I am currently going through a BAD UC flare. Taking 40mg of Prednisone and my daily Lialda pills. My bladder feels like it's under tremendous pressure, which makes me take several trips to the bathroom for a disappointing amount of urine to come out. Has anyone ever had this issue with a UC flare? I went to a CVS minute clinic and did a urine sample there. I had a trace of leukocytes in my urine, so they prescribed Macrobid. I feel like absolute crap. Can someone lead me in the right direction on this?