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What is role of hormonal therapy drug when taken with targeted therapy, eg Piqray or Ibrance?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
I’ve been curious about this and wondering if anyone can explain. I want to better understand the role of the hormone therapy eg Faslodex when taken with targeted therapy such as Ibrance. Does it just reduce the amount of estrogen available to the cell and “lightens the load” on the targeted therapy?
HelenWi
in
SHARE Metastatic Breast Cancer
7 months ago
Thyroidectomy in Buckinghamshire or Oxfordshire?
Is there anyone on here who has had a partial or full thyroidectomy in Buckinghamshire or Oxfordshire who would be happy to share their experience, good or bad, and provide any tips/advice? Having had nodules for a number of years, one of mine increased in size in Jan 22. It has recently been categorised
Is there anyone on here who has had a partial or full thyroidectomy in Buckinghamshire or Oxfordshire who would be happy to share their experience, good or bad, and provide any tips/advice? Having had nodules for a number of years, one of mine increased in size in Jan 22. It has recently been categorised
Ali-Bucks
in
Thyroid UK
8 months ago
PET Scan follow up
Results from test are in and unfortunatley don't see my MD until Tuesday - looks like they are suggesting recurrence :(. Just when I hit the magic 5 year mark too..... Study Result Impression Increased thickening and nodularity along the anteromedial aspect of the suture line since 2019 with heterogeneous
Results from test are in and unfortunatley don't see my MD until Tuesday - looks like they are suggesting recurrence :(. Just when I hit the magic 5 year mark too..... Study Result Impression Increased thickening and nodularity along the anteromedial aspect of the suture line since 2019 with heterogeneous
kri312
in
Lung Cancer Support
1 year ago
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Tricking the cancer
Is pca truly a cancer or just mother nature selecting me to make way for something else??? Seems like the treatments for pca are just trying trick mother nature. The trick seems to be turn us into female versions???? Chop balls of Remove testosterone Grow moobs Menopause
Is pca truly a cancer or just mother nature selecting me to make way for something else??? Seems like the treatments for pca are just trying trick mother nature. The trick seems to be turn us into female versions???? Chop balls of Remove testosterone Grow moobs Menopause
Mrtroxely
in
Advanced Prostate Cancer
1 year ago
Update and advice needed!!
Just a quick update and would also appreciate any advice.My lovely mum has met with the Consultant who reviewed her images. Ca 125 was 239. MRI liver normal which was great news. However, they are now requesting tumour markers for the pancreas and liver along with a biopsy of the peritoneal mass. The
Just a quick update and would also appreciate any advice.My lovely mum has met with the Consultant who reviewed her images. Ca 125 was 239. MRI liver normal which was great news. However, they are now requesting tumour markers for the pancreas and liver along with a biopsy of the peritoneal mass. The
ORGM
in
My Ovacome
1 year ago
thoughts 🙏
hi everyone, my dad has had MBC since June of 2022. He has been on Ibrance, letrozole, lupron, and xjeva. His Mets were to bone and then he was NED for a year from June 2022 to June 2023. In July he took a PET scan and it showed a slight uptake of activity to his chest wall. Plan was to keep him on
hi everyone, my dad has had MBC since June of 2022. He has been on Ibrance, letrozole, lupron, and xjeva. His Mets were to bone and then he was NED for a year from June 2022 to June 2023. In July he took a PET scan and it showed a slight uptake of activity to his chest wall. Plan was to keep him on
Jenniferp2122
in
SHARE Metastatic Breast Cancer
7 months ago
results - post op lobectomy
hi 👋🏽 What does mean please? appear polytypic. AE1/AE3 is negative. The lymph node shows prominent sinus histiocytosis. Features are consistent with a reactive hilar lymph node. In summary, there is a prominent non-specific bronchial inflammatory infiltrate with no obvious evidence of lymphoid
hi 👋🏽 What does mean please? appear polytypic. AE1/AE3 is negative. The lymph node shows prominent sinus histiocytosis. Features are consistent with a reactive hilar lymph node. In summary, there is a prominent non-specific bronchial inflammatory infiltrate with no obvious evidence of lymphoid
AnnaDora
in
The Roy Castle Lung Cancer Foundation
1 year ago
Ramp 201 Trial
Good evening everyone, hope you all have had a good day, or a better one. Just wondering if any of you may be on the Ramp 201 trial, or Frame. I feel I should start researching what could be worth considering as an option for me, since it seems progression to be happening based on my last three CA
Good evening everyone, hope you all have had a good day, or a better one. Just wondering if any of you may be on the Ramp 201 trial, or Frame. I feel I should start researching what could be worth considering as an option for me, since it seems progression to be happening based on my last three CA
jsc50
in
My Ovacome
1 year ago
"PYRUVATE HD +" Has anyone had this or know what this is- looked on interweb- goggledygook! what is it- in simple terms please?
