Search
Search
About
Log in
Join
Experiences with
Castration
Posts
Communities
1,126 public posts
Filter results
ASCO Issues New Guidelines for Optimizing Anticancer Therapy in Metastatic non-CRPC.
. - The appropriate regimen of abiraterone is 1,000 mg with either prednisolone or prednisone 5 mg once daily until treatment(s) for metastatic
castration
-resistant disease are initiated. - The panel noted that ADT plus docetaxel vs ADT plus abiraterone have not been compared, and it is unknown if some
. - The appropriate regimen of abiraterone is 1,000 mg with either prednisolone or prednisone 5 mg once daily until treatment(s) for metastatic
castration
-resistant disease are initiated. - The panel noted that ADT plus docetaxel vs ADT plus abiraterone have not been compared, and it is unknown if some
pjoshea13
in
Advanced Prostate Cancer
6 years ago
A "Novel" CRPC Mechanism.
Persistence of intratumoral androgens has been found in
castration
-resistant prostate cancer and attributed to increased in situ synthesis. Recently, Sharifi and colleagues reported an additional mechanism that can enhance local androgenic exposure: downregulation of an androgen-inactivating enzyme.
Persistence of intratumoral androgens has been found in
castration
-resistant prostate cancer and attributed to increased in situ synthesis. Recently, Sharifi and colleagues reported an additional mechanism that can enhance local androgenic exposure: downregulation of an androgen-inactivating enzyme.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
ASCO Genitourinary Cancers Symposium (Statin use & outcomes.)
{prednisone (P), abiraterone (AA)} -Patrick 230 Poster Session (Board #L6), Thu, 11:30 AM-1:00 PM and 5:15 PM-6:15 PM Impact of statins on outcomes in patients (pts) with metastatic
castration
resistant prostate cancer (mCRPC): Post-hoc analysis of data from COU-AA-301 and COU-AA-302 trials.
{prednisone (P), abiraterone (AA)} -Patrick 230 Poster Session (Board #L6), Thu, 11:30 AM-1:00 PM and 5:15 PM-6:15 PM Impact of statins on outcomes in patients (pts) with metastatic
castration
resistant prostate cancer (mCRPC): Post-hoc analysis of data from COU-AA-301 and COU-AA-302 trials.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
ASCO Genitourinary Cancers Symposium (Statins again)
-Patrick 277 Poster Session (Board #N9), Thu, 11:30 AM-1:00 PM and 5:15 PM-6:15 PM Statin use and outcomes of patients (pts) with metastatic
castration
resistant prostate cancer (mCRPC) being treated with abiraterone (Abi). Jacob A Gordon, Bernhard J. Eigl, Jennifer A.
-Patrick 277 Poster Session (Board #N9), Thu, 11:30 AM-1:00 PM and 5:15 PM-6:15 PM Statin use and outcomes of patients (pts) with metastatic
castration
resistant prostate cancer (mCRPC) being treated with abiraterone (Abi). Jacob A Gordon, Bernhard J. Eigl, Jennifer A.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Ralaniten [EPI-506]
Unfortunately, the clinical trial "Safety and Anti-Tumor Study of Oral EPI-506 for Patients With Metastatic
Castration
-Resistant Prostate Cancer" has been terminated: "At end of Phase 1 excessive high pill burden (18 capsules/day)" [3] 18 caps? Why, that's nothing to Nalakrats.
