Posts - Fight Prostate Cancer | HealthUnlocked

Fight Prostate Cancer

2,956 members•1,313 posts

All posts for November 2024

Preclinical, interesting and easy to implement: kaempferol shows promise in treating emotional stress-aggravated prostate cancer metastasis

Kaempferol, a key active ingredient in the traditional Chinese medicine formula Chaihu-Shugan-San (CSS), shows promise in treating emotional stress-aggravated...

Kaempferol, a key active ingredient in the traditional Chinese medicine formula ...

•2 months ago

NP18: a potential new weapon against prostate cancer, from the future!

Ok, just joking, I said from the future because the source is going to be published in January 2025. NP18 is a promising new PROTAC degrader that targets the...

Ok, just joking, I said from the future because the source is going to be publis...

•2 months ago

AI designs another cancer drug! Let’s go baby!

I need Don Pescado to scream “The science is cooooomingggg!!” Insilico does it gain…it’s the 10th AI generated drug they created that reaches clinical stage!...

I need Don Pescado to scream “The science is cooooomingggg!!” Insilico does it g...

•2 months ago

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Newsletter link

I have added a section "Newsletters" in the menu at prostatewarriors.com That page will be filled with all the newsletter I will be publishing. So if you want...

I have added a section "Newsletters" in the menu at prostatewarriors.com That p...

•2 months ago

Today I need to cheer up a bit so...here is where we are heading with survival for de novo metastatic prostate cancer!

It's PSA week, so of course I get anxious...but here are the numbers of an observational study which spreads of a 26 years timeframe. "Median overall survival...

It's PSA week, so of course I get anxious...but here are the numbers of an obser...

•2 months ago

Preclinical: new 3-in-1 ADC with a completely different approach is ready to move to clinical stage

Not clinical yet, but pan-cancer approach, in a market (ADCs market) that is ramping up, so we can expect news soon! This article discusses a promising new...

Not clinical yet, but pan-cancer approach, in a market (ADCs market) that is ram...

•2 months ago

Phase III CAPItello-281 trial: positive results for PTEN mutated prostate cancer for capivasertib

Truqap (capivasertib), an AKT inhibitor, combined with abiraterone and androgen deprivation therapy (ADT) has shown promise in treating men with a specific...

Truqap (capivasertib), an AKT inhibitor, combined with abiraterone and androgen ...

•2 months ago

Less is not always good! Rethinking (bad) cholesterol levels.

With all the limits involved, which are: 1 - it's a retrospective study, not controlled or interventional 2 - it's talking about prostate cancer risk, and we...

With all the limits involved, which are: 1 - it's a retrospective study, not co...

•2 months ago

Second newsletter

Ok, I had to rush it a bit, but I have just sent it! As usual, check in your SPAM folder! Have a great weekend! Max

Ok, I had to rush it a bit, but I have just sent it! As usual, check in your SP...

•2 months ago

Anyone who took DCA?

Hi all. Just would like to know any feedback on DCA. Thanks

Hi all. Just would like to know any feedback on DCA. Thanks

•2 months ago

Ali Bashashati & Septimiu Salcudean on PCa Risk Assessment With AI - Machine learning model tested better against Gleason grading & CAPRA

Hey, Max73. You missed one . . . and one right up your AI alley! Salcudean and Bashashati: "In general, AI tools learn from prior examples,...

Hey, Max73. You missed one . . . and one right up your AI alley! Salcudean and ...

•2 months ago

In vivo: Nodularin-R Enhances Abiraterone's Effectiveness Against Castration-Resistant Prostate Cancer

another door opens, hopefully a good one… Researchers found that high expression of the PPP1CA gene is linked to a worse prognosis for patients. They...

another door opens, hopefully a good one… Researchers found that high expressi...

•2 months ago

Predicting Olaparib Resistance in Prostate Cancer Patients

Scientists at The Institute of Cancer Research, London, have figured out a way to predict how long prostate cancer patients will benefit from the drug olaparib...

Scientists at The Institute of Cancer Research, London, have figured out a way t...

•2 months ago

ARANOTE trial: FDA accepts sNDA of darolutamide + ADT for metastatic hormone-sensitive prostate cancer

The FDA has accepted a supplemental New Drug Application (sNDA) for darolutamide (Nubeqa) in combination with androgen deprivation therapy (ADT) for the...

The FDA has accepted a supplemental New Drug Application (sNDA) for darolutamide...

•2 months ago

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Phase 3 trial for localized prostate cancer should be completed in December 2024

CAN-2409 is an immunotherapy drug currently in a Phase 3 clinical trial (PrTK03, NCT01436968) for individuals with intermediate-high risk localized prostate...