Hi guys- hope you are all doing OK. I've had my PBC diagnosis confirmed- relief finally! Changed GP, hopefully, new surgery will listen and be helpful... got my medical records from old surgery, found all they seem to do is blood tests- but no action!
Hi guys- hope you are all doing OK. I've had my PBC diagnosis confirmed- relief finally! Changed GP, hopefully, new surgery will listen and be helpful... got my medical records from old surgery, found all they seem to do is blood tests- but no action!
Deeplydepp
in
PBC Foundation
1 year ago
Carboplatin & Etoposide
Hi everyone. My dad will be starting Carboplatin and Etoposide next Monday. I was hoping to get some tips for helping make my dad comfortable. I have read random tips such as starting Claritin before and buying ice mitts/hat, etc. but wanted to ask those who have been through chemo, what are some helpful
Hi everyone. My dad will be starting Carboplatin and Etoposide next Monday. I was hoping to get some tips for helping make my dad comfortable. I have read random tips such as starting Claritin before and buying ice mitts/hat, etc. but wanted to ask those who have been through chemo, what are some helpful
antisocialsocialwrkr
in
Advanced Prostate Cancer
1 year ago
Chemo may be helping
Hi Fellow Fighters, Prior to my third round of Taxotere last Friday, I had blood work done. After 2 rounds, my PSA dropped 4.7 points. TBH, I feel like crap today, but the results are promising. My blood work also showed low cortisol levels, how concerned should I be about that? Thanks.
Hi Fellow Fighters, Prior to my third round of Taxotere last Friday, I had blood work done. After 2 rounds, my PSA dropped 4.7 points. TBH, I feel like crap today, but the results are promising. My blood work also showed low cortisol levels, how concerned should I be about that? Thanks.
MJCA
in
Advanced Prostate Cancer
1 year ago
Changing mole
Hi, first time posting and have some questions that would appreciate some help with. Have a mole on shoulder that has recently increased in size (elevated) and now approx 8mm, dark pink/brown with red centre and dip in middle with some crusting/scab. Had online private GP appt (as have private medical
Hi, first time posting and have some questions that would appreciate some help with. Have a mole on shoulder that has recently increased in size (elevated) and now approx 8mm, dark pink/brown with red centre and dip in middle with some crusting/scab. Had online private GP appt (as have private medical
ShonaGreen
in
Skin Cancer UK
1 year ago
why did I not go sooner
hi, I have a large (3cm) acoustic neuroma diagnosed this week. I will find out the recommendation in 2 weeks. I always put my loss of hearing and tinnitus down to stress. But then I started getting a fullness feeling in my ear and had a hearing test and MRI. It worries me about surgery and the not
hi, I have a large (3cm) acoustic neuroma diagnosed this week. I will find out the recommendation in 2 weeks. I always put my loss of hearing and tinnitus down to stress. But then I started getting a fullness feeling in my ear and had a hearing test and MRI. It worries me about surgery and the not
Jayme48
in
Acoustic Neuroma Support
1 year ago
Joining here on Mother’s Day
I’m Lakshmi from Bangalore, india. I work as a consultant with NGOs. Im a member of the Diabetes community too. I’m 72 and the mother of a lovely young woman, a breast cancer survivor who got the big C at age 36. Now 7 years on, she’s experiencing painful side effects of the Tamoxifen hormone treatment
I’m Lakshmi from Bangalore, india. I work as a consultant with NGOs. Im a member of the Diabetes community too. I’m 72 and the mother of a lovely young woman, a breast cancer survivor who got the big C at age 36. Now 7 years on, she’s experiencing painful side effects of the Tamoxifen hormone treatment
