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SPPORT trial: whole pelvic salvage radiation + short-term ADT after failed surgery can be a curative option
In contrast to a previous trial (RTOG 9601) that told us that ADT can be safely avoided if PSA<0.7, this trial suggests at least 4 months of ADT and whole pelvic treatment. The reason for the difference in recommendations is due to the choice of endpoint. SPPORT is telling us that if we are willing to
In contrast to a previous trial (RTOG 9601) that told us that ADT can be safely avoided if PSA<0.7, this trial suggests at least 4 months of ADT and whole pelvic treatment. The reason for the difference in recommendations is due to the choice of endpoint. SPPORT is telling us that if we are willing to
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
EVOLUTION - Trial for the treatment of mCRPC
Prostate cancer remains the most common cancer and the second commonest cause of cancer related death in Australian men. This week Peter MacCallum Cancer Centre in Melbourne screened it's first patient as it commences the EVOLUTION trial “We are on the verge of a complete transformation in prostate
Prostate cancer remains the most common cancer and the second commonest cause of cancer related death in Australian men. This week Peter MacCallum Cancer Centre in Melbourne screened it's first patient as it commences the EVOLUTION trial “We are on the verge of a complete transformation in prostate
marnieg46
in
Advanced Prostate Cancer
2 years ago
Once Hopeful Prostate Cancer Drug Fails Phase II Test
Does anyone have a list of the drugs that were fast tracked for PCa? Might be a good place to look for trials. "RV001 is an immuno-oncologic drug that presents to the immune system as an antigen. It works by stimulating the T-cells to spot and destroy cells that carry the RhoC protein, which is over-expressed
Does anyone have a list of the drugs that were fast tracked for PCa? Might be a good place to look for trials. "RV001 is an immuno-oncologic drug that presents to the immune system as an antigen. It works by stimulating the T-cells to spot and destroy cells that carry the RhoC protein, which is over-expressed
Scout4answers
in
Advanced Prostate Cancer
2 years ago
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PD and Botox in Urethra
On Wednesday, my pwp was given a Botox A injection into his urethra to stop spastic urine out put. Has anyone received this treatment? If this doesn’t work out, doctor is recommending implanting catheter in his navel which will collect urine and the port changed out monthly by a nurse.
On Wednesday, my pwp was given a Botox A injection into his urethra to stop spastic urine out put. Has anyone received this treatment? If this doesn’t work out, doctor is recommending implanting catheter in his navel which will collect urine and the port changed out monthly by a nurse.
Parkiewife
in
Cure Parkinson's
2 years ago
Rollercoaster 🎢 again!
Had my 1st meeting about starting chemo today so was happy to get a step closer! The oncologist told me that I'm still stage 3a hgs but they had read in 1 letter that a lymph was flagged up next to my heart!! 1st I've heard this as I'd had womb biopsy cervix and guided ct on lymph plus ct scan 6weeks
Had my 1st meeting about starting chemo today so was happy to get a step closer! The oncologist told me that I'm still stage 3a hgs but they had read in 1 letter that a lymph was flagged up next to my heart!! 1st I've heard this as I'd had womb biopsy cervix and guided ct on lymph plus ct scan 6weeks
Newbery3
in
My Ovacome
2 years ago
Should magnesium carbonate be avoided in thyroid disease …
… even though it’s widely recommended for gently relieving constipation, which many of us, including me lately, suffer from? It’s also commonly used as a neutraliser for acidic stomach conditions but lots of us have problems making enough stomach acid which is a contributory factor in constipation,
… even though it’s widely recommended for gently relieving constipation, which many of us, including me lately, suffer from? It’s also commonly used as a neutraliser for acidic stomach conditions but lots of us have problems making enough stomach acid which is a contributory factor in constipation,
Noelnoel
in
Thyroid UK
2 years ago
Gait issue and nerve compression
To all of you struggling with gate, see a neurologist if you haven't already. I had an ataxia gait and it was pretty bad. An MRI showed an arachnoid cyst in my spine from T1 to T10 that was compressing my spinal cord and thus the nerves, causing the issue. After removal I could walk a bit better and
To all of you struggling with gate, see a neurologist if you haven't already. I had an ataxia gait and it was pretty bad. An MRI showed an arachnoid cyst in my spine from T1 to T10 that was compressing my spinal cord and thus the nerves, causing the issue. After removal I could walk a bit better and
Clumsygirl
in
Meningitis Now
2 years ago
Cholera vaccine & Healthy Traveler bias?
