Experiences with

Canavan disease

Hello everyone! I hope you are doing well. I wanted to post an update about my father's current situation. After PSA started to raise, the MO added Abiraterone 1000 mg. a day with 10 mg prednisolone to his treatment regimen with Zoladex (once every 3 month) and Zoledronic acid (once every month). Abiraterone

Hi all, I am new to the forum and just looking for some clarity from someone who has more of an understanding from their own experience. After countless hours of googling trying to work out what’s going on with my mum’s recent diagnosis and worrying myself sick, I feel even more confused than ever

Hey, Max73. You missed one . . . and one right up your AI alley! [i]Salcudean and Bashashati[/i][i]: "In general, AI tools learn from prior examples, so there can always be a question whether the results generalized correctly. Continuous re-training and improvement as we accumulate more data

Would be so grateful for your help. When PMR hit in February 2023 thought I’d be off steroids in a couple weeks how foolish was I….. Prescribed Prednisolone 20mg February 2023 tapered to 10mg 3 weeks later, GP didn’t give instruction and I didn’t understand but it worked.. At some point was changed

Hi to all on the forum. I am a regular poster on the atrial fibrillation forum. The consultant I spoke to this morning said I have A (band) liver damage. I of course asked Doctor Google (He's full of doom and gloom). However, this seems to be the first stage showing a fatty liver. I asked what the prognosis

friends,At what PSA level to have PSMA PETCT if your PSA doubling time is less than a month and beginning of CRPC. PSA is 0.224 now.thanks.

another door opens, hopefully a good one… Researchers found that high expression of the PPP1CA gene is linked to a worse prognosis for patients. They discovered that silencing PPP1CA made cancer cells more susceptible to abiraterone, while overexpressing it had the opposite effect. This suggests that

The FDA has accepted a supplemental New Drug Application (sNDA) for darolutamide (Nubeqa) in combination with androgen deprivation therapy (ADT) for the treatment of patients with metastatic hormone-sensitive prostate cancer (mHSPC). This sNDA is based on positive results from the phase 3 ARANOTE

AC Immune’s stock jumps after Parkinson’s therapy shows signs of benefit - ACI-7104.056 https://www.msn.com/en-us/health/other/ac-immune-s-stock-jumps-after-parkinson-s-therapy-shows-signs-of-benefit/ar-AA1uaIvg AC Immune’s stock price has jumped by more than 20% after all patients in a trial of its

The validity of tests using fingerprick blood samples has long been questioned. Some claiming they are unusably awful. Others claiming tests are as good as those done on venous blood. It is good to see a paper which has researched the questions. Unfortunately, while they did include TSH, they did not

Hi I'm very new to this and just looking for advise and support .I had bloods 3 months ago and my liver function tests were higher than they should be. I had some more done yesterday and this time they have gone up quite sharply .. The serum alanine is 4x what it should be .. The gp office rang and has

The AMPLITUDE clinical trial (NCT04497844) is evaluating the effectiveness of Akeega, a combination of the PARP inhibitor niraparib and abiraterone acetate, along with prednisone, for treating metastatic castration-sensitive prostate cancer (mCSPC). This combination therapy is being compared to the

I am a bit slow, I am in Poland for work so I have to carve in the time to post. Mevrometostat (PF-06821497) is an experimental drug being investigated in a Phase III trial (NCT06551324) called MEVPRO-1. This trial is for men with metastatic castration-resistant prostate cancer (mCRPC) who have received

I am interested in your opinions as to who are the top 5 prostate oriented oncologists in the US. I would appreciate your opinions Thanks

Hi all,I had RT about 2 years ago and have been having 3 monthly Lupron jabs. My PSA has been rising steadily from a low of 0.02 ug/l (May, 2024) to 0.04 ug/l (August, 2024) The result of my blood test today is 0.09 ug/l (Nov, 2024). My PSA seems to be doubling every 3 months. Is this cause

Steage 4, gleason 9, 49 at diagnosis pelvice mets and possibly more mets. Only signs were urinating blood guys n gore... 2.5ish years into adt, did chemo, dit radio therapy. PSA went from 20 to under 0.1 but as soon as went down it's only ever risen Slowly but constantly. This week I'm urinating blood

I am delighted to announce that our next NoSilverBullet Zoom webinar will be taking place at 7.30pm London time on Monday, the 16th of December. I will have the pleasure of interviewing Dr Ray Dorsey on the topic of “Preventing Parkinson's Disease”. Dr Ray Dorsey is a professor of neurology and director

I saw an article on Web MD that referenced from many studies positive effects of creatine on Parkinson's - everything from balance to tiredness and musclewasting (sarcopenia) in older adults. Has anyone tried it? What dosage? Combined with what other supplements / drugs?

Just had bloodwork done which shows 5 slow consecutive rises in PSA - latest is 0.7, so still very minor. But the predictable continuous rise with a PSA doubling time now of about 6.4 months. Heres my updated graph with PSA on the y axis on a log scale, and time on the X axis with 3 month intervals.

I was having stomach pain for a long time so GP sent me for an ultrasound scan. The radiologist said my liver looked bright red, he then said I have fatty liver but that is nothing to worry about and very common but that didn't reassure me, after all cancer is very common. He asked if I took a lot of