Experiences with

Urso

Although I struggled at first with Urso, and had to start with a slow dose increase (adding half a tablet every 15 days), my alkaline phosphatase (ALK) levels have dropped from 345 to 166 in 2 months. I’m especially grateful for all the advice and support I received here.

I’ve been diagnosed with PBC years ago but started taking Urso few months ago. My liver enzymes and ALP are normal, however my TSH (thyroid) level has been going up drastically after Urso and my Synthroid dosage is being altered accordingly. Has anyone experienced TSH change after being in Urso?

Hello, I currently take 3-300mg capsules of Urso per day. I have always tolerated this medication without any problems, however, now I’m having issues. These are pink and white capsules manufactured by Epic. I don’t feel like I’m digesting the thick shell on these.

Did you ever begin Urso again and what damage, if any, did it do to your liver?

hi guys has anybody had their Fibroscan scores improved after taking urso? eleni

Dr. wants to supplement my URSO with it. I take 1000mg a day of URSO, but my ALP level is still elevated. 178. The side effects of this drug scare the heck out of me! As of now. All blood work is normal, except ALP. Ultrasound is good, and Fibroscan was great.

Hi Just wondering if anyone stopped their Urso for a week to see if it helped with stomach issues. I've been on it now for 2 years and my numbers are all good since last August.

I’ve just started 80mg of elafribnor with a 1000mg of Urso also… Just wondered if anyone has had any good results with it thanks

I have been on Urso since my diagnosis. I take 600 mg daily. I had lab a week ago & don't have the results but I decided to quit the Urso. My liver enzymes has never gotten anywhere near normal. They have come down. I'm just stopping the Urso for a few months & then have lab drawn.

I started methotrexate a few weeks ago and I’m trying to get used to that, and now I’ve been told after many years of dodging it, that I have to start urso as my alk phos has been elevated all year and I have a large risk of severe fibrosis.

[/i] [i]Some take the at night, as this may help eliminate your feelings of nausea since you are sleeping.[/i] [i]ALWAYS make sure you are taking the right dose of when you get to your prescribed dose.

I was diagnosed with PBC 4 years ago and prescribed Urso acid. Just recently I have had more frequent migraines and also nosebleeds. Nosebleeds aren’t a big deal, and more a constant trickle of blood for a few minutes. thanks in advance for any replies

Have been on Urso about 5 years. My specialty pharmacy will no longer have so they didn't refill and didn't notify me. As a result no meds for 2 months. Have gained nearly 20 lbs. Am trying to get gastro to find me new pharmacy. In the meantime worried about weight gain. Any thoughts?

With urso, diet and life style adjustments. My blood is in total check. Today I was diagnosed with endometrial cancer and was wondering if anyone in the group have PBC and cancer and how coop with it. Any comment is much appreciated. Thank you

Does anyone in the UK know if the secondary drug that can be used with Urso, called Livdelzi, is available yet in the UK? And if so, is it available on a regular NHS prescription?

Hi, I was diagnosed with PBC last year and am on urso, I have no symptoms and keep well and would like to go abroad on holiday this year. Two companies I've tried to get a quote from have refused me , I also have asthma which is really well controlled.

[/i][/u][i] I heard at a PBC conference last year that half of the patients who take are on the wrong dosage. If you aren't, make sure you let your doctor know - ask why you aren't? This is crucial![/i]

I am an Urso responder and therefore my liver readings fall within the normal range. I only know of the narrowed arteries as I took part in heart research. Despite being healthy, trying to get travel insurance was a challenge being given quotes in excess of £2,000. Is this normal.?

I was diagnosed with PBC in September and started Urso thereafter. My bloods have all come back to normal range so I guess I’m an Urso responder which is great.

I'm on Urso, and my ALP and other liver enzymes are now all in the normal ranges. While I fully intend to ask my doctor, I'm wondering if any of you take glucosamine and/or chondroitin supplements for joints. I've noticed my shoulders are a bit "crackly and creaky" lately.