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Alendronate/fosamax part 2
In 2014, after taking alendonate for (?) 5+ years, my left femur broke as I walked down a very slight slope. I have a intramedullary pin running from hip to knee. In 2020, on March 3, after not taking AA for nearly 6 years, I stood up to get off the bus, and my right femur broke, same reason. Now
In 2014, after taking alendonate for (?) 5+ years, my left femur broke as I walked down a very slight slope. I have a intramedullary pin running from hip to knee. In 2020, on March 3, after not taking AA for nearly 6 years, I stood up to get off the bus, and my right femur broke, same reason. Now
BrancepethCastle
in
Bone Health and Osteoporosis UK
2 years ago
Hyaluronic acid treatment for damaged bladder
Hi guys finally getting some answers of what has been going on with my bladder. (Bleeding from it) Had a cystoscopy yesterday, after the usual embarrassing bits, I found it quite fascinating to see inside my bladder on the screen. She never gave me a diagnosis but looking at my past history it is probably
Hi guys finally getting some answers of what has been going on with my bladder. (Bleeding from it) Had a cystoscopy yesterday, after the usual embarrassing bits, I found it quite fascinating to see inside my bladder on the screen. She never gave me a diagnosis but looking at my past history it is probably
Dustyangel
in
Pelvic Radiation Disease Association
2 years ago
The Role Of Bile Acids In Prostate Cancer
Bile acids (BAs) belong to cholesterol-derived sterols. Due to the side chain carboxyl group and hydroxylation of their steroid ring they are more polar than cholesterol. They have an amphipatic character for which they are known as natural detergents. Majority of cholesterol is excreted by bile acids
Bile acids (BAs) belong to cholesterol-derived sterols. Due to the side chain carboxyl group and hydroxylation of their steroid ring they are more polar than cholesterol. They have an amphipatic character for which they are known as natural detergents. Majority of cholesterol is excreted by bile acids
Hidden
in
Advanced Prostate Cancer
2 years ago
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Dexascan and Alendronate 70mg
After six years continuously on lupron, I had scan done on April 1st. I was DX with osteopenia. Doctor wants me too take alendronate 70mg once a week, I have some concerns about the side effects. Anyone taking this drug and what was your side effects. Thank ET51
After six years continuously on lupron, I had scan done on April 1st. I was DX with osteopenia. Doctor wants me too take alendronate 70mg once a week, I have some concerns about the side effects. Anyone taking this drug and what was your side effects. Thank ET51
Echotango51
in
Advanced Prostate Cancer
2 years ago
What is going on??
Help. Don’t know who to contact if anyone. Could be I’m a Jessie! On Wednesday of last week my left foot started swelling (I have Lupus, Sjogrens and fibromyalgia with costochondritis). Then the next day the other foot was a bit puffy. On that day I travelled from Wales to Bedfordshire and then from
Help. Don’t know who to contact if anyone. Could be I’m a Jessie! On Wednesday of last week my left foot started swelling (I have Lupus, Sjogrens and fibromyalgia with costochondritis). Then the next day the other foot was a bit puffy. On that day I travelled from Wales to Bedfordshire and then from
Bowenlady
in
LUPUS UK
2 years ago
PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy
Here is one out of far left field https://www.frontiersin.org/articles/10.3389/fphar.2021.692574/full PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy www.frontiersin.orgSi-Min Qi1†, www.frontiersin.orgJinyun Dong2†, www.frontiersin.orgZhi-Yuan Xu2, www.frontiersin.orgXiang-Dong
Here is one out of far left field https://www.frontiersin.org/articles/10.3389/fphar.2021.692574/full PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy www.frontiersin.orgSi-Min Qi1†, www.frontiersin.orgJinyun Dong2†, www.frontiersin.orgZhi-Yuan Xu2, www.frontiersin.orgXiang-Dong
Scout4answers
in
Advanced Prostate Cancer
2 years ago
Glycyrrhizin in licorice root is a novel pharmacological inhibition of HMGB1 that repress prostate cancer metastasis
High mobility group box 1 (HMGB1) is upregulated in nearly every tumor type. Importantly, clinical evidence also proposed that HMGB1 is particularly increased in metastatic prostate cancer patients. Besides, a growing number of studies highlighted that HMGB1 could be a successful therapeutic target for
