Search
Search
About
Log in
Join
Experiences with
Clinical depression
Posts
Communities
11,236 public posts
Filter results
Not about PCa, but worth checking...CRISPR in oncology phase 1-2
"A clinical trial to assess the safety and efficacy of genetically-engineered, neoantigen-specific Tumor Infiltrating Lymphocytes (TIL) in which the intracellular immune checkpoint CISH has been inhibited using CRISPR gene editing for the treatment of Gastro-Intestinal (GI) Cancer." https://www.clinicaltrials.gov
"A clinical trial to assess the safety and efficacy of genetically-engineered, neoantigen-specific Tumor Infiltrating Lymphocytes (TIL) in which the intracellular immune checkpoint CISH has been inhibited using CRISPR gene editing for the treatment of Gastro-Intestinal (GI) Cancer." https://www.clinicaltrials.gov
Maxone73
in
Advanced Prostate Cancer
5 months ago
Wait or start docetaxel?
Currently taking Nubeqa and Orgovyx but PSA doubling time is only 7 weeks and PSMA scan shows activity in abdominal lymph nodes, 2 vertebrae and 2 ribs. MO suggested DORA Clinical trial (everyone gets docetaxel, half get radium) but the head of a trial I was previously in at NIH feels that unless a CT
Currently taking Nubeqa and Orgovyx but PSA doubling time is only 7 weeks and PSMA scan shows activity in abdominal lymph nodes, 2 vertebrae and 2 ribs. MO suggested DORA Clinical trial (everyone gets docetaxel, half get radium) but the head of a trial I was previously in at NIH feels that unless a CT
AllenMarco
in
Advanced Prostate Cancer
5 months ago
Clinical trial: keep an eye on this
First results should be available by the first months of 2024. Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive
First results should be available by the first months of 2024. Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive
Maxone73
in
Advanced Prostate Cancer
5 months ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
How not to feel like a loser when success is depicted everywhere?
When you suffer from chronic depression and social anxiety, I think the best we can hope for is a dull and boring life. Just getting rid of sadness and despair might be seen as a victory. But there is no hope we can expect the exciting life full of new experiences and great opportunities depicted the
When you suffer from chronic depression and social anxiety, I think the best we can hope for is a dull and boring life. Just getting rid of sadness and despair might be seen as a victory. But there is no hope we can expect the exciting life full of new experiences and great opportunities depicted the
Sylvain-
in
Anxiety and Depression Support
1 year ago
Researchers add to existing evidence that vitamin B3 may help slow down the progression of Parkinson'
https://www.parkinsons.org.uk/news/more-research-shows-potential-benefits-vitamin-b3-parkinsons A new phase 1 clinical trial, the NR-SAFE study, has published promising signs that taking a high dose of vitamin B3 is safe, and can reduce some symptoms for people with Parkinson’s.
https://www.parkinsons.org.uk/news/more-research-shows-potential-benefits-vitamin-b3-parkinsons A new phase 1 clinical trial, the NR-SAFE study, has published promising signs that taking a high dose of vitamin B3 is safe, and can reduce some symptoms for people with Parkinson’s.
CuriousMe12
in
Cure Parkinson's
5 months ago
Cancer causation -- inflammation and statistics
https://www.newyorker.com/magazine/2023/12/18/all-the-carcinogens-we-cannot-see Those of us whose cancer is quiet don't want to wake it up, but nobody knows for sure what to do (or not do). This article provides some food for thought and offers the opportunity for us to revisit our views about the
https://www.newyorker.com/magazine/2023/12/18/all-the-carcinogens-we-cannot-see Those of us whose cancer is quiet don't want to wake it up, but nobody knows for sure what to do (or not do). This article provides some food for thought and offers the opportunity for us to revisit our views about the
mistersafety
in
Advanced Prostate Cancer
5 months ago
Restless Leg Syndrome, neuromodulation..
