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melatonin
I would not recommend high dose melatonin for us who are on ADT and
abiraterone
. Impairs dexterity and cognitive ability.
I would not recommend high dose melatonin for us who are on ADT and
abiraterone
. Impairs dexterity and cognitive ability.
Nowhereman9
in
Advanced Prostate Cancer
9 months ago
The paradigm has shifted - castrate resistance.
I’ve now added
Abiraterone
to the Lupron. My next checkup is at the end of March to check my PSA and my liver numbers. When I initially started Abi 6 years ago my liver numbers went wonky at first. My MO stopped the Abi for a month and my liver numbers recovered.
I’ve now added
Abiraterone
to the Lupron. My next checkup is at the end of March to check my PSA and my liver numbers. When I initially started Abi 6 years ago my liver numbers went wonky at first. My MO stopped the Abi for a month and my liver numbers recovered.
fireandice123
in
Advanced Prostate Cancer
5 months ago
Stopping abiraterone
I've been on
Abiraterone
+Prednisone for about a year and a half, with a 2 month break around Christmas last year. My Doc says the normal course of
Abiraterone
is about 18 months, and I think that we're kind of dancing around discontinuing the drug, for me.
I've been on
Abiraterone
+Prednisone for about a year and a half, with a 2 month break around Christmas last year. My Doc says the normal course of
Abiraterone
is about 18 months, and I think that we're kind of dancing around discontinuing the drug, for me.
chickgreen
in
Advanced Prostate Cancer
10 months ago
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Full circle with this disease
Castrate resistant 2022 started
Abiraterone
and prednisone this failed after 3 months. Start Xgeva and Xofigo 2023. PSA back at 105 November 2023. Start 10 rounds of Docetaxel and PSA starts dropping again. After first treatment PSA drops to 62 then 17 and then 5.
Castrate resistant 2022 started
Abiraterone
and prednisone this failed after 3 months. Start Xgeva and Xofigo 2023. PSA back at 105 November 2023. Start 10 rounds of Docetaxel and PSA starts dropping again. After first treatment PSA drops to 62 then 17 and then 5.
Islandboy2021
in
Advanced Prostate Cancer
6 months ago
Next Steps
He had a orchiectomy, is on
ABIRATERONE
500MG and has just completed six treatments of Doxetaxel . Had a bad spell with phenomena in December which weakened him. In January he had another spell related to morphine.
He had a orchiectomy, is on
ABIRATERONE
500MG and has just completed six treatments of Doxetaxel . Had a bad spell with phenomena in December which weakened him. In January he had another spell related to morphine.
Sparlingo
in
Advanced Prostate Cancer
5 months ago
Abiraterone Caused High Blood Pressure
I started Lupron 3 month +
Abiraterone
+ Prednisone almost 4 weeks ago. In 4 weeks, my Blood Counts went down (see indicators below). My Blood Pressure is higher than before (90 - 148).
I started Lupron 3 month +
Abiraterone
+ Prednisone almost 4 weeks ago. In 4 weeks, my Blood Counts went down (see indicators below). My Blood Pressure is higher than before (90 - 148).
FightCancer101
in
Advanced Prostate Cancer
8 months ago
Odd statement found in STAMPEDE trial results
But the trial found that
abiraterone
reduced the risk of serious bone problems by a half." https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-hormone-therapy-with-other-treatments-for-prostate-cancer-stampede-trial-results#undefined Hmmmmm
But the trial found that
abiraterone
reduced the risk of serious bone problems by a half." https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-hormone-therapy-with-other-treatments-for-prostate-cancer-stampede-trial-results#undefined Hmmmmm
Hidden
in
Advanced Prostate Cancer
9 months ago
beta sitosterol
Coupling these with Ivermectin, melatonin , Lupron and
abiraterone
. Anyone with any success with these?
Coupling these with Ivermectin, melatonin , Lupron and
abiraterone
. Anyone with any success with these?
Nowhereman9
in
Advanced Prostate Cancer
10 months ago
Lupron Question.
September 2023
Abiraterone
and 5mg of prednisone was added. Psa was 19 in Sept and dropped to 1.26 as of Jan. 11 2024. Since going on Abi when I get a monthly Lupron shot I have trouble sleeping that first night and mild flu like symptoms the next day.
September 2023
Abiraterone
and 5mg of prednisone was added. Psa was 19 in Sept and dropped to 1.26 as of Jan. 11 2024. Since going on Abi when I get a monthly Lupron shot I have trouble sleeping that first night and mild flu like symptoms the next day.
Professorgary
in
Advanced Prostate Cancer
6 months ago
Fallout from PET/CT Scan
This made my cancer castrate resistant and I am on
Abiraterone
1000 mg + Prednisone 5 mg. The PET/CT report also stated severe coronary artery calcification. Yesterday I had CT scan of the heart.
This made my cancer castrate resistant and I am on
Abiraterone
1000 mg + Prednisone 5 mg. The PET/CT report also stated severe coronary artery calcification. Yesterday I had CT scan of the heart.
dac500
in
Advanced Prostate Cancer
7 months ago
phase 2 study for mCRPC
https://www.uclahealth.org/clinical-trials/study-two-dose-levels-vobramitamab-duocarmazine-participants For people previously treated with apalutamide, darolutamide, enzalutamide,
abiraterone
It’s and ADC targeting B7-H3 checkpoint https://clinicaltrials.gov/study/NCT05032040 Targets PD1
https://www.uclahealth.org/clinical-trials/study-two-dose-levels-vobramitamab-duocarmazine-participants For people previously treated with apalutamide, darolutamide, enzalutamide,
abiraterone
It’s and ADC targeting B7-H3 checkpoint https://clinicaltrials.gov/study/NCT05032040 Targets PD1
Maxone73
in
Advanced Prostate Cancer
9 months ago
Order of treatment?
