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Experiences with
Abiraterone
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My husband's experience with Xtandi
In April he was put on
Abiraterone
+ Prednisone, and after three months of continued rising PSA the doc switched him to Xtandi + Prednisone. The
abiraterone
was not so good--lots of fatigue--but the Xtandi was TERRIBLE. Husband had zero energy: literally taking a nap would exhaust him.
In April he was put on
Abiraterone
+ Prednisone, and after three months of continued rising PSA the doc switched him to Xtandi + Prednisone. The
abiraterone
was not so good--lots of fatigue--but the Xtandi was TERRIBLE. Husband had zero energy: literally taking a nap would exhaust him.
WildRose6
in
Advanced Prostate Cancer
4 years ago
A high Neutrophil-to-Lymphocyte Ratio [NLR] is a poor prognostic factor for CRPC patients on Abiraterone [Abi] or Enzalutamide [Enz].
New study below [1]. I posted a review of the NLR-PCa literature 4 years ago: https://healthunlocked.com/advanced-prostate-cancer/posts/134756331/inflammation.-1-neutrophil-to-lymphocyte-ratio-nlr There have been similar studies since then. In the latest, from Japan: "A higher NLR was associated with
New study below [1]. I posted a review of the NLR-PCa literature 4 years ago: https://healthunlocked.com/advanced-prostate-cancer/posts/134756331/inflammation.-1-neutrophil-to-lymphocyte-ratio-nlr There have been similar studies since then. In the latest, from Japan: "A higher NLR was associated with
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Free vs Total Testosterone? - Redux.
in 47% of patients in the
abiraterone
arm, while none of the patients continuing regular androgen deprivation exhibited serum testosterone levels below the detection threshold.
in 47% of patients in the
abiraterone
arm, while none of the patients continuing regular androgen deprivation exhibited serum testosterone levels below the detection threshold.
pjoshea13
in
Advanced Prostate Cancer
4 years ago
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Yesterday's 2 month PSA reads vs Sept 18th. A 0.051ng/mL Delta increase. Should I be concerned?? Seee my newest Med/Onc this Friday.
I sent my newest Med/Onc a msg with some of my ADT (
Abiraterone
250mg, Lupron(Eligard), prednisone 5mg 2X/day) He evidently did not see them as positive and ordered me; 1) CT scan abs/pelvis/chest 2) NM technicium bone scan and new set of labs, including TSH(thryoid).
I sent my newest Med/Onc a msg with some of my ADT (
Abiraterone
250mg, Lupron(Eligard), prednisone 5mg 2X/day) He evidently did not see them as positive and ordered me; 1) CT scan abs/pelvis/chest 2) NM technicium bone scan and new set of labs, including TSH(thryoid).
depotdoug
in
Advanced Prostate Cancer
3 years ago
PSA still rising whilst on Abiraterone
Since I started
Abiraterone
the monthly PSAs 11.7 12.9 6.6 4.2 4.1 4.3 4.9 and the last from Monday is 5.2 I asked previous MO about switching to Dexamethasone and he said wouldn't hurt to try. Awaiting my Kaiser MO response Fight on Brothers Randy My pic from Lupron shot last Friday 😂
Since I started
Abiraterone
the monthly PSAs 11.7 12.9 6.6 4.2 4.1 4.3 4.9 and the last from Monday is 5.2 I asked previous MO about switching to Dexamethasone and he said wouldn't hurt to try. Awaiting my Kaiser MO response Fight on Brothers Randy My pic from Lupron shot last Friday 😂
dockam
in
Advanced Prostate Cancer
4 years ago
Newly Diagnosed - Advanced Stg Prostrate Cancer.
Started wit ADT (Degarelix) and
Abiraterone
with Prednisone since Ist July 2020. My PSA readings ----25 Jun 2020---258, 27 July2020---7.8, 25 Aug 2020---2.8. I have undergone tests for BRACA 1 & 2 yesterday and the results are awaited.
