scienceofparkinsons.com/202...
Top 5 #Parkinsons clinical trial results we will be looking out for in 2022:
* Phase II Lixisenatide study results
* Phase II Liraglutide study results
* Phase II PT320 study results
(Lots of GLP-1R data)
* Phase II UDCA "UP study" results
* Phase II Deferiprone study results
I don't know whether to be excited or depressed about the huge number of trials and studies which are being undertaken. On one hand, it's encouraging to know PD is being attacked from dozens, if not hundreds of angles. On the other hand, the sheer number of approaches suggests that we're a long way from any kind of "cure" as Stott defines it. It would be nice if there was one universally known cause and one exact target. Unless or until that happens, I guess we can hope for a random bullseye using the current shotgun approach.
Good stuff. This is the part that I focus on:
COMPONENT #1: A disease halting mechanism
The direct approach
The direct approach: Alpha synuclein
Passive immunotherapy approaches for alpha synuclein
Active (vaccine) immunotherapy approaches for alpha synuclein
Small molecule approaches targeting alpha synuclein
The direct approach: LRRK2
The direct approach: GBA
The direct approach: Mitochondria
The direct approach: Additional
The indirect approach
The indirect approach: Autophagy
The indirect approach: Inflammation
The indirect approach: Gastrointestinal system
The indirect approach: Iron chelation
I was a patient in the Alpha synuclein trial in Orlando. Alpha synuclein works very well. However, the dosage I needed to pull myself out of the offtime was so high the film started to irritate my tongue and mouth lining.
If J&J can get the Wuhan virus to swap its genetic code with a spike code to kill itself, we aren’t far off. It’s a matter of time most of us haven’t got and\or can’t get back.
If Congress is having trouble deciding between aid to Iran and PD they should spend a week with me. I got a buddy who can fly that plane load of cash to the Mayo clinic front door…
Regarding the Nicotinamide Riboside (a form of Vitamin B3) study in Norway here is the HU link I found
Does nobody else here wish he would produce executive summaries?
"Plenty going on. Nothing imminent. Check back in a year (or 5)"
He fooled you by putting it at the end:
Interesting: "ENT-01 is a synthetic version of squalamine, a molecule originally discovered in the liver and gall bladder of the dogfish shark."
I think there is a cure for everything in nature, we just have to discover it.
Glutathione discussion
