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What is the most accurate Test/Scan to do when one has Metastatic Castration-Sensitive Prostate Cancer?
Hello everyone, I have good news to report but I am now a bit confused about my prognosis. I need your help and your valuable expertise. I was diagnosed with PC (Gleason score 9) in Nov. 2019. I have been on Eligard/Lupron + Erleada for the past 12 months my PSA has been undetected (<0.1) for the last
Hello everyone, I have good news to report but I am now a bit confused about my prognosis. I need your help and your valuable expertise. I was diagnosed with PC (Gleason score 9) in Nov. 2019. I have been on Eligard/Lupron + Erleada for the past 12 months my PSA has been undetected (<0.1) for the last
Pcnmyy
in
Advanced Prostate Cancer
4 years ago
Can anyone answer my question?
What happens to healthy prostate cell when Testosterone goes below
castration
level? Do they still produce PSA? How they are impacted by lack of Testosterone? I have done a great deal of searching without getting a satisfactory answer.
What happens to healthy prostate cell when Testosterone goes below
castration
level? Do they still produce PSA? How they are impacted by lack of Testosterone? I have done a great deal of searching without getting a satisfactory answer.
dac500
in
Advanced Prostate Cancer
4 years ago
Metastatic Prostate Cancer
https://ger.bioconus.com/emerging-therapeutic-approaches-management-metastatic-
castration
-resistant-prostate-cancer-459030 I found an interesting link in German about the latest developments in the treatment of metastatic prostate cancer. All the best. Good health!
https://ger.bioconus.com/emerging-therapeutic-approaches-management-metastatic-
castration
-resistant-prostate-cancer-459030 I found an interesting link in German about the latest developments in the treatment of metastatic prostate cancer. All the best. Good health!
Marius1968
in
Advanced Prostate Cancer
4 years ago
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Would it work when we go back to the old treatment again? Your input would be appreciated.
After all other treatments like zytiga, xstandi, etc. are
castration
-resistant, would it work when go back to lupron and casodex again? Thanks.
After all other treatments like zytiga, xstandi, etc. are
castration
-resistant, would it work when go back to lupron and casodex again? Thanks.
markoch26
in
Advanced Prostate Cancer
4 years ago
Long term AR signaling‐targeted therapy with taxane sometimes associated with visceral metastasis in castration‐resistant prostate cancer
The present study was conducted to present androgen receptor signaling‐targeted therapy and taxane chemotherapy induce visceral metastasis in
castration
‐resistant prostate cancer.
The present study was conducted to present androgen receptor signaling‐targeted therapy and taxane chemotherapy induce visceral metastasis in
castration
‐resistant prostate cancer.
George71
in
Advanced Prostate Cancer
4 years ago
Not a candidate for the CAR-T trial. Should I pursue cabozantinib here in the USA or look abroad for LU-177?
Of course you need to have the PSMA receptor for this to be effective but I hear some really good regression is a number of men who have
castration
resistance and who have failed docetaxel. Any thoughts brothers?
Of course you need to have the PSMA receptor for this to be effective but I hear some really good regression is a number of men who have
castration
resistance and who have failed docetaxel. Any thoughts brothers?
Cleodman
in
Advanced Prostate Cancer
4 years ago
Greater Subcutaneous Fat Improves mCRPC Treatment Response
https://www.cancertherapyadvisor.com/home/cancer-topics/prostate-cancer/adipose-tissue-metastatic-
castration
-resistant-pca-tx-response/ I thought it was the other way around.
https://www.cancertherapyadvisor.com/home/cancer-topics/prostate-cancer/adipose-tissue-metastatic-
castration
-resistant-pca-tx-response/ I thought it was the other way around.
George71
in
Advanced Prostate Cancer
4 years ago
What is Changing in Advanced Prostate Cancer?
Isn't almost all metastatic PCa eventually
castration
resistant????
Isn't almost all metastatic PCa eventually
castration
resistant????
maley2711
in
Advanced Prostate Cancer
4 years ago
Is ADT necessary when you take Zytiga?
"ADT, which causes
castration
, or the removal of androgens such as testosterone from the body, comes with many significant adverse side effects.
"ADT, which causes
castration
, or the removal of androgens such as testosterone from the body, comes with many significant adverse side effects.
pjoshea13
in
Advanced Prostate Cancer
4 years ago
BAT
The bipolar androgen therapy is an under-investigation treatment that consists in periodical oscillation between
castration
levels and supraphysiological levels of testosterone in order to prevent the adaptation of prostate cancer cells to a low-androgen environment.
The bipolar androgen therapy is an under-investigation treatment that consists in periodical oscillation between
castration
levels and supraphysiological levels of testosterone in order to prevent the adaptation of prostate cancer cells to a low-androgen environment.
