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Experiences with
Alpha-1-antitrypsin
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Ambroxol
Would anyone share if you have participated in a clinical trial using the drug Ambroxol for PD? There have been several clinical trials which have published encouraging resusts, mostly in the UK. I am not formally in a trial but have been duplicating the dosage for about 12 months. My experience is favorable
Would anyone share if you have participated in a clinical trial using the drug Ambroxol for PD? There have been several clinical trials which have published encouraging resusts, mostly in the UK. I am not formally in a trial but have been duplicating the dosage for about 12 months. My experience is favorable
Badmouth
in
Cure Parkinson's
2 years ago
Glycine : said to reduce symptoms and reduce aggregation
https://www.michaeljfox.org/grant/modulation-glycine-treatment-parkinsons-disease Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity
https://www.michaeljfox.org/grant/modulation-glycine-treatment-parkinsons-disease Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity
Little_apple
in
Cure Parkinson's
2 years ago
IBOGA
Iboga, ordered 25 grams today and will start "microdosing" soon. Iboga is legal in Germany. I already had party drug experience two decades ago! :-) . A phase 2 study is to begin. I am currently establishing contact. Excerpt from a letter: In the meantime, iboga is not only interesting for addiction
Iboga, ordered 25 grams today and will start "microdosing" soon. Iboga is legal in Germany. I already had party drug experience two decades ago! :-) . A phase 2 study is to begin. I am currently establishing contact. Excerpt from a letter: In the meantime, iboga is not only interesting for addiction
PDTom
in
Cure Parkinson's
2 years ago
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Big, big trouble Houston
I’m 60 now but a guy so I’m still prone to daft things like buying Microsoft Flight Simulator. I flew a 747 the other day and blimey did it let me know when I tried a questionable manoeuvre. Red lights, Commercial Airliner Crash Warning sirens etc. Well it’s sort of a metaphor for me currently. Some
I’m 60 now but a guy so I’m still prone to daft things like buying Microsoft Flight Simulator. I flew a 747 the other day and blimey did it let me know when I tried a questionable manoeuvre. Red lights, Commercial Airliner Crash Warning sirens etc. Well it’s sort of a metaphor for me currently. Some
jeeves19
in
Cure Parkinson's
2 years ago
Thybon Henning doesn’t contain acacia?!
Sharing for info but also a question around changes to formulation. I’ve recently had my T3 increased which meant moving to Thybon Henning 20s. Since I’m allergic to acacia, I set about trying to find out if it contained it. I spoke to 2 pharmacies (SmartWay and Roseseway Labs) as well as doing my
Sharing for info but also a question around changes to formulation. I’ve recently had my T3 increased which meant moving to Thybon Henning 20s. Since I’m allergic to acacia, I set about trying to find out if it contained it. I spoke to 2 pharmacies (SmartWay and Roseseway Labs) as well as doing my
hjh88
in
Thyroid UK
2 years ago
A question about ashwagandha?
I was looking up this herb for interactions on the pharmacuetical database I subscribe to and read the following. I am concerned about any herb that could suppress dopamine, does the statement below mean that dopamine is also reduced which is not good effect for PD? I know many folks with and without
I was looking up this herb for interactions on the pharmacuetical database I subscribe to and read the following. I am concerned about any herb that could suppress dopamine, does the statement below mean that dopamine is also reduced which is not good effect for PD? I know many folks with and without
Sydney75
in
Cure Parkinson's
2 years ago
Lung condition that affects other parts of the body.
Does anyone know anything about
Alpha
-
1
antitrypsin
deficiency?
