Experiences with
Ursodeoxycholic acid4,283 public posts
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Two updates in the Guidelines for PBC
Fibrates can be considered as off‐label alternatives for patients with PBC and inadequate response to ursodeoxycholic acid, although fibrates are discouraged in patients with decompensated liver disease.
10. OCA is contraindicated in patients with advanced cirrhosis.
Exciting!
Food and Drug Administration (FDA) for investigational treatment, seladelpar, for the management of primary biliary cholangitis, including pruritus in adults without cirrhosis or with compensated cirrhosis (Child Pugh A) who are inadequate responders or intolerant to ursodeoxycholic acid (UDCA).
Disability information
Biliary CirrhosisPrimary Biliary Cirrhosis – Condition and Symptoms
The liver secretes bile, a bodily fluid that is essential for the body to digest fats. It also helps the body to rid itself of toxic substances, cholesterol, and worn-out red blood cells. The ducts that release bile can become damaged