So been to the hospital now, thanks for the tip about taking a book, it was needed, PBC diagnosis confirmed and put me straight on ursodeoxycholic acid. Doing more bloods and going for MRI and dexoscan follow up appointment in a couple of months to see how I am getting on. I read that a side effect of the urso is diarrhea but it seems to have has the opposite effect and I have constipation. Is there anyone who has experienced the same? I drink water and have prunes with breakfast every day is there anything else I can do or take? Any suggestions gratefully received.