Does anyone know anything about
Alpha
-
1
antitrypsin
deficiency?
sunrise2801
in
Lung Conditions Community Forum
3 years ago
Low Glutamate Diet
What Is Glutamate? Glutamate is an amino acid that is the most abundant neurotransmitter in the brain. It regulates the receptors of other important neurotransmitters such as: Serotonin Dopamine Norepinephrine Acetylcholine https://epidemicanswers.org/getting-started/diet-basics/low-glutamate-diet
What Is Glutamate? Glutamate is an amino acid that is the most abundant neurotransmitter in the brain. It regulates the receptors of other important neurotransmitters such as: Serotonin Dopamine Norepinephrine Acetylcholine https://epidemicanswers.org/getting-started/diet-basics/low-glutamate-diet
Kia17
in
Cure Parkinson's
2 years ago
Nuchido Laboratories claims a HUGE increase in NAD+
I've been looking at all of the many, many approaches that have been tried in order to increase NAD+. Niaicin, Niacinamide, NR, NMN are a few. The reasons why NAD+ is important are too numerous to list. If you need just one reason, NAD+ is how the energy we bring in (food) becomes energy that our cells
I've been looking at all of the many, many approaches that have been tried in order to increase NAD+. Niaicin, Niacinamide, NR, NMN are a few. The reasons why NAD+ is important are too numerous to list. If you need just one reason, NAD+ is how the energy we bring in (food) becomes energy that our cells
JAS9
in
Cure Parkinson's
2 years ago
PwP, Glaucoma and Citicoline
Previously I posted about the usefulness of Citicoline for memory issues here: https://healthunlocked.com/cure-parkinsons/posts/146670603/part-2-reversing-memory-deficits-and-senior-moments-in-a-78-year-old Here is a review that gives a good idea of the benefits of citicoline in PwP: https://www.researchgate.net
Previously I posted about the usefulness of Citicoline for memory issues here: https://healthunlocked.com/cure-parkinsons/posts/146670603/part-2-reversing-memory-deficits-and-senior-moments-in-a-78-year-old Here is a review that gives a good idea of the benefits of citicoline in PwP: https://www.researchgate.net
chartist
in
Cure Parkinson's
2 years ago
Recent alpha 1 antitrypsin deficiency diagnosed
My Dad told me to get tested and I did and I have tested + for
alpha
1
antitrypsin
deficiency. My GP will not do any follow up appointments as they say I am symptomatic and there for nothing else can be done. This leaves me feeling very vulnerable and uniformed.
My Dad told me to get tested and I did and I have tested + for
alpha
1
antitrypsin
deficiency. My GP will not do any follow up appointments as they say I am symptomatic and there for nothing else can be done. This leaves me feeling very vulnerable and uniformed.
PBID
in
Lung Conditions Community Forum
3 years ago
10 Foods High in Glutamate and Why You Should Avoid Them!
Glutamate is an amino acid that is produced in the body and also occurs naturally in many foods. Monosodium glutamate (MSG) is the sodium salt of glutamic acid and is a common food additive. MSG is made from fermented starch or sugar and is used to enhance the flavor of savory sauces, salad dressings
Glutamate is an amino acid that is produced in the body and also occurs naturally in many foods. Monosodium glutamate (MSG) is the sodium salt of glutamic acid and is a common food additive. MSG is made from fermented starch or sugar and is used to enhance the flavor of savory sauces, salad dressings
Kia17
in
Cure Parkinson's
3 years ago
ScienceofParkinsons: The road ahead: 2022
https://scienceofparkinsons.com/2022/01/20/road2022/ Top 5 #Parkinsons clinical trial results we will be looking out for in 2022: * Phase II Lixisenatide study results * Phase II Liraglutide study results * Phase II PT320 study results (Lots of GLP-1R data) * Phase II UDCA "UP study" results * Phase
https://scienceofparkinsons.com/2022/01/20/road2022/ Top 5 #Parkinsons clinical trial results we will be looking out for in 2022: * Phase II Lixisenatide study results * Phase II Liraglutide study results * Phase II PT320 study results (Lots of GLP-1R data) * Phase II UDCA "UP study" results * Phase
Hidden
in
Cure Parkinson's
3 years ago
New form of gene editing efficient for treatment of Alpha-1 antitrypsin deficiency, liver and lung disease
New research results show that a new form of gene editing is efficient in correcting a mutation in patient cells with the monogenic disease
Alpha
-
1
antitrypsin
deficiency (AATD), a common inherited disease that affects the liver and the lungs.