podsart
in
Advanced Prostate Cancer
4 years ago
$150-200 Research Study for you
US residents only Confirmed mCRPC diagnosis (metastatic
castration
-resistant) Aim for mix of home setting (i.e. rural, urban, suburban) Aim for range of time since diagnosis Mix of patients with different number of lines of treatment received Mix of treatments Aim for mix of ethnicities Ryan Tomlinson
US residents only Confirmed mCRPC diagnosis (metastatic
castration
-resistant) Aim for mix of home setting (i.e. rural, urban, suburban) Aim for range of time since diagnosis Mix of patients with different number of lines of treatment received Mix of treatments Aim for mix of ethnicities Ryan Tomlinson
Darryl
Partner
in
Advanced Prostate Cancer
4 years ago
Tolerability and treatment response to darolutamide in patients with nmCRPC in the phase III ARAMIS trial
Effectiveness related to the PSA decline from baseline. https://oncologypro.esmo.org/meeting-resources/esmo-virtual-congress-2020/tolerability-and-treatment-response-to-darolutamide-daro-in-patients-with-non-metastatic-
castration
-resistant-prostate-cancer-nmcrpc-in-the-pha
Effectiveness related to the PSA decline from baseline. https://oncologypro.esmo.org/meeting-resources/esmo-virtual-congress-2020/tolerability-and-treatment-response-to-darolutamide-daro-in-patients-with-non-metastatic-
castration
-resistant-prostate-cancer-nmcrpc-in-the-pha
tango65
in
Advanced Prostate Cancer
4 years ago
BAT: transformer trial
https://ascopubs.org/doi/abs/10.1200/JCO.2020.38.15_suppl.5517 https://www.urotoday.com/conference-highlights/asco-2020/asco-2020-prostate-cancer/121890-asco-2020-transformer-bipolar-androgen-therapy-vs-enzalutamide-for-
castration
-resistant-metastatic-prostate-cancer.html https://www.urotoday.com/video-lectures
https://ascopubs.org/doi/abs/10.1200/JCO.2020.38.15_suppl.5517 https://www.urotoday.com/conference-highlights/asco-2020/asco-2020-prostate-cancer/121890-asco-2020-transformer-bipolar-androgen-therapy-vs-enzalutamide-for-
castration
-resistant-metastatic-prostate-cancer.html https://www.urotoday.com/video-lectures
kaptank
in
Advanced Prostate Cancer
4 years ago
It's been a full week since my castration...and feeling GREAT.
My surgical orchidectomy was last Monday afternoon. In my attempt to keep everyone interested "posted" on my journey.... I have more energy than I have had in months(since before Radiation in Feb/Mar)....it might be because the weather has finally cooled down to the 70's and low 80's here in Ft. Lauderdale
My surgical orchidectomy was last Monday afternoon. In my attempt to keep everyone interested "posted" on my journey.... I have more energy than I have had in months(since before Radiation in Feb/Mar)....it might be because the weather has finally cooled down to the 70's and low 80's here in Ft. Lauderdale
greatjohn
in
Advanced Prostate Cancer
4 years ago
Title :Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer
With all the interest in my last post I thought some might be interested in this: https://www.cureitt.com/trialdetails?nctid=NCT03123978 Maybe someone out there could explain the difference between niclosamide and Fenbendazole, they are both used for deworming dogs.
With all the interest in my last post I thought some might be interested in this: https://www.cureitt.com/trialdetails?nctid=NCT03123978 Maybe someone out there could explain the difference between niclosamide and Fenbendazole, they are both used for deworming dogs.
Magnus1964
in
Advanced Prostate Cancer
4 years ago
Castrate resistant with Mets
What is the life expectancy with stage 4
castration
resistant and Mets to three areas of the bones? On an average. He just started taking Zytiga!!
What is the life expectancy with stage 4
castration
resistant and Mets to three areas of the bones? On an average. He just started taking Zytiga!!
Fight11
in
Advanced Prostate Cancer
4 years ago
New Car-T therapy announces initial results, how exercise helps in the fight against cancer, FDA approves EZRA AI for faster PC diagnosis
https://www.globenewswire.com/news-release/2020/10/26/2114227/0/en/Mustang-Bio-Announces-Initial-Phase-1-Data-on-MB-105-for-Patients-with-PSCA-positive-
Castration
-Resistant-Prostate-Cancer.html The clinical trial is STILL RECRUITING--out of City of Hope....some info: https://clinicaltrials.gov/ct2/show
https://www.globenewswire.com/news-release/2020/10/26/2114227/0/en/Mustang-Bio-Announces-Initial-Phase-1-Data-on-MB-105-for-Patients-with-PSCA-positive-
Castration
-Resistant-Prostate-Cancer.html The clinical trial is STILL RECRUITING--out of City of Hope....some info: https://clinicaltrials.gov/ct2/show
NPfisherman
in
Fight Prostate Cancer
4 years ago
Princess Grace Hospital in Monaco
I chose RT plus chemical
castration
by 2 injections over six months of Enantone , Takeda Japanese Lab . My RT consisted of 38 sessions of 2Gy on Prostate , prealably contoured by three gold grains and my SV received 54 Gy . I asked why the SV also ?
I chose RT plus chemical
castration
by 2 injections over six months of Enantone , Takeda Japanese Lab . My RT consisted of 38 sessions of 2Gy on Prostate , prealably contoured by three gold grains and my SV received 54 Gy . I asked why the SV also ?
thierry
in
Prostate Cancer Network
4 years ago
Recurrence after Therapy for Oligometastatic Castration Sensitive PCa
"Metastasis directed therapy (MDT) is increasingly used in
castration
-sensitive oligometastatic prostate cancer (OPCa) because it prolongs progression free survival (PFS) and androgen deprivation free survival."
"Metastasis directed therapy (MDT) is increasingly used in
castration
-sensitive oligometastatic prostate cancer (OPCa) because it prolongs progression free survival (PFS) and androgen deprivation free survival."
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Sipuleucel-T boosts survival versus abiraterone or enzalutamide alone in real-world mCRPC analysis
Real-world data showed that use of the immunotherapy sipuleucel-T (Provenge) during any line of treatment in men with metastatic
castration
-resistant prostate cancer (mCRPC) improved overall survival (OS) versus treatment regimens that included abiraterone acetate (Zytiga) or enzalutamide (Xtandi), but
Real-world data showed that use of the immunotherapy sipuleucel-T (Provenge) during any line of treatment in men with metastatic
castration
-resistant prostate cancer (mCRPC) improved overall survival (OS) versus treatment regimens that included abiraterone acetate (Zytiga) or enzalutamide (Xtandi), but
George71
in
Advanced Prostate Cancer
4 years ago
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