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Blood-coagulation factor XIII
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Hypothesis II
My hypothesis is that the antibody that attacks the intrinsic factor and or parietal cell may also bind to B12 rendering it unusable at the cellular level. That the production of the antibody with regards to amount is unknown and different at different times for the individual and different for each
My hypothesis is that the antibody that attacks the intrinsic factor and or parietal cell may also bind to B12 rendering it unusable at the cellular level. That the production of the antibody with regards to amount is unknown and different at different times for the individual and different for each
WIZARD6787
in
Pernicious Anaemia Society
5 months ago
Daughters blood results, advice please
15 year old daughter has been having lots of time off school. not ideal in yr 10 and now 11. I feel a bit guilty about it all, think I have dropped the ball on this one. She had digestion problems when small, had an umbilical hernia repaired about 2 1/2- 3 years then several years of issues, vomiting
15 year old daughter has been having lots of time off school. not ideal in yr 10 and now 11. I feel a bit guilty about it all, think I have dropped the ball on this one. She had digestion problems when small, had an umbilical hernia repaired about 2 1/2- 3 years then several years of issues, vomiting
Polo22
in
Pernicious Anaemia Society
6 months ago
How likely is it I have PA
Hello, I would appreciate some feedback on your own experiences of diagnosis. - 3 months ago I had a B12 level of <142 and a range of related symptoms - Full Blood count did not show an abnormalities but I was also deficient in ferritin. - I am 37 and have been diagnosed with hashimotos since I
Hello, I would appreciate some feedback on your own experiences of diagnosis. - 3 months ago I had a B12 level of <142 and a range of related symptoms - Full Blood count did not show an abnormalities but I was also deficient in ferritin. - I am 37 and have been diagnosed with hashimotos since I
Sparkleros
in
Pernicious Anaemia Society
6 months ago
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Does this sound like osteoarthritis - or something else?
Hi everyone, I wonder if I can please get some help. I’ve been experiencing widespread body pain for c.3 years. I initially put this down to the menopause and earlier this year I started to focus on my under active thyroid - I’m not yet optimally medicated for that (takes a while). In May I decided
Hi everyone, I wonder if I can please get some help. I’ve been experiencing widespread body pain for c.3 years. I initially put this down to the menopause and earlier this year I started to focus on my under active thyroid - I’m not yet optimally medicated for that (takes a while). In May I decided
J972
in
NRAS
6 months ago
Folic Acid does not cause PA
I saw this article with responses about the consumption of folic acid. What do people think about the responses? Especially the one who says that there shouldn't be a limit to the amount of folic acid taken. https://www.bmj.com/content/329/7479/1376/rapid-responses I have been taking 5mg folic acid
I saw this article with responses about the consumption of folic acid. What do people think about the responses? Especially the one who says that there shouldn't be a limit to the amount of folic acid taken. https://www.bmj.com/content/329/7479/1376/rapid-responses I have been taking 5mg folic acid
MEguy
in
Thyroid UK
6 months ago
So girding my loins, GP's in morning,
So have an appointment with GP at 11 am tomorrow. Now this was supposed to be about pain/discomfort ? RA. Of course they are bit sneaky and lots of other tests were included, but we aren't daft are we, we check first. So Thyroid bloods , TSH 0.01 (0.27-4.20) FT4 21.6 (12-22) as usual no FT3
So have an appointment with GP at 11 am tomorrow. Now this was supposed to be about pain/discomfort ? RA. Of course they are bit sneaky and lots of other tests were included, but we aren't daft are we, we check first. So Thyroid bloods , TSH 0.01 (0.27-4.20) FT4 21.6 (12-22) as usual no FT3
Polo22
in
Thyroid UK
6 months ago
Castor Oil Packs
Have any of you tried this? Was recommended to me by a natural therapist, she has a client who it really helped. Below are links to what they do. https://healf.com/blogs/health-journal/what-are-castor-oil-packs-how-do-they-work-and-what-do-they-do https://thewellnessjunction.com/the-benefits-of-using-castor-oil-packs-for-your-thyroid
Have any of you tried this? Was recommended to me by a natural therapist, she has a client who it really helped. Below are links to what they do. https://healf.com/blogs/health-journal/what-are-castor-oil-packs-how-do-they-work-and-what-do-they-do https://thewellnessjunction.com/the-benefits-of-using-castor-oil-packs-for-your-thyroid
Nomad12
in
Thyroid UK
3 days ago
lapararoscopy
I have a complex cyst probably 7.2-7.4cm and have been told that I will need eventual laparascopy. I am back 23rd of July again for another tvultrasound to check how it is. The gynae/surgeon has done watchful waiting with me since my diagnosis as he knows I am a carer for my mum and I have no one else
I have a complex cyst probably 7.2-7.4cm and have been told that I will need eventual laparascopy. I am back 23rd of July again for another tvultrasound to check how it is. The gynae/surgeon has done watchful waiting with me since my diagnosis as he knows I am a carer for my mum and I have no one else
Ova104
in
My Ovacome
4 days ago
Do those with thin linings have light periods?
