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ARPIs May Improve Survival in Some With Prostate Cancer
We are talking about sequential therapy in this case, triplet is a different story (and it's used in
castration
sensitive setting). https://www.curetoday.com/view/arpis-may-improve-survival-in-some-with-prostate-cancer
We are talking about sequential therapy in this case, triplet is a different story (and it's used in
castration
sensitive setting). https://www.curetoday.com/view/arpis-may-improve-survival-in-some-with-prostate-cancer
Maxone73
in
Advanced Prostate Cancer
1 month ago
could be of interest for those on BAT
Extreme responses to immune checkpoint blockade following bipolar androgen therapy and enzalutamide in patients with metastatic
castration
resistant prostate cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585736/
Extreme responses to immune checkpoint blockade following bipolar androgen therapy and enzalutamide in patients with metastatic
castration
resistant prostate cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585736/
Maxone73
in
Advanced Prostate Cancer
4 months ago
New way to delay resistance in prostate cancer
So it's not a cure or a new therapy per se, but can be useful to delay
castration
resistance (or maybe even invert it, but the article does not talk about it).
So it's not a cure or a new therapy per se, but can be useful to delay
castration
resistance (or maybe even invert it, but the article does not talk about it).
Maxone73
in
Advanced Prostate Cancer
2 months ago
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There will be updates about CC-94676 at ESMO 2024 in september in Barcelona
CC-94676 or BMS-986365 is a highly selective AR degrade for
castration
resistant prostate cancer, the first good results were reported in January this year, but in September we will get more news at ESMO 2024 https://cslide.ctimeetingtech.com/esmo2024/attendee/confcal/presentation/list?
CC-94676 or BMS-986365 is a highly selective AR degrade for
castration
resistant prostate cancer, the first good results were reported in January this year, but in September we will get more news at ESMO 2024 https://cslide.ctimeetingtech.com/esmo2024/attendee/confcal/presentation/list?
Maxone73
in
Advanced Prostate Cancer
2 months ago
Low testosterone, rising PSA
Castration
resistance? I have 2 options to think about: 1) to wait untill PSA reaches around 0.7 or more and than another PSMAPETC as I did before. 2)ADT+ Zytiga immediately and see what happens. Your opinions? Thank you all.
Castration
resistance? I have 2 options to think about: 1) to wait untill PSA reaches around 0.7 or more and than another PSMAPETC as I did before. 2)ADT+ Zytiga immediately and see what happens. Your opinions? Thank you all.
Alinur
in
Advanced Prostate Cancer
5 days ago
Niclosamide-based metabolic anticancer drug's first clinical trial will target CRPC
Yes, they will start from
castration
resistant prostate cancer patients https://www.biospace.com/article/releases/adm-korea-announces-niclosamide-based-metabolic-anticancer-drug-s-first-clinical-trial-target-as-prostate-cancer-patients-resistant-to-hormone-therapy-/ EDIT: for some reason that link
Yes, they will start from
castration
resistant prostate cancer patients https://www.biospace.com/article/releases/adm-korea-announces-niclosamide-based-metabolic-anticancer-drug-s-first-clinical-trial-target-as-prostate-cancer-patients-resistant-to-hormone-therapy-/ EDIT: for some reason that link
Maxone73
in
Advanced Prostate Cancer
3 months ago
ARASENS: more positive data about castration resistance
New article, but I think that I have already written about this...basically, it seems to delay
castration
resistance in prostate cancer.
New article, but I think that I have already written about this...basically, it seems to delay
castration
resistance in prostate cancer.
Maxone73
in
Advanced Prostate Cancer
3 months ago
PALB2 Stage 4 A prostate cancer treatment plan.
Is it because the FDA has approved the latter only if
castration
resistant?
Is it because the FDA has approved the latter only if
castration
resistant?
SherryKahn
in
Advanced Prostate Cancer
4 months ago
Vorinostat trial
I have been invited to participate in a clinical trial (phase 2) at the Univ of WA, Fred Hutch cancer center: Vorinostat to Augment Response to 177 Lutetium-PSMA-617 in the treatment of patients with PSMA- low metastatic
castration
resistant prostate cancer: VALOR TRIAL.
I have been invited to participate in a clinical trial (phase 2) at the Univ of WA, Fred Hutch cancer center: Vorinostat to Augment Response to 177 Lutetium-PSMA-617 in the treatment of patients with PSMA- low metastatic
castration
resistant prostate cancer: VALOR TRIAL.
dulcimerdude
in
Advanced Prostate Cancer
1 month ago
Theoretical and in-vitro study of Sparganii and Curcumin together for castration resistant prostate cancer
Exploring the mechanism of action of Sparganii Rhizoma-Curcumae Rhizoma for in treating
castration
-resistant prostate cancer: a network-based pharmacology and experimental validation study.