New update on the cholera vaccine topic from the Karolinska Institutet. Sweden, [1] Cutting to the chase: "We showed that administration of cholera vaccine after prostate cancer diagnosis is associated with a significant reduction in mortality (HR 0.46 ...) even after adjusting for all known confounders
New update on the cholera vaccine topic from the Karolinska Institutet. Sweden, [1] Cutting to the chase: "We showed that administration of cholera vaccine after prostate cancer diagnosis is associated with a significant reduction in mortality (HR 0.46 ...) even after adjusting for all known confounders
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Recovering from a traumatic brain injury.
Hi all. I am currently 9 months into recovering from a massive brain trauma and have good days and bad but more worrying is that I am so intolerant and snappy at home with the people who have been there the most for me and look at a lot of things so negative rather than positive. I say to my self right
Hi all. I am currently 9 months into recovering from a massive brain trauma and have good days and bad but more worrying is that I am so intolerant and snappy at home with the people who have been there the most for me and look at a lot of things so negative rather than positive. I say to my self right
Golfer81
in
Headway
2 years ago
Ibs flare up
I've been having a lot of pain recently and last night I had to make two urgent trips to the bathroom where I had a lot of diarhea and stomach cramps the pain was excruciating. I didn't have to lie on the bathroom floor this time. Today my colon aches and is very sore the dicycloverine and paracetamol
I've been having a lot of pain recently and last night I had to make two urgent trips to the bathroom where I had a lot of diarhea and stomach cramps the pain was excruciating. I didn't have to lie on the bathroom floor this time. Today my colon aches and is very sore the dicycloverine and paracetamol
Hollings
in
IBS Network
2 years ago
New Trial: A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With MAST
As most here know, Immunotherapies have not so far proven to be especially effective in PCa. Here is info on a new viral agent that, while not targeting PCa specifically, is starting clinical trials focused on [i]"Metastatic or Advanced Solid Tumours (MAST)"[/i]. With 100 participants, it will hopefully
As most here know, Immunotherapies have not so far proven to be especially effective in PCa. Here is info on a new viral agent that, while not targeting PCa specifically, is starting clinical trials focused on [i]"Metastatic or Advanced Solid Tumours (MAST)"[/i]. With 100 participants, it will hopefully
cujoe
in
Fight Prostate Cancer
2 years ago
Mischley's diet and raw dairy?
Hi everyone! Have any of you been following Dr Laurie Mischley's diet recommendations, which include as the number 1 thing to do, to eliminate dairy? Has this helped you? I am wondering if it's not the dairy itself but what the cows are fed, other practices and how the milk is processed in conventional
Hi everyone! Have any of you been following Dr Laurie Mischley's diet recommendations, which include as the number 1 thing to do, to eliminate dairy? Has this helped you? I am wondering if it's not the dairy itself but what the cows are fed, other practices and how the milk is processed in conventional
PDFree
in
Cure Parkinson's
2 years ago
***Six months scans are back ***
Good morning my Brother, I got my six month scans back and all in all I'm very pleased with the results. CT scan shows no progression to any vital organs, or soft tissue. There has been no change from last scan six months ago. Bone scan shows very slight uptake to one met ,all other mets are stable
Good morning my Brother, I got my six month scans back and all in all I'm very pleased with the results. CT scan shows no progression to any vital organs, or soft tissue. There has been no change from last scan six months ago. Bone scan shows very slight uptake to one met ,all other mets are stable
leo2634
in
Advanced Prostate Cancer
2 years ago
Af breakthrough
Hi All Hope you are all keeping well I take Bisopolol 1.25 twice a day. After having the dreaded Covid about a month ago . I then had a uti which I was prescribed antibiotics I have taken the full course but they gave me diarrhoea.I’m just wondering if anyone else had more af episodes after an infection