Hello,I have unexplained infertility. Have had one failed cycle that produced 3 good quality blasts. 1 x fresh failed and 2 x FET both failed to implant. I had one cycle cancelled due to thin lining of 5.5mm. I now take additional estrogen, Viagra, Aspirin and progesterone which have given me a lining
Hello,I have unexplained infertility. Have had one failed cycle that produced 3 good quality blasts. 1 x fresh failed and 2 x FET both failed to implant. I had one cycle cancelled due to thin lining of 5.5mm. I now take additional estrogen, Viagra, Aspirin and progesterone which have given me a lining
AmyG18
in
Fertility Network UK
4 days ago
Learning and Careers with B12 Anemia
Hi everyone, I wanted to know what everyone studied and does for a living here. I am feeling down because I have not done well with college and keeping a job because of my anemia. I just want to know if anyone else went thru that, still is dealing with that, and/or is able to live a normal life. I
Hi everyone, I wanted to know what everyone studied and does for a living here. I am feeling down because I have not done well with college and keeping a job because of my anemia. I just want to know if anyone else went thru that, still is dealing with that, and/or is able to live a normal life. I
GreenTamales
in
Pernicious Anaemia Society
7 months ago
Any tips for Natural Modified FET (boost lining)?
Hi everyone, I have a persistent thinnish lining (around 6 to 7mm) after an episode of abnormal bleeding between periods (turned out to be silent endo and a polyp that did not show up on ultrasound). Before that, 11mm was my average. After failing a recent FET, my doctor decided to monitor my lining
Hi everyone, I have a persistent thinnish lining (around 6 to 7mm) after an episode of abnormal bleeding between periods (turned out to be silent endo and a polyp that did not show up on ultrasound). Before that, 11mm was my average. After failing a recent FET, my doctor decided to monitor my lining
hanzi
in
Fertility Network UK
1 month ago
Supporting Egg Quality
Hello All,We went through our first cycle of IVF in Jan and we are planning our next round in July. The first round we went in very naively and rather blind in terms of body/mind preparation. I have tried to guide myself as much as I can but I wondered what you could add to what I am doing. I am on
Hello All,We went through our first cycle of IVF in Jan and we are planning our next round in July. The first round we went in very naively and rather blind in terms of body/mind preparation. I have tried to guide myself as much as I can but I wondered what you could add to what I am doing. I am on
LuckyLazyLara
in
Fertility Network UK
2 months ago
Bit old fashioned...