Treatment was well tolerated, and no adverse events were reported. Our case series shows a potential role for self-administered taVNS in patients with severe pharmacoresistant RLS. Hartley S, Bao G, Russo A, Zagdoun M, Chevallier S, Lofaso F, Leotard A, Azabou E. Self-administered non-invasive vagus
Treatment was well tolerated, and no adverse events were reported. Our case series shows a potential role for self-administered taVNS in patients with severe pharmacoresistant RLS. Hartley S, Bao G, Russo A, Zagdoun M, Chevallier S, Lofaso F, Leotard A, Azabou E. Self-administered non-invasive vagus
House2
in
Restless Legs Syndrome
5 months ago
Old new approach! MYC inhibitors
myc is a gene present in most kinds of cancer, something has reached clinical trials at last! https://www.peptomyc.com/results-revealed-from-phase-i-clinical-trial-of-the-first-drug-to-successfully-inhibit-the-myc-gene-which-drives-many-common-cancers/
myc is a gene present in most kinds of cancer, something has reached clinical trials at last! https://www.peptomyc.com/results-revealed-from-phase-i-clinical-trial-of-the-first-drug-to-successfully-inhibit-the-myc-gene-which-drives-many-common-cancers/
Maxone73
in
Advanced Prostate Cancer
5 months ago
Advances in solid tumors: finnish clinical trial
Interesting results are coming! Bexmarilimab seems to be able to improve immunotherapy. It was not yet tested on prostate cancer, but it's already commercially used to treat blood malignacies. As single agent: https://www.faron.com/our-science/clinical-trials/matins "Latest data showed a three-fold
Interesting results are coming! Bexmarilimab seems to be able to improve immunotherapy. It was not yet tested on prostate cancer, but it's already commercially used to treat blood malignacies. As single agent: https://www.faron.com/our-science/clinical-trials/matins "Latest data showed a three-fold
Maxone73
in
Advanced Prostate Cancer
5 months ago
Need to Change Treatment
So I have progression after two years on Ibrance and Letrozole. I have an opportunity to participate in a clinical trial in my town in which I would be randomly assigned to Giredestrant, a promising oral SERD (monotherapy) or both Giredestrant with a new Pikc3a drug. My standard of care option would
So I have progression after two years on Ibrance and Letrozole. I have an opportunity to participate in a clinical trial in my town in which I would be randomly assigned to Giredestrant, a promising oral SERD (monotherapy) or both Giredestrant with a new Pikc3a drug. My standard of care option would
Trissh
in
SHARE Metastatic Breast Cancer
5 months ago
Intense jaw pain (pt.2)
Three months ago my husband developed intense right jaw pain. After multiple scans showing "something" (thankfully no PSMA activity) he had a surgical bone biopsy 11/29. Two days ago we received the pathology report but have not been able to speak with the Dr. to help us understand it. The good news
Three months ago my husband developed intense right jaw pain. After multiple scans showing "something" (thankfully no PSMA activity) he had a surgical bone biopsy 11/29. Two days ago we received the pathology report but have not been able to speak with the Dr. to help us understand it. The good news
Decktime
in
Advanced Prostate Cancer
5 months ago
Happy Friday HU
Please feel free to show us your projects and photos, I'd love to see them. I will be out of my house for a few hours after I post this thread, but I'll get back here later. I have noticed a few artists sharing their work here, and although my Muse seems to be hiding from me this past winter, I can't
Please feel free to show us your projects and photos, I'd love to see them. I will be out of my house for a few hours after I post this thread, but I'll get back here later. I have noticed a few artists sharing their work here, and although my Muse seems to be hiding from me this past winter, I can't
Boston001
in
Anxiety and Depression Support
1 year ago
ST-067 in combination with pembrolizumab clinical trial
https://www.moffitt.org/clinical-trials-and-studies/clinical-trial-21340/
https://www.moffitt.org/clinical-trials-and-studies/clinical-trial-21340/
Maxone73
in
Advanced Prostate Cancer
5 months ago
Anyone can access this article?
