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Androgen deprivation therapy (ADT)
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Bipolar Androgen Therapy Followed by Androgen Receptor Inhibition as Sequential Therapy for Prostate Cancer
Importantly, BAT should always be given in conjunction with ongoing
ADT
.
BAT is not to be used in patients with castration-sensitive disease outside of a clinical trial.
Importantly, BAT should always be given in conjunction with ongoing
ADT
.
BAT is not to be used in patients with castration-sensitive disease outside of a clinical trial.
pjoshea13
in
Fight Prostate Cancer
1 year ago
what to expect
Is the loss of energy and weakness due to the chemotherapy or to the
ADT
? How long will it take to begin to recover from the side effects of chemotherapy? Am I going to remain at this level of energy or will I begin to get that back? When make that happen?
Is the loss of energy and weakness due to the chemotherapy or to the
ADT
? How long will it take to begin to recover from the side effects of chemotherapy? Am I going to remain at this level of energy or will I begin to get that back? When make that happen?
DoubleBlind
in
Advanced Prostate Cancer
1 year ago
Cause of steady increase in Alt (liver) score
My husband is on
ADT
3 monthly (10.8mg) Zoladex and due to have 6th and final Doxetaxal infusion next Thursday but his Alt score is now 114. He also takes Prednisolone and Omeprazole and he’s on a clinical trial too so is taking Metformin.
My husband is on
ADT
3 monthly (10.8mg) Zoladex and due to have 6th and final Doxetaxal infusion next Thursday but his Alt score is now 114. He also takes Prednisolone and Omeprazole and he’s on a clinical trial too so is taking Metformin.
RunningViv
in
Advanced Prostate Cancer
1 year ago
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Rethinking Radiation to spine
I had the risks explained to me and my concern is that maybe I should let the
ADT
and 2nd gen do its work and hopefully hold the growth down for as long as I remain hormone sensitive, whatever that might be.
I had the risks explained to me and my concern is that maybe I should let the
ADT
and 2nd gen do its work and hopefully hold the growth down for as long as I remain hormone sensitive, whatever that might be.
treedown
in
Advanced Prostate Cancer
1 year ago
Cyproterone and Blood Pressure
I am currently on LHRH hormone therapy in preparation for radiotherapy followed by HDR brachytherapy for my locally advanced PCa, T3a Gleason 8, no visible mets fortunately. I have been suffering from quite unpleasant hot flushes which have shown no signs of going away. I discussed this with my consultant
I am currently on LHRH hormone therapy in preparation for radiotherapy followed by HDR brachytherapy for my locally advanced PCa, T3a Gleason 8, no visible mets fortunately. I have been suffering from quite unpleasant hot flushes which have shown no signs of going away. I discussed this with my consultant
tunybgur
in
Advanced Prostate Cancer
7 months ago
my life is miserable life due to hormone treatment (eligard) want to quit asap . questions to ask ? /experiences ?
Im a very active 61 - had zero symptoms - no peeing in the night etc and 15 PSA was only flagged while doing pre op for a hip replacement in January. Next PSA was 17 in March so in for biopsy - 8 positive biopsy samples of 48 taken but only one of concern with Gleason of 8. PET scan indicated borderline
Im a very active 61 - had zero symptoms - no peeing in the night etc and 15 PSA was only flagged while doing pre op for a hip replacement in January. Next PSA was 17 in March so in for biopsy - 8 positive biopsy samples of 48 taken but only one of concern with Gleason of 8. PET scan indicated borderline
moon1878
in
Prostate Cancer Network
7 months ago
SBRT - 1 year after
Overall, )beyond the testing, 2months of
ADT
and gold marker implants), not a terrible experience. Now, a year later, i would like to report: THE GOOD. my PSA is down to .3 and my T cell count is back to 600. my energy is fine and i am able to live my life to 95% of its normal capacity.
Overall, )beyond the testing, 2months of
ADT
and gold marker implants), not a terrible experience. Now, a year later, i would like to report: THE GOOD. my PSA is down to .3 and my T cell count is back to 600. my energy is fine and i am able to live my life to 95% of its normal capacity.
chrisNYC
in
Prostate Cancer Network
1 year ago
Clinical trial: keep an eye on this
First results should be available by the first months of 2024. Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive
First results should be available by the first months of 2024. Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation Enhancing Medication (M3814) Versus Radium-223 Dichloride Plus M3814 Plus Avelumab (a Type of Immunotherapy) for Advanced Prostate Cancer Not Responsive
Maxone73
in
Advanced Prostate Cancer
7 months ago
NCCN Blasphemy?
But now if the same person has a single core of GGG2 disease, they go all the way to unfavorable disease and need
ADT
if they opt for RT (and are no longer a Brachy only candidate)? Give me a break. I personally don’t count the GGG1 cores and neither do our urologists. It wouldn’t make sense.
But now if the same person has a single core of GGG2 disease, they go all the way to unfavorable disease and need
ADT
if they opt for RT (and are no longer a Brachy only candidate)? Give me a break. I personally don’t count the GGG1 cores and neither do our urologists. It wouldn’t make sense.
TFU589
in
Prostate Cancer Network
1 year ago
HT weight gain
My husband will be starting hormone therapy <HT> prior to radiation treatment <RT>.The weight gain associated with HT is a concern. Any suggestions? Any medication available to assist with weight loss during HT? Inquisitive One
My husband will be starting hormone therapy <HT> prior to radiation treatment <RT>.The weight gain associated with HT is a concern. Any suggestions? Any medication available to assist with weight loss during HT? Inquisitive One
Inquisitive_one
in
Advanced Prostate Cancer
7 months ago
Bone Problems
4 years on
ADT
and Abiraterone. Had spine fracture and now have osteopenia due to medication. has anyone else suffered bone issues with this medication.
4 years on
ADT
and Abiraterone. Had spine fracture and now have osteopenia due to medication. has anyone else suffered bone issues with this medication.
Lion321
in
Advanced Prostate Cancer
1 year ago
3,100 PSA!
After two (2) Pluvicto infusions, my PSA went from 2,000. to 3,000. I haven't had any hormone treatments for approximately six months, and was subsequently told my Dr. should have kept me on Standard of Care (SoC) right through Pluvicto. Q1: Anyone out there know of any options open to me in this
After two (2) Pluvicto infusions, my PSA went from 2,000. to 3,000. I haven't had any hormone treatments for approximately six months, and was subsequently told my Dr. should have kept me on Standard of Care (SoC) right through Pluvicto. Q1: Anyone out there know of any options open to me in this
fsiefert
in
Advanced Prostate Cancer
7 months ago
Lump on buttocks due to FULVESTRANT injection
My mom is diagnosed with stage 4 breast cancer .. currently she is on her hormonal therapy ..FULVESTRANT injection are injected ....the injections are injected on buttocks ..due to this there is lump on her buttocks, but its not going away , even after all the cold , hot compress..so what should i do
My mom is diagnosed with stage 4 breast cancer .. currently she is on her hormonal therapy ..FULVESTRANT injection are injected ....the injections are injected on buttocks ..due to this there is lump on her buttocks, but its not going away , even after all the cold , hot compress..so what should i do
Hidden
in
Breast Cancer India
7 months ago
How fast should your PSA drop after the first ADT treatment.
My husband has stage 4. It is in his lungs, ribs, shoulder and spine. Plus a lot of the lymph nodes. No pain except when he broke his ribs just lying on his stomach. That is healing without the palliative radiation. How fast should his PSA drop. How will we know if this is working. I know this treatment
My husband has stage 4. It is in his lungs, ribs, shoulder and spine. Plus a lot of the lymph nodes. No pain except when he broke his ribs just lying on his stomach. That is healing without the palliative radiation. How fast should his PSA drop. How will we know if this is working. I know this treatment
Bo1948
in
Advanced Prostate Cancer
1 year ago
6 years now and PSA <0.01 is it time for a vacation?
Hello, after chemotherapy, STRT of the prostate, I have been taking Eligard hormone therapy for 6 years now and PSA <0.01 is it time for a vacation?
Hello, after chemotherapy, STRT of the prostate, I have been taking Eligard hormone therapy for 6 years now and PSA <0.01 is it time for a vacation?
Vasili
in
Advanced Prostate Cancer
7 months ago
Stage 4
Had 18 Chemo treatments, 20 radiation, on
ADT
from Start, PSA not readable after 22 months. Dr advises to stop
ADT
, to improve lifestyle. Not sure if this will increase risk of return sooner?
Had 18 Chemo treatments, 20 radiation, on
ADT
from Start, PSA not readable after 22 months. Dr advises to stop
ADT
, to improve lifestyle. Not sure if this will increase risk of return sooner?
Natvega
in
Advanced Prostate Cancer
2 years ago
Cardio performance abrupt decline
Could this be a reaction to
ADT
?
Could this be a reaction to
ADT
?
SViking
in
Advanced Prostate Cancer
1 year ago
Why do my feet and ankles stay swollen while on ADT therapy
Why do my feet and ankles stay swollen while on
ADT
therapy
Why do my feet and ankles stay swollen while on
ADT
therapy
barryium
in
Advanced Prostate Cancer
1 year ago
Dual Action Hormone Therapy Targeting Two Parts of Androgen Receptor for mCRPC
Phase I/II trial of masofaniten combined with enzalutamide, a novel hormonal therapy for mCRPC. Masofaniten, a first-in-class N-terminal ligand antagonist for the androgen receptor, shows promise in overcoming resistance to current hormonal therapies. Hopefully a new weapon for us!
Phase I/II trial of masofaniten combined with enzalutamide, a novel hormonal therapy for mCRPC. Masofaniten, a first-in-class N-terminal ligand antagonist for the androgen receptor, shows promise in overcoming resistance to current hormonal therapies. Hopefully a new weapon for us!
Maxone73
in
Advanced Prostate Cancer
8 months ago
I have questions about Tamoxifen, aka Hormonal Therapy
Hello all, & blessed wishes during the Holiday Season. 🎄 I must admit I haven't been on here for a while, but I hope someone can give me some answers. I was diagnosed with Clear Cell Ovarian Cancer stage 4 in 2021. I have had 6 rounds of Chemo, & a total hysterectomy. I've been doing Avastin since
Hello all, & blessed wishes during the Holiday Season. 🎄 I must admit I haven't been on here for a while, but I hope someone can give me some answers. I was diagnosed with Clear Cell Ovarian Cancer stage 4 in 2021. I have had 6 rounds of Chemo, & a total hysterectomy. I've been doing Avastin since
gta03
in
SHARE Ovarian Cancer Support
8 months ago
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