Posts - Fight Prostate Cancer | HealthUnlocked

Fight Prostate Cancer

2,801 members • 1,030 posts

All posts for April 2023

FDA Panel Rejects Broad Olaparib Indication in Metastatic CRPC — ODAC votes that olaparib-abiraterone comb be restricted to BRCA+ subset

Possible good news on the way for BRCA-mutated PCa patients. In this instance, it seems the ODAC actually read the results of the clinical trial and understood...

Possible good news on the way for BRCA-mutated PCa patients. In this instance, i...

•1 year ago

Efficacy and safety of BAT in CRPC following Abi or Enza resistance: A systematic review

New meta-analysis below [1] [2]. Hard to believe that there are enough BAT studies to perform this particular meta-analysis (i.e. post-Abi/Enza). Now we...

New meta-analysis below [1] [2]. Hard to believe that there are enough BAT stud...

•1 year ago

“Ancient Virus” Therapy for Prostate Cancer Receives DOD Grant, Genetic Engineering & Biotechnology News (GEN), April 27, 2023

The ghost of William B. Coley and his "toxins" live on in new research just funded by DOD. Another one to keep on your radar for future deveopments. From the...

The ghost of William B. Coley and his "toxins" live on in new research just fund...

•1 year ago

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Treatment break?

I was diagnosed 30 months ago with de novo oligometastic pc. (bone and lymph node). Gleason 9. ATM mutation of unknown significance. Underwent RP and then SBRT...

I was diagnosed 30 months ago with de novo oligometastic pc. (bone and lymph nod...

•1 year ago

Clinical Trials: What to Consider

On Tuesday April 25th, 4:30PM Pacific/7.30PM Eastern, (US and Canada) and April 26th 09:30 AM (Canberra, Melbourne and Sydney), the Prostate Cancer...

On Tuesday April 25th, 4:30PM Pacific/7.30PM Eastern, (US and Canada) and Apri...

•1 year ago

Monoamine oxidase A (MAOA): A promising target for prostate cancer therapy

New paper below [1]. {MAOA has been a promising therapy for 20 years imo.} "Previous studies have shown that MAOA is clinically associated with prostate...

New paper below [1]. {MAOA has been a promising therapy for 20 years imo.} "Pr...

•1 year ago

Robust PSA Drops With Radionuclide Therapy in CRPCa— All but one patient had a PSA decline after a fractionated dose of 225Ac-J591

From MedPage Today this article by by Charles Bankhead, Senior Editor, MedPage Today on results on a small pre-clinical trial as reported at the American...

From MedPage Today this article by by Charles Bankhead, Senior Editor, MedPage T...

•1 year ago

PC drugs and Kidney Disease

My husband has kidney disease and I am wondering if any of you out that may also have kidney disease may know of any drugs we need to avoid regarding ADT?...

My husband has kidney disease and I am wondering if any of you out that may also...

•1 year ago

Semaglutide et al

I have never been obese (BMI >=30) but I have certainly been overweight (BMI>=25). There are many PCa papers associating "obesity" with poor survival. BMI is...

I have never been obese (BMI >=30) but I have certainly been overweight (BMI>=25...

•1 year ago

Consulting on next steps

As I am 10 months PSA undetectable and clear on basic bone scans I have started the process of consultation re staying on ADT (zoladex) and Apalutamide...

As I am 10 months PSA undetectable and clear on basic bone scans I have started ...

•1 year ago

T or E2

I'm reading a book by Dr Edward Friedman The New Testosterone Treatment. I am finding it fascinating and confusing. He claims that the acting hormone...

I'm reading a book by Dr Edward Friedman The New Testosterone Treatment. I am fi...

•1 year ago

Cardiovascular Protections from Omega 3 supplements now Doubtful

I have been taking a combined Omega3 supplement (EPA and DHA fish oil)to improve my cardiovascular risk profile along with a statin, baby ASA and careful BP...

I have been taking a combined Omega3 supplement (EPA and DHA fish oil)to improve...

•1 year ago

Financial Toxicity

I was following a trail of links regarding new and developed radiotherapies for advanced PCa. I found a new term that I had not seen before: Financial...

I was following a trail of links regarding new and developed radiotherapies for ...

•1 year ago

Question about radiation

I had prostrate cancer in 2019 and had my prostate removed. My PSA is now detectable at 0.12. It has been at this level since January. My...

I had prostrate cancer in 2019 and had my prostate removed. My PSA is now detect...

•1 year ago

EXTEND - Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic Prostate Cancer

The results of the EXTEND [EXTernal beam radiation to Eliminate Nominal metastatic Disease] Phase II Trial were published in JAMA Oncology this month [1]....

The results of the EXTEND [EXTernal beam radiation to Eliminate Nominal metastat...

•1 year ago

Apology

The two papers I just posted are not newly published. For some reason, PubMed changed my "Most Recent" choice to "Best Match", whater that means. -Patrick

The two papers I just posted are not newly published. For some reason, PubMed c...

•1 year ago

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Oligometastatic prostate cancer: Reality or figment of imagination?

New paper below, [1] full text. Oligometastatic PCa has been controversial from the start, with some denying that it exists. "If you have one met, you have...

New paper below, [1] full text. Oligometastatic PCa has been controversial from...

•1 year ago

The Evolving Role of Diet in Prostate Cancer Risk and Progression

New paper below [1] - full text. I don't recall seeing the journal "Current Opinion in Oncology" before. "Recent data have further solidified the...

New paper below [1] - full text. I don't recall seeing the journal "Current Opi...

•1 year ago

Interesting UK study

https://www.mdlinx.com/journal-summary/active-monitoring-prostatectomy-and-radiotherapy-as-treatment-options-for-localized-prostate-cancer/3V5CGb9IPYQCYp7rKJZof

https://www.mdlinx.com/journal-summary/active-monitoring-prostatectomy-and-radio...

ElRanchoDePoisonIvy

•1 year ago

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Bipolar Androgen Therapy Followed by Androgen Receptor Inhibition as Sequential Therapy for Prostate Cancer

Here's a treat - a review of BAT (Bipolar Androgen Therapy), actually written by Dr. Sam Denmeade [1]. In his intro, he makes a point of stressing that...

Here's a treat - a review of BAT (Bipolar Androgen Therapy), actually written by...

•1 year ago

No Longer Undetectable, PSMA-CT Results

I posted a few days ago about the fact that my husband had been undetectable since his prostate was removed in April of 2021. And then on 3/31 his PSA was 6.3...

I posted a few days ago about the fact that my husband had been undetectable sin...

•1 year ago

Sacral bed sore, agitation ,miserable ,losing my hero , tremor

and feeling abandoned by the one human who promised her nevrlesve me bc even if physically not present we will always be together . It seems he does t want my...

and feeling abandoned by the one human who promised her nevrlesve me bc even if ...

•1 year ago

New Paradigm for PC "Newbies"

Most of us here have already established advanced or even metastatic prostate cancer. Or are here in support of someone who does.) However, many of us are...

Most of us here have already established advanced or even metastatic prostate ca...

•1 year ago

No Longer Undetectable

Hello Everyone, I just posted this on APC, but want to post it on FPC also as I know some of you are not on APC any longer and I am looking for advice. My...

Hello Everyone, I just posted this on APC, but want to post it on FPC also as ...

•1 year ago

Seminal Vesicle Invasion & Senescent tumor cells.

New study below [1]. Note: "p16 (also known as p16INK4a ...), is a protein that slows cell division by slowing the progression of the cell cycle from the G1...

New study below [1]. Note: "p16 (also known as p16INK4a ...), is a protein that...

•1 year ago

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