Posts - Fight Prostate Cancer | HealthUnlocked

Fight Prostate Cancer

2,800 members • 1,030 posts

All posts for May 2023

Something for those of us who struggle with the deeper analyses of our fellows--behavior factors affecting PCa survival

https://pubmed.ncbi.nlm.nih.gov/36028533/ Results: Over a median 10.2 years, we observed 219 PCa deaths. Each additional point of one of the PCa-specific...

https://pubmed.ncbi.nlm.nih.gov/36028533/ Results: Over a median 10.2 years, we...

•11 months ago

Not the odd one out any more

A very knowledgeable source informed me about a multi-institutional UK trial using dose adjustment in ovarian cancer. Does it ring any bells to you? "How...

A very knowledgeable source informed me about a multi-institutional UK trial usi...

•11 months ago

Certain Toxic Effects Higher With Newer PCa Therapies— Reviews suggests increased risks of cognitive adverse events, fatigue, falls

No time to thoroughly read and write this one up, but wanted to get it out for review and comment. Certain Toxic Effects Higher With Newer Prostate Cancer...

No time to thoroughly read and write this one up, but wanted to get it out for r...

•11 months ago

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The emerging role of fatty acid binding protein 5 (FABP5) in cancers

New paper [1]. Every now & then we see a paper claiming that, if only we could inhibit a particular protein, cancer would be more manageable. Here's another:...

New paper [1]. Every now & then we see a paper claiming that, if only we could ...

•11 months ago

Blue Sky News - Prostate Cancer Foundation of Australia - April 2023

While, as has been the case for previous editions of this publication, most of the information is mainly relevant to readers from Oz, some items might be of...

While, as has been the case for previous editions of this publication, most of t...

•11 months ago

Range bounded adaptive therapy: abiraterone etc

Hi, Wondering if I can persuade myself to take abiraterone for recently confirmed mcrpc. Looking to maybe use range bounded adaptive ther. Has anyone...

Hi, Wondering if I can persuade myself to take abiraterone for recently confirme...

•11 months ago

Aplautamide, enzalutamide: low dose opinions

Hi Officially mcrpc. Can't get darolutamide so faced with choice of zytiga, xtandi or aplautamide in the coming weeks. Faced with the first two I would have...

Hi Officially mcrpc. Can't get darolutamide so faced with choice of zytiga, xta...

•11 months ago

Aging: Papers on diet, exercise, and caloric restriction effects on microbiome and epigenome

The following two articles were included in post by a member over at the HU CLLSupport site. (Thanks, Kwenda.) Both are review papers that look at the effects...

The following two articles were included in post by a member over at the HU CLLS...

•11 months ago

Prostate Cancer, Nutrition, and Dietary Supplements , Medscape, Drugs & Disease, Urology, Updated Jan 26, 2023.

This comprhensive review by U of MI's Dr. Mark A Moyad on PCa and Nutrition & Diet is by far the best Overview of the various topics I have yet read. It is too...

This comprhensive review by U of MI's Dr. Mark A Moyad on PCa and Nutrition & Di...

•11 months ago

Finally Undetectable PSA on BAT

Happy to share my latest progress report. Note that I am mHSPC, lymph nodes only to pelvis and abdomen. I have been on long-cycle modified BAT for 2.5 years...

Happy to share my latest progress report. Note that I am mHSPC, lymph nodes only...

•11 months ago

Caffeic acid phenethyl ester [CAPE]

New study [1]. "Caffeic acid phenethyl ester suppresses EGFR/FAK/Akt signaling, migration, and tumor growth of prostate cancer cells" There have been...

New study [1]. "Caffeic acid phenethyl ester suppresses EGFR/FAK/Akt signaling,...

•11 months ago

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Unmetabolized Estrogen (Depurinated Adducts) How I got PCa and how to prevent and detect it.

3 months before I got diagnosed with PCa in May of 2013 I had been feeling tired with no libido. I will bypass my health care profession system failures as it...

3 months before I got diagnosed with PCa in May of 2013 I had been feeling tired...

•11 months ago

Melatonin and Prostate Cancer: Anti-tumor Roles and Therapeutic Application

New paper offers a nice review of why one might use melatonin against PCa. Section 3 lists ten reasons. [1] 19 years ago, the Life Extension PCa protocol...

New paper offers a nice review of why one might use melatonin against PCa. Sect...

•1 year ago

Ivermectin on Pub Med

{From a related web site} In summary, our results indicate that ivermectin suppressed the AR and E2F signaling pathways and DNA damage repair capacity by...

{From a related web site} In summary, our results indicate that ivermectin supp...

