seizures were excluded from
clinical
trials
with apalutamide." https://www.ema.europa.eu/en/documents/rmp-summary/erleada-epar-risk-management-plan-summary_en.pdf and "Erleada is
I am afraid of Erleada because "patients who had any prior history of seizure or had conditions that might predispose to seizures were excluded from
clinical
trials
with apalutamide." https://www.ema.europa.eu/en/documents/rmp-summary/erleada-epar-risk-management-plan-summary_en.pdf and "Erleada is
vintage42
in
Advanced Prostate Cancer
8 months ago
phase 2 study for mCRPC
https://www.uclahealth.org/
clinical
-
trials
/study-two-dose-levels-vobramitamab-duocarmazine-participants For people previously treated with apalutamide, darolutamide, enzalutamide, abiraterone It’s and ADC targeting B7-H3 checkpoint https://clinicaltrials.gov/study/NCT05032040 Targets PD1
https://www.uclahealth.org/
clinical
-
trials
/study-two-dose-levels-vobramitamab-duocarmazine-participants For people previously treated with apalutamide, darolutamide, enzalutamide, abiraterone It’s and ADC targeting B7-H3 checkpoint https://clinicaltrials.gov/study/NCT05032040 Targets PD1
Maxone73
in
Advanced Prostate Cancer
1 year ago
Disease remission achieved in SLE with dual-target CAR T-cell therapy
“We are excited to progress this therapy in clinical development and plan to file [regulatory applications requesting authorization to initiate new
clinical
trials
] in the United States and China soon.”
“We are excited to progress this therapy in clinical development and plan to file [regulatory applications requesting authorization to initiate new
clinical
trials
] in the United States and China soon.”
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
3 months ago
Important from The PBC Foundation....
We are writing a letter which we would like to share with regulators about the patients’ collective views on PBC treatments and about
clinical
trials
in PBC. We need you to sign this letter and to share this letter for others to sign. We need your voice so that we can all be heard.
We are writing a letter which we would like to share with regulators about the patients’ collective views on PBC treatments and about
clinical
trials
in PBC. We need you to sign this letter and to share this letter for others to sign. We need your voice so that we can all be heard.
DonnaBoll
Administrator
in
PBC Foundation
4 months ago
"First ever successful experimental stem cell therapy for Parkinson's Disease"
10:30- what would Phase 2
clinical
trials
look like? 10:40- how will success be measured for Phase 2? 13:30- how soon could this treatment be made widely available? 14:03- for what other diseases could this treatment potentially be used for?
10:30- what would Phase 2
clinical
trials
look like? 10:40- how will success be measured for Phase 2? 13:30- how soon could this treatment be made widely available? 14:03- for what other diseases could this treatment potentially be used for?
MBAnderson
in
Cure Parkinson's
11 months ago
The TheraPb clinical trial of targeted alpha therapy for prostate cancer is running for three years with plans for up to 100 patients
The targeted alpha therapy for prostate cancer study is one of just a number of ground-breaking theranostics
trials
underway. The TheraPb
clinical
trial of targeted alpha therapy for prostate cancer is running for three years with plans for up to 100 patients to participate.
The targeted alpha therapy for prostate cancer study is one of just a number of ground-breaking theranostics
trials
underway. The TheraPb
clinical
trial of targeted alpha therapy for prostate cancer is running for three years with plans for up to 100 patients to participate.
Seasid
in
Advanced Prostate Cancer
5 months ago
Solving Restless Legs
"Compared to starting at the beginning and developing an entirely new chemical entity, we could run
clinical
trials
using these alternatives in RLS patients," said the study's first author Steven Bell, PhD, an epidemiologist with the University of Cambridge, Cambridge, England.
"Compared to starting at the beginning and developing an entirely new chemical entity, we could run
clinical
trials
using these alternatives in RLS patients," said the study's first author Steven Bell, PhD, an epidemiologist with the University of Cambridge, Cambridge, England.
thorp
in
Restless Legs Syndrome
4 months ago
And again news about clinical trials
Clinical trial tests creatine monohydrate and exercise to preserve muscle mass in prostate cancer
https://www.news-medical.net/news/20231011/Clinical-trial-tests-creatine-monohydrate-and-exercise-to-preserve-muscle-mass-in-prostate-cancer-patients.aspx (hint: been a natural bodybuilder from
Clinical trial tests creatine monohydrate and exercise to preserve muscle mass in prostate cancer
https://www.news-medical.net/news/20231011/Clinical-trial-tests-creatine-monohydrate-and-exercise-to-preserve-muscle-mass-in-prostate-cancer-patients.aspx (hint: been a natural bodybuilder from
Maxone73
in
Advanced Prostate Cancer
1 year ago
Doxorubicin pegylated liposomal
So after 3 lines, including 2
clinical
trials
, nothing was working. So I requested another biopsy. Which i got my results over the phone by my nurse. I find it hard that my cancer has changed, I am not sure if it's common. I don't see my oncologist till Thursday when I start IV chemotherapy.
So after 3 lines, including 2
clinical
trials
, nothing was working. So I requested another biopsy. Which i got my results over the phone by my nurse. I find it hard that my cancer has changed, I am not sure if it's common. I don't see my oncologist till Thursday when I start IV chemotherapy.
Cherry38
in
SHARE Metastatic Breast Cancer
10 months ago
Parkinson's Disease Pipeline, Clinical Trials Assessment, and FDA Approvals 2023 (Updated)
https://www.benzinga.com/pressreleases/23/09/ab34834243/parkinsons-disease-pipeline-
clinical
-
trials
-assessment-and-fda-approvals-2023-updated?utm_source=dlvr.it&utm_medium=twitter
https://www.benzinga.com/pressreleases/23/09/ab34834243/parkinsons-disease-pipeline-
clinical
-
trials
-assessment-and-fda-approvals-2023-updated?utm_source=dlvr.it&utm_medium=twitter
Farooqji
in
Cure Parkinson's
1 year ago
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