Started wit ADT (Degarelix) and
Abiraterone
with Prednisone since Ist July 2020. My PSA readings ----25 Jun 2020---258, 27 July2020---7.8, 25 Aug 2020---2.8. I have undergone tests for BRACA 1 & 2 yesterday and the results are awaited.
doklam2017
in
Advanced Prostate Cancer
4 years ago
Having SABR radiotherapy to 61mm met on my hip
The issue is that it hasn't shrunk so that is why they will do the SABR treatment, ie the
Abiraterone
is not working on the bone met. Is it possible to remove that size of tumour with SABR?
The issue is that it hasn't shrunk so that is why they will do the SABR treatment, ie the
Abiraterone
is not working on the bone met. Is it possible to remove that size of tumour with SABR?
konichiwa12
in
Advanced Prostate Cancer
4 years ago
Abiraterone vs Enzalutamide + Radiation
One of my oncologists suggested that either
abiraterone
or enzalutamide could be used but noted that prednisone must be taken with
abiraterone
, and it is well known that prednisone is immunosppressive.
One of my oncologists suggested that either
abiraterone
or enzalutamide could be used but noted that prednisone must be taken with
abiraterone
, and it is well known that prednisone is immunosppressive.
PhilipSZacarias
in
Advanced Prostate Cancer
4 years ago
Dexamethasone+abiraterone along with lu psma treatment
Due to covid 19,we have decided to postpone my dad's 2nd lu psma treatment.The first cycle was administered on 26th feb.He is currently continuing
abiraterone
+prednisone combo.His psa has been rising since july.Is it a good idea to switch to dexamethasone (with
abiraterone
)until we are able to travel
Due to covid 19,we have decided to postpone my dad's 2nd lu psma treatment.The first cycle was administered on 26th feb.He is currently continuing
abiraterone
+prednisone combo.His psa has been rising since july.Is it a good idea to switch to dexamethasone (with
abiraterone
)until we are able to travel
Vsahay
in
Advanced Prostate Cancer
4 years ago
SPARTAN - Overall Survival.
"In SPARTAN, patients who progressed to metastatic disease were offered treatment with
abiraterone
acetate plus prednisone; >70% of patients in either arm received study-sponsored
abiraterone
acetate plus prednisone as the first subsequent therapy after progression (Supplementary Table 3).
"In SPARTAN, patients who progressed to metastatic disease were offered treatment with
abiraterone
acetate plus prednisone; >70% of patients in either arm received study-sponsored
abiraterone
acetate plus prednisone as the first subsequent therapy after progression (Supplementary Table 3).
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Our Saga so far...and an observation about quality of care
Five months of
Abiraterone
and Xtandi have left him almost completely drained of energy. On the old ADT he kept very active, working outside every day, hiking, etc. but now he can't do much of anything.
Five months of
Abiraterone
and Xtandi have left him almost completely drained of energy. On the old ADT he kept very active, working outside every day, hiking, etc. but now he can't do much of anything.
WildRose6
in
Advanced Prostate Cancer
4 years ago
BAT
More recent trials showed a further increase in overall survival when enzalutamide or
abiraterone
are associated with androgen deprivation therapy in hormone-sensitive disease.
More recent trials showed a further increase in overall survival when enzalutamide or
abiraterone
are associated with androgen deprivation therapy in hormone-sensitive disease.
podsart
in
Advanced Prostate Cancer
4 years ago
Zoladex and Enzalutamide?
We took a long shot and asked if he could be placed on
abiraterone
along with this as the NHS are currently offering this in place of chemo but they refused but have offered him enzalutamide as an alternative. He also asked if he could be placed on zometa but she refused to put him on this.
We took a long shot and asked if he could be placed on
abiraterone
along with this as the NHS are currently offering this in place of chemo but they refused but have offered him enzalutamide as an alternative. He also asked if he could be placed on zometa but she refused to put him on this.
