(hint: been a natural bodybuilder from 1991 to 2009 with (almost) 20" biceps and all...restarted working out "seriously" in 2019...for all my "career" I barely noticed any difference taking protein supplements, never noticed ANY difference with creatine when I was younger...but maybe it was bad luck!)
Novel Drug-Immunotherapy Combo Boosts Survival in Rare Prostate Cancer - Cure Today
I was at my peak strength at 27-28, at my peak as hypertrophy at around 30-33, also because I always worked out more as a weightlifter/powerlifter rather than bodybuilder. And basically most of my joints hate me for that!! Now when they ask me for some advice, the first thing I say is "don't constantly lift heavy stuff!! nothing wrong in reaching 10 reps" LOL
When I read something like this I do not feel very comfy!!
"Creatine and its analog, cyclocreatine, have been considered cancer suppressive metabolites due to their effects on suppression of subcutaneous cancer growth. Recently, emerging studies have demonstrated the promoting effect of creatine on cancer metastasis."
The balance of good evidence supports using things that help your muscle mass, energy, and strength while helping to counter fat. As you know, vegetarians are usually low on creatine. Creatine might help this population if they strength train.
I became vegan since diagnosis, so I may need to think about creatine. But honestly I have not (yet) seen a dramatic decrease of strength and resistance. Ok, I have been on ADT for 2 months only basically.
I am practically placing training equipment in every room (except bathrooms)...I have always worked out or done sports so it's something I love to do, I just hope I will determined enough!
“If your body doesn't make testosterone, you can't build muscle mass”. BS.
Of course you can. It just takes more effort to build less. Creatine’s effects are comparatively insignificant in this context. T suppression gets the blame for all the muscle loss in Pca patients but it’s only one of 4 metrics at work. The others are age, previous deconditioning and ADT induced fatigue feeding on itself.
Going into ADT we are already old. The vast majority of us are not consistently intervening by the time we are diagnosed and begin ADT. Atrophy has been gaining momentum.
These days most men in their 50’s and (especially older) either never lifted regularly or stopped lifting a long time ago. They never tire of talking about how much they used to though. When we are older and don’t lift we lose strength at an accelerating rate.
The good news is that for those who either stopped, cut back significantly or never did lift, their weakness gives them a excellent opportunity to build. Not size, strength. Building muscle size when you’re old is rare. Building strength when older is definitely possible, and the weaker you are the faster and more accessible the gains. Even on ADT.
I look at things differently. Do any of the studies say it promotes PC? If not, and there is some support for a benefit, why not take it? I need to measure my arms now at 66. Most of my contemporaries have scrawny arms and all in the medical community know the direct tie between muscle mass and longevity in general. You will never see a "gold standard" clinical study on this.
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Adding Erleada (apalutamide) to first-line ADT significantly extended survival and delayed disease progression.
Creatine
Long-term remission of prostate cancer with extensive bone metastases upon immuno- and virotherapy: A case report
