Experiences with

Abiraterone

Am I correct that when a patient becomes resistant to either enzalutamide or abiraterone, or has to stop due to arrhythmia one cannot be substitued for the other? Other than docetaxel (chemo) are there other commonly used treatments after enzalutamide or abiraterone resistance?

I have been taking Zytiga with 5mg prednisone for 6years now I have had side effects of high blood pressure now I have low Potassium level of 2.7 .has anyone else had this issue. My kidney doctor said double the dose of potassium from 10meq to 20 each day and check level in on week. Oncologist said double

He was on 3 month lupron shot + Abiraterone . Does this means that Abiraterone failed . what are the next steps ahead ? Thank you all for your kind suggestions and reply .

My husband has been on Abiraterone/prednisone for 10 months and Lupron for 12 months and recently has had an increase in his bilirubin 2.5. His MO has stopped the abiraterone temporarily and has ordered a sonogram of his liver/gallbladder and weekly monitoring of bloodwork.

In addition, olaparib offers decreased hypertension when superimposed on ADT + abiraterone acetate + prednisone for mCRPC treatment after prior androgen deprivation from mHSPC therapy.

Commenced abiraterone 1000 mg & prednisone 10mg . Also zoladex implants every 3 months in Feb 2018. Pas down to 0.01 after 3 months. In 2022 I reduced dosage of abiraterone & prednisone by half due to the excessive cost of abiraterone (was self funding) and also strong fatigue side effects.

He was On Abiraterone and Prednisone for exactly 3 years. Dr at City of Hope recommended adding Provenge and continuing Abi and Pres. Any success stories using Provenge with or after Abiraterone? His PSA is 0.029.

When the time comes to stop ADT and abiraterone, for good reasons. Does anyone here have info on abiraterone weaning planning? Including prednisone weaning? TIA

I’ve read some posts here that some guys may have been on abiraterone ten years I’m not trying to blow up the servers.

I was on Lupron and Abiraterone + Pred for 2 years. I completed both in early June, so I am now 5+months post-ADT. My T is only now starting to return (was 32 last week). However, my cortisol levels are still very low.

Have become castrate resistant to abiraterone after 3 1/2 yrs.. Oncologist wants me to stop aby before starting chemo because aby may make chemo less effective, does that sound right?

I was on Abiraterone and prednisone for 6 months until June 6, 2024. My blood work: 4/25/2024 Testosterone 44 ng/dL, PSA undetectable 5/28 T 35, PSA undetectable 6/6 Stopped Abiraterone 7/8 T 968 PSA 0.21 8/19 T 1475 PSA 0.54 My MO want's to do a PSMA scan in a month.

Husbands urology practice does surgery, radiation, ADT but does not list Abiraterone. Their website says they will refer us out if needing chemo. Thoughts?

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2822420 A recent study concludes that Enzalutamide is slightly more beneficial if used before Abiraterone. This is contrary to other studies which some of you have posted recently.

My treatments: brachytherapy, imrt, lupron, abiraterone. SE’s have been tolerable. Have even been able to rebuild muscles after hip replacement, although gained an inch or two at waist. what are pro/cons of 2 yes vs 3yrs of ADT. Should I ask for 3 years?

PC stopped responding to both Abiraterone and Xtandi so I will be starting Docetaxel tomorrow. Has anyone else been in this dilemma and still doing well? It’s

Hi all, My Oncologist took me off of Abiraterone due to my liver enzymes being elevated. Took me off for 2 weeks to see if that helped. It did, but elevated when started again. Started me on Xtandi. Not a fan of Xtandi !

Immediate shot of Lupron and quickly was also put on Abiraterone. Then 28 round of radiation to pelvis and 3 round of SBRT to periaortic. During all of this the MO changed my dosage of Abiraterone to 750 MG along with 5 mg of Prednisone to help with Blood Pressure control.

For the past 7 months I have taken 1000 mg of abiraterone and 10 mg of Prednisone, and tolerated it well. Testosterone has been completely suppressed.

So I fully expected that following my break I would resume both Lupron and abiraterone. The reason I am posting now is that when I decided to go back onto ADT plus abiraterone, my MO only advised me to go back onto ADT, or Lupron.