New research results show that a new form of gene editing is efficient in correcting a mutation in patient cells with the monogenic disease
Alpha
-
1
antitrypsin
deficiency (AATD), a common inherited disease that affects the liver and the lungs.
2greys
in
Lung Conditions Community Forum
3 years ago
Stem cell-based implants successfully secrete insulin in patients with type 1 diabetes...Big Hope...
Interim results from a multicenter clinical trial demonstrate insulin secretion from engrafted cells in patients with type 1 diabetes. The safety, tolerability, and efficacy of the implants, which consisted of pancreatic endoderm cells derived from human pluripotent stem cells (PSCs), were tested
Interim results from a multicenter clinical trial demonstrate insulin secretion from engrafted cells in patients with type 1 diabetes. The safety, tolerability, and efficacy of the implants, which consisted of pancreatic endoderm cells derived from human pluripotent stem cells (PSCs), were tested
DRH-sangli
Star
in
Diabetes India
3 years ago
Opinions on Hemp creams.
Hello everyone, I've recently decided to purchase some compression gloves for my hands and this cream called Hemp Active cream by 5kind popped up on my screen. It has a lot of good reviews but they also have a stronger version. I'm posting this because I've used Voltarol in the past and it doesn't really
Hello everyone, I've recently decided to purchase some compression gloves for my hands and this cream called Hemp Active cream by 5kind popped up on my screen. It has a lot of good reviews but they also have a stronger version. I'm posting this because I've used Voltarol in the past and it doesn't really
Bunnzillah
in
LUPUS UK
3 years ago
New in Type 1 Diabetes "Monogenic Diabetes"
In today's Daily Mail online, you can read about how " Monogenic Diabetes do produce some insulin. " https://www.dailymail.co.uk/health/article-10171247/Type-1-diabetes-sufferers-ditch-insulin-turns-different-hidden-type.html
In today's Daily Mail online, you can read about how " Monogenic Diabetes do produce some insulin. " https://www.dailymail.co.uk/health/article-10171247/Type-1-diabetes-sufferers-ditch-insulin-turns-different-hidden-type.html
sandybrown
in
Diabetes India
3 years ago
Type 1 diabetes Phase 1 trial of the dietary supplement HAMSAB (high-amylose maize resistant starch modified with acetate and butyrate)
Yes, I know it's targeting T1D, but I'm wondering if they would need to change very much if they were to run a similar trial for PD? "Changes in gut microbiota composition, function, and immune profile following six weeks of HAMSAB supplementation were associated with increased SCFAs in stools and plasma
Yes, I know it's targeting T1D, but I'm wondering if they would need to change very much if they were to run a similar trial for PD? "Changes in gut microbiota composition, function, and immune profile following six weeks of HAMSAB supplementation were associated with increased SCFAs in stools and plasma
jeffreyn
in
Cure Parkinson's
3 years ago
Palpitations taking moviprep
Taking moviprep for a colonoscopy tomorrow and having palpitations, has anyone experienced this and did they stop?
Taking moviprep for a colonoscopy tomorrow and having palpitations, has anyone experienced this and did they stop?
Oak321
in
Oesophageal & Gastric Cancer
3 years ago
Labs Trending in the Right Way: Eating Right & Being Mindful
Greetings, fellow travelers: Received a few simple test results back today as a check in. I'm a Type 2 diabetic, with NASH (F2, S3 as diagnosed in November 2020). I also carry a mutant gene for Alpha-1 Anti-Trypsin Disorder, which complicates liver function through binding proteins. Total Cholesterol
Greetings, fellow travelers: Received a few simple test results back today as a check in. I'm a Type 2 diabetic, with NASH (F2, S3 as diagnosed in November 2020). I also carry a mutant gene for Alpha-1 Anti-Trypsin Disorder, which complicates liver function through binding proteins. Total Cholesterol
Gratefulhog
in
Living with Fatty Liver and NASH
3 years ago
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