My husband has been on
Abiraterone
for 5 months during which time his PSA has risen,. Before that he had had 6 rounds of Docetaxel which also saw his PSA rise.
My husband has been on
Abiraterone
for 5 months during which time his PSA has risen,. Before that he had had 6 rounds of Docetaxel which also saw his PSA rise.
NLondon43
in
Advanced Prostate Cancer
8 months ago
Making a Case for Intermittent ADT in Metastatic Hormone Sensitive Prostate Cancer
My first treatment used SBRT plus
abiraterone
and Lupron for 22 months, and resulted in a vacation of 22 months for me. Opting for a shorter treatment time, I was treated for 12 months the second time...
My first treatment used SBRT plus
abiraterone
and Lupron for 22 months, and resulted in a vacation of 22 months for me. Opting for a shorter treatment time, I was treated for 12 months the second time...
NPfisherman
in
Fight Prostate Cancer
2 months ago
Arrythmias on Zytiga
Abiraterone
ends march 1, 2024. So I’d be 5 months short.
Abiraterone
ends march 1, 2024. So I’d be 5 months short.
Oceankayaker
in
Advanced Prostate Cancer
10 months ago
Good news for mCRPC (hopefully), phase 2
And here we go: "mCRPC patients who have relapsed or are refractory to androgen receptor signalling inhibitors (ARSIs) such as apalutamide, darolutamide,
abiraterone
and enzalutamide are included in the study." https://www.clinicaltrialsarena.com/news/oncternal-patient-prostate-cancer/
And here we go: "mCRPC patients who have relapsed or are refractory to androgen receptor signalling inhibitors (ARSIs) such as apalutamide, darolutamide,
abiraterone
and enzalutamide are included in the study." https://www.clinicaltrialsarena.com/news/oncternal-patient-prostate-cancer/
Maxone73
in
Advanced Prostate Cancer
9 months ago
My brother has advanced Prostate Cancer
After some genetic tests and so many scans, his M.O. decided to start
Abiraterone
and Prednisone for him 2 month ago. After 1 month his PSA increased but M.O. told him we should wait at least 3 months to make sure. Now 2 months passed and his PSA increased again from 39 to 46.
After some genetic tests and so many scans, his M.O. decided to start
Abiraterone
and Prednisone for him 2 month ago. After 1 month his PSA increased but M.O. told him we should wait at least 3 months to make sure. Now 2 months passed and his PSA increased again from 39 to 46.
rasher1
in
Advanced Prostate Cancer
8 months ago
help - prostate cancer with bone metastasis in bones - patient 70 years old - PERU
As treatment, he was prescribed
ABIRATERONE
and with that his PSA dropped from 22 PSA in August to 9 PSA in November. Now for the pain they told him that he should have radiotherapy for the lumbar area (spine).
As treatment, he was prescribed
ABIRATERONE
and with that his PSA dropped from 22 PSA in August to 9 PSA in November. Now for the pain they told him that he should have radiotherapy for the lumbar area (spine).
DiegoFerruaPE
in
Advanced Prostate Cancer
8 months ago
Phase III Study: Saruparib Combo with New Hormonal Agents in mCSPC +/- HRR Mutations: AUA 2024 EvoPAR-Prostate01 Trial
The safety and efficacy of saruparib plus new hormonal agents for the treatment of mCSPC and mCRPC are being assessed in the Phase I/IIa PETRANHA study (NCT05367440), with the initial data indicated that saruparib (60 mg QD) can be safely combined with enzalutamide,
abiraterone
acetate, or darolutamide
The safety and efficacy of saruparib plus new hormonal agents for the treatment of mCSPC and mCRPC are being assessed in the Phase I/IIa PETRANHA study (NCT05367440), with the initial data indicated that saruparib (60 mg QD) can be safely combined with enzalutamide,
abiraterone
acetate, or darolutamide
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
ADT 's effect on body fat and muscle mass from Life on ADT blog by Richard Wassersug
If a patient is already overweight and diabetic, the paper suggests that, of the two options, they may be better treated with an anti-androgen, like enzalutamide, then with
abiraterone
.
If a patient is already overweight and diabetic, the paper suggests that, of the two options, they may be better treated with an anti-androgen, like enzalutamide, then with
abiraterone
.
Scout4answers
in
Advanced Prostate Cancer
9 months ago
Is there seasonality to testosterone levels?
My ADT treatments (Lupron/
Abiraterone
/Prednisone) ended on May 02 2023 at which point both my PSA and Testosterone were flat lined. Here are the results of the four times I have been tested since the end of the ADT.
My ADT treatments (Lupron/
Abiraterone
/Prednisone) ended on May 02 2023 at which point both my PSA and Testosterone were flat lined. Here are the results of the four times I have been tested since the end of the ADT.
Mascouche
in
Advanced Prostate Cancer
5 months ago
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