suryakaizen
in
SHARE Breast Cancer Support
1 year ago
Radiation
I had the standard IMRT for my pca back in 2013. I was told it was a lifetime dose. Is that true with the newer forms of radiation treatment? I am faced with starting a six dose regimen of taxotere now since ADT does not seem to be working according to PSMA scans. My psa remains at 1.8 even though the
I had the standard IMRT for my pca back in 2013. I was told it was a lifetime dose. Is that true with the newer forms of radiation treatment? I am faced with starting a six dose regimen of taxotere now since ADT does not seem to be working according to PSMA scans. My psa remains at 1.8 even though the
sillyoyster
in
Advanced Prostate Cancer
8 months ago
Capecitabine / Xeloda
Stage 4 Breast Cancer I just started have had three rounds I feel so much better I was in horrible pain with this one. My second time around in two years . I hope they keep experimenting and have some positive news for triple negative. I had some fatigue but nothing I couldn’t handle sleep has returned
Stage 4 Breast Cancer I just started have had three rounds I feel so much better I was in horrible pain with this one. My second time around in two years . I hope they keep experimenting and have some positive news for triple negative. I had some fatigue but nothing I couldn’t handle sleep has returned
Lightwinds
in
SHARE Metastatic Breast Cancer
8 months ago
When do I go from here?
I have tried almost all available options and the numbers continue to get worse. Pending treatment options - immunotherapy (low success rate) or JEVTANA (could buy me a few more months). The last 12 months of constant nausea, which still continues even after I have stopped treatment, has left me very
I have tried almost all available options and the numbers continue to get worse. Pending treatment options - immunotherapy (low success rate) or JEVTANA (could buy me a few more months). The last 12 months of constant nausea, which still continues even after I have stopped treatment, has left me very
barrybayarea
in
Advanced Prostate Cancer
1 year ago
Recurring Pneumonia from Breast Cancer radiation treatment
I was diagnosed with stage 0 breast cancer and went through two lumpectomies in April 2022, and 21 radiation treatments in May 2022, ending early June 2022. By the end of July 2022, I knew something was not right with my left lung with constant coughing, shortness of breath. In fall of 2022 I was diagnosed
I was diagnosed with stage 0 breast cancer and went through two lumpectomies in April 2022, and 21 radiation treatments in May 2022, ending early June 2022. By the end of July 2022, I knew something was not right with my left lung with constant coughing, shortness of breath. In fall of 2022 I was diagnosed
TiaDave
in
Lung Conditions Community Forum
1 year ago
scans
Does anyone know if an mri is carried out after a metastatic adenocarcinoma diagnosis to check the spread of the disease?
Does anyone know if an mri is carried out after a metastatic adenocarcinoma diagnosis to check the spread of the disease?
Sharkypuss
in
The Roy Castle Lung Cancer Foundation
1 year ago
Thyroid cancer
I have a close friend who’s just been diagnosed with thyroid cancer so is waiting for surgery. She has been told this is not the worst cancer to get and it will not kill her. So she is trying to be upbeat about it. Can you live normally without a thyroid please? I’d really like to give her some optimistic
I have a close friend who’s just been diagnosed with thyroid cancer so is waiting for surgery. She has been told this is not the worst cancer to get and it will not kill her. So she is trying to be upbeat about it. Can you live normally without a thyroid please? I’d really like to give her some optimistic
sidneymark70
in
Thyroid UK
8 months ago
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