Hi All Hope you are all keeping well I take Bisopolol 1.25 twice a day. After having the dreaded Covid about a month ago . I then had a uti which I was prescribed antibiotics I have taken the full course but they gave me diarrhoea.I’m just wondering if anyone else had more af episodes after an infection
exmouth
in
Atrial Fibrillation Support
2 years ago
Leukapheresis completed
I got my leukapheresis yesterday for the CAER-T trial at City of Hope. It should be about 4 weeks until they infuse the modified cells. Next steps are bone and marrow biopsies to characterize the cancer prior to treatment, chemotherapy to deplete my T cells and macrophages then infusing the modified
I got my leukapheresis yesterday for the CAER-T trial at City of Hope. It should be about 4 weeks until they infuse the modified cells. Next steps are bone and marrow biopsies to characterize the cancer prior to treatment, chemotherapy to deplete my T cells and macrophages then infusing the modified
Javelin18
in
Advanced Prostate Cancer
2 years ago
Bladder pain
I had bladder pain and frequency and went to a specialist as my GP did not want to prescribe more antibiotics and the labtest showed no infection. (I had had some a month or so before). In less than 10 minutes the specialist decided I had a persistent infection but also thought an alternative to antibiotics
I had bladder pain and frequency and went to a specialist as my GP did not want to prescribe more antibiotics and the labtest showed no infection. (I had had some a month or so before). In less than 10 minutes the specialist decided I had a persistent infection but also thought an alternative to antibiotics
Andann
in
IBS Network
2 years ago
Help
Hello all you kind folk, I wonder if anyone can give me any advice regarding Doxazosin, a medication for prostate problems, now I am female and am concerned That I will suddenly start an urge to go to the pub for a pint and call everyone mate! The medication is prescribed for my very high blood pressure
Hello all you kind folk, I wonder if anyone can give me any advice regarding Doxazosin, a medication for prostate problems, now I am female and am concerned That I will suddenly start an urge to go to the pub for a pint and call everyone mate! The medication is prescribed for my very high blood pressure
Hatten28
in
Atrial Fibrillation Support
2 years ago
Mixed news for flavonoids.
New meta-analysis below [1]. The flavonoid family (Anthocyanidins, Anthoxanthins, Flavanones, Flavanonols, Flavans, & Isoflavonoids) include members that have hormone-like properties. "This meta-analysis was aimed to explore the association between flavonoids intake and {hormone-related cancer} HRC
New meta-analysis below [1]. The flavonoid family (Anthocyanidins, Anthoxanthins, Flavanones, Flavanonols, Flavans, & Isoflavonoids) include members that have hormone-like properties. "This meta-analysis was aimed to explore the association between flavonoids intake and {hormone-related cancer} HRC
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Midgut malrotation
I had HIDA scan done for my gallbladder. In addition to the findings for gallbladder, report noted “midgut malrotation”. Doctor has asked for Ct scan to confirm. From what I have read online it sounds scary. It’s very rare in adult. Can anyone provide some insight on this?
I had HIDA scan done for my gallbladder. In addition to the findings for gallbladder, report noted “midgut malrotation”. Doctor has asked for Ct scan to confirm. From what I have read online it sounds scary. It’s very rare in adult. Can anyone provide some insight on this?
Jason2233
in
PMRGCAuk
2 years ago
Bladder infection
Hi, its possible I have a bladder infection on the way, I have been told if I have to take the antibiotics Ive been given I need to stop methotrexate and amgevita biologic. I have no idea what to expect in terms of how I may feel etc. I cant get hold of my rheumatology dept. So looking for anyones experience
Hi, its possible I have a bladder infection on the way, I have been told if I have to take the antibiotics Ive been given I need to stop methotrexate and amgevita biologic. I have no idea what to expect in terms of how I may feel etc. I cant get hold of my rheumatology dept. So looking for anyones experience
Bonnett121
in
NRAS
2 years ago
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