Abiraterone Caused High Blood Pressure - Advanced Prostate...

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Abiraterone Caused High Blood Pressure

FightCancer101 profile image
21 Replies

I started Lupron 3 month +Abiraterone + Prednisone almost 4 weeks ago.

In 4 weeks, my Blood Counts went down (see indicators below). My Blood Pressure is higher than before (90 - 148). Medical Oncologist says that it's common for blood pressure to go up and that I should monitor it and start taking High Blood Pressure Medications. I would like to avoid HBP medications as much as possible. And looking for natural remedies and perhaps diet.

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Red Blood Cell Distribution Width (RDW): 12.1 % [Should Be: 12.2 % - 15.1 %] - Low

Platelets: 154 K/mcL [Should Be: 160 K/mcL - 400 K/mcL] - Low

Please, share your experience and how you handle it.

Thank you.

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FightCancer101
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21 Replies
Tall_Allen profile image
Tall_Allen

What is your BP? Serum K? Did they measure aldosterone?

FightCancer101 profile image
FightCancer101 in reply toTall_Allen

My BP 90 to 148. They didn't check Serum and Aldosterone.

Tall_Allen profile image
Tall_Allen in reply toFightCancer101

K= potassium

FightCancer101 profile image
FightCancer101

Potassium, Plasma

3.8 mEq/L

[3.3 mEq/L - 4.9 mEq/L]

MoonRocket profile image
MoonRocket

Since I did 2 years of ADT + zytiga with Prednisone, I can share my experience...High BP runs in the family and I've been on 16mg of Candasartan for 20 years before my diagnosis.

Never had any issues with calcium, potassium, sodium, magnesium, glucose,vAST, ALT or ALP. Always super normal.

BP was normal for me 130s/70s. Occasionally 140s/80s but I'm always higher in the morning and it drops as the day progresses.

Now, after 18 months of taking zytiga and knowing I was stopping treatment in 6 months I asked the MO if I could reduce my Prednisone from 10mg daily to 5mg daily to help with the weaning period when I stopped Zytiga. After making that 5mg reduction, my BP did rise 8 pts.

If your having BP issues, you may want to ask to increase the Prednisone if that option is available to you.

in reply toMoonRocket

Increasing Prednisone has its own issues!! Like rising blood glucose. Insomnia,

MoonRocket profile image
MoonRocket in reply to

Maybe maybe not..but that is a discussion with his MO or PCP

Grandpa4 profile image
Grandpa4

I am someone who never had BP issues. When they put me on these meds they also sent me to a cardiologist whose research interest is in how these drugs increase heart attacks. His job is to minimize my risks. He wanted my BP in the 120s and my LDL well under 100. I have had to take medications to control the BP. I do notice it is easier to control when it is hot outside and I am exceeding extensively outside. This is likely related to salt.

OldGuysRule profile image
OldGuysRule

I never had BP issues in my life until taking Zytiga. I was finally told that to continue taking it that I had to be on BP meds. I just started taking BP meds. 😞

robobob7777 profile image
robobob7777 in reply toOldGuysRule

The more meds, the merrier🤑

Jalbom49 profile image
Jalbom49

My experience was with Lutron, Zytiga and presnisone. Eventually on 5 mg of prednisone my blood pressure want up. When I went to 10 mg, it went down.

When my testosterone was suppressed I eventually developed anemia, which was relieved when I went on testosterone supplement. I was fortunate enough to have undetectable psa for three years when I went on testosterone. Still undetectable after eight months on T.

FightCancer101 profile image
FightCancer101

How to avoid BP medications? Any natural remedies?

robobob7777 profile image
robobob7777 in reply toFightCancer101

Reduce salt, drink water, eat fruit and veggies, exercise, lose weight

swwags profile image
swwags in reply toFightCancer101

yes walk, then work your way up to jogging or some type of more agressive aerobic activity. Cycling, swimming. BP will go down as will cholesterol, etc. Stop eating high processed foods if you do. My rule of thumb is to not eat anything that has more than 5 ingredients on the label but most everything I eat is fresh. Avoid salt. Drink a lot of water. I drink 64 ounces per day before 5 pm. et 30 grams of fiber in you every day! And this last one I can't emphasize enough. Eliminate all stressors to every extent possible. It can be something as easy as turning off the news forever. It can be something hard, such as distancing yourself from toxic people. Accentuate the positive. Eliminate the negative, latch on to the affirmative and don't mess with mister in between. Mindfulness is an overused term but repeating a positive mantra to yourself as you lie down to sleep will calm you as well.

PC-22 profile image
PC-22

I was prescribed it for a while and my BP skyrocketed to around 165 over 130ish. I took pictures to send to my MO. She took me off it and then put me on Erleada instead and no longer have HP issues

Tommyj2 profile image
Tommyj2 in reply toPC-22

You took pictures of HBP?…..of the readings?

PC-22 profile image
PC-22 in reply toTommyj2

Yes, I live in NM but being treated at Mayo in Phoenix AZ. Pictures were to validate readings of which I emailed to my doctor so she could see what I was seeing.

Tommyj2 profile image
Tommyj2 in reply toPC-22

Noted…thanks for the clarification.

jmarsh profile image
jmarsh

my regular doc and a second opinion doc said BP meds would be less detrimental than taking the extra 5 mg of Pred. That’s what I have done. I never had HBP until I started Lupron/Zytiga/Pred

FightCancer101 profile image
FightCancer101 in reply tojmarsh

Thank you. Thats good to know

tunin191319 profile image
tunin191319

What blood pressure medicines or combinations worked ? I'm on zytiga, abi and prednrsione and my blood pressure remains high in the high 140s range, primary care Physician is still stumped, it's been 6 months no drug has worked yet, thank you

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