Exploring the mechanism of action of Sparganii Rhizoma-Curcumae Rhizoma for in treating
castration
-resistant prostate cancer: a network-based pharmacology and experimental validation study.
Graham49
in
Advanced Prostate Cancer
1 month ago
Extremely tired of chemical castration
I'm interested in chatting with those who have had an orchiectomy, guess thats how you spell it. I'm tired of all the side affects of cancer drugs and all the problems they cause to my body so I'm concidering having an orchiectomy. Yes I know all about what happens when you get this but as far as I'm
I'm interested in chatting with those who have had an orchiectomy, guess thats how you spell it. I'm tired of all the side affects of cancer drugs and all the problems they cause to my body so I'm concidering having an orchiectomy. Yes I know all about what happens when you get this but as far as I'm
woppaginny
in
Advanced Prostate Cancer
5 months ago
advice please!
I will also have a
castration
surgery to stop the testosterone from fueling the cancer. I am hoping to find a more natural less invasive way of slowing down the cancer and even it going back into remission if possible. Please send recommendations.
I will also have a
castration
surgery to stop the testosterone from fueling the cancer. I am hoping to find a more natural less invasive way of slowing down the cancer and even it going back into remission if possible. Please send recommendations.
BonnieKlyde
in
Advanced Prostate Cancer
3 months ago
More on ARX517 in mCRPC
More info about this option for
castration
resistant prostate cancer https://www.onclive.com/view/dr-shen-on-the-utility-of-arx517-in-mcrpc
More info about this option for
castration
resistant prostate cancer https://www.onclive.com/view/dr-shen-on-the-utility-of-arx517-in-mcrpc
Maxone73
in
Advanced Prostate Cancer
7 months ago
Positive case studies
Jo 9 yearWe present a case of a patient with
castration
-resistant prostate cancer with proven bone lesions 2 years after the onset of the disease and the current survival of over 9 years.
Jo 9 yearWe present a case of a patient with
castration
-resistant prostate cancer with proven bone lesions 2 years after the onset of the disease and the current survival of over 9 years.
TomsD1
in
Advanced Prostate Cancer
2 months ago
Radium 223 + Enzalutamide increase rPFS in castration resistante prostate cancer
As Tall Allen posted, here is the link to the numbers: https://www.onclive.com/view/addition-of-radium-223-to-enzalutamide-significantly-improves-rpfs-and-os-in-mcrpc
As Tall Allen posted, here is the link to the numbers: https://www.onclive.com/view/addition-of-radium-223-to-enzalutamide-significantly-improves-rpfs-and-os-in-mcrpc
Maxone73
in
Advanced Prostate Cancer
17 days ago
ESMO 2024: Phase 3 evaluation of transdermal estradiol vs LHRH agonists for androgen suppression
Both groups achieved similar rates of sustained
castration
, defined by low testosterone levels over one year.
Both groups achieved similar rates of sustained
castration
, defined by low testosterone levels over one year.
Maxone73
in
Advanced Prostate Cancer
15 days ago
"Castration resistant"
Can I assume I am
Castration
resistant?
Can I assume I am
Castration
resistant?
GrantB47
in
Advanced Prostate Cancer
8 months ago
ESMO 2024 - UpFrontPSMA: randomized study of sequential 177Lu-PSMA-617 and Docetaxel vs Docetaxel in metastatic prostate cancer
Delayed Development of
Castration
Resistance: HR of 0.60 (p=0.033).
Delayed Development of
Castration
Resistance: HR of 0.60 (p=0.033).
Maxone73
in
Advanced Prostate Cancer
15 days ago
Antiandrogen Withdrawal Syndrome After Stopping Enzalutamide in Metastatic Castration-Resistant Prostate Cancer: Two Case Reports & Review
/ Abstract Metastatic prostate cancer treatment is based on androgen deprivation, with pharmacological or surgical
castration
. This treatment may be complemented with the addition of antiandrogenic drugs.
/ Abstract Metastatic prostate cancer treatment is based on androgen deprivation, with pharmacological or surgical
castration
. This treatment may be complemented with the addition of antiandrogenic drugs.
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
177Lu-PNT2002 improves OS compared to ARPIs in metastatic castration resistant prostate cancer
as presented by dr Sartor at ESMO 2024 https://www.urotoday.com/conference-highlights/esmo-2024/esmo-2024-prostate-cancer/154850-esmo-2024-efficacy-of-177lu-pnt2002-in-psma-positive-mcrpc-following-progression-on-an-androgen-receptor-pathway-inhibitor-splash.html
as presented by dr Sartor at ESMO 2024 https://www.urotoday.com/conference-highlights/esmo-2024/esmo-2024-prostate-cancer/154850-esmo-2024-efficacy-of-177lu-pnt2002-in-psma-positive-mcrpc-following-progression-on-an-androgen-receptor-pathway-inhibitor-splash.html
Maxone73
in
Advanced Prostate Cancer
15 days ago
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