"As Bertagnolli steps in, NIH and FDA reenvision clinical trials and evidence generation"..it could be the modernization of clinical trials I have been waiting for The only Monica Bertagnolli I knew was a tough girl, I want to see if this Monica is also such a tough cookie https://cancerletter.com
"As Bertagnolli steps in, NIH and FDA reenvision clinical trials and evidence generation"..it could be the modernization of clinical trials I have been waiting for The only Monica Bertagnolli I knew was a tough girl, I want to see if this Monica is also such a tough cookie https://cancerletter.com
Maxone73
in
Advanced Prostate Cancer
5 months ago
Why do I feel so depressed so much
I can go a couple of days just about coping and then I fold and feel I can't take no more. I do have a lot of physical ailments to cope with as well and no family to talk to as they have passed away. I just don't know how to keep the anxiety and depression away and feel there's only the cowards way out
I can go a couple of days just about coping and then I fold and feel I can't take no more. I do have a lot of physical ailments to cope with as well and no family to talk to as they have passed away. I just don't know how to keep the anxiety and depression away and feel there's only the cowards way out
jonnylongton
in
Anxiety and Depression Support
1 year ago
new clinical trial Risvodetinib (IkT-148009)
The 201 Clinical Trial For Patients With Untreated Parkinson’s Disease The 201 Clinical Trial is a trial that will explore whether a novel drug, Risvodetinib (IkT-148009), can slow or halt progression of Parkinson’s disease. The trial will also evaluate whether Risvodetinib (IkT-148009) can partially
The 201 Clinical Trial For Patients With Untreated Parkinson’s Disease The 201 Clinical Trial is a trial that will explore whether a novel drug, Risvodetinib (IkT-148009), can slow or halt progression of Parkinson’s disease. The trial will also evaluate whether Risvodetinib (IkT-148009) can partially
Boscoejean
in
Cure Parkinson's
5 months ago
depression
I don’t know how long it lasted but it was replaced with
clinical
depression
. when first receiving counselling, all I could do was sob continually and blurt out that I didn’t know who I was anymore.
I don’t know how long it lasted but it was replaced with
clinical
depression
. when first receiving counselling, all I could do was sob continually and blurt out that I didn’t know who I was anymore.
Steveau
in
Headway
4 months ago
first U.S. patients dosed in expanded Phase 1b clinical trial of CB307 for patients with mCRPC
one step at a time….immune therapy for prostate cancer is becoming hotter! https://finance.yahoo.com/news/crescendo-biologics-announces-first-u-120000112.html
one step at a time….immune therapy for prostate cancer is becoming hotter! https://finance.yahoo.com/news/crescendo-biologics-announces-first-u-120000112.html
Maxone73
in
Advanced Prostate Cancer
5 months ago
Vitamin D and Anemia: Insights into an Emerging Association
Found an interesting study. The conclusion sold it for me. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659411/ CONCLUSION Vitamin D is associated with anemia in various study populations and recent evidence suggests that the association may differ by race and is likely specific to anemia of inflammation
Found an interesting study. The conclusion sold it for me. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659411/ CONCLUSION Vitamin D is associated with anemia in various study populations and recent evidence suggests that the association may differ by race and is likely specific to anemia of inflammation
WideBody
in
Restless Legs Syndrome
5 months ago
New to this
I’m Jo, age 66, living in Chicago. I believe I have early stage PD. I haven’t been diagnosed yet have been acting out dreams for at least five years, and my right arm doesn’t swing. I’m hoping to get diagnosed soon so I can participate in a clinical trial.
I’m Jo, age 66, living in Chicago. I believe I have early stage PD. I haven’t been diagnosed yet have been acting out dreams for at least five years, and my right arm doesn’t swing. I’m hoping to get diagnosed soon so I can participate in a clinical trial.
Jomaxx
in
Cure Parkinson's
5 months ago
1
...
28
29
30
...
100
Next page
10
20
30
40
50
60
70
80
90
100
Filter results
Clear filters
Posted in
All communities
Anxiety and Depression Support
2612 results
Advanced Prostate Cancer
1264 results
Mental Health Support
740 results
View top 10 communities
Sort by
Most Relevant
Newest