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Canagliflozin / Metformin
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COVID survivors may be at a greater risk of developing Parkinson’s–like symptoms, researchers warn. What to know to protect your health
COVID survivors may be at a greater risk of developing Parkinson’s disease–like symptoms, researchers warn. What you need to know to protect your health
https://finance.yahoo.com/news/covid-survivors-may-greater-risk-170451040.html "The virus was able to infect cells from all the aforementioned
COVID survivors may be at a greater risk of developing Parkinson’s disease–like symptoms, researchers warn. What you need to know to protect your health
https://finance.yahoo.com/news/covid-survivors-may-greater-risk-170451040.html "The virus was able to infect cells from all the aforementioned
Bolt_Upright
in
Cure Parkinson's
5 months ago
Tips for conceiving with PCOS?
Me and my boyfriend have been trying for a baby for almost a year and I’ve recently been diagnosed with PCOS and prescribed metformin. We’re feeling positive and hopeful but just wanted to ask if anyone had any tips that you think that helped you to fall pregnant naturally?
Me and my boyfriend have been trying for a baby for almost a year and I’ve recently been diagnosed with PCOS and prescribed metformin. We’re feeling positive and hopeful but just wanted to ask if anyone had any tips that you think that helped you to fall pregnant naturally?
Healthyhan
in
PCOS UK (Verity)
5 months ago
Feeling lost
I am 34 and my husband is 45 and we meet 6 years ago, we got married 2 years later and started trying for a baby. Pretty much straight away. We are now 4 years into our journey, after 2 years trying on our own we started seeing a fertility specialist. At first i thoguht the problwm was with me as
I am 34 and my husband is 45 and we meet 6 years ago, we got married 2 years later and started trying for a baby. Pretty much straight away. We are now 4 years into our journey, after 2 years trying on our own we started seeing a fertility specialist. At first i thoguht the problwm was with me as
CRECHE12
in
More To Life
5 months ago
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randomized NHS clinical study on metformin and Li-Fraumeni Syndrome, which attacks TP53 gene
is started yesterday, we will see if against LFS we will have some data soon. I hope it will work https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/metformin-in-lfs-mili-trial/ https://www.tp53.co.uk
is started yesterday, we will see if against LFS we will have some data soon. I hope it will work https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/metformin-in-lfs-mili-trial/ https://www.tp53.co.uk
Maxone73
in
Fight Prostate Cancer
5 months ago
Diabetes (T2) in relation to Psoriatic Arthritis
Hi all, hope everyone is coping with the very cold weather. Has anyone experience of these two illnesses and drugs causing one or both to worsen? My diet is pretty much under control and not changed. I’ve also managed to lose almost a stone in weight but my morning blood readings are going up…
Hi all, hope everyone is coping with the very cold weather. Has anyone experience of these two illnesses and drugs causing one or both to worsen? My diet is pretty much under control and not changed. I’ve also managed to lose almost a stone in weight but my morning blood readings are going up…
farjer121
in
NRAS
5 months ago
Overwhelmed, what do I do next? Mutations In my Germline & a Tier 1 ATM Frameshift Alteration
My Germline is I’m missing a blm copy like a bloom syndrome drop My Genomic Tier 1 is a ATM Frameshift Alteration I have a battery of mutations listed in my profile bio. My PSA in the last 4 months is rising from <0.06 in October to 0.46 last week. I’m on Firmagon monthly, Zytiga with Prednisone
My Germline is I’m missing a blm copy like a bloom syndrome drop My Genomic Tier 1 is a ATM Frameshift Alteration I have a battery of mutations listed in my profile bio. My PSA in the last 4 months is rising from <0.06 in October to 0.46 last week. I’m on Firmagon monthly, Zytiga with Prednisone
Shorehousejam
in
Advanced Prostate Cancer
5 months ago
Not about PCa but interesting: GLP-1 Receptor Agonists help with colorectal cancer
"A research letter recently published in JAMA Oncology has provided some promising insights into the potential of Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) in lowering the risk of colorectal cancer (CRC) among patients with type 2 diabetes. The study involved a national retrospective analysis
"A research letter recently published in JAMA Oncology has provided some promising insights into the potential of Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) in lowering the risk of colorectal cancer (CRC) among patients with type 2 diabetes. The study involved a national retrospective analysis
Maxone73
in
Fight Prostate Cancer
5 months ago
Been on Firmagon with Zytiga and Prednisone PSA rising, what can I do next?