I discovered that a castor oil pack really helps with knee pain. It's horrible sticky oil, but it works topically (for me at least). I have bad memories of this stuff from my childhood. Any hint of sickness and out came the bottle. I would not recommend injesting it! 🤮 it's better than the deep heat
I discovered that a castor oil pack really helps with knee pain. It's horrible sticky oil, but it works topically (for me at least). I have bad memories of this stuff from my childhood. Any hint of sickness and out came the bottle. I would not recommend injesting it! 🤮 it's better than the deep heat
Blackberrywine
in
NRAS
3 months ago
one last question ( hopefully)
I have finally managed to get an appointment with my GP where I hope to convince him to give me B12 injections more often that once every 8 weeks and I never had a loading doses so am hoping for that too. I hope I can get him to do some tests, like size shape and number of red blood cells, intrinsic
I have finally managed to get an appointment with my GP where I hope to convince him to give me B12 injections more often that once every 8 weeks and I never had a loading doses so am hoping for that too. I hope I can get him to do some tests, like size shape and number of red blood cells, intrinsic
totallyFrustrated
in
Pernicious Anaemia Society
7 months ago
Low B12 and ferritin questions
Over the past year I have had frequent respiratory infections and when not ill, I am always exhausted. I often need to stay in bed on my days off recovering. Alongside the exhaustion and frequent infections I have dealt with nausea and gastric problems which I always thought were due to IBS. I faint
Over the past year I have had frequent respiratory infections and when not ill, I am always exhausted. I often need to stay in bed on my days off recovering. Alongside the exhaustion and frequent infections I have dealt with nausea and gastric problems which I always thought were due to IBS. I faint
bakedbean5007
in
Pernicious Anaemia Society
2 days ago
High stomach pH
I have just done a second gut microbiome test. The first one I did in August last year showed I had a score of 7.2, which indicated I have little stomach acid. The one I have just done has come back higher at 8.1 (ideal range should be 5.8 - 6.5). Does anyone else have this? Is is a good indication
I have just done a second gut microbiome test. The first one I did in August last year showed I had a score of 7.2, which indicated I have little stomach acid. The one I have just done has come back higher at 8.1 (ideal range should be 5.8 - 6.5). Does anyone else have this? Is is a good indication
Chickens44
in
Pernicious Anaemia Society
7 days ago
some advice needed please
Hi I’m going to see Dr Klein in Cambridge as recommended by some of you guys, he has sent links to order theses products from Medisave Sharpsguard yellow 2.5ltr sharps bin professional 70% Alcohol IPA Pre- Injection Swabs x 100 BD Discardit 2 ml Concentric Tip Syringe 2 Piece x 100
Hi I’m going to see Dr Klein in Cambridge as recommended by some of you guys, he has sent links to order theses products from Medisave Sharpsguard yellow 2.5ltr sharps bin professional 70% Alcohol IPA Pre- Injection Swabs x 100 BD Discardit 2 ml Concentric Tip Syringe 2 Piece x 100
Windyway
in
Pernicious Anaemia Society
16 days ago
antibodies
Is it possible to have antibodies to parietal cells but not to intrinsic factor? I have no intrinsic factor.
Is it possible to have antibodies to parietal cells but not to intrinsic factor? I have no intrinsic factor.
Sissiotto
in
Pernicious Anaemia Society
7 months ago
Blood test results abnormal. But doctor says normal! How?
Last week I had some blood tests, however, once again, not all blood tests that were requested, were taken!!!I have results of some which are abnormal as follows.... Heaematocrit 0.483 0.37 - 9.47 abnormal Red Blood cell distribution width 16.3%
Last week I had some blood tests, however, once again, not all blood tests that were requested, were taken!!!I have results of some which are abnormal as follows.... Heaematocrit 0.483 0.37 - 9.47 abnormal Red Blood cell distribution width 16.3%
DandyButch
in
Thyroid UK
28 days ago
B12 injections stopped by gp after 5 years treatment on nhs
I was diagnosed with chronic b12 deficiency years ago - my GP started giving me injections every 3 months and my nurse told me that it was for life. I’ve always eaten meat my whole life - so my deficiency was not caused by diet. They have stated that my deficiency is due to malabsorption, but my intrinsic
I was diagnosed with chronic b12 deficiency years ago - my GP started giving me injections every 3 months and my nurse told me that it was for life. I’ve always eaten meat my whole life - so my deficiency was not caused by diet. They have stated that my deficiency is due to malabsorption, but my intrinsic
LaraPA
in
Pernicious Anaemia Society
1 month ago
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