Currently on Orgovyx for the last 18 months with very little side effects due to wrestling, lifting weights and hiking. Then suddenly four days ago, only a block from the beginning of my daily 2.5 mile hike my energy unexpectedly ran out. I pushed forward another block assuming I could shake off whatever hit me but the fatigue went from zero to ten in the next minute.
Reluctantly turning around and heading home turned to staggering so bad someone stopped and asked if I was okay and if I needed the paramedics. I declined that but could not walk any further so I accepted a ride home. My speech was slow for a few hours but no other signs of a stroke like droopy face etc. Normally my energy level is high in the mornings with some fatigue mid-afternoons. But nothing like this has ever happened.
My blood pressure is normally low but this time it dropped to 107/76 with a pulse of 48. Still feeling extremely lightheaded and still lacking sufficient energy for even light training. I got in quickly to see the cardiologist who ran an EKG with nothing odd--same with my neurologist.
All day today the slightest exertion led to a buzzing fatigue within minutes. Could this be a reaction to ADT?
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we actually did all those tests a few months ago, even the nuclear stress test. The result was that I have calcified blood vessels, but my interior walls are not clogged. However, my calcium score was 875. When reading up on that, I just covered that my odds of having a cardiovascular event were 90% in the next few years. My cardiologist recommended Lipitor, which I will start soon. My main concern at this point is if I’m going to have a heart attack while training.
I am on Orgovyx and have an active program of weight training and cycling. My Blood pressure tends to be low but has never been a problem. I have recently been having episodes of orthostatic hypotension (low blood pressure when standing up from sitting or lying down). My BP is also noted to be lower when taken with medical visits. Could it be related to Orgovyx therapy? I would like to hear from others.
I'd like to know what others think, but I wouldn't consider a BP of 107/76 as low, I wish I had that. And your pulse rate of 48 surely that is a measure of your excellent fitness level? Am I interpreting those stats correctly?
A pulse of 48 is considered bradycardia unless one has been a marathon runner for a long time. I got bradycardia after starting the loading dose of Orgovyx. I stopped Orgovyx and restarted a few days later without the loading dose. No bradycardia then but heart rate remains in the 50s. (I do a lot of cardio work on the elliptical so that may help keep my heart rate lower-not sure.)
When I was experiencing AFib, "breakthrough" episodes such as you describe were common. They would come on quickly while I was exercising, particularly when riding my bike for longer distances. They would go away, but...we couldn't control it with various medications, finally did the ablation, problem solved.
ablation is where they go in through the arm or groin and run a catheter up and into the heart after mapping the electrical function of the heart muscle they cryogenically "burn" out the nerves causing the a-fib. The scar tissue prevents further nerve transmission. As long as the nerves don't "heal" and reconnect normal sinus rhythm is maintained
You do not know that it was an Afib episode or other arrhythmia. The monitor is a good idea.
You do have a high risk for CVD event. The high EBT calcium indicates that. Coronary plaques can be stabilized over time with maximal tolerated doses of statin like Lipitor. And / or the even more effective PCSK9 inhibitors which you should discuss with your cardiologist. Your LDL cholesterol should be kept below 70 on these medications. ApoB level is even better indicator and should be kept below 60, 30-40 is even better in very high risk individuals. If you don’t have stomach issues than consider and discuss low dose enteric aspirin.
I had EBT calcium score of over 900 and also plaques in my carotids. That was 30 years ago. Have been on Lipitor 80mg ever since and no problems and no exercise limitations. And as a lifelong runner (well now more of a walker/hiker) my resting pulse is 48-50. No wrestling for me though! Paul
I hear many solutions to high cholesterol. What's the best way to lower it without meds?
hmmmm I had a normal EKG and stress test once and a month later felt like crap. Hit a $5K jackpot, no excitement. Did a heart cath and uncovered an aortic aneurism with a blood clot attached. Put in ICU and 12 hours later, a double bypass.
Not a heart catheter. Cardiac catheterization, commonly called a heart cath, is a procedure in which a thin, flexible tube (catheter) is guided through a blood vessel from the groin to the heart to diagnose or treat certain heart conditions, such as clogged arteries or irregular heartbeats. During cardiac catheterization, doctors can do different heart tests, deliver treatments, or remove a piece of heart tissue for examination. Some heart disease treatments — such as coronary angioplasty and coronary stenting — are done using cardiac catheterization.
Done by a Cardiologist using a Fluroscope. I watched mine on a monitor. There are 7 or 8 types of angiograms. It’s in the same family. Some are done by Radiologists.
I had an Aortic Aneurism with a blood clot fleppung like a plumb bob, opening and closing.
Also his book “eat rich live long” is good quality big book, well written, color graphs, scientific references. Just a perfect book for you to read asap.
I AM NOT A DOCTOR so take this with a grain of salt and do not use my reply to mean anything actionable on your part -
In simpler terms, the report states that there is some mild loss of brain volume and changes in the white matter due to reduced blood flow. However, there is no evidence of recent stroke or bleeding in the brain. The ventricles (fluid-filled spaces in the brain) are normal, and there are no signs of pressure on the brain. The blood vessels and spaces outside the brain are also normal. The report mentions some minor issues with the sinuses, but these are not considered urgent or serious. Overall, there are no major concerns, but there are some long-standing issues that require further monitoring.
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PSA DECLINING WHILE IT WAS RISING
Historical testosterone decline
PSA still declining 
Recent Cardio Experience
