PSA Survival vs Testosterone Nadir - 2 - Advanced Prostate...

Advanced Prostate Cancer

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PSA Survival vs Testosterone Nadir - 2

janebob99 profile image
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This plot shows the Biochemical Relapse Free Survival after RT and ADT, after 10 years , for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019)

The best outcomes are significantly associated with a lower testosterone nadir ( < 20 ng/dL), and the relationship appears to be roughly linear; heading toward a 100 % survival rate for a testosterone nadir = 0.

This may be well-known to many of you, but it was new to me.

The prior definition of castration being < 50 ng/dL probably needs to redefined to < 20 ng/dL. (I read that the level of 50 ng/dL may be an artifact representing the lowest limit that testosterone could be accurately measured many years ago. That makes sense to me).

Ref: ncbi.nlm.nih.gov/pmc/articl...

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j-o-h-n profile image
j-o-h-n

to janebob, I think we may start charging you by the post.......

Good Luck, Good Health and Good Humor.

j-o-h-n

CAMPSOUPS profile image
CAMPSOUPS in reply to j-o-h-n

Extra charge for posts containing a chart

janebob99 profile image
janebob99 in reply to CAMPSOUPS

Ha ! Too funny!!

Thanks for the laughs.

j-o-h-n profile image
j-o-h-n in reply to CAMPSOUPS

9.7 on my laugh meter....... Thanks...(p.s. only I get 10's)....

Good Luck, Good Health and Good Humor.

j-o-h-n

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