Unfortunately, the clinical trial "Safety and Anti-Tumor Study of Oral EPI-506 for Patients With Metastatic
Castration
-Resistant Prostate Cancer" has been terminated: "At end of Phase 1 excessive high pill burden (18 capsules/day)" [3] 18 caps? Why, that's nothing to Nalakrats.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Practical Guidance on the Role of Corticosteroids in the Treatment of Metastatic Castration-resistant Prostate Cancer
Good general information for reference regarding the use of corticosteroids in MCRPC https://www.sciencedirect.com/science/article/pii/S0090429516001461
Good general information for reference regarding the use of corticosteroids in MCRPC https://www.sciencedirect.com/science/article/pii/S0090429516001461
Hidden
in
Advanced Prostate Cancer
6 years ago
Quality of Life in Second-Line Treatment of Metastatic Castration-Resistant Prostate
Found a very interesting article on a trial done in Switzerland regarding quality of life in MCRPC patients who took different second-line treatments after ADT and Docetaxel chemotherapy. So many of the guidelines for second-line treatments I've found refer to "Chemotherapy-Naive" patients. Here, they
Found a very interesting article on a trial done in Switzerland regarding quality of life in MCRPC patients who took different second-line treatments after ADT and Docetaxel chemotherapy. So many of the guidelines for second-line treatments I've found refer to "Chemotherapy-Naive" patients. Here, they
Hidden
in
Advanced Prostate Cancer
6 years ago
Neutrophil-to-Lymphocyte ratio [NLR] & Abiraterone.
Baseline neutrophil-to-lymphocyte ratio predicts the prognosis of
castration
-resistant prostate cancer treated with abiraterone acetate. Yasui M1, Hasegawa Y2, Kawahara T1, Kumano Y1, Miyoshi Y1, Matsubara N2, Uemura H1.
Baseline neutrophil-to-lymphocyte ratio predicts the prognosis of
castration
-resistant prostate cancer treated with abiraterone acetate. Yasui M1, Hasegawa Y2, Kawahara T1, Kumano Y1, Miyoshi Y1, Matsubara N2, Uemura H1.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
I'm Struggling
Over the past 6 months (since chemo finished) my PSA has risen from 0.69 to 3.6 and my oncologist has confirmed
castration
resistance. I can handle this also. I have recently added Xtandi to the mix. The scary development has been progression in bony mets.
Over the past 6 months (since chemo finished) my PSA has risen from 0.69 to 3.6 and my oncologist has confirmed
castration
resistance. I can handle this also. I have recently added Xtandi to the mix. The scary development has been progression in bony mets.
paulofaus
in
Advanced Prostate Cancer
6 years ago
Vitamin K2.
I reviewed the literature a year ago in: "Foods/Supplements-Vitamins: Vitamin K" In the new study: "Vitamin K2, a menaquinone ... targets
castration
-resistant prostate cancer cell-line by activating apoptosis signaling."
I reviewed the literature a year ago in: "Foods/Supplements-Vitamins: Vitamin K" In the new study: "Vitamin K2, a menaquinone ... targets
castration
-resistant prostate cancer cell-line by activating apoptosis signaling."
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Interesting result for BRCA patients from ASCO2018
"Effect of germline DNA repair gene mutations on outcomes in men with metastatic
castration
-resistant prostate cancer receiving first-line abiraterone and enzalutamide."
"Effect of germline DNA repair gene mutations on outcomes in men with metastatic
castration
-resistant prostate cancer receiving first-line abiraterone and enzalutamide."
snoraste
in
Advanced Prostate Cancer
6 years ago
ORCHIECTOMY OR ADT??
I have no hang up about
castration
since they have already done that with ADT. I do wonder if after surgery there is any improvement in the ADT symptoms. Is osteopenia a bigger concern long term if surgery is the method of
castration
? l
I have no hang up about
castration
since they have already done that with ADT. I do wonder if after surgery there is any improvement in the ADT symptoms. Is osteopenia a bigger concern long term if surgery is the method of
castration
? l
steinmother
in
Prostate Cancer Network
6 years ago
Quality of Life Follow up LATITUDE trial (Zytiga+Prednisone+ADT)
of the LATITUDE trial was designed to evaluate patient-reported outcomes with ADT plus abiraterone/prednisone or placebo in men with
castration
-naïve prostate cancer.
of the LATITUDE trial was designed to evaluate patient-reported outcomes with ADT plus abiraterone/prednisone or placebo in men with
castration
-naïve prostate cancer.
snoraste
in
Advanced Prostate Cancer
6 years ago
Long-term remission of prostate cancer with extensive bone metastases upon immuno- and virotherapy: A case report
In a phase III trial, following vaccination with activated autologous DC, a prolonged overall survival time was demonstrated in patients suffering from
castration
-resistant prostate cancer (4).