CAN-2409 is an immunotherapy drug currently in a Phase 3 clinical trial (PrTK03,...

•2 months ago

Phase 3 trial AMPLITUDE about castration-sensitive prostate cancer should be completed by the end of November 2024

The AMPLITUDE clinical trial (NCT04497844) is evaluating the effectiveness of Akeega, a combination of the PARP inhibitor niraparib and abiraterone acetate,...

The AMPLITUDE clinical trial (NCT04497844) is evaluating the effectiveness of Ak...

•2 months ago

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Phase 3 clinical trial: EZH2 inhibitor to fight castration resistant prostate cancer

I am a bit slow, I am in Poland for work so I have to carve in the time to post. Mevrometostat (PF-06821497) is an experimental drug being investigated in a...

I am a bit slow, I am in Poland for work so I have to carve in the time to post....

•2 months ago

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Preclinical: EZH2 a new potential target for Castration-Resistant Prostate Cancer

NOTE. This is the first time I have seen this this happening. I have found this new article, and…before I found this article, I have found a phase 3 clinical...

NOTE. This is the first time I have seen this this happening. I have found this ...

•2 months ago

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Multi-tracer PET imaging could change treatment paths

This could literally save lives just by understanding the individual nature of each prostate cancer and metastasis. A study that used whole-body PET imaging...

This could literally save lives just by understanding the individual nature of e...

•2 months ago

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CTT2274: another potential (heavy) weapon against prostate cancer

Let's keep hoping... A Seattle-based biotech firm, has received a $2.4 million grant to develop CTT2274, a new drug for metastatic prostate cancer. CTT2274 is...

Let's keep hoping... A Seattle-based biotech firm, has received a $2.4 million ...

•2 months ago

From Norway with love: preclinical immune therapy enhancer ready for phase 1

A new research from Oslo University focuses on a new combination therapy for prostate cancer that uses a checkpoint inhibitor and an IRE1 blocker called...

A new research from Oslo University focuses on a new combination therapy for pro...

•2 months ago

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Please check your email inbox

I have tried to send my first newsletter to the people who registered for it on Prostate Warriors, if you have not received it, please check your spam folder....

I have tried to send my first newsletter to the people who registered for it on ...

•2 months ago

The Role of HSD3B1 in Prostate Cancer Progression and Treatment

I don't think I was tested against this gene, so I think it could be important for me as well. A common genetic variation called the adrenal-permissive allele...

I don't think I was tested against this gene, so I think it could be important f...

•3 months ago

New promising approach (Phase 2 completed) to delay next-line systemic therapy in mCRPC: MEDCARE trial

The MEDCARE trial examined the effectiveness of PDT in delaying the need for NEST (Next-line Systemic Therapy) in patients with oligoprogressive mCRPC....

The MEDCARE trial examined the effectiveness of PDT in delaying the need for NES...

•3 months ago

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Phase 3 ended: ECLIPSE trial of 177Lu-PSMA-I&T

A phase 3 clinical trial called ECLIPSE has shown that 177Lu-PSMA-I&T significantly extends the median radiographic progression-free survival (rPFS) compared...

A phase 3 clinical trial called ECLIPSE has shown that 177Lu-PSMA-I&T significan...

•3 months ago

Инвермектин.

Здравствуйте. Поделитесь своим опытом, кто нибудь принимает инвермектин? Какой дозой, сколько времени и есть ли нежелательные последствия?

Здравствуйте. Поделитесь своим опытом, кто нибудь принимает инвермектин? Какой д...

•3 months ago

Travel after SBRT

Can one fly after SBRT treatments are done? Looking for others experience.

Can one fly after SBRT treatments are done? Looking for others experience.

•3 months ago

Bacteria to fight cancer: new approaches

We talked yesterday about bacteria to fight cancer, here is a new approach (of course preclinical still). We are talking about entering clinical trials within...

We talked yesterday about bacteria to fight cancer, here is a new approach (of c...

•3 months ago

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Combination therapy increases OS for neuroendocrine prostate cancer patients

Small study but clinical. I don't even know if it could be called phase 1, but at least on humans. The study, published in Cell Reports Medicine, focuses on a...

Small study but clinical. I don't even know if it could be called phase 1, but a...

•3 months ago

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"Food as Medicine" Research from City Of Hope is in Phase 2, eat them mushrooms!

Ok, it's from City of Hope, I am sure they are a great cancer institution, but I did not like the hype created around AOH1996 (where are the phase 1 results...

Ok, it's from City of Hope, I am sure they are a great cancer institution, but I...

•3 months ago

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