Information in Bio Hoping to try a PARP inhibitor or Provenge perhaps, I don’t know much about this, but my medical oncologist keeps mentioning pluvicto, I’m not interested in doing that yet. Information from Bio below: Diagnosed 07/01/2022 Diagnosed By PSA Score 942.40 06/24-2022-07/06/2022
Information in Bio Hoping to try a PARP inhibitor or Provenge perhaps, I don’t know much about this, but my medical oncologist keeps mentioning pluvicto, I’m not interested in doing that yet. Information from Bio below: Diagnosed 07/01/2022 Diagnosed By PSA Score 942.40 06/24-2022-07/06/2022
Shorehousejam
in
Advanced Prostate Cancer
5 months ago
Piqray/Alpelisib (plus Fulvestrant injections) Trial so far
Hello everyone. From Stevie and me. Just popping in to let you all know that I am nearly 2 months into my Piqray journey. (The trial is called CAPTURE here in Melbourne) After having a terrible, terrible slump when I came off 5 1/2 years of Ibrance and Anastrozole, due to new mets in my liver, after
Hello everyone. From Stevie and me. Just popping in to let you all know that I am nearly 2 months into my Piqray journey. (The trial is called CAPTURE here in Melbourne) After having a terrible, terrible slump when I came off 5 1/2 years of Ibrance and Anastrozole, due to new mets in my liver, after
Timtam56
in
SHARE Metastatic Breast Cancer
5 months ago
My blood sugar is 254mg/dl after 1 hour of lunch
I had a lunch at 1 pm. It included one bowl (100gm) of white rice, sambar, a small cup of potato fry, another cup of vegetables, and 200ml of buttermilk. I took metformin 500mg before lunch and went for a 2km walk inside my office. Took a random blood sugar at 2:30 pm and was shocked to see the reading
I had a lunch at 1 pm. It included one bowl (100gm) of white rice, sambar, a small cup of potato fry, another cup of vegetables, and 200ml of buttermilk. I took metformin 500mg before lunch and went for a 2km walk inside my office. Took a random blood sugar at 2:30 pm and was shocked to see the reading
secretsubject
in
Diabetes India
6 months ago
canagliflozin hope?
just read that this drug can help Lupus sufferers. Anyone know anything other than the basics? It is reported to help with arthritis pain, works on T cells so infections won’t necessarily cause our bodies to turn against us. Used for type 2 diabetes, it works in the kidneys, so not for everyone, and
just read that this drug can help Lupus sufferers. Anyone know anything other than the basics? It is reported to help with arthritis pain, works on T cells so infections won’t necessarily cause our bodies to turn against us. Used for type 2 diabetes, it works in the kidneys, so not for everyone, and
cobsie
in
LUPUS UK
10 months ago
Low dosage metformin: in vitro study
So...before my brain melts for good, I understand that low dosage is ok to affect cells proliferation? https://pubs.acs.org/doi/10.1021/acsptsci.3c00298
So...before my brain melts for good, I understand that low dosage is ok to affect cells proliferation? https://pubs.acs.org/doi/10.1021/acsptsci.3c00298
Maxone73
in
Fight Prostate Cancer
6 months ago
Metformin reduced Long Covid
Metformin is an old but well established diabetes drug. This study found a substantial benefit with metformin to prevent long covid. The attached plot shows this 41% reduction. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00299-2/fulltext And up to 63% if taken in time:
Metformin is an old but well established diabetes drug. This study found a substantial benefit with metformin to prevent long covid. The attached plot shows this 41% reduction. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00299-2/fulltext And up to 63% if taken in time:
EPguy
in
MPN Voice
6 months ago
metformin
I’m 60yoF, partial hysterectomy years ago. After hysterectomy was dx hashimotos. On levothyroxine 75mcg, continuously wt gain despite walking 7-10 miles daily. Eat healthy most often as an educated nutritionist. I convinced my MD to try Metformin to see if any help. MD would only order 500 once daily
I’m 60yoF, partial hysterectomy years ago. After hysterectomy was dx hashimotos. On levothyroxine 75mcg, continuously wt gain despite walking 7-10 miles daily. Eat healthy most often as an educated nutritionist. I convinced my MD to try Metformin to see if any help. MD would only order 500 once daily
