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Photopharmics kickstarts phototherapy trial for Parkinson’s disease
The US Food and Drug Administration (FDA)-approved device targets photoreceptors in the eye responsible for circadian signalling. Research has shown that Parkinson’s disease can damage the retina and impact the circadian system leading to symptoms such as trouble sleeping, cognition, depression, and
The US Food and Drug Administration (FDA)-approved device targets photoreceptors in the eye responsible for circadian signalling. Research has shown that Parkinson’s disease can damage the retina and impact the circadian system leading to symptoms such as trouble sleeping, cognition, depression, and
Farooqji
in
Cure Parkinson's
29 days ago
Anecdotal, but running could boost immunity
I am reading a lovely book of essays called These Precious Days by Ann Patchett. In the title essay a friend of the author is taking part in a clinical trial, having chemotherapy for pancreatic cancer. As you will know, Chemo destroys white blood cells which provide immunity, so you have to have a high
I am reading a lovely book of essays called These Precious Days by Ann Patchett. In the title essay a friend of the author is taking part in a clinical trial, having chemotherapy for pancreatic cancer. As you will know, Chemo destroys white blood cells which provide immunity, so you have to have a high
PeggySusi
Graduate
in
Couch to 5K
30 days ago
Anecdotal, but indicates that exercise boosts immunity
I am reading a lovely book of essays called These Precious Days by Ann Patchett. In the title essay a friend of the author is taking part in a clinical trial, having chemotherapy for pancreatic cancer. As you will know, Chemo destroys white blood cells which provide immunity, so you have to have a
I am reading a lovely book of essays called These Precious Days by Ann Patchett. In the title essay a friend of the author is taking part in a clinical trial, having chemotherapy for pancreatic cancer. As you will know, Chemo destroys white blood cells which provide immunity, so you have to have a
PeggySusi
in
Active 10
1 month ago
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Dutasteride reduces PSA by 40% over 6 months
This companion chart from data reported in Moore (2017) compares PSA, at baseline and at 6 months, comparing placebo to Dutasteride. This was a randomized, double-blind, placebo-controlled clinical trial. The cohort included Low and Intermediate Risk men, GS-6-7, baseline PSA = 6-7, median age 64 y.o
This companion chart from data reported in Moore (2017) compares PSA, at baseline and at 6 months, comparing placebo to Dutasteride. This was a randomized, double-blind, placebo-controlled clinical trial. The cohort included Low and Intermediate Risk men, GS-6-7, baseline PSA = 6-7, median age 64 y.o
janebob99
in
Prostate Cancer Network
1 month ago
Dutasteride Reduces Tumor Volume by 30% after 6 months.
This chart compares prostate cancer tumor volume measured by MRI, at baseline and at 6 months, comparing placebo to Dutasteride. This was a randomized, double-blind, placebo-controlled clinical trial. The cohort included Low and Intermediate Risk men, GS-6-7, baseline PSA = 6-7, median age 64 y.o,
This chart compares prostate cancer tumor volume measured by MRI, at baseline and at 6 months, comparing placebo to Dutasteride. This was a randomized, double-blind, placebo-controlled clinical trial. The cohort included Low and Intermediate Risk men, GS-6-7, baseline PSA = 6-7, median age 64 y.o,
janebob99
in
Prostate Cancer Network
1 month ago
Bowel irrigation (Not "colonic irrigation")
I have obstructed defecation (anismus) which has not responded to biofeedback etc. The next step is at home bowel irrigation and I am just waiting for an appointment with the bowel nurse to issue me with the equipment. It would be helpful to hear of anyone`s experience with this. I don`t know which
I have obstructed defecation (anismus) which has not responded to biofeedback etc. The next step is at home bowel irrigation and I am just waiting for an appointment with the bowel nurse to issue me with the equipment. It would be helpful to hear of anyone`s experience with this. I don`t know which
janke
in
IBS Network
1 year ago
unanswered questions
I'm excited to be leaving for The International PBC Summit in Edinburgh the end of next week. I'll be bringing back as much information to you as I can about research being done for the cause of PBC, itching and fatigue. All of these issues have impacted all of our lives to some degree. Many of us have
