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1/2 way through Xofigo with Apaludamide increasingly ineffective. PSA is declining. MO tells me Xofigo not the cause.
Hello all. 18 months since diagnosed stage 4 metastatic PC. Mets almost everywhere. PSA was 512 at diagnosis. Apaludamide/Trelstar combo lowered PSA to 0.60. Began to climb again April this year and Xofigo was suggested. I've now completed 3 of 6 treatments. Told Xofigo isn't to reduce PSA by my MO
Hello all. 18 months since diagnosed stage 4 metastatic PC. Mets almost everywhere. PSA was 512 at diagnosis. Apaludamide/Trelstar combo lowered PSA to 0.60. Began to climb again April this year and Xofigo was suggested. I've now completed 3 of 6 treatments. Told Xofigo isn't to reduce PSA by my MO
VisorF9
in
Advanced Prostate Cancer
1 month ago
What’s Next?
My bio illustrates my long 19 year journey with this disease. I turned out to be a great candidate for Pluvicto. All was going well. After cycle 3, a PSMA-PET showed all but one metastases were receding or dead. My PSA before cycle 4 was 17.7. My PSA before cycle 5 was 33.15. Due to the fast increase
My bio illustrates my long 19 year journey with this disease. I turned out to be a great candidate for Pluvicto. All was going well. After cycle 3, a PSMA-PET showed all but one metastases were receding or dead. My PSA before cycle 4 was 17.7. My PSA before cycle 5 was 33.15. Due to the fast increase
MJCA
in
Advanced Prostate Cancer
1 month ago
Xtandi / Lupron constipation
I am about 5 months into Xtandi and Lupron, and having increasingly difficult constipation. It started after the third month but is becoming more prevalent, now using laxatives. (Otc) Anyone have similar side effects? Any prescription meds helpful?
I am about 5 months into Xtandi and Lupron, and having increasingly difficult constipation. It started after the third month but is becoming more prevalent, now using laxatives. (Otc) Anyone have similar side effects? Any prescription meds helpful?
CousinGrandpa
in
Advanced Prostate Cancer
1 month ago
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3rd & 4th pBAT cycle results with daro question
Started 3rd pBAT cycle on 6-4-24 with a PSA of 0.58 measured 1 day earlier, 32 days after last of 6 T injections. Started 4th cycle on 7-26-24 with a PSA of 0.59 measured 2 days earlier, 34 days after last of 9 T injections. Tomorrow I will start my first loT phase with darolutamide (see below question
Started 3rd pBAT cycle on 6-4-24 with a PSA of 0.58 measured 1 day earlier, 32 days after last of 6 T injections. Started 4th cycle on 7-26-24 with a PSA of 0.59 measured 2 days earlier, 34 days after last of 9 T injections. Tomorrow I will start my first loT phase with darolutamide (see below question
Ichthus316
in
Fight Prostate Cancer
1 month ago
prostate cancer
I'm 85 years old, live in Langley, British Columbia have had Metastatic Prostate cancer for about three years, My urologist has had me on Zoladex injections every three months for that time, have had two scans since than,, which does not show any cancer, but after getting the results myself , found
I'm 85 years old, live in Langley, British Columbia have had Metastatic Prostate cancer for about three years, My urologist has had me on Zoladex injections every three months for that time, have had two scans since than,, which does not show any cancer, but after getting the results myself , found
Nikobear
in
Advanced Prostate Cancer
1 month ago
My first PSA after HT reporting confusion
I’ve just finish 19 months of Zoladex and RT to prostate only (localised G9 / PSMA/CT clear no evidence of SV involvement with PSA 6) My usual lab have been reporting my PSA as <0.01 ug/L since RT 18 months ago. My first 3 month testosterone is 0.8 nmol/L (23 ng/dL) and my PSA <0.03 ! Why is it
I’ve just finish 19 months of Zoladex and RT to prostate only (localised G9 / PSMA/CT clear no evidence of SV involvement with PSA 6) My usual lab have been reporting my PSA as <0.01 ug/L since RT 18 months ago. My first 3 month testosterone is 0.8 nmol/L (23 ng/dL) and my PSA <0.03 ! Why is it
SimMartin
in
Advanced Prostate Cancer
1 month ago
covid with ADT
Completed my Prostate radiation treatments on July 11. I am on ADT (Orgovyx, Abiraterone, prednisone), and Flomax. The ADT will coninue for at least 2 years. Last week, tested positive for Covid; put on Paxlovid- was advised to stop Flomax while on Paxlovid. Continuing with the other meds. Was told,
Completed my Prostate radiation treatments on July 11. I am on ADT (Orgovyx, Abiraterone, prednisone), and Flomax. The ADT will coninue for at least 2 years. Last week, tested positive for Covid; put on Paxlovid- was advised to stop Flomax while on Paxlovid. Continuing with the other meds. Was told,
Sushupthi
in
Advanced Prostate Cancer
1 month ago
Zytiga & prednisone.