Hillwalker87
in
Advanced Prostate Cancer
4 years ago
New research from Au
https://news.griffith.edu.au/2020/08/06/new-anti-cancer-drug-breakthrough-for-prostate-cancer/ Picked up
Abiraterone
, MO moving monthly liver panel out to three months💙 PSA up to 4.9 from 4.3 last month T <3 😔 Time will tell Mahalo Fight on Brothers Randy
https://news.griffith.edu.au/2020/08/06/new-anti-cancer-drug-breakthrough-for-prostate-cancer/ Picked up
Abiraterone
, MO moving monthly liver panel out to three months💙 PSA up to 4.9 from 4.3 last month T <3 😔 Time will tell Mahalo Fight on Brothers Randy
dockam
in
Advanced Prostate Cancer
4 years ago
Research Study with Niaparib in combination with Abiraterone Acetate and Prednisone
Has anyone been involved with a Research Study with Niaparib in combination with
Abiraterone
Acetate and Prednisone? I am considering It. It is double blind phase 3 study.
Has anyone been involved with a Research Study with Niaparib in combination with
Abiraterone
Acetate and Prednisone? I am considering It. It is double blind phase 3 study.
DER326
in
Advanced Prostate Cancer
4 years ago
I Can Do an Oil Change
In other news, I completed chemo back in June, finished radiation in July, and continue on Atezolizumab, Lupron,
Abiraterone
, and Xgeva. I'm finally beginning to see glimpses of improving health as I recover from the chemo and radiation.
In other news, I completed chemo back in June, finished radiation in July, and continue on Atezolizumab, Lupron,
Abiraterone
, and Xgeva. I'm finally beginning to see glimpses of improving health as I recover from the chemo and radiation.
tom67inMA
in
Advanced Prostate Cancer
4 years ago
Fast heartbeats with abiraterone-another update
Recap, fast heartbeats 120/130 per min, oncologist stops aberaterone. Angiogram heart - mild artery disease, sinus arrhythmia atrial flutter. Cardiologist adds digoxin and apixaban. Not bad for 76 year old smoker also enjoys social drink. 19 days later oncologist restarts Aberaterone. 4days later heartbeats
Recap, fast heartbeats 120/130 per min, oncologist stops aberaterone. Angiogram heart - mild artery disease, sinus arrhythmia atrial flutter. Cardiologist adds digoxin and apixaban. Not bad for 76 year old smoker also enjoys social drink. 19 days later oncologist restarts Aberaterone. 4days later heartbeats
Dondodoc
in
Advanced Prostate Cancer
4 years ago
Adverse Events Related to Abiraterone and Enzalutamide Treatment
Clinicians should consider these data when treating cancer patients with
abiraterone
and enzalutamide.
Clinicians should consider these data when treating cancer patients with
abiraterone
and enzalutamide.
Balsam01
in
Advanced Prostate Cancer
4 years ago
Abiraterone NHS
Does anybody know if the NHS offer
abiraterone
as a first line treatment along with Zoladex? Also, I hear that doing this can be beneficial. Does anybody know how so? Why would it be any better than adding it later on as a second tier? Many thanks in advance!
Does anybody know if the NHS offer
abiraterone
as a first line treatment along with Zoladex? Also, I hear that doing this can be beneficial. Does anybody know how so? Why would it be any better than adding it later on as a second tier? Many thanks in advance!
Hillwalker87
in
Advanced Prostate Cancer
4 years ago
What Tx options after resistance to Xtandi?
Hi, My dad (74yo) has developed resistance to Xtandi after 1year of success. now his PSA is 11 and his Dr is suggesting to just continue on Xtandi, and wait until there are symptoms to start chemo (for now he is chemo naive and never had
abiraterone
) anyone had good outcomes from some Tx after Xtandi
Hi, My dad (74yo) has developed resistance to Xtandi after 1year of success. now his PSA is 11 and his Dr is suggesting to just continue on Xtandi, and wait until there are symptoms to start chemo (for now he is chemo naive and never had
abiraterone
) anyone had good outcomes from some Tx after Xtandi
Tokyoite
in
Advanced Prostate Cancer
4 years ago
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