OsteoDex: for mCRPC bone metastasis!

[Maxone73]

clinical trials are going well, and results are better than with zometa or Denosumab!

mb.cision.com/Main/11652/38...

[DrawingSnowmen]

Here's info from the phase 2 trial:

sciencedirect.com/science/a...

>The median time to progression (mTTP) of B-ALP, S-P1NP and S-PSA are summarised in Table 2. mTTP of metastases in bone, assessed 2 weeks after the last dose (maximum doses: 10): 19.7 weeks, no statistically significant differences between study arms*. mTTP of soft tissue metastases, assessed 2 weeks after the last dose (maximum doses: 10): 21.6 weeks, no statistically significant differences between study arms.

All doses were well tolerated and demonstrated a benign safety profile. No jaw osteonecrosis was reported. <

Interesting that it apparently also had an effect on soft tissue metastases.

*All study arms had treatment, there was no placebo controlled arm.

[Maxone73 in reply to DrawingSnowmen]

It looks promising!

[DrawingSnowmen in reply to Maxone73]

Here's additional info, looking forward to phase 3!

dextechmedical.com/en/candi...

[Maxone73 in reply to DrawingSnowmen]

I am trying to focus on all the connections I may have in Sweden!

[Maxone73 in reply to DrawingSnowmen]

what worries me is that phase 2 should be over by at least 3 years now

[DrawingSnowmen in reply to Maxone73]

It kind of sounds like they're filing for a patent to attract a "major partner" so they can afford the phase 3 trial.

[Maxone73 in reply to DrawingSnowmen]

I contacted them to ask...and to offer a free modern website for their company....it's my job and I cannot stand something so "late nineties" for a pharmatech company 😆

[j-o-h-n]

Geez if you can't stand something so "late nineties".......... I guess I'm a fricking goner since I'm a "late thirties".....

Good Luck, Good Health and Good Humor.

j-o-h-n

[Maxone73 in reply to j-o-h-n]

That site is old, you are vintage…it’s a complete different story!

[j-o-h-n in reply to Maxone73]

You know, nuttin like a vintage whine.......

Good Luck, Good Health and Good Humor.

j-o-h-n