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Experiences with
Androgen deprivation therapy (ADT)
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PSA rising on Triplet Therapy after <18m
His quality of life has been good while on
ADT
. I am trying to get a better sense of what QoL will be going forward, assuming he will require different treatments, either in addition to or alongside
ADT
. Besides the cancer, his health is very good.
His quality of life has been good while on
ADT
. I am trying to get a better sense of what QoL will be going forward, assuming he will require different treatments, either in addition to or alongside
ADT
. Besides the cancer, his health is very good.
nyc_son
in
Advanced Prostate Cancer
6 months ago
Recovery of Testosterone
We all have heard about how long it takes to recover testosterone after you stop
ADT
. You probably also heard how age affects recovery time. The older you are the longer it takes and the T may never recover. The type of
ADT
you take can also affect recovery time - shot versus pill.
We all have heard about how long it takes to recover testosterone after you stop
ADT
. You probably also heard how age affects recovery time. The older you are the longer it takes and the T may never recover. The type of
ADT
you take can also affect recovery time - shot versus pill.
Mgtd
in
Prostate Cancer Network
7 months ago
TRT Causing Breast Enlargement
Am considering it because two years after
ADT
. (18 months Lupron and Bicalutamide) my T level is 66, PSA .28.
Am considering it because two years after
ADT
. (18 months Lupron and Bicalutamide) my T level is 66, PSA .28.
Jack54
in
Advanced Prostate Cancer
9 months ago
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Low-T is associated with worse Prostate Cancer Specific Mortality probability after 6 months of ADT: Part II
The cohort is: Unfavorable Risk after TR and 6 months of
ADT
. These plots show that the probability of dying from prostate cancer (after PSA failure) is significantly worse for men with Low-T.
The cohort is: Unfavorable Risk after TR and 6 months of
ADT
. These plots show that the probability of dying from prostate cancer (after PSA failure) is significantly worse for men with Low-T.
janebob99
in
Prostate Cancer Network
5 months ago
PSA relapse rate vs testosterone nadir - 3
This plot shows the PSA relapse rate after RT and
ADT
, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL).
This plot shows the PSA relapse rate after RT and
ADT
, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL).
janebob99
in
Advanced Prostate Cancer
6 months ago
PSA Survival vs Testosterone Nadir - 2
This plot shows the Biochemical Relapse Free Survival after RT and
ADT
, after 10 years , for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL).
This plot shows the Biochemical Relapse Free Survival after RT and
ADT
, after 10 years , for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL).
janebob99
in
Advanced Prostate Cancer
6 months ago
Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron
ADT
to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment.
Here's some charts comparing Lupron
ADT
to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment.
janebob99
in
Prostate Cancer Network
6 months ago
Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron
ADT
to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment.
Here's some charts comparing Lupron
ADT
to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment.
janebob99
in
Advanced Prostate Cancer
6 months ago
At what point for scan ?
Gleason score 9 PSA- 4.13 ( May ) Referred to oncologist in July and diagnosed in October of 2023 35 ( Nov 29 ) 2.79 ( after 5 weeks of
ADT
) 0.45 ( after # 1 chemo ) 0.27 ( after # 2 chemo ) 0.14 ( after # 3 chemo )
Gleason score 9 PSA- 4.13 ( May ) Referred to oncologist in July and diagnosed in October of 2023 35 ( Nov 29 ) 2.79 ( after 5 weeks of
ADT
) 0.45 ( after # 1 chemo ) 0.27 ( after # 2 chemo ) 0.14 ( after # 3 chemo )
positive-thinking
in
Advanced Prostate Cancer
5 months ago
PSA still undectable
it’s been 4 months now since I didn’t have my
ADT
injection ( so 7 months since the last one). Continuing on Apalutamide as a monotherapy atm. Pleased to have experienced Christmas and a 3 week hol in Barbados with no bad news as Decembers have bed. Dodgy in the past.
it’s been 4 months now since I didn’t have my
ADT
injection ( so 7 months since the last one). Continuing on Apalutamide as a monotherapy atm. Pleased to have experienced Christmas and a 3 week hol in Barbados with no bad news as Decembers have bed. Dodgy in the past.
Brysonal
in
Fight Prostate Cancer
7 months ago
Quite happy with ADT
Almost 83 years old, living presently in Germany, RT and PT not possible,
ADT
during the last 9 months (Lupron quarterly), PSA down to undetectable, quite happy with that.
Almost 83 years old, living presently in Germany, RT and PT not possible,
ADT
during the last 9 months (Lupron quarterly), PSA down to undetectable, quite happy with that.