High mobility group box 1 (HMGB1) is upregulated in nearly every tumor type. Importantly, clinical evidence also proposed that HMGB1 is particularly increased in metastatic prostate cancer patients. Besides, a growing number of studies highlighted that HMGB1 could be a successful therapeutic target for
Hidden
in
Advanced Prostate Cancer
2 years ago
Osteoporosis
Good morning, I’ve now received a diagnosis of osteoporosis in my hips and spine following a DEXA scan 6 weeks ago. I have GCA diagnosed in April 2021 and have been reducing prednisolone from 60mg to currently 6mg. My rheumatologist wants me to take alendronic acid which I’m worried about. I wonder if
Good morning, I’ve now received a diagnosis of osteoporosis in my hips and spine following a DEXA scan 6 weeks ago. I have GCA diagnosed in April 2021 and have been reducing prednisolone from 60mg to currently 6mg. My rheumatologist wants me to take alendronic acid which I’m worried about. I wonder if
Avon14
in
PMRGCAuk
2 years ago
How A Banana Before Bed Can Help You Sleep Better
But did you know bananas can also help you sleep? It turns out; this beloved fruit is the perfect sleep aid. It provides several vitamins and minerals that can improve the quality of your sleep. Bananas reduce stress and anxiety, alleviate muscle cramps, and regulate your sleep-wake cycle with serotonin
But did you know bananas can also help you sleep? It turns out; this beloved fruit is the perfect sleep aid. It provides several vitamins and minerals that can improve the quality of your sleep. Bananas reduce stress and anxiety, alleviate muscle cramps, and regulate your sleep-wake cycle with serotonin
Thal
in
Cure Parkinson's
2 years ago
News that worried us and studies that gave us hope (04/2022).
This is the information that gave us hope while my father was alive and has given hope to many since then (March 2012). 1. News that worried us. In the coming decades the number of Parkinson's disease patients is feared to increase very worryingly, to double by 2030 (Dorsey 2007) and even to triple
This is the information that gave us hope while my father was alive and has given hope to many since then (March 2012). 1. News that worried us. In the coming decades the number of Parkinson's disease patients is feared to increase very worryingly, to double by 2030 (Dorsey 2007) and even to triple
parkinsonshereandnow
in
Cure Parkinson's
2 years ago
Cerrelle constant bleeding
I was given the progesterone only pill because I can’t take the combination pill as I have aurora migraines and it increases the risk of stroke. Well I have been bleeding constantly for two weeks. I’ve been on it for 5 weeks. I can handle the annoyance of a constant period but not the pain and discomfort
I was given the progesterone only pill because I can’t take the combination pill as I have aurora migraines and it increases the risk of stroke. Well I have been bleeding constantly for two weeks. I’ve been on it for 5 weeks. I can handle the annoyance of a constant period but not the pain and discomfort
ZebraZone
in
Endometriosis UK
2 years ago
Please help. Where do I go next?
I had my first gynaecology appointment this morning and have come away feeling like I haven’t been listened to and my symptoms are not real. I am considering my next steps and whether to go back to my GP. I had been waiting 1.5 years for this appointment and feel very upset that I may now not get any
I had my first gynaecology appointment this morning and have come away feeling like I haven’t been listened to and my symptoms are not real. I am considering my next steps and whether to go back to my GP. I had been waiting 1.5 years for this appointment and feel very upset that I may now not get any
sweetpea2288
in
Endometriosis UK
2 years ago
Alternative to Alendronic Acid
Hi, I’m new to this and wonder if anyone can give me any advice on what I should be taking, as I’m really confused. I am taking Anastrozole after having breast cancer, I then had a bone density scan and was told I had Osteopenia. I am 67 yrs old AP Spine(L1-L4) T-score. -1.4. Z -score 0.4 Femoral
Hi, I’m new to this and wonder if anyone can give me any advice on what I should be taking, as I’m really confused. I am taking Anastrozole after having breast cancer, I then had a bone density scan and was told I had Osteopenia. I am 67 yrs old AP Spine(L1-L4) T-score. -1.4. Z -score 0.4 Femoral
Lucy1578
in
Bone Health and Osteoporosis UK
2 years ago
How long should I take Alendronate
Ive been on prednisone almost 3 years and am currently at 4mg. How long do I need to take Alendronate? I understand that its not good long term.
