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Why is it critical to achieve a deep molecular response ?
»Reaching a Deep Molecular Remission is now considered a goal of therapy by many clinicians. The importance of a DMR for patients aiming to achieve Treatment Free Remission is recognized by the inclusion of DMR as an endpoint measure in clinical trials. Additionally, TFR is increasingly acknowledged
»Reaching a Deep Molecular Remission is now considered a goal of therapy by many clinicians. The importance of a DMR for patients aiming to achieve Treatment Free Remission is recognized by the inclusion of DMR as an endpoint measure in clinical trials. Additionally, TFR is increasingly acknowledged
Manouche
in
MPN Voice
2 years ago
Pluvicto advisable for low volume disease? A recent PSA scan showed one tumor in my spine and one and a rib but also castrate resistant
I’ve been on Orgovyx for the last 15 months and three months ago my PSA started to rise and is now at .44. I’ve been hearing rumors about clinical trials for low volume disease but don’t know anything more about it. Can anyone recommend a clinic in Europe that might be experimenting on this level?
I’ve been on Orgovyx for the last 15 months and three months ago my PSA started to rise and is now at .44. I’ve been hearing rumors about clinical trials for low volume disease but don’t know anything more about it. Can anyone recommend a clinic in Europe that might be experimenting on this level?
SViking
in
Advanced Prostate Cancer
2 years ago
Injured and feeling guilty blowing vaca. time
Hi - so I ended up dislocating my hip (artificial) at the start of vaca. week. I had it reduced and am now in a leg brace on 24/7 hip dislocation precautions, i.e. no bending at the waist, can't bring my hip higher than my knee, etc. I feel so guilty that we can't really go anywhere, e.g., beach, since
Hi - so I ended up dislocating my hip (artificial) at the start of vaca. week. I had it reduced and am now in a leg brace on 24/7 hip dislocation precautions, i.e. no bending at the waist, can't bring my hip higher than my knee, etc. I feel so guilty that we can't really go anywhere, e.g., beach, since
Perseus0396
in
Anxiety and Depression Support
2 years ago
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Any one know about new immune response clinical trials for metastatic prostate cancer?
inhave a friend that had stage 4 prostate cancer he was treated with surgery and chemo but it has returned and is aggressive and spread. His PSA also went up, Trying to find out about the new trials that are aimed at him
inhave a friend that had stage 4 prostate cancer he was treated with surgery and chemo but it has returned and is aggressive and spread. His PSA also went up, Trying to find out about the new trials that are aimed at him
Zigzagzig
in
Prostate Cancer And Gay Men
2 years ago
Splenomegaly in Polycythemia Vera: Its Clinical Significance and its Relation to Symptoms
Background: Splenomegaly (SPML) in PV has been considered a diagnostic hallmark, associated with symptoms, affected clinical trial design, and influenced governmental approval of ropeginterferon α-2b. Whether SPML affects myelofibrosis-free and overall survival (MFS and OS) is unknown. Because of uncertainty
Background: Splenomegaly (SPML) in PV has been considered a diagnostic hallmark, associated with symptoms, affected clinical trial design, and influenced governmental approval of ropeginterferon α-2b. Whether SPML affects myelofibrosis-free and overall survival (MFS and OS) is unknown. Because of uncertainty
Manouche
in
MPN Voice
2 years ago
Waters broken - 33 + 4 weeks
I’m 33+4 weeks pregnant and my waters broke today at 2am. I am feeling lots of pressure down below and lots of niggly pains - some contractions too but not really that frequent. How long did you go into labour after your waters broke? I do have Polyhydramnios so there is a lot of fluid!!! It’s my second
I’m 33+4 weeks pregnant and my waters broke today at 2am. I am feeling lots of pressure down below and lots of niggly pains - some contractions too but not really that frequent. How long did you go into labour after your waters broke? I do have Polyhydramnios so there is a lot of fluid!!! It’s my second
Laurahickman33
in
Pregnancy and Parenting Support
2 years ago
Zytiga failure after 4 years what now
Hi Diagnosed in 2016 had SBRT . Life good 2 years and found 1 met in lung . Did Lupron/zytiga PSA drop to under .1 for 2 years. Requested a vacation . 15 months later PSA rises do PSMA . One met on vertibrae only . Did SBRT and doc said let’s do lung met at the same time even though it’s not showing
