Experiences with

Abiraterone

He was prescribed a Lupron injection along with 1000 mg of Abiraterone. However, he is experiencing significant vomiting with Abiraterone. Has anyone else had a similar experience? Any tips to manage this?

74 yrs old, initial PSA 16. Biopsy Gleason 4+3 with mets to presacral lymph nodes as per PSMA scan. 45 radiation treatments ended Dec. 2 started Eligard Oct 8. December 23rd PSA 0.16, T <10. Urologist wants to add abi+ prednisone to Eligard for total of 24 months. Currently only minor SE with Eligard

advanced protate cance r…treatment with Abiraterone, pred and lupron psa testosterone ok checkked equasrterly

The study, published on Nature, found that a combination of talazoparib and enzalutamide (TALA + ENZA) may be more effective than other PARP inhibitor combinations, such as olaparib plus abiraterone acetate and niraparib plus abiraterone acetate.

Am I correct that when a patient becomes resistant to either enzalutamide or abiraterone, or has to stop due to arrhythmia one cannot be substitued for the other? Other than docetaxel (chemo) are there other commonly used treatments after enzalutamide or abiraterone resistance?

Also, will be switching from Eligard to Orgovyx, has anyone else taken this combination and can the Orgovyx be taken at the same time as the abiraterone? Thanks guys.

Combining nodularin-R with abiraterone resulted in synergistic inhibition of resistant cancer cells both in vitro and in vivo, indicating that nodularin-R might help overcome abiraterone resistance in CRPC.

I have been taking Zytiga with 5mg prednisone for 6years now I have had side effects of high blood pressure now I have low Potassium level of 2.7 .has anyone else had this issue. My kidney doctor said double the dose of potassium from 10meq to 20 each day and check level in on week. Oncologist said double

Has anybody undergone or undergoing a combination drug of Olaparib 150 mg 2 tabs 2x a day, Abiraterone Acetate 500mg 2 tabs a day, and Prednisone 5mg 1 tab 2x a day?

By using advanced statistical methods to adjust for differences in patient populations across 12 clinical trials, researchers found that this triplet therapy consistently outperformed other commonly used treatments, including abiraterone + ADT + docetaxel, abiraterone + ADT, enzalutamide + ADT, apalutamide

Notably, RM-581 demonstrated superior antiproliferative activity in LAPC-4 cells compared to enzalutamide and abiraterone, two drugs that exhibited a synergistic effect in combination with RM-581. https://www.mdpi.com/2072-6694/15/11/3033

I think I made the CS uncomfortable when I said, "then no not send it, if I must pay you a co-pay, why would I pay you $500 when I can buy 3 months of abiraterone for that same $500?"

Truqap (capivasertib), an AKT inhibitor, combined with abiraterone and androgen deprivation therapy (ADT) has shown promise in treating men with a specific subtype of prostate cancer called PTEN-deficient metastatic hormone-sensitive prostate cancer (mHSPC).

He was On Abiraterone and Prednisone for exactly 3 years. Dr at City of Hope recommended adding Provenge and continuing Abi and Pres. Any success stories using Provenge with or after Abiraterone? His PSA is 0.029.

After PSA started to raise, the MO added Abiraterone 1000 mg. a day with 10 mg prednisolone to his treatment regimen with Zoladex (once every 3 month) and Zoledronic acid (once every month).

How long does it take abi to start reducing PSA? I started 4 weeks ago and PSA is still rising.

In our experience, enzalutamide is less effective if patients were previously treated with abiraterone AND they have high level of ctDNA. On the contrary, patients receiving docetaxel after abiraterone have similar outcomes regardless of their starting ctDNA level.

My MO is changing my off of Abiraterone to Xtandi and wants to add Talzenna to my regime. Reading the FDA report on this 'new med' is scary and wondering if anyone in the community has used it and what side effects it gave them. Thank you for your response.

I was on Lupron and Abiraterone + Pred for 2 years. I completed both in early June, so I am now 5+months post-ADT. My T is only now starting to return (was 32 last week). However, my cortisol levels are still very low.

Treatment included imrt 25x to the pelvic floor, abiraterone and lupron injection monthly. Undetectable psa until yesterday. I know at 0.05 the level is very low. It does appear to be my 3rd bcr. What are the next in Treatment protocols? Thank you. I'm receiving care at MSK in nyc.