Manhatt
in
Thyroid UK
6 months ago
laser treatment nhs
I’m 33 and was diagnosed with Pcos last year… I’ve been taking metformin for the past year and my acne has completely cleared up which is great! I have issues with facial hair and was referred to get laser hair removal on the nhs I didn’t think it was making much of a difference until people around me
I’m 33 and was diagnosed with Pcos last year… I’ve been taking metformin for the past year and my acne has completely cleared up which is great! I have issues with facial hair and was referred to get laser hair removal on the nhs I didn’t think it was making much of a difference until people around me
ERD_008
in
PCOS UK (Verity)
6 months ago
GCA and type 2 diabetes
Hi all Warriors Since being on prednisone (since July 2023 at 60mg, now at l6mg) my A1C has slowly crept up. Had blood work yesterday and A1C is now at 7.1. I have been told by my rheumy this is steroid induced and will start going down as I taper. Even though I have been tapering by 1mg every 2
Hi all Warriors Since being on prednisone (since July 2023 at 60mg, now at l6mg) my A1C has slowly crept up. Had blood work yesterday and A1C is now at 7.1. I have been told by my rheumy this is steroid induced and will start going down as I taper. Even though I have been tapering by 1mg every 2
Groda
in
PMRGCAuk
6 months ago
Tiredness, fatigue from Dapagliflozin? Heart failure
Does anyone get seriously tired and/or fatigued soon after taking Dapagliflozin? Because I take many meds for the heart failure, I split morning and evening but take the dapa midday! And soon after on the afternoon is when I am super tired and fatigued which can bring on serious anxiety. I am not sure
Does anyone get seriously tired and/or fatigued soon after taking Dapagliflozin? Because I take many meds for the heart failure, I split morning and evening but take the dapa midday! And soon after on the afternoon is when I am super tired and fatigued which can bring on serious anxiety. I am not sure
theonethatgotaway1
in
British Heart Foundation
8 months ago
Pre-CRPC Supplements/Drugs - Potential Risks vs Rewards?
With some substances there could be a "tipping" point depending on the substance, the dosage and the patient's stage of cancer where the substance may have a higher chance of having a negative effect instead of positive. It usually relates to ROS levels. Adequate levels of ROS are important for cancer
With some substances there could be a "tipping" point depending on the substance, the dosage and the patient's stage of cancer where the substance may have a higher chance of having a negative effect instead of positive. It usually relates to ROS levels. Adequate levels of ROS are important for cancer
jazj
in
Advanced Prostate Cancer
6 months ago
Diabetes
When I lost 33lbs I found I was no longer in the Diabetic range. So it is possible and worthwhile! I no longer take Metformin. I have found I am not losing more weight for now despite still being quite restrictive in my diet. I have developed kidney stones which may be because I never ate much fat so
When I lost 33lbs I found I was no longer in the Diabetic range. So it is possible and worthwhile! I no longer take Metformin. I have found I am not losing more weight for now despite still being quite restrictive in my diet. I have developed kidney stones which may be because I never ate much fat so
DoctorRascal
2023 December
in
Weight Loss Support
6 months ago
ongoing issues
it’s been a tough month this weather is making the fibro non stop but in turn my RA has also kicked in within the joints so I am creaking away like an unoiled motor and even hubby went you need some calm weather! Trip to GP yesterday and he looked at me and said I know you have a lot going on what’
it’s been a tough month this weather is making the fibro non stop but in turn my RA has also kicked in within the joints so I am creaking away like an unoiled motor and even hubby went you need some calm weather! Trip to GP yesterday and he looked at me and said I know you have a lot going on what’
Deeb1764
in
NRAS
6 months ago
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