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Non metastasis castrate resistant
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
Sailameme
in
Advanced Prostate Cancer
6 months ago
Addison's disease
Spoke with my GP yesterday regarding the extreme fatigue & rollercoaster of crashing following activity. He is now going to test & look at the possibility of Addison's. How does this mesh with PMR and Pred? I'd welcome any advice or better knowledge. Thanks.
Spoke with my GP yesterday regarding the extreme fatigue & rollercoaster of crashing following activity. He is now going to test & look at the possibility of Addison's. How does this mesh with PMR and Pred? I'd welcome any advice or better knowledge. Thanks.
Naim1
in
PMRGCAuk
28 days ago
Excess Folic Acid and Vitamin B12 Deficiency: Clinical Implications?
This is a very recent paper. Some of the areas covered are well-known. Such as not treating B12 deficiency with folic acid. But, in the more speculative parts, I think it does raise questions over the prescribing of high dose (e.g. 5 milligrams a day) of folic acid in those who are currently low in
This is a very recent paper. Some of the areas covered are well-known. Such as not treating B12 deficiency with folic acid. But, in the more speculative parts, I think it does raise questions over the prescribing of high dose (e.g. 5 milligrams a day) of folic acid in those who are currently low in
helvella
in
Pernicious Anaemia Society
28 days ago
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Do you think I need an increase in my T4 dose???
Hi all, I have hashimoto and hypo since many years. I take T4 medication ( 100 mg) every morning. The brand name is Euthyrox ( the version which has mannitol and citric acid instead of lactose). This is my thyroid test results after 14 months of no tests at all due to lack of medical insurance. I was
Hi all, I have hashimoto and hypo since many years. I take T4 medication ( 100 mg) every morning. The brand name is Euthyrox ( the version which has mannitol and citric acid instead of lactose). This is my thyroid test results after 14 months of no tests at all due to lack of medical insurance. I was
Gigihadad
in
Thyroid UK
6 months ago
Examining Prostate Cancer Survival Outcomes by Patient Age and Treatment Type in Patients with mHSPC
“the research suggests a differential impact between androgen receptor antagonists (like enzalutamide, apalutamide, and darolutamide) and androgen synthesis inhibitors (such as abiraterone), with antagonists showing a more pronounced benefit” https://www.urotoday.com/video-lectures/asco-gu-2024/video
“the research suggests a differential impact between androgen receptor antagonists (like enzalutamide, apalutamide, and darolutamide) and androgen synthesis inhibitors (such as abiraterone), with antagonists showing a more pronounced benefit” https://www.urotoday.com/video-lectures/asco-gu-2024/video
Maxone73
in
Advanced Prostate Cancer
6 months ago
Decompensated liver
good morning everyone.looking for information on what to expect.my brother has been diagnosed with Decompensated liver disease after many years of heavy drinking, he’s now a severe alcoholic, He was admitted into hospital 6 weeks ago with all the symptoms of liver disease, he was kept in for Five weeks
good morning everyone.looking for information on what to expect.my brother has been diagnosed with Decompensated liver disease after many years of heavy drinking, he’s now a severe alcoholic, He was admitted into hospital 6 weeks ago with all the symptoms of liver disease, he was kept in for Five weeks
tomgill
in
British Liver Trust
6 months ago
New diagnosis - what to expect/demand from GP
I had my second child in August 2022 and to be honest I've not felt right since. Since going back to work in June last year I've been permanently exhausted but it's just got worse and worse. Totally mental fog, can't focus, constantly yawning my head off. My body aches constantly but all the while I
I had my second child in August 2022 and to be honest I've not felt right since. Since going back to work in June last year I've been permanently exhausted but it's just got worse and worse. Totally mental fog, can't focus, constantly yawning my head off. My body aches constantly but all the while I
Whatdidyousay
in
Thyroid UK
1 month ago
Just some new Information about AI
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
chefjlu
in
Advanced Prostate Cancer
6 months ago
Morgentaler Saturation Model: PSA vs Testosterone - Estrogen Patch vs Lupron ADT
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
janebob99
in
Advanced Prostate Cancer
6 months ago
PSA vs Testosterone at high T levels - Linear Model
This is a plot of PSA versus Testosterone in men with prostate cancer. The blue points are taken from a YouTube video lecture by A. Morgentaler (2020). https://www.youtube.com/watch?v=wafNZV-Hkqk The green point is from Safraidi (2022): https://oamjms.eu/index.php/mjms/article/view/9388 Note the
This is a plot of PSA versus Testosterone in men with prostate cancer. The blue points are taken from a YouTube video lecture by A. Morgentaler (2020). https://www.youtube.com/watch?v=wafNZV-Hkqk The green point is from Safraidi (2022): https://oamjms.eu/index.php/mjms/article/view/9388 Note the
janebob99
in
Advanced Prostate Cancer
6 months ago
Thyroid disease link with lupus and fibromyalgia