In a phase III trial, following vaccination with activated autologous DC, a prolonged overall survival time was demonstrated in patients suffering from
castration
-resistant prostate cancer (4).
JLS1
in
Advanced Prostate Cancer
6 years ago
Recent article about Lutetium 177 treatment in advanced mCRPC by doctors at the Technical University of Munich
Munich, Munich, Germany; Technical University of Munich, Munich, Germany Abstract Disclosures Background: To report our clinical experience with 177Lutetium-labeled prostate-specific membrane antigen-ligand (177Lu-PSMA-I&T) for systemic radioligand therapy in 100 consecutive patients with metastatic
castration
-resistant
Munich, Munich, Germany; Technical University of Munich, Munich, Germany Abstract Disclosures Background: To report our clinical experience with 177Lutetium-labeled prostate-specific membrane antigen-ligand (177Lu-PSMA-I&T) for systemic radioligand therapy in 100 consecutive patients with metastatic
castration
-resistant
Hidden
in
Advanced Prostate Cancer
6 years ago
CRPC & Avodart [Dutasteride].
Abstract It has previously been demonstrated that the intratumoral generation of the potent androgen dihydrotestosterone (DHT), contributes critically to the progression of prostate cancer and its
castration
-resistant form,
castration
-resistant prostate cancer (CRPC).
Abstract It has previously been demonstrated that the intratumoral generation of the potent androgen dihydrotestosterone (DHT), contributes critically to the progression of prostate cancer and its
castration
-resistant form,
castration
-resistant prostate cancer (CRPC).
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Jevtana [Cabazitaxel] & Androgen Status.
Thereby, maintaining its role even in
castration
resistant prostate cancer (CRPC).
Thereby, maintaining its role even in
castration
resistant prostate cancer (CRPC).
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Non-PCa Prescription Drugs: Thalidomide / Lenalidomide (Revlimid)
An anecdotal German case (2012) [6]: "Long-term disease stabilization in a patient with
castration
-resistant metastatic prostate cancer by the addition of lenalidomide to low-dose dexamethasone and celecoxib."
An anecdotal German case (2012) [6]: "Long-term disease stabilization in a patient with
castration
-resistant metastatic prostate cancer by the addition of lenalidomide to low-dose dexamethasone and celecoxib."
pjoshea13
in
Advanced Prostate Cancer
6 years ago
ASCO Genitourinary Cancers Symposium (Xofigo - Radium-223 retreatment)
population, led to minimal hematologic toxicity, and provided continued disease control in bone at 2-year follow-up." [1] -Patrick [1] 178 Poster Session (Board #H18), Thu, 11:30 AM-1:00 PM and 5:15 PM-6:15 PM Radium-223 retreatment in an international, open-label, phase 1/2 study in patients with
castration
-resistant
population, led to minimal hematologic toxicity, and provided continued disease control in bone at 2-year follow-up." [1] -Patrick [1] 178 Poster Session (Board #H18), Thu, 11:30 AM-1:00 PM and 5:15 PM-6:15 PM Radium-223 retreatment in an international, open-label, phase 1/2 study in patients with
castration
-resistant
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Bipolar Androgen Therapy in Men With Metastatic Castration-Resistant Prostate Cancer After Progression on Enzalutamide
http://www.practiceupdate.com/content/bipolar-androgen-therapy-in-men-with-metastatic-
castration
-resistant-prostate-cancer-after-progression-on-enzalutamide/62093/61/11/1
http://www.practiceupdate.com/content/bipolar-androgen-therapy-in-men-with-metastatic-
castration
-resistant-prostate-cancer-after-progression-on-enzalutamide/62093/61/11/1
snoraste
in
Advanced Prostate Cancer
6 years ago
1
...
49
50
51
...
57
Next page
10
20
30
40
50
Filter results
Clear filters
Posted in
All communities
Advanced Prostate Cancer
1003 results
Fight Prostate Cancer
67 results
Prostate Cancer Network
25 results
View top 10 communities
Sort by
Most Relevant
Newest