I'm excited to be leaving for The International PBC Summit in Edinburgh the end of next week. I'll be bringing back as much information to you as I can about research being done for the cause of PBC, itching and fatigue. All of these issues have impacted all of our lives to some degree. Many of us have
DonnaBoll
Administrator
in
PBC Foundation
1 month ago
Falling platelet counts after achieving Undetectable Minimal Residual Diseaese
Hello folks I completed a course of Venetoclax & Obinituzumab (Gazyva) last March, and happily achieved UMRD (undetectable minimal residual disease). I'm part of a clinical trial, which stopped treatment once I reached UMRD (with a minimum of 6-9 months of treatment); I was treated for 9 months. Have
Hello folks I completed a course of Venetoclax & Obinituzumab (Gazyva) last March, and happily achieved UMRD (undetectable minimal residual disease). I'm part of a clinical trial, which stopped treatment once I reached UMRD (with a minimum of 6-9 months of treatment); I was treated for 9 months. Have
DinosaurDad
in
CLL Support
1 month ago
OCD Institute - Houston
My adult son was recently referred to the OCD Institute in Houston for residential treatment. Has anyone had success there or can anyone share their experience there? He has been in outpatient treatment since the beginning of January and so far it is not working well. We are looking for any help we can
My adult son was recently referred to the OCD Institute in Houston for residential treatment. Has anyone had success there or can anyone share their experience there? He has been in outpatient treatment since the beginning of January and so far it is not working well. We are looking for any help we can
BrooksideBliss
in
My OCD Community
1 month ago
slow release liothyronine
Like many people on here I miss the wise opinion and knowledge of Diogenes enormously. I know he was working on the formulation of a slow release liothyronine which was in clinical trial. Does anyone have an update on this? is it any closer? In the meantime I am tempted to try sustained release compounded
Like many people on here I miss the wise opinion and knowledge of Diogenes enormously. I know he was working on the formulation of a slow release liothyronine which was in clinical trial. Does anyone have an update on this? is it any closer? In the meantime I am tempted to try sustained release compounded
Mollyfan
in
Thyroid UK
1 month ago
Does Buspirone take time to work
I moved the actual question to the front. Lol. Too much rant. My question is: If any of you take buspirone, what were You told, please, as far as how it works? This is kind of a "poll" for my arsenal, not something I intend to use as medical advice. ***Were you told it takes awhile to work, and
I moved the actual question to the front. Lol. Too much rant. My question is: If any of you take buspirone, what were You told, please, as far as how it works? This is kind of a "poll" for my arsenal, not something I intend to use as medical advice. ***Were you told it takes awhile to work, and
Hidden
in
Anxiety and Depression Support
1 year ago
Smell Training (Olfactory Training)
Smell Training (Olfactory Training)
March 18, 2024
This post is about Smell Training and is building on an earlier HU post “Olfactory enrichment improves olfactory ability in humans with olfactory loss due to Parkinson’s”
https://healthunlocked.com/cure-parkinsons/posts/150588869/olfactory-enrichment-improves-olfactory-ability-in-humans-with-olfactory-loss-due-to-parkinson-s
Smell Training (Olfactory Training)
March 18, 2024
This post is about Smell Training and is building on an earlier HU post “Olfactory enrichment improves olfactory ability in humans with olfactory loss due to Parkinson’s”
https://healthunlocked.com/cure-parkinsons/posts/150588869/olfactory-enrichment-improves-olfactory-ability-in-humans-with-olfactory-loss-due-to-parkinson-s
Bolt_Upright
in
Cure Parkinson's
1 month ago
Seeking anyone familiar with aggressive small cell neuroendocrine prostate cancer and/or with lurbinectedin as 2nd line chemotherapy.
A needle biopsy Oct 15, 2023 revealed that at least some of my metastatic prostate cancer in a lymph node had mutated to an aggressive small cell neuroendocrine prostate cancer. (notable for CDK N1B, RB1, Tp53 mutations. MSS, TMB low) I had 4 cycles of carboplatin/etoposide chemotherapy, which ended
A needle biopsy Oct 15, 2023 revealed that at least some of my metastatic prostate cancer in a lymph node had mutated to an aggressive small cell neuroendocrine prostate cancer. (notable for CDK N1B, RB1, Tp53 mutations. MSS, TMB low) I had 4 cycles of carboplatin/etoposide chemotherapy, which ended
silver5
in
Advanced Prostate Cancer
1 month ago
Weighing the pros and possible risks of treatment holiday.