Ive been on prednisone almost 3 years and am currently at 4mg. How long do I need to take Alendronate? I understand that its not good long term.
Paperroses
in
PMRGCAuk
2 years ago
Treatment for Osteoporosis
Is anyone taking Teriperatide for osteoporosis of the spine? Are you living in the UK? How many fractures do you have? I have refused Alendronic acid because of side effects - Osteo necrosis of the jaw, principally. Phyllis Wilson
Is anyone taking Teriperatide for osteoporosis of the spine? Are you living in the UK? How many fractures do you have? I have refused Alendronic acid because of side effects - Osteo necrosis of the jaw, principally. Phyllis Wilson
Pheewills
in
Bone Health and Osteoporosis UK
2 years ago
Antabuse (disulfiram) Anyone using this for Macular degeneration?
Has anyone be using Antabuse for AMD? What country and hospital? Have you found improment in your vision? Any other comments? best regards de-luke The Full Scientific Paper Can Be Found Here- https://www.science.org/doi/10.1126/sciadv.abm4643 Summary- Rod and cone photoreceptors degenerate in retinitis
Has anyone be using Antabuse for AMD? What country and hospital? Have you found improment in your vision? Any other comments? best regards de-luke The Full Scientific Paper Can Be Found Here- https://www.science.org/doi/10.1126/sciadv.abm4643 Summary- Rod and cone photoreceptors degenerate in retinitis
de-luke
in
Macular Society
2 years ago
Billing for Infusions
Does anyone know how the price of Zoledronic Acid is affected by whether it is given in a rheumatology practice's infusion center versus picked up by the patient at a pharmacy and given at a doctor's office? My rheumatologist says I may have to pick up infusion medication if I need to take it. She is
Does anyone know how the price of Zoledronic Acid is affected by whether it is given in a rheumatology practice's infusion center versus picked up by the patient at a pharmacy and given at a doctor's office? My rheumatologist says I may have to pick up infusion medication if I need to take it. She is
Lynnel17
in
Osteoporosis Support
2 years ago
Bisphosphonate success? My update!
Greetings to all! I can never begin to thank the special few ladies on this site enough who replied to my first note back in the early summer of 2021 and encouraged me with their positive stories and shared fears when I was absolutely terrified to make the decision to start alendronate. Petpal, Bogart0416
Greetings to all! I can never begin to thank the special few ladies on this site enough who replied to my first note back in the early summer of 2021 and encouraged me with their positive stories and shared fears when I was absolutely terrified to make the decision to start alendronate. Petpal, Bogart0416
Loveballet
in
Osteoporosis Support
2 years ago
Big Brother goes to Spain
Good morning from a very rainy Espana ( bloody typical ), just an update to where I am with a couple of concerns. Thought id list meds then people can get a overalls view of my whinging. 40mg Preds to start with followed by 40mg Astorvastin, 150mg Dadigatran, 2.5mg ramipril, 2.5mg Bisoprolol, 75mg Clopigrogrel
Good morning from a very rainy Espana ( bloody typical ), just an update to where I am with a couple of concerns. Thought id list meds then people can get a overalls view of my whinging. 40mg Preds to start with followed by 40mg Astorvastin, 150mg Dadigatran, 2.5mg ramipril, 2.5mg Bisoprolol, 75mg Clopigrogrel
Burnley1959
in
PMRGCAuk
2 years ago
Additional meds from my GP?
Hi Everyone, First to say I am pleased to have just about survived the first Mothering Sunday since my wife Sue's death. Not only the Mum of our lovely 3 kids, but she 'mothered me' too, and I miss it - (as our youngest kindly commented on my Fbook "You were her biggest challenge Dad!!). Also pleased
Hi Everyone, First to say I am pleased to have just about survived the first Mothering Sunday since my wife Sue's death. Not only the Mum of our lovely 3 kids, but she 'mothered me' too, and I miss it - (as our youngest kindly commented on my Fbook "You were her biggest challenge Dad!!). Also pleased
Hopingsail
in
PMRGCAuk
2 years ago
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