Hi Diagnosed in 2016 had SBRT . Life good 2 years and found 1 met in lung . Did Lupron/zytiga PSA drop to under .1 for 2 years. Requested a vacation . 15 months later PSA rises do PSMA . One met on vertibrae only . Did SBRT and doc said let’s do lung met at the same time even though it’s not showing
Db999
in
Advanced Prostate Cancer
2 years ago
Support
Hi all, Looking for support. I am about 8 weeks in after acute postpartum psychosis which I was hospitalised for and suffering with low points and anxiety. I had a traumatic birth and a very premature baby who is now doing really well thankfully. I am on medication for the psychosis but I still feel
Hi all, Looking for support. I am about 8 weeks in after acute postpartum psychosis which I was hospitalised for and suffering with low points and anxiety. I had a traumatic birth and a very premature baby who is now doing really well thankfully. I am on medication for the psychosis but I still feel
kitty12345
in
Action on Postpartum Psychosis
2 years ago
Zhittya announces "Safe and Effective" treatment for PD
I know many of us (including myself) are skeptical about this company (they charge 50 thousand if you want to be a 'volunteer test subject'). I don't begrudge anyone an honest living. So let's just hope they come up with some good results to help us. --------------------------------- "FGF-1, Zhittya
I know many of us (including myself) are skeptical about this company (they charge 50 thousand if you want to be a 'volunteer test subject'). I don't begrudge anyone an honest living. So let's just hope they come up with some good results to help us. --------------------------------- "FGF-1, Zhittya
PDWarrior1900
in
Cure Parkinson's
2 years ago
2022 Emerging Leaders Prize Awarded to 3 Researchers in UK
Awardees received a total of £220K funded by the will of scientist with the disease by Patricia Valerio, PhD | December 8, 2022 The Medical Research Foundation has awarded its sixth Emerging Leaders Prize to three lupus researchers in the U.K. The scientists received a total of £220,000 (around
Awardees received a total of £220K funded by the will of scientist with the disease by Patricia Valerio, PhD | December 8, 2022 The Medical Research Foundation has awarded its sixth Emerging Leaders Prize to three lupus researchers in the U.K. The scientists received a total of £220,000 (around
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
Scientists using cells to hopefully grow "mini livers"
Just a super interesting article on a clinical trial that is using cells from donated livers to see if ectopic mini livers can be grown in human lymph nodes that would provide additional liver function in people with ESLD. 2027 is not too far away! Regenerative medicine is advancing yall! Exciting and
Just a super interesting article on a clinical trial that is using cells from donated livers to see if ectopic mini livers can be grown in human lymph nodes that would provide additional liver function in people with ESLD. 2027 is not too far away! Regenerative medicine is advancing yall! Exciting and
muffins7
in
British Liver Trust
2 years ago
Resveratrol and ET
Hi everyone, I’m wondering whether anyone has tried the natural phenol, Resveratrol, to help their platelet reduction? I’m calr positive ET on Hydrea which I hate taking for its toxic effect . My haematologist just continues to increase the dose to try to suppress rising platelet count. However I have
Hi everyone, I’m wondering whether anyone has tried the natural phenol, Resveratrol, to help their platelet reduction? I’m calr positive ET on Hydrea which I hate taking for its toxic effect . My haematologist just continues to increase the dose to try to suppress rising platelet count. However I have
myllo
in
MPN Voice
2 years ago
Severe Anxiety, Loneliness and Depression Support
Hi everyone, Hope you're all well. I'm wondering if there are any support groups here or people who are interested in starting one for folks with anxiety and loneliness. I'm really deeply struggling right now with feeling alone even though I have a supportive small family. I'm an only child and I'm
Hi everyone, Hope you're all well. I'm wondering if there are any support groups here or people who are interested in starting one for folks with anxiety and loneliness. I'm really deeply struggling right now with feeling alone even though I have a supportive small family. I'm an only child and I'm
Ramon123
in
Anxiety and Depression Support
2 years ago
ART Effect of Vitamin D3 Supplements on Development of Advanced Cancer
Effect of Vitamin D3 Supplements on Development of Advanced Cancer ...randomized clinical trial with
25 871 patients
, from November 1, 2011, to December 31, 2017.