Hello I need to try to understand about my current situation I have underactive thyroid for which I’m prescribed levothyroxine But I have told my drs about feeling so wiped out so tired it hurts falling asleep during the day but not sleeping through the night I have been diagnosed with atrial
Hello I need to try to understand about my current situation I have underactive thyroid for which I’m prescribed levothyroxine But I have told my drs about feeling so wiped out so tired it hurts falling asleep during the day but not sleeping through the night I have been diagnosed with atrial
Dogsareangels
in
Thyroid UK
1 month ago
PMR/GCA and Sjogrens disease
Does anyone have Sjogren’s disease along with PMR/CGA? For months I’ve been struggling with worsening vision in my left eye, and trying to figure out if I was having a flare. The left eye vision is like it was before cataract surgery, worse some times than others, especially after reading. Opthomologist
Does anyone have Sjogren’s disease along with PMR/CGA? For months I’ve been struggling with worsening vision in my left eye, and trying to figure out if I was having a flare. The left eye vision is like it was before cataract surgery, worse some times than others, especially after reading. Opthomologist
Mstiles
in
PMRGCAuk
1 month ago
Gluten and B12 deficiency
Is there a link between B12 deficiency and gluten sensitivity? My neuropathy has massively improved since I started self injecting regularly but I’ve noticed it returns slightly after eating bread, pasta or other foods containing gluten. Alcohol has an effect too I think. Trying to put the pieces of
Is there a link between B12 deficiency and gluten sensitivity? My neuropathy has massively improved since I started self injecting regularly but I’ve noticed it returns slightly after eating bread, pasta or other foods containing gluten. Alcohol has an effect too I think. Trying to put the pieces of
Alilev
in
Pernicious Anaemia Society
1 month ago
Hello, any help welcome
Hi all,I've been told I have an underactive thyroid recently after feeling very tired and achy for a few months, and having a blood test. No treatment as yet, seems more tests are to follow. I've become much more tired, a bit weepy ( not like me at all😔). And, horror of horrors, I'm gaining weight
Hi all,I've been told I have an underactive thyroid recently after feeling very tired and achy for a few months, and having a blood test. No treatment as yet, seems more tests are to follow. I've become much more tired, a bit weepy ( not like me at all😔). And, horror of horrors, I'm gaining weight
cheeseandonioncrisps
in
Thyroid UK
1 month ago
PSMA Scan to be scheduled - thank you Tall Allen
I want to thank Tall Allen for his suggestion that I see an oncologist. I had a RP followed by radiation in 2013. My PSA was undetectable until 2021, when it started to rise. This week I saw a radiation oncologist (whom I found through a friend) to ask him a lot of questions and to get his advice.
I want to thank Tall Allen for his suggestion that I see an oncologist. I had a RP followed by radiation in 2013. My PSA was undetectable until 2021, when it started to rise. This week I saw a radiation oncologist (whom I found through a friend) to ask him a lot of questions and to get his advice.
Geno2853
in
Advanced Prostate Cancer
6 months ago
Sarcoidosis
Hi I have Lupus and a few other auto diseases , just a quick question is Sarcoidosis any relation and do any of you have it , 💕
Hi I have Lupus and a few other auto diseases , just a quick question is Sarcoidosis any relation and do any of you have it , 💕
whatsit
in
LUPUS UK
1 month ago
A Celebration of Life
Good morning or afternoon! I've mentioned in some other posts that almost 19 years ago I had a liver transplant. I have done well and feel these 19 years added to my life are such a gift. Shortly after I retired from nursing I began volunteering my time at MidAmerica Transplant. This is a local (St
Good morning or afternoon! I've mentioned in some other posts that almost 19 years ago I had a liver transplant. I have done well and feel these 19 years added to my life are such a gift. Shortly after I retired from nursing I began volunteering my time at MidAmerica Transplant. This is a local (St
DonnaBoll
Administrator
in
PBC Foundation
6 months ago
cortisol/underactive thyroid
Out of interest, if your cortisol is high in the morning, would taking your levothyroxine in the morning make you feel even more stressed/twitchy?
Out of interest, if your cortisol is high in the morning, would taking your levothyroxine in the morning make you feel even more stressed/twitchy?
Puddingym
in
Thyroid UK
4 months ago
who also has fibromyalgia and then lupus?
I was diagnosed with fibromyalgia in 2009 and then lupus last year. I think it was harder to get the diagnosis because a lot of syptoms overlap.
I was diagnosed with fibromyalgia in 2009 and then lupus last year. I think it was harder to get the diagnosis because a lot of syptoms overlap.
Cazpurple
in
LUPUS UK
1 month ago
New to the scene
Hello, I’ve just signed up after probably a year of avoiding doing so, really hoping to connect with some people who understand rheumatoid arthritis and how to navigate it alongside the health system 🦓🐘🦒
Hello, I’ve just signed up after probably a year of avoiding doing so, really hoping to connect with some people who understand rheumatoid arthritis and how to navigate it alongside the health system 🦓🐘🦒
LoveIslandFan
in
NRAS
1 month ago
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