Hi I’m new here. Have had RA for 20 years plus more if you count undiagnosed. Have tried Methatrexate, Sulph, Cimzia, Enbrel, too many steroid injections to remember. Now in Abatercept infusions and started Leflunomide 2 weeks ago. I feel like I have a permanent hangover and my joints are so sore. I have 3 boys and a virtually full time job but have no help from my husband with the boys or the house. I’m at breaking point... he has no sympathy and no thought to help me in any way. Don’t know what to do any more.