•1 year ago

Targeting the formation of estrogens for treatment of hormone dependent diseases–current status

New study [1] - (Slovenia & Netherlands). 27 references to "prostate", but not very illuminating. Except that estrogen is rarely mentioned in PCa papers....

New study [1] - (Slovenia & Netherlands). 27 references to "prostate", but not ...

•1 year ago

Strategies to Re-Sensitize Castration-Resistant Prostate Cancer to Antiandrogen Therapy

New paper from Spain [1]. "... we will review those strategies and drugs that are able to resensitize cancer cells to previously used treatments through the...

New paper from Spain [1]. "... we will review those strategies and drugs that a...

•1 year ago

Vitamin D doses

https://www.youtube.com/watch?v=E3_t-EQIy0s I can attest to the long stretch of time it takes for D3 supplementation to plateau. More than one year for me,...

https://www.youtube.com/watch?v=E3_t-EQIy0s I can attest to the long stretch of...

•1 year ago

Selective amino acid restriction therapy (SAART)

This is a follow-on from something that came up in the "Cysteine depletion sensitizes prostate cancer cells to agents that enhance DNA damage and to immune...

This is a follow-on from something that came up in the "Cysteine depletion sensi...

•1 year ago

Moringa oleifera methanolic leaves extract induces apoptosis

This may be helpful, retrieved from Jane McClelland's facebook page. https://pubmed.ncbi.nlm.nih.gov/32588472/ Moringa oleifera methanolic leaves extract...

This may be helpful, retrieved from Jane McClelland's facebook page. https://pu...

•1 year ago

Caprylic Acid promotes the progression of prostate cancer.

New study below [1]. Long-term vilification of saturated fats have led us to be afraid of longer-chain fats, such as (the innocent) stearic acid (C16:0). The...

New study below [1]. Long-term vilification of saturated fats have led us to be...

•1 year ago

Cysteine depletion sensitizes prostate cancer cells to agents that enhance DNA damage and to immune checkpoint inhibition

New paper below [1]. I have always been interested in ways in which a treatment might be enhanced by supplements or dietary changes. (or repurposed drugs)...

New paper below [1]. I have always been interested in ways in which a treatment...

•1 year ago

Viewray treatment costs

Anyone have a ballpark $ amount for out of pocket Viewray treatment for PCa at UCLA? I’m a Kaiser patient and Viewray sounds superior to the Truebeam they...

Anyone have a ballpark $ amount for out of pocket Viewray treatment for PCa at U...

•1 year ago

sudden stop in PSA decline

I‘ve been doing IADT, and started relugolix in December 2022, with PSA 7.48, and each monthly PSA decline since then was significant and reassuring. Here’s the...

I‘ve been doing IADT, and started relugolix in December 2022, with PSA 7.48, and...

•1 year ago

Oligo

Where in the world would you go for treatment and/or second opinion for oligometastatic prostate cancer? If you could go anywhere.

Where in the world would you go for treatment and/or second opinion for oligomet...

•1 year ago

Fasting Insulin.

The latest Life Extension magazine has a lead article on fasting insulin. With insulin resistance, the pancreas produces increased amounts of insulin (as long...

The latest Life Extension magazine has a lead article on fasting insulin. With ...

•1 year ago

The human microbiome links to prostate cancer risk and treatment (Review)

New study below [1]. Abstract. Prostate cancer (Pca) is the second most common cancer type worldwide. Microorganisms colonized in different body...

New study below [1]. Abstract. Prostate cancer (Pca) is the second most comm...

•1 year ago

Comparison of Cancer Mortality and Incidence Between New Zealand and Australia

New study below [1]. I know a few this will interest. "New Zealand's total cancer incidences were lower than those expected from Australia's in both women...

New study below [1]. I know a few this will interest. "New Zealand's total can...

•1 year ago

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Power Grid stability

At first, it will sound as irrelevant to PCa, but my belief is that the medical community should learn from other industries when prescribing dosages. In a nut...

At first, it will sound as irrelevant to PCa, but my belief is that the medical ...

•1 year ago

Metformin: crpc why continue

Hi last PSA 8.1 with psadt of 1.5 months so waiting for inevitable crpc news. Wondering why I should continue with Metformin which has caused me b12...

Hi last PSA 8.1 with psadt of 1.5 months so waiting for inevitable crpc news. Wo...

•1 year ago

Gut Microbiome Varies Hour to Hour, Month to Month - Intraindividual shifts over time may explain why drugs don't work the same in everyone

Gut Microbiome Varies Hour to Hour, Month to Month - Intraindividual shifts over time may explain why drugs don't work the same in everyone, MedPage...

Gut Microbiome Varies Hour to Hour, Month to Month - Intraindividual shifts over...

•1 year ago

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