...supplementation with vitamin D3 reduced the incidence of advanced (metastatic or fatal) cancer in the overall cohort,
Effect of Vitamin D3 Supplements on Development of Advanced Cancer ...randomized clinical trial with
25 871 patients
, from November 1, 2011, to December 31, 2017.
...supplementation with vitamin D3 reduced the incidence of advanced (metastatic or fatal) cancer in the overall cohort,
RMontana
in
Active Surveillance - Prostate Cancer
2 years ago
Potential New Treatment for “Brain Fog” in Long COVID Patients
Although brain fog in thyroid patients has often been dismissed by medics (whether not understood, not believed, or some other reason, I cannot say). However, it is coming through as a recognised symptom of Long Covid. Hopefully, even if the actual detailed causes are slightly or radically different
Although brain fog in thyroid patients has often been dismissed by medics (whether not understood, not believed, or some other reason, I cannot say). However, it is coming through as a recognised symptom of Long Covid. Hopefully, even if the actual detailed causes are slightly or radically different
helvella
Thyroid UK
in
Thyroid UK
2 years ago
phase 1 clinical trials at Royal Marsden — anyone has experience?
hi all .. I’ve been offered either a phase 1 clinical trial or a phase 3 clinical trial at the Royal Marsden . The difference is that in phase 1 , a possible new drug is having its first tests but in phase 3 , the drug has been shown to work in some patients and may move to being approved. however ,
hi all .. I’ve been offered either a phase 1 clinical trial or a phase 3 clinical trial at the Royal Marsden . The difference is that in phase 1 , a possible new drug is having its first tests but in phase 3 , the drug has been shown to work in some patients and may move to being approved. however ,
Lookingahead
in
My Ovacome
2 years ago
Isolated
Dear all, Im sorry to post again,but I feel so isolated. I've found the summer holidays and the last month (without medication)really hard and isolating. I just feel like nobody around me understands. I think my husband is fed up of hearing how I feel and since I'm 18months postpartum just
Dear all, Im sorry to post again,but I feel so isolated. I've found the summer holidays and the last month (without medication)really hard and isolating. I just feel like nobody around me understands. I think my husband is fed up of hearing how I feel and since I'm 18months postpartum just
Dolly292
in
Action on Postpartum Psychosis
2 years ago
After 11 years, dad has started chemo for the first time
Hey all, dad was diagnosed in Feb 2012 (removed prostate right away), metastasized to the coccyx in 2019. Been on Zoladex (for life), Zytiga, Xtandi, etc. Now that his PSA is very slowly increasing (been going up since 2019 from below 0.30 to now at 2.0+), his oncologist recommended we enroll him in
Hey all, dad was diagnosed in Feb 2012 (removed prostate right away), metastasized to the coccyx in 2019. Been on Zoladex (for life), Zytiga, Xtandi, etc. Now that his PSA is very slowly increasing (been going up since 2019 from below 0.30 to now at 2.0+), his oncologist recommended we enroll him in
PHnerd
in
Advanced Prostate Cancer
2 years ago
This helps you and us
Dear Particpants of Malecare's Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge
Dear Particpants of Malecare's Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge
Darryl
Partner
in
Prostate Cancer Caregivers
2 years ago
This helps you and us
Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge information, and innovative research. Indeed, no other prostate cancer nonprofit has produced more peer-reviewed papers and patented medical innovations
Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge information, and innovative research. Indeed, no other prostate cancer nonprofit has produced more peer-reviewed papers and patented medical innovations
Darryl
Partner
in
Prostate Cancer And Gay Men
2 years ago
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