I am looking for reliable articles (not too scientific please). We will be discussing w oncologist this week and again with his clinical trial people next month. My husband's only treatment has been 1st & 2nd generation hormone therapy (Eligard & Darolutamide) for 20 months. He reached >.1 nadar
I am looking for reliable articles (not too scientific please). We will be discussing w oncologist this week and again with his clinical trial people next month. My husband's only treatment has been 1st & 2nd generation hormone therapy (Eligard & Darolutamide) for 20 months. He reached >.1 nadar
Decktime
in
Advanced Prostate Cancer
1 month ago
Webinar:Do magnifying intraocular lenses work for people with macular disease?
Magnifying lenses, which are implanted are available to help those with macular disease see better. But, no trials have been done to prove how useful they are or who they are most suitable for. Dr Julie Silvestri from Royal Hospitals, Belfast, will be joining us for our first webinar of the month to
Magnifying lenses, which are implanted are available to help those with macular disease see better. But, no trials have been done to prove how useful they are or who they are most suitable for. Dr Julie Silvestri from Royal Hospitals, Belfast, will be joining us for our first webinar of the month to
Carol_MacularSociety
Partner
in
Macular Society
1 month ago
Husbands depression, adha, has ruined early Christmas with family
Hi, this is my first post, sorry for the brain dump but I just needed to see if anyone can relate, offer advice or just support.My husband has
clinical
depression
and adhd. He's been taking antidepressants for 4 years, medical cannabis for 1-2year and adhd medicine for around 1 year.
Hi, this is my first post, sorry for the brain dump but I just needed to see if anyone can relate, offer advice or just support.My husband has
clinical
depression
and adhd. He's been taking antidepressants for 4 years, medical cannabis for 1-2year and adhd medicine for around 1 year.
Hidden
in
Anxiety and Depression Support
5 months ago
Chemo or clinical trial?
Am scheduled for bone biopsy of met(s) from my hip tomorrow. Stopped Pluvicto after #3 due to rising PSA and progression. Hoping to get next gen. sequencing from biopsy sample and (maybe) functional testing. But, it's going to take some time to get results and I feel I can't wait. Pain has been getting
Am scheduled for bone biopsy of met(s) from my hip tomorrow. Stopped Pluvicto after #3 due to rising PSA and progression. Hoping to get next gen. sequencing from biopsy sample and (maybe) functional testing. But, it's going to take some time to get results and I feel I can't wait. Pain has been getting
rsgdmd
in
Advanced Prostate Cancer
1 month ago
Saxon clinical trial
Hello all, I was recently enrolled in the Saxon clinical trial combining Xofigo with SBRT. Is anyone else in that trial? Diagnosed with prostate Cancer July 2014, Gleason 7 (4+3) in 6 of 12 . After Radiation treatments my PSA was undetectable until July 2019. It rose to 3.9 in January 2020
Hello all, I was recently enrolled in the Saxon clinical trial combining Xofigo with SBRT. Is anyone else in that trial? Diagnosed with prostate Cancer July 2014, Gleason 7 (4+3) in 6 of 12 . After Radiation treatments my PSA was undetectable until July 2019. It rose to 3.9 in January 2020
58Willys
in
Advanced Prostate Cancer
1 month ago
The Importance of Peer-Review
Even renowned oncologists can fall in love with their data. It takes the impartial analysis of an outside expert to see the confirmation bias that may be blinding the lead investigator of a Phase 3 clinical trial. Although Phase 3 trials are Level 1 evidence, they still must be graded by outside experts
Even renowned oncologists can fall in love with their data. It takes the impartial analysis of an outside expert to see the confirmation bias that may be blinding the lead investigator of a Phase 3 clinical trial. Although Phase 3 trials are Level 1 evidence, they still must be graded by outside experts
Tall_Allen
in
Advanced Prostate Cancer
1 month ago
How long on Entresto
I would like to ask what’s the longest anyone on this post has been on Entresto. My cardiologist has patients who started on it back when the clinical trials began in 2015 and doing quite well.
I would like to ask what’s the longest anyone on this post has been on Entresto. My cardiologist has patients who started on it back when the clinical trials began in 2015 and doing quite well.
am1875
in
British Heart Foundation
1 month ago
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