Hello Everyone, This is about my Father, he was on Nubeqa and Eligard shot for last two years. His PSA started going up again and his pains also started. His medical oncologist changed his Oral drug to Zytiga with prednisone. He is told not to eat anything two hours before and one hour after Zytiga
Hello Everyone, This is about my Father, he was on Nubeqa and Eligard shot for last two years. His PSA started going up again and his pains also started. His medical oncologist changed his Oral drug to Zytiga with prednisone. He is told not to eat anything two hours before and one hour after Zytiga
Szdnizam3
in
Advanced Prostate Cancer
2 months ago
Circulating Lipid Profiles Associated With Resistance to Androgen Deprivation Therapy in Localized Prostate Cancer
Circulating Lipid Profiles Associated With Resistance to Androgen Deprivation Therapy in Localized Prostate Cancer Authors: Hui-Ming Lin, PhD https://orcid.org/0000-0003-4892-6008, Xiaoyu Yang, MS https://orcid.org/0009-0001-0035-9289, Margaret M. Centenera, PhD https://orcid.org/0000-0002-2206-0632
Circulating Lipid Profiles Associated With Resistance to Androgen Deprivation Therapy in Localized Prostate Cancer Authors: Hui-Ming Lin, PhD https://orcid.org/0000-0003-4892-6008, Xiaoyu Yang, MS https://orcid.org/0009-0001-0035-9289, Margaret M. Centenera, PhD https://orcid.org/0000-0002-2206-0632
podsart
in
Advanced Prostate Cancer
2 months ago
At what PSA will a PSMA PET scan be useful?
Hi everyone My father has been on Lupron for 3 years now. We stopped Abi last year due to rising blood sugar levels. His PSA used to hover between 0.6-0.8 (with an occasional spike to 1.2). PSA in May 24 was 0.6. Today, however, his PSA came back as 2.5. Plan is to restart Abi and monitor. But I wanted
Hi everyone My father has been on Lupron for 3 years now. We stopped Abi last year due to rising blood sugar levels. His PSA used to hover between 0.6-0.8 (with an occasional spike to 1.2). PSA in May 24 was 0.6. Today, however, his PSA came back as 2.5. Plan is to restart Abi and monitor. But I wanted
Rodeoz15
in
Advanced Prostate Cancer
2 months ago
excuse me asking. Brain fog.
Just a quickie, and excuse me for treading over old ground. Re starting Tapering , from 10 . My Dr called me whilst I was away, for an update on my Cancer Op, how was I feeling etc……. Mentioned to him about going back onto Pred, due to my fingers & hands . Long story short, wanted me to try and taper
Just a quickie, and excuse me for treading over old ground. Re starting Tapering , from 10 . My Dr called me whilst I was away, for an update on my Cancer Op, how was I feeling etc……. Mentioned to him about going back onto Pred, due to my fingers & hands . Long story short, wanted me to try and taper
Stifffingers
in
PMRGCAuk
1 year ago
whenever i raise euthyrox100mg i get hbp headache nausea
is two weeks now i raised euthyrox from 75 yo 100mg and i dont think i can tolerate twice i tried and got hbp that even pills dont take it down
is two weeks now i raised euthyrox from 75 yo 100mg and i dont think i can tolerate twice i tried and got hbp that even pills dont take it down
morcan54
in
Thyroid UK
5 months ago
How long can I delay my Lupron shot ?
I am a stage 4 PC patient diagnosed in August 2021 and have been on ADT double therapy ever since.I get Lupron shots every 3 months and take 2 tablets of Apalutamide (Erleada ) evey day. I have been lucky that I responded well to the treatment and have been undetectable ever since. I
I am a stage 4 PC patient diagnosed in August 2021 and have been on ADT double therapy ever since.I get Lupron shots every 3 months and take 2 tablets of Apalutamide (Erleada ) evey day. I have been lucky that I responded well to the treatment and have been undetectable ever since. I
mynacho
in
Advanced Prostate Cancer
2 months ago
Recurrent prostate cancer at 5 months after radical prostatectomy, with psa up to 0.2. PSMA and MRI negative. Now on Leuprolide and Nubeqa.
My Gleason was 9. Incontinence has been an issue since the RP and even though it has improved still leaked around 30 ml a day. Delaying radiation that I was recommended by one institution but some Oncologists say to delay radiation for more recovery. Even though my PSA is 0.01 on the meds, i worry
My Gleason was 9. Incontinence has been an issue since the RP and even though it has improved still leaked around 30 ml a day. Delaying radiation that I was recommended by one institution but some Oncologists say to delay radiation for more recovery. Even though my PSA is 0.01 on the meds, i worry
Chipichape1
in
Advanced Prostate Cancer
2 months ago
bone Mets!
it’s here. After 11 1/2 years on zoladex injections and Xtandi followed by Nubeqa, husband had a PET scan that shows numerous spots on spine, breastbone and one lymph node in groin. PSA was undetectable for years, then .1 and .2, which triggered the order for the scan. The PA told him he has 1-2years
it’s here. After 11 1/2 years on zoladex injections and Xtandi followed by Nubeqa, husband had a PET scan that shows numerous spots on spine, breastbone and one lymph node in groin. PSA was undetectable for years, then .1 and .2, which triggered the order for the scan. The PA told him he has 1-2years
Nubeqa22
in
Advanced Prostate Cancer
2 months ago
Heading to Oncologist for 3month testing and tratment
Heading to Dr. for my quarterly shot of Eligard. I am also on apalutamide as part of a two year trial . I am a year and a half into treatments, including Brachytherapy and EBRT. I have tested < .04 psa for 6 months now despite initial diagnosis of Gleason 9. Everything seems to be gong according to
Heading to Dr. for my quarterly shot of Eligard. I am also on apalutamide as part of a two year trial . I am a year and a half into treatments, including Brachytherapy and EBRT. I have tested < .04 psa for 6 months now despite initial diagnosis of Gleason 9. Everything seems to be gong according to
68Guitar
in
Advanced Prostate Cancer
2 months ago
First PSMA PET scan and aftermath
My oncologists (medical and radiation) had been pushing me to have a PSMA scan for two years. Even though in 2023 my PSA rose from .67 to 1.37, I pointed out that a PSMA scan would not change my treatment. We ran another Axumin PET in January, which was stable, if not better, than the one in September
My oncologists (medical and radiation) had been pushing me to have a PSMA scan for two years. Even though in 2023 my PSA rose from .67 to 1.37, I pointed out that a PSMA scan would not change my treatment. We ran another Axumin PET in January, which was stable, if not better, than the one in September
dhccpa
in
Advanced Prostate Cancer
2 months ago
Will crabs save us? Crab-shaped DNA tetrahedral nanomachine for silencing undruggable mRNA targets in prostate cancer in vivo and in vitro
well…what is there to say?? Nano bots that seem to be able to silence some important proteins! Important for prostate cancer of course! https://www.sciencedirect.com/science/article/pii/S1748013224000422
well…what is there to say?? Nano bots that seem to be able to silence some important proteins! Important for prostate cancer of course! https://www.sciencedirect.com/science/article/pii/S1748013224000422
Maxone73
in
Advanced Prostate Cancer
2 months ago
Levo dose advice during IVF cycle - impact of HRT
Hello again 🙂 I’m wondering if anyone has any insight on the impact of HRT on Levo - Estrogen & Progesterone specifically which are the medications given during a Frozen Embryo Transfer cycle. NICE says there is anecdotal evidence of a moderate interaction between the medications. The progesterone
Hello again 🙂 I’m wondering if anyone has any insight on the impact of HRT on Levo - Estrogen & Progesterone specifically which are the medications given during a Frozen Embryo Transfer cycle. NICE says there is anecdotal evidence of a moderate interaction between the medications. The progesterone
StormsPass
in
Thyroid UK
2 months ago
krill oil
I have been taking krill oil for quite a while now for my locally advanced prostate cancer, but now I have been reading that it's not good for p/c,any thoughts anyone.
I have been taking krill oil for quite a while now for my locally advanced prostate cancer, but now I have been reading that it's not good for p/c,any thoughts anyone.
Radars
in
Advanced Prostate Cancer
2 months ago
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