EBBEFLUT
in
Advanced Prostate Cancer
9 months ago
Five years later
I had an unconventional treatment path, where my oncologist, after chemo and radiation, continued
ADT
( lupron) for two years. After that he moved the injection time up to 4 months( 2x),5 months(2x),and six months(2x).
I had an unconventional treatment path, where my oncologist, after chemo and radiation, continued
ADT
( lupron) for two years. After that he moved the injection time up to 4 months( 2x),5 months(2x),and six months(2x).
ArnieAfrica
in
Advanced Prostate Cancer
2 months ago
Life Expectancy
Initially, he underwent radiation for a few spots on his ribs and immediately began
ADT
/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he had PSA tests every three months, and everything seemed stable.
Initially, he underwent radiation for a few spots on his ribs and immediately began
ADT
/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he had PSA tests every three months, and everything seemed stable.
godhelpus
in
Advanced Prostate Cancer
6 months ago
PSA vs Testosterone plot has large scatter, but still confirms Morgentaler's Saturation Model.
This is an important result for
castrate-resistant
men who want to supplement their T level (for example, from 200 to 1000+ ng/dL) after completing their
ADT
treatment cycle.
This is an important result for
castrate-resistant
men who want to supplement their T level (for example, from 200 to 1000+ ng/dL) after completing their
ADT
treatment cycle.
janebob99
in
Prostate Cancer Network
5 months ago
Can Nubeqa (Darolutamide) be used instead of normal ADT drugs for localized PCa?
It seems that this drug has fewer side effects than the usual
ADT
drugs and from what I can gather does a pretty good job of preventing the growth and spread of PCa. So my question is; Can we use this drug in place of
ADT
when we also use RT to get on top of localised PCa?
It seems that this drug has fewer side effects than the usual
ADT
drugs and from what I can gather does a pretty good job of preventing the growth and spread of PCa. So my question is; Can we use this drug in place of
ADT
when we also use RT to get on top of localised PCa?
Mike58
in
Advanced Prostate Cancer
9 months ago
Eosinophilic Oesophagitis from ADT ?
Following some recent episodes of choking on fluids, I have had an edoscopy plus tissue biopsies which show eosinophilic oesophagitis. This can be simply described as an inflammatory disorder of the oesophagus due to food based proteins or other substances. I have some very long standing food allergies
Following some recent episodes of choking on fluids, I have had an edoscopy plus tissue biopsies which show eosinophilic oesophagitis. This can be simply described as an inflammatory disorder of the oesophagus due to food based proteins or other substances. I have some very long standing food allergies
Leigh2350
in
Advanced Prostate Cancer
2 months ago
ADT + Zytiga holiday???
The nerve pain has gotten worse and my oncologist and neurologist are wondering if
ADT
or Zytiga are too blame. Anyone have experience with these drugs and nerve interaction?
The nerve pain has gotten worse and my oncologist and neurologist are wondering if
ADT
or Zytiga are too blame. Anyone have experience with these drugs and nerve interaction?
VanHalen84
in
Advanced Prostate Cancer
10 months ago
deciding whether to do pluvicto with hemoglobin around 8
ADT
for 7 years, failed zytiga after being on it for 3 years, failed 3 rounds of doxetaxol this past fall. Radiation treatments to pelvis in 2021 and spine, hip in 2023. Had BRCA mutations so tried Lynparza January 24.
ADT
for 7 years, failed zytiga after being on it for 3 years, failed 3 rounds of doxetaxol this past fall. Radiation treatments to pelvis in 2021 and spine, hip in 2023. Had BRCA mutations so tried Lynparza January 24.
LJGD
in
Advanced Prostate Cancer
5 months ago
I got some doubts about the know-how of my oncologist
Yet, my oncologist is very insistent that I go back on
ADT
. She wanted me back on
ADT
even when my PSA was of 0.09. The problem is that I don't want to go on
ADT
unless I really need it as it is quite debilitating for me.
Yet, my oncologist is very insistent that I go back on
ADT
. She wanted me back on
ADT
even when my PSA was of 0.09. The problem is that I don't want to go on
ADT
unless I really need it as it is quite debilitating for me.
Mascouche
in
Advanced Prostate Cancer
10 months ago
Low-T is associated with worse Prostate Cancer Specific Mortality probability after 6 months of ADT: Part III
The cohort is: Unfavorable Risk after RT and 6 months of
ADT
. These plots show that the probability of dying from prostate cancer (after PSA failure) is significantly worse for men with Low-T.
The cohort is: Unfavorable Risk after RT and 6 months of
ADT
. These plots show that the probability of dying from prostate cancer (after PSA failure) is significantly worse for men with Low-T.
janebob99
in
